(25000,48032,'galacturonate binding','F','Interacting selectively and non-covalently with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.','2013-10-27','NSRP'),(25001,48033,'heme o metabolic process','P','The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.','2013-10-27','NSRP'),(25002,48034,'heme O biosynthetic process','P','The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.','2013-10-27','NSRP'),(25003,48035,'heme o catabolic process','P','The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.','2013-10-27','NSRP'),(25004,48036,'central complex development','P','The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.','2013-10-27','NSRP'),(25005,48037,'cofactor binding','F','Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.','2013-10-27','NSRP'),(25006,48038,'quinone binding','F','Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.','2013-10-27','NSRP'),(25007,48039,'ubiquinone binding','F','Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units.','2013-10-27','NSRP'),(25008,48040,'UDP-glucuronate decarboxylase activity','F','Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose.','2013-10-27','NSRP'),(25009,48041,'focal adhesion assembly','P','The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.','2013-10-27','NSRP'),(25010,48042,'regulation of post-mating oviposition','P','Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium, following mating.','2013-10-27','NSRP'),(25011,48045,'trans-pentaprenyltranstransferase activity','F','Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate.','2013-10-27','NSRP'),(25012,48046,'apoplast','C','The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.','2013-10-27','NSRP'),(25013,48047,'mating behavior, sex discrimination','P','The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.','2013-10-27','NSRP'),(25014,48048,'embryonic eye morphogenesis','P','The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.','2013-10-27','NSRP'),(25015,48050,'post-embryonic eye morphogenesis','P','The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.','2013-10-27','NSRP'),(25016,48052,'R1/R6 cell differentiation','P','The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25017,48053,'R1/R6 development','P','The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25018,48054,'R2/R5 cell differentiation','P','The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25019,48055,'R2/R5 development','P','The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25020,48056,'R3/R4 cell differentiation','P','The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25021,48057,'R3/R4 development','P','The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25022,48058,'compound eye corneal lens development','P','The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.','2013-10-27','NSRP'),(25023,48060,'negative gravitaxis','P','The directed movement of a motile cell or organism away from the source of gravity.','2013-10-27','NSRP'),(25024,48061,'positive gravitaxis','P','The directed movement of a motile cell or organism towards the source of gravity.','2013-10-27','NSRP'),(25025,48065,'male courtship behavior, veined wing extension','P','The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25026,48066,'developmental pigmentation','P','The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.','2013-10-27','NSRP'),(25027,48067,'cuticle pigmentation','P','Establishment of a pattern of pigment in the cuticle of an organism.','2013-10-27','NSRP'),(25028,48069,'eye pigmentation','P','Establishment of a pattern of pigment in the eye of an organism.','2013-10-27','NSRP'),(25029,48070,'regulation of developmental pigmentation','P','Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.','2013-10-27','NSRP'),(25030,48071,'sex-specific pigmentation','P','Establishment of a pattern of pigment in one sex that is not observed in the other sex.','2013-10-27','NSRP'),(25031,48072,'compound eye pigmentation','P','Establishment of a pattern of pigment in the compound eye.','2013-10-27','NSRP'),(25032,48073,'regulation of eye pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.','2013-10-27','NSRP'),(25033,48074,'negative regulation of eye pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.','2013-10-27','NSRP'),(25034,48075,'positive regulation of eye pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.','2013-10-27','NSRP'),(25035,48076,'regulation of compound eye pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.','2013-10-27','NSRP'),(25036,48077,'negative regulation of compound eye pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.','2013-10-27','NSRP'),(25037,48078,'positive regulation of compound eye pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.','2013-10-27','NSRP'),(25038,48079,'regulation of cuticle pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.','2013-10-27','NSRP'),(25039,48080,'negative regulation of cuticle pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.','2013-10-27','NSRP'),(25040,48081,'positive regulation of cuticle pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.','2013-10-27','NSRP'),(25041,48082,'regulation of adult chitin-containing cuticle pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.','2013-10-27','NSRP'),(25042,48083,'negative regulation of adult chitin-containing cuticle pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.','2013-10-27','NSRP'),(25043,48084,'positive regulation of adult chitin-containing cuticle pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.','2013-10-27','NSRP'),(25044,48085,'adult chitin-containing cuticle pigmentation','P','Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.','2013-10-27','NSRP'),(25045,48086,'negative regulation of developmental pigmentation','P','Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.','2013-10-27','NSRP'),(25046,48087,'positive regulation of developmental pigmentation','P','Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.','2013-10-27','NSRP'),(25047,48088,'regulation of male pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.','2013-10-27','NSRP'),(25048,48089,'regulation of female pigmentation','P','Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.','2013-10-27','NSRP'),(25049,48090,'negative regulation of female pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.','2013-10-27','NSRP'),(25050,48091,'positive regulation of female pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.','2013-10-27','NSRP'),(25051,48092,'negative regulation of male pigmentation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.','2013-10-27','NSRP'),(25052,48093,'positive regulation of male pigmentation','P','Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.','2013-10-27','NSRP'),(25053,48094,'male pigmentation','P','Establishment of a pattern of pigment in males.','2013-10-27','NSRP'),(25054,48095,'female pigmentation','P','Establishment of a pattern of pigment in females.','2013-10-27','NSRP'),(25055,48096,'chromatin-mediated maintenance of transcription','P','Maintenance of transcription by remodelling of chromatin into an \'open configuration\'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.','2013-10-27','NSRP'),(25056,48097,'long-term maintenance of gene activation','P','Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term.','2013-10-27','NSRP'),(25057,48098,'antennal joint development','P','The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.','2013-10-27','NSRP'),(25058,48099,'anterior/posterior lineage restriction, imaginal disc','P','Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.','2013-10-27','NSRP'),(25059,48100,'wing disc anterior/posterior pattern formation','P','The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.','2013-10-27','NSRP'),(25060,48101,'calcium- and calmodulin-regulated 3\',5\'-cyclic-GMP phosphodiesterase activity','F','Catalysis of the reaction: guanosine 3\',5\'-cyclic phosphate + H2O = guanosine 5\'-phosphate. The reaction is calmodulin and calcium-sensitive.','2013-10-27','NSRP'),(25061,48102,'autophagic cell death','P','A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells.','2013-10-27','NSRP'),(25062,48103,'somatic stem cell division','P','The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.','2013-10-27','NSRP'),(25063,48104,'establishment of body hair or bristle planar orientation','P','Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.','2013-10-27','NSRP'),(25064,48105,'establishment of body hair planar orientation','P','Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.','2013-10-27','NSRP'),(25065,48106,'establishment of thoracic bristle planar orientation','P','Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.','2013-10-27','NSRP'),(25066,48107,'4-amino-3-isothiazolidinone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.','2013-10-27','NSRP'),(25067,48108,'peptide cross-linking via 4-amino-3-isothiazolidinone','P','The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.','2013-10-27','NSRP'),(25068,48109,'peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.','2013-10-27','NSRP'),(25069,48132,'female germ-line stem cell division','P','The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.','2013-10-27','NSRP'),(25070,48133,'male germ-line stem cell division','P','The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.','2013-10-27','NSRP'),(25071,48134,'germ-line cyst formation','P','Formation of a group of interconnected cells derived from a single gonial founder cell.','2013-10-27','NSRP'),(25072,48135,'female germ-line cyst formation','P','Formation of a group of interconnected cells derived from a single female gonial founder cell.','2013-10-27','NSRP'),(25073,48136,'male germ-line cyst formation','P','Formation of a group of interconnected cells derived from a single male gonial founder cell.','2013-10-27','NSRP'),(25074,48137,'spermatocyte division','P','The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.','2013-10-27','NSRP'),(25075,48138,'germ-line cyst encapsulation','P','Formation of a single follicular epithelium around the germ-line derived cells of a cyst.','2013-10-27','NSRP'),(25076,48139,'female germ-line cyst encapsulation','P','Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.','2013-10-27','NSRP'),(25077,48140,'male germ-line cyst encapsulation','P','Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.','2013-10-27','NSRP'),(25078,48142,'germarium-derived cystoblast division','P','The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25079,48143,'astrocyte activation','P','A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.','2013-10-27','NSRP'),(25080,48144,'fibroblast proliferation','P','The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.','2013-10-27','NSRP'),(25081,48145,'regulation of fibroblast proliferation','P','Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.','2013-10-27','NSRP'),(25082,48146,'positive regulation of fibroblast proliferation','P','Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.','2013-10-27','NSRP'),(25083,48147,'negative regulation of fibroblast proliferation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.','2013-10-27','NSRP'),(25084,48148,'behavioral response to cocaine','P','Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.','2013-10-27','NSRP'),(25085,48149,'behavioral response to ethanol','P','Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.','2013-10-27','NSRP'),(25086,48150,'behavioral response to ether','P','Any process that results in a change in the behavior of an organism as a result of an ether stimulus.','2013-10-27','NSRP'),(25087,48151,'hyperphosphorylation','P','OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both.','2013-10-27','NSRP'),(25088,48152,'S100 beta biosynthetic process','P','The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer\'s disease, Down Syndrome and ALS.','2013-10-27','NSRP'),(25089,48153,'S100 alpha biosynthetic process','P','The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer\'s disease, Down Syndrome and ALS.','2013-10-27','NSRP'),(25090,48154,'S100 beta binding','F','Interacting selectively and non-covalently with S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer\'s disease, Down Syndrome and ALS.','2012-03-14','NSRP'),(25091,48155,'S100 alpha binding','F','Interacting selectively and non-covalently with S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer\'s disease, Down Syndrome and ALS.','2012-03-14','NSRP'),(25092,48156,'tau protein binding','F','Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer\'s disease, Down Syndrome and ALS.','2013-10-27','NSRP'),(25093,48158,'oogonium stage','P','The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.','2013-10-27','NSRP'),(25094,48159,'primary oocyte stage','P','The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.','2013-10-27','NSRP'),(25095,48160,'primary follicle stage','P','The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.','2013-10-27','NSRP'),(25096,48161,'double layer follicle stage','P','The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.','2013-10-27','NSRP'),(25097,48162,'multi-layer follicle stage','P','The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani\'s Body) near the germinal vesicle.','2013-10-27','NSRP'),(25098,48163,'scattered antral spaces stage','P','The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.','2013-10-27','NSRP'),(25099,48164,'distinct antral spaces stage','P','The stage in oogenesis when the antral spaces become distinct and the first polar body forms.','2013-10-27','NSRP'),(25100,48165,'fused antrum stage','P','The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.','2013-10-27','NSRP'),(25101,48166,'mature follicle stage','P','The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.','2013-10-27','NSRP'),(25102,48167,'regulation of synaptic plasticity','P','A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.','2013-10-27','NSRP'),(25103,48168,'regulation of neuronal synaptic plasticity','P','A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.','2013-10-27','NSRP'),(25104,48169,'regulation of long-term neuronal synaptic plasticity','P','A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.','2013-10-27','NSRP'),(25105,48170,'positive regulation of long-term neuronal synaptic plasticity','P','A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.','2013-10-27','NSRP'),(25106,48171,'negative regulation of long-term neuronal synaptic plasticity','P','A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.','2013-10-27','NSRP'),(25107,48172,'regulation of short-term neuronal synaptic plasticity','P','A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.','2013-10-27','NSRP'),(25108,48173,'positive regulation of short-term neuronal synaptic plasticity','P','A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.','2013-10-27','NSRP'),(25109,48174,'negative regulation of short-term neuronal synaptic plasticity','P','A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.','2013-10-27','NSRP'),(25110,48175,'hepatocyte growth factor biosynthetic process','P','The chemical reactions and pathways resulting in the formation of hepacyte growth factor. Hepatocyte growth factor is a mitogen for a number of cell types and it is found in liver cells and in many other cell types, including platelets.','2013-10-27','NSRP'),(25111,48176,'regulation of hepatocyte growth factor biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.','2013-10-27','NSRP'),(25112,48177,'positive regulation of hepatocyte growth factor biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.','2013-10-27','NSRP'),(25113,48178,'negative regulation of hepatocyte growth factor biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.','2013-10-27','NSRP'),(25114,48179,'activin receptor complex','C','A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.','2013-10-27','NSRP'),(25115,48180,'activin complex','C','A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.','2013-10-27','NSRP'),(25116,48183,'activin AB complex','C','A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.','2013-10-27','NSRP'),(25117,48184,'follistatin binding','F','OBSOLETE. Interacting selectively and non-covalently with the peptide hormone follistatin.','2013-10-27','NSRP'),(25118,48185,'activin binding','F','Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.','2013-10-27','NSRP'),(25119,48186,'inhibin beta-A binding','F','Interacting selectively and non-covalently with inhibin beta-A.','2012-03-14','NSRP'),(25120,48187,'inhibin beta-B binding','F','Interacting selectively and non-covalently with inhibin beta-B.','2012-03-14','NSRP'),(25121,48188,'Set1C/COMPASS complex','C','A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.','2013-10-27','NSRP'),(25122,48189,'Lid2 complex','C','A protein complex that is thought to be involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid1p, Ash2p, Ecm5p, Snt2p, and Sdc1p.','2013-10-27','NSRP'),(25123,48190,'wing disc dorsal/ventral pattern formation','P','The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.','2013-10-27','NSRP'),(25124,48191,'peptide stabilization activity','F','OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.','2013-10-27','NSRP'),(25125,48192,'peptide antigen stabilization activity','F','OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.','2013-10-27','NSRP'),(25126,48193,'Golgi vesicle transport','P','The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.','2013-10-27','NSRP'),(25127,48194,'Golgi vesicle budding','P','The evagination of the Golgi membrane, resulting in formation of a vesicle.','2013-10-27','NSRP'),(25128,48195,'Golgi membrane priming complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.','2013-10-27','NSRP'),(25129,48196,'plant extracellular matrix','C','The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella.','2013-10-27','NSRP'),(25130,48197,'Golgi membrane coat protein complex assembly','P','The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.','2013-10-27','NSRP'),(25131,48198,'Golgi vesicle bud deformation and release','P','The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.','2013-10-27','NSRP'),(25132,48199,'vesicle targeting, to, from or within Golgi','P','The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.','2013-10-27','NSRP'),(25133,48200,'Golgi transport vesicle coating','P','The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.','2013-10-27','NSRP'),(25134,48201,'vesicle targeting, plasma membrane to endosome','P','The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.','2013-10-27','NSRP'),(25135,48202,'clathrin coating of Golgi vesicle','P','The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.','2013-10-27','NSRP'),(25136,48203,'vesicle targeting, trans-Golgi to endosome','P','The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.','2013-10-27','NSRP'),(25137,48204,'vesicle targeting, inter-Golgi cisterna','P','The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.','2013-10-27','NSRP'),(25138,48205,'COPI coating of Golgi vesicle','P','The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.','2013-10-27','NSRP'),(25139,48206,'vesicle targeting, cis-Golgi to rough ER','P','The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.','2013-10-27','NSRP'),(25140,48207,'vesicle targeting, rough ER to cis-Golgi','P','The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.','2013-10-27','NSRP'),(25141,48208,'COPII vesicle coating','P','The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.','2013-10-27','NSRP'),(25142,48209,'regulation of vesicle targeting, to, from or within Golgi','P','Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.','2013-10-27','NSRP'),(25143,48210,'Golgi vesicle fusion to target membrane','P','The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.','2013-10-27','NSRP'),(25144,48211,'Golgi vesicle docking','P','The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.','2013-10-27','NSRP'),(25145,48212,'Golgi vesicle uncoating','P','The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.','2013-10-27','NSRP'),(25146,48213,'Golgi vesicle prefusion complex stabilization','P','The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.','2013-10-27','NSRP'),(25147,48214,'regulation of Golgi vesicle fusion to target membrane','P','Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.','2013-10-27','NSRP'),(25148,48215,'positive regulation of Golgi vesicle fusion to target membrane','P','Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.','2013-10-27','NSRP'),(25149,48216,'negative regulation of Golgi vesicle fusion to target membrane','P','Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.','2013-10-27','NSRP'),(25150,48217,'pectic matrix','C','The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.','2013-10-27','NSRP'),(25151,48219,'inter-Golgi cisterna vesicle-mediated transport','P','The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.','2013-10-27','NSRP'),(25152,48222,'glycoprotein network','C','An extracellular matrix part that consists of cross-linked glycoproteins.','2013-10-27','NSRP'),(25153,48223,'hemicellulose network','C','Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.','2013-10-27','NSRP'),(25154,48224,'lignin network','C','An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.','2013-10-27','NSRP'),(25155,48225,'suberin network','C','An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.','2013-10-27','NSRP'),(25156,48226,'Casparian strip','C','Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.','2013-10-27','NSRP'),(25157,48227,'plasma membrane to endosome transport','P','Transport of a vesicle from the plasma membrane to the endosome.','2013-10-27','NSRP'),(25158,48228,'actin cortical patch distribution','P','OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.','2013-10-27','NSRP'),(25159,48229,'gametophyte development','P','The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(25160,48232,'male gamete generation','P','Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.','2013-10-27','NSRP'),(25161,48235,'pollen sperm cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.','2013-10-27','NSRP'),(25162,48236,'plant-type spore development','P','The process whose specific outcome is the progression of the spore over time, from its formation to the mature structure. The spore gives rise to gametophytes.','2013-10-27','NSRP'),(25163,48237,'rough endoplasmic reticulum lumen','C','The volume enclosed by the membranes of the rough endoplasmic reticulum.','2013-10-27','NSRP'),(25164,48238,'smooth endoplasmic reticulum lumen','C','The volume enclosed by the membranes of the smooth endoplasmic reticulum.','2013-10-27','NSRP'),(25165,48239,'negative regulation of DNA recombination at telomere','P','Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.','2013-10-27','NSRP'),(25166,48240,'sperm capacitation','P','A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.','2013-10-27','NSRP'),(25167,48241,'epinephrine transport','P','The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(25168,48242,'epinephrine secretion','P','The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.','2013-10-27','NSRP'),(25169,48243,'norepinephrine secretion','P','The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.','2013-10-27','NSRP'),(25170,48244,'phytanoyl-CoA dioxygenase activity','F','Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate.','2013-10-27','NSRP'),(25171,48245,'eosinophil chemotaxis','P','The movement of an eosinophil in response to an external stimulus.','2013-10-27','NSRP'),(25172,48246,'macrophage chemotaxis','P','The movement of a macrophage in response to an external stimulus.','2013-10-27','NSRP'),(25173,48247,'lymphocyte chemotaxis','P','The directed movement of a lymphocyte in response to an external stimulus.','2013-10-27','NSRP'),(25174,48248,'CXCR3 chemokine receptor binding','F','Interacting selectively and non-covalently with a the CXCR3 chemokine receptor.','2013-10-27','NSRP'),(25175,48249,'high affinity phosphate transmembrane transporter activity','F','Catalysis of the transfer of phosphate from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(25176,48250,'mitochondrial iron ion transport','P','The directed movement of iron ions into, out of or within a mitochondrion.','2013-10-27','NSRP'),(25177,48251,'elastic fiber assembly','P','Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.','2013-10-27','NSRP'),(25178,48252,'lauric acid metabolic process','P','The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.','2013-10-27','NSRP'),(25179,48254,'snoRNA localization','P','Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.','2013-10-27','NSRP'),(25180,48255,'mRNA stabilization','P','Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.','2013-10-27','NSRP'),(25181,48256,'flap endonuclease activity','F','Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.','2013-10-27','NSRP'),(25182,48257,'3\'-flap endonuclease activity','F','Catalysis of the cleavage of a 3\' flap structure in DNA, but not other DNA structures; processes the 3\' ends of Okazaki fragments in lagging strand DNA synthesis.','2013-10-27','NSRP'),(25183,48258,'3-ketoglucose-reductase activity','F','Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.','2013-10-27','NSRP'),(25184,48259,'regulation of receptor-mediated endocytosis','P','Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.','2013-10-27','NSRP'),(25185,48260,'positive regulation of receptor-mediated endocytosis','P','Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.','2013-10-27','NSRP'),(25186,48261,'negative regulation of receptor-mediated endocytosis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.','2013-10-27','NSRP'),(25187,48262,'determination of dorsal/ventral asymmetry','P','Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.','2013-10-27','NSRP'),(25188,48263,'determination of dorsal identity','P','Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(25189,48264,'determination of ventral identity','P','The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(25190,48265,'response to pain','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.','2013-10-27','NSRP'),(25191,48266,'behavioral response to pain','P','Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.','2013-10-27','NSRP'),(25192,48268,'clathrin coat assembly','P','The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.','2013-10-27','NSRP'),(25193,48269,'methionine adenosyltransferase complex','C','A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.','2013-10-27','NSRP'),(25194,48270,'methionine adenosyltransferase regulator activity','F','Modulates the activity of methionine adenosyltransferase.','2013-10-27','NSRP'),(25195,48273,'mitogen-activated protein kinase p38 binding','F','Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.','2013-10-27','NSRP'),(25196,48275,'N-terminal peptidyl-arginine acetylation','P','The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase.','2013-10-27','NSRP'),(25197,48277,'nonexocytotic vesicle docking','P','OBSOLETE. The initial attachment of a transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, during a non-exocytotic process.','2013-10-27','NSRP'),(25198,48278,'vesicle docking','P','The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.','2013-10-27','NSRP'),(25199,48279,'vesicle fusion with endoplasmic reticulum','P','The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.','2013-10-27','NSRP'),(25200,48280,'vesicle fusion with Golgi apparatus','P','The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.','2013-10-27','NSRP'),(25201,48281,'inflorescence morphogenesis','P','The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.','2013-10-27','NSRP'),(25202,48282,'determinate inflorescence morphogenesis','P','The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.','2013-10-27','NSRP'),(25203,48283,'indeterminate inflorescence morphogenesis','P','The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.','2013-10-27','NSRP'),(25204,48284,'organelle fusion','P','The creation of a single organelle from two or more organelles.','2013-10-27','NSRP'),(25205,48285,'organelle fission','P','The creation of two or more organelles by division of one organelle.','2013-10-27','NSRP'),(25206,48286,'lung alveolus development','P','The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.','2013-10-27','NSRP'),(25207,48288,'nuclear membrane fusion involved in karyogamy','P','The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.','2013-10-27','NSRP'),(25208,48289,'isotype switching to IgE isotypes','P','The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5\' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.','2013-10-27','NSRP'),(25209,48290,'isotype switching to IgA isotypes','P','The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5\' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.','2013-10-27','NSRP'),(25210,48291,'isotype switching to IgG isotypes','P','The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5\' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.','2013-10-27','NSRP'),(25211,48292,'isotype switching to IgD isotypes','P','The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5\' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.','2013-10-27','NSRP'),(25212,48293,'regulation of isotype switching to IgE isotypes','P','Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.','2013-10-27','NSRP'),(25213,48294,'negative regulation of isotype switching to IgE isotypes','P','Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.','2013-10-27','NSRP'),(25214,48295,'positive regulation of isotype switching to IgE isotypes','P','Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.','2013-10-27','NSRP'),(25215,48296,'regulation of isotype switching to IgA isotypes','P','Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.','2013-10-27','NSRP'),(25216,48297,'negative regulation of isotype switching to IgA isotypes','P','Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.','2013-10-27','NSRP'),(25217,48298,'positive regulation of isotype switching to IgA isotypes','P','Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.','2013-10-27','NSRP'),(25218,48299,'regulation of isotype switching to IgD isotypes','P','Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.','2013-10-27','NSRP'),(25219,48300,'negative regulation of isotype switching to IgD isotypes','P','Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.','2013-10-27','NSRP'),(25220,48301,'positive regulation of isotype switching to IgD isotypes','P','Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.','2013-10-27','NSRP'),(25221,48302,'regulation of isotype switching to IgG isotypes','P','Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.','2013-10-27','NSRP'),(25222,48303,'negative regulation of isotype switching to IgG isotypes','P','Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.','2013-10-27','NSRP'),(25223,48304,'positive regulation of isotype switching to IgG isotypes','P','Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.','2013-10-27','NSRP'),(25224,48305,'immunoglobulin secretion','P','The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.','2013-10-27','NSRP'),(25225,48306,'calcium-dependent protein binding','F','Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.','2013-10-27','NSRP'),(25226,48307,'ferredoxin-nitrite reductase activity','F','Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.','2013-10-27','NSRP'),(25227,48308,'organelle inheritance','P','The partitioning of organelles between daughter cells at cell division.','2013-10-27','NSRP'),(25228,48309,'endoplasmic reticulum inheritance','P','The partitioning of endoplasmic reticulum between daughter cells at cell division.','2013-10-27','NSRP'),(25229,48310,'nucleus inheritance','P','The partitioning of nuclei between daughter cells at cell division.','2013-10-27','NSRP'),(25230,48311,'mitochondrion distribution','P','Any process that establishes the spatial arrangement of mitochondria between and within cells.','2013-10-27','NSRP'),(25231,48312,'intracellular distribution of mitochondria','P','Any process that establishes the spatial arrangement of mitochondria within the cell.','2013-10-27','NSRP'),(25232,48313,'Golgi inheritance','P','The partitioning of Golgi apparatus between daughter cells at cell division.','2013-10-27','NSRP'),(25233,48314,'embryo sac morphogenesis','P','The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.','2013-10-27','NSRP'),(25234,48315,'conidium formation','P','Formation of asexual, nonmotile spores in fungi, by conversion of hyphal elements or arising from specialized sporogenous cells.','2013-10-27','NSRP'),(25235,48316,'seed development','P','The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.','2013-10-27','NSRP'),(25236,48317,'seed morphogenesis','P','The process in which the anatomical structures of the seed are generated and organized.','2013-10-27','NSRP'),(25237,48318,'axial mesoderm development','P','The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.','2013-10-27','NSRP'),(25238,48319,'axial mesoderm morphogenesis','P','The process in which the anatomical structures of the axial mesoderm are generated and organized.','2013-10-27','NSRP'),(25239,48320,'axial mesoderm formation','P','The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.','2013-10-27','NSRP'),(25240,48321,'axial mesodermal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.','2013-10-27','NSRP'),(25241,48322,'axial mesodermal cell fate commitment','P','The process in which a cell becomes committed to become an axial mesoderm cell.','2013-10-27','NSRP'),(25242,48323,'axial mesodermal cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25243,48324,'regulation of axial mesodermal cell fate determination','P','Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.','2013-10-27','NSRP'),(25244,48325,'negative regulation of axial mesodermal cell fate determination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.','2013-10-27','NSRP'),(25245,48326,'positive regulation of axial mesodermal cell fate determination','P','Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.','2013-10-27','NSRP'),(25246,48327,'axial mesodermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25247,48328,'regulation of axial mesodermal cell fate specification','P','Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.','2013-10-27','NSRP'),(25248,48329,'negative regulation of axial mesodermal cell fate specification','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.','2013-10-27','NSRP'),(25249,48330,'positive regulation of axial mesodermal cell fate specification','P','Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.','2013-10-27','NSRP'),(25250,48331,'axial mesoderm structural organization','P','The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25251,48332,'mesoderm morphogenesis','P','The process in which the anatomical structures of the mesoderm are generated and organized.','2013-10-27','NSRP'),(25252,48333,'mesodermal cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.','2013-10-27','NSRP'),(25253,48334,'regulation of mesodermal cell fate determination','P','Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.','2013-10-27','NSRP'),(25254,48335,'negative regulation of mesodermal cell fate determination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.','2013-10-27','NSRP'),(25255,48336,'positive regulation of mesodermal cell fate determination','P','Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.','2013-10-27','NSRP'),(25256,48337,'positive regulation of mesodermal cell fate specification','P','Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.','2013-10-27','NSRP'),(25257,48338,'mesoderm structural organization','P','The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25258,48339,'paraxial mesoderm development','P','The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.','2013-10-27','NSRP'),(25259,48340,'paraxial mesoderm morphogenesis','P','The process in which the anatomical structures of the paraxial mesoderm are generated and organized.','2013-10-27','NSRP'),(25260,48341,'paraxial mesoderm formation','P','The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.','2013-10-27','NSRP'),(25261,48342,'paraxial mesodermal cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.','2013-10-27','NSRP'),(25262,48343,'paraxial mesodermal cell fate commitment','P','The process in which a cell becomes committed to become a paraxial mesoderm cell.','2013-10-27','NSRP'),(25263,48344,'paraxial mesodermal cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25264,48345,'regulation of paraxial mesodermal cell fate determination','P','Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.','2013-10-27','NSRP'),(25265,48346,'positive regulation of paraxial mesodermal cell fate determination','P','Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.','2013-10-27','NSRP'),(25266,48347,'negative regulation of paraxial mesodermal cell fate determination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.','2013-10-27','NSRP'),(25267,48348,'paraxial mesodermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25268,48349,'regulation of paraxial mesodermal cell fate specification','P','Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.','2013-10-27','NSRP'),(25269,48350,'positive regulation of paraxial mesodermal cell fate specification','P','Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.','2013-10-27','NSRP'),(25270,48351,'negative regulation of paraxial mesodermal cell fate specification','P','Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.','2013-10-27','NSRP'),(25271,48352,'paraxial mesoderm structural organization','P','The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25272,48353,'primary endosperm nucleus','C','Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.','2013-10-27','NSRP'),(25273,48354,'mucilage biosynthetic process involved in seed coat development','P','The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.','2013-10-27','NSRP'),(25274,48355,'root cap mucilage biosynthetic process','P','The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.','2013-10-27','NSRP'),(25275,48356,'root epithelial mucilage biosynthetic process','P','The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.','2013-10-27','NSRP'),(25276,48357,'pedicel mucilage biosynthetic process','P','The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.','2013-10-27','NSRP'),(25277,48358,'mucilage pectin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.','2013-10-27','NSRP'),(25278,48359,'mucilage metabolic process involved in seed coat development','P','The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.','2013-10-27','NSRP'),(25279,48360,'root cap mucilage metabolic process','P','The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth.','2013-10-27','NSRP'),(25280,48361,'root epithelial mucilage metabolic process','P','The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.','2013-10-27','NSRP'),(25281,48362,'pedicel mucilage metabolic process','P','The chemical reactions and pathways involving mucilage that occur in the flower stem.','2013-10-27','NSRP'),(25282,48363,'mucilage pectin metabolic process','P','The chemical reactions and pathways involving the pectin component of mucilage.','2013-10-27','NSRP'),(25283,48364,'root development','P','The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.','2013-10-27','NSRP'),(25284,48365,'Rac GTPase binding','F','Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.','2013-10-27','NSRP'),(25285,48366,'leaf development','P','The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25286,48367,'shoot system development','P','The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25287,48368,'lateral mesoderm development','P','The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25288,48369,'lateral mesoderm morphogenesis','P','The process in which the anatomical structures of the lateral mesoderm are generated and organized.','2013-10-27','NSRP'),(25289,48370,'lateral mesoderm formation','P','The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.','2013-10-27','NSRP'),(25290,48371,'lateral mesodermal cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.','2013-10-27','NSRP'),(25291,48372,'lateral mesodermal cell fate commitment','P','The process in which a cell becomes committed to become a lateral mesoderm cell.','2013-10-27','NSRP'),(25292,48373,'lateral mesodermal cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25293,48374,'regulation of lateral mesodermal cell fate determination','P','Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.','2013-10-27','NSRP'),(25294,48375,'negative regulation of lateral mesodermal cell fate determination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.','2013-10-27','NSRP'),(25295,48376,'positive regulation of lateral mesodermal cell fate determination','P','Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.','2013-10-27','NSRP'),(25296,48377,'lateral mesodermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25297,48378,'regulation of lateral mesodermal cell fate specification','P','Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.','2013-10-27','NSRP'),(25298,48379,'positive regulation of lateral mesodermal cell fate specification','P','Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.','2013-10-27','NSRP'),(25299,48380,'negative regulation of lateral mesodermal cell fate specification','P','Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.','2013-10-27','NSRP'),(25300,48381,'lateral mesoderm structural organization','P','The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25301,48382,'mesendoderm development','P','The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.','2013-10-27','NSRP'),(25302,48383,'mesectoderm development','P','The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.','2013-10-27','NSRP'),(25303,48384,'retinoic acid receptor signaling pathway','P','The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(25304,48385,'regulation of retinoic acid receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.','2013-10-27','NSRP'),(25305,48386,'positive regulation of retinoic acid receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.','2013-10-27','NSRP'),(25306,48387,'negative regulation of retinoic acid receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.','2013-10-27','NSRP'),(25307,48388,'endosomal lumen acidification','P','Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.','2013-10-27','NSRP'),(25308,48389,'intermediate mesoderm development','P','The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.','2013-10-27','NSRP'),(25309,48390,'intermediate mesoderm morphogenesis','P','The process in which the anatomical structures of the intermediate mesoderm are generated and organized.','2013-10-27','NSRP'),(25310,48391,'intermediate mesoderm formation','P','The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.','2013-10-27','NSRP'),(25311,48392,'intermediate mesodermal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.','2013-10-27','NSRP'),(25312,48393,'intermediate mesodermal cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.','2013-10-27','NSRP'),(25313,48394,'intermediate mesodermal cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25314,48395,'regulation of intermediate mesodermal cell fate determination','P','Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.','2013-10-27','NSRP'),(25315,48396,'negative regulation of intermediate mesodermal cell fate determination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.','2013-10-27','NSRP'),(25316,48397,'positive regulation of intermediate mesodermal cell fate determination','P','Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.','2013-10-27','NSRP'),(25317,48398,'intermediate mesodermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25318,48399,'regulation of intermediate mesodermal cell fate specification','P','Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.','2013-10-27','NSRP'),(25319,48400,'positive regulation of intermediate mesodermal cell fate specification','P','Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.','2013-10-27','NSRP'),(25320,48401,'negative regulation of intermediate mesodermal cell fate specification','P','Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.','2013-10-27','NSRP'),(25321,48402,'intermediate mesoderm structural organization','P','The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25322,48403,'brain-derived neurotrophic factor binding','F','Interacting selectively and non-covalently with brain-derived neurotrophic factor.','2013-10-27','NSRP'),(25323,48404,'neurotrophin-3 binding','F','Interacting selectively and non-covalently with neurotrophin-3.','2012-03-14','NSRP'),(25324,48405,'neurotrophin-4/5 binding','F','Interacting selectively and non-covalently with neurotrophin-4/5.','2012-03-14','NSRP'),(25325,48406,'nerve growth factor binding','F','Interacting selectively and non-covalently with nerve growth factor (NGF).','2013-10-27','NSRP'),(25326,48407,'platelet-derived growth factor binding','F','Interacting selectively and non-covalently with platelet-derived growth factor.','2013-10-27','NSRP'),(25327,48408,'epidermal growth factor binding','F','Interacting selectively and non-covalently with epidermal growth factor.','2013-10-27','NSRP'),(25328,48437,'floral organ development','P','The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25329,48438,'floral whorl development','P','The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.','2013-10-27','NSRP'),(25330,48439,'flower morphogenesis','P','The process in which the anatomical structures of the flower are generated and organized.','2013-10-27','NSRP'),(25331,48440,'carpel development','P','The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.','2013-10-27','NSRP'),(25332,48441,'petal development','P','The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25333,48442,'sepal development','P','The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25334,48443,'stamen development','P','The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25335,48444,'floral organ morphogenesis','P','The process in which the anatomical structures of the floral organ are generated and organized.','2013-10-27','NSRP'),(25336,48445,'carpel morphogenesis','P','The process in which the anatomical structures of the carpel are generated and organized.','2013-10-27','NSRP'),(25337,48446,'petal morphogenesis','P','The process in which the anatomical structures of the petal are generated and organized.','2013-10-27','NSRP'),(25338,48447,'sepal morphogenesis','P','The process in which the anatomical structures of the sepal are generated and organized.','2013-10-27','NSRP'),(25339,48448,'stamen morphogenesis','P','The process in which the anatomical structures of the stamen are generated and organized.','2013-10-27','NSRP'),(25340,48449,'floral organ formation','P','The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25341,48450,'floral organ structural organization','P','The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25342,48451,'petal formation','P','The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25343,48452,'petal structural organization','P','The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25344,48453,'sepal formation','P','The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25345,48454,'sepal structural organization','P','The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25346,48455,'stamen formation','P','The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25347,48456,'stamen structural organization','P','The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25348,48457,'floral whorl morphogenesis','P','The process in which the anatomical structures of the floral whorl are generated and organized.','2013-10-27','NSRP'),(25349,48458,'floral whorl formation','P','The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25350,48459,'floral whorl structural organization','P','The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25351,48460,'flower formation','P','The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25352,48461,'flower structural organization','P','The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25353,48462,'carpel formation','P','The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(25354,48463,'carpel structural organization','P','The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.','2013-10-27','NSRP'),(25355,48464,'flower calyx development','P','The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25356,48465,'corolla development','P','The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25357,48466,'androecium development','P','The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25358,48467,'gynoecium development','P','The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.','2013-10-27','NSRP'),(25359,48468,'cell development','P','The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.','2013-10-27','NSRP'),(25360,48469,'cell maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.','2013-10-27','NSRP'),(25361,48471,'perinuclear region of cytoplasm','C','Cytoplasm situated near, or occurring around, the nucleus.','2013-10-27','NSRP'),(25362,48472,'threonine-phosphate decarboxylase activity','F','Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2).','2013-10-27','NSRP'),(25363,48473,'D-methionine transport','P','The directed movement of D-methionine into, out of, within, or between cells.','2013-10-27','NSRP'),(25364,48474,'D-methionine transmembrane transporter activity','F','Catalysis of the transfer of D-methionine from one side of a membrane to the other.','2013-10-27','NSRP'),(25365,48475,'coated membrane','C','A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.','2013-10-27','NSRP'),(25366,48476,'Holliday junction resolvase complex','C','A protein complex that mediates the conversion of a Holliday junction into two separate duplex DNA molecules; the complex includes a single- or multisubunit helicase that catalyzes the extension of heteroduplex DNA by branch migration and a nuclease that resolves the junction by nucleolytic cleavage.','2013-10-27','NSRP'),(25367,48477,'oogenesis','P','The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.','2013-10-27','NSRP'),(25368,48478,'replication fork protection','P','Any process that prevents the collapse of stalled replication forks.','2013-10-27','NSRP'),(25369,48479,'style development','P','The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.','2013-10-27','NSRP'),(25370,48480,'stigma development','P','The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.','2013-10-27','NSRP'),(25371,48481,'ovule development','P','The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.','2013-10-27','NSRP'),(25372,48482,'ovule morphogenesis','P','The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.','2013-10-27','NSRP'),(25373,48483,'autonomic nervous system development','P','The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.','2013-10-27','NSRP'),(25374,48484,'enteric nervous system development','P','The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.','2013-10-27','NSRP'),(25375,48485,'sympathetic nervous system development','P','The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.','2013-10-27','NSRP'),(25376,48486,'parasympathetic nervous system development','P','The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.','2013-10-27','NSRP'),(25377,48487,'beta-tubulin binding','F','Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.','2013-10-27','NSRP'),(25378,48488,'synaptic vesicle endocytosis','P','An endocytosis process that results in the invagination of the axonal plasma membrane to create a membrane-bounded vesicle. This process takes up excess membrane that would otherwise accumulate at the presynaptic terminal due to fusion of vesicle membranes during neurotransmitter release. The vesicles created may subsequently be used for neurotransmitter storage and release.','2013-10-27','NSRP'),(25379,48489,'synaptic vesicle transport','P','The directed movement of substances in synaptic membrane-bounded vesicles within the neuron along the cytoskeleton either toward or away from the neuronal cell body.','2013-10-27','NSRP'),(25380,48490,'anterograde synaptic vesicle transport','P','The directed movement of substances in synaptic membrane-bounded vesicles within the neuron, along the cytoskeleton, away from the neuronal cell body.','2013-10-27','NSRP'),(25381,48491,'retrograde synaptic vesicle transport','P','The directed movement of substances in synaptic membrane-bounded vesicles within the neuron, along the cytoskeleton, toward the neuronal cell body.','2013-10-27','NSRP'),(25382,48492,'ribulose bisphosphate carboxylase complex','C','A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.','2013-10-27','NSRP'),(25383,48493,'plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex','C','A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.','2013-10-27','NSRP'),(25384,48494,'chromatophore ribulose bisphosphate carboxylase complex','C','A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.','2013-10-27','NSRP'),(25385,48495,'Roundabout binding','F','Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.','2013-10-27','NSRP'),(25386,48496,'maintenance of organ identity','P','The process in which the identity of an organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(25387,48497,'maintenance of floral organ identity','P','The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(25388,48498,'establishment of petal orientation','P','The process that determines the orientation of petals with reference to the central axis.','2013-10-27','NSRP'),(25389,48499,'synaptic vesicle membrane organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.','2013-10-27','NSRP'),(25390,48500,'signal recognition particle','C','A complex of protein and RNA which facilitates translocation of proteins across membranes.','2013-10-27','NSRP'),(25391,48501,'signal recognition particle, plasma membrane targeting','C','A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.','2013-10-27','NSRP'),(25392,48502,'thiamine-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + thiamine(out) = ADP + phosphate + thiamine(in).','2013-10-27','NSRP'),(25393,48503,'GPI anchor binding','F','OBSOLETE. Interacting selectively with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.','2013-10-27','NSRP'),(25394,48504,'regulation of timing of organ formation','P','Any process that modulates the rate, frequency or extent of organ formation at a consistent predetermined time point during development.','2013-10-27','NSRP'),(25395,48505,'regulation of timing of cell differentiation','P','The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.','2013-10-27','NSRP'),(25396,48506,'regulation of timing of meristematic phase transition','P','Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.','2013-10-27','NSRP'),(25397,48507,'meristem development','P','The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25398,48508,'embryonic meristem development','P','The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25399,48509,'regulation of meristem development','P','Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25400,48510,'regulation of timing of transition from vegetative to reproductive phase','P','The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.','2013-10-27','NSRP'),(25401,48511,'rhythmic process','P','Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.','2013-10-27','NSRP'),(25402,48512,'circadian behavior','P','The specific behavior of an organism that recurs with a regularity of approximately 24 hours.','2013-10-27','NSRP'),(25403,48513,'organ development','P','Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25404,48514,'blood vessel morphogenesis','P','The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.','2013-10-27','NSRP'),(25405,48515,'spermatid differentiation','P','The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25406,48516,'trichome initiation (sensu Magnoliophyta)','P','OBSOLETE. Processes causing the differentiation of an epidermal cell into a trichome cell; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).','2013-10-27','NSRP'),(25407,48517,'positive regulation of trichome initiation (sensu Magnoliophyta)','P','OBSOLETE. Any process that activates or increases the frequency, rate or extent of trichome initiation; as in, but not restricted to, the flowering plants (Magnoliophyta, ncbi_taxonomy_id:3398).','2013-10-27','NSRP'),(25408,48518,'positive regulation of biological process','P','Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.','2013-10-27','NSRP'),(25409,48519,'negative regulation of biological process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.','2013-10-27','NSRP'),(25410,48520,'positive regulation of behavior','P','Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.','2013-10-27','NSRP'),(25411,48521,'negative regulation of behavior','P','Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.','2013-10-27','NSRP'),(25412,48522,'positive regulation of cellular process','P','Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.','2013-10-27','NSRP'),(25413,48523,'negative regulation of cellular process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.','2013-10-27','NSRP'),(25414,48524,'positive regulation of viral process','P','Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.','2013-10-27','NSRP'),(25415,48525,'negative regulation of viral process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.','2013-10-27','NSRP'),(25416,48526,'imaginal disc-derived wing expansion','P','The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.','2013-10-27','NSRP'),(25417,48527,'lateral root development','P','The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.','2013-10-27','NSRP'),(25418,48528,'post-embryonic root development','P','The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25419,48529,'magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity','F','Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.','2013-10-27','NSRP'),(25420,48530,'fruit morphogenesis','P','The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.','2013-10-27','NSRP'),(25421,48531,'beta-1,3-galactosyltransferase activity','F','Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.','2013-10-27','NSRP'),(25422,48532,'anatomical structure arrangement','P','The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.','2013-10-27','NSRP'),(25423,48533,'sporocyte differentiation','P','The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.','2013-10-27','NSRP'),(25424,48534,'hematopoietic or lymphoid organ development','P','The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.','2013-10-27','NSRP'),(25425,48535,'lymph node development','P','The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.','2013-10-27','NSRP'),(25426,48536,'spleen development','P','The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.','2013-10-27','NSRP'),(25427,48537,'mucosal-associated lymphoid tissue development','P','The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.','2013-10-27','NSRP'),(25428,48538,'thymus development','P','The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.','2013-10-27','NSRP'),(25429,48539,'bone marrow development','P','The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25430,48540,'bursa of Fabricius development','P','The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.','2013-10-27','NSRP'),(25431,48541,'Peyer\'s patch development','P','The process whose specific outcome is the progression of Peyer\'s patches over time, from their formation to the mature structure. Peyer\'s patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.','2013-10-27','NSRP'),(25432,48542,'lymph gland development','P','The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.','2013-10-27','NSRP'),(25433,48543,'phytochrome chromophore biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.','2013-10-27','NSRP'),(25434,48544,'recognition of pollen','P','The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species.','2013-10-27','NSRP'),(25435,48545,'response to steroid hormone stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.','2013-10-27','NSRP'),(25436,48546,'digestive tract morphogenesis','P','The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.','2013-10-27','NSRP'),(25437,48548,'regulation of pinocytosis','P','Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally \'cell drinking\'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.','2013-10-27','NSRP'),(25438,48549,'positive regulation of pinocytosis','P','Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally \'cell drinking\'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.','2013-10-27','NSRP'),(25439,48550,'negative regulation of pinocytosis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally \'cell drinking\'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.','2013-10-27','NSRP'),(25440,48551,'metalloenzyme inhibitor activity','F','Stops, prevents or reduces the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(25441,48552,'regulation of metalloenzyme activity','P','Any process that modulates the frequency, rate or extent of activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(25442,48553,'negative regulation of metalloenzyme activity','P','Any process that stops, prevents, or reduces the frequency, rate or extent of activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(25443,48554,'positive regulation of metalloenzyme activity','P','Any process that activates, maintains or increases the rate activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(25444,48555,'generative cell nucleus','C','The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.','2013-10-27','NSRP'),(25445,48556,'microsporocyte nucleus','C','The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.','2013-10-27','NSRP'),(25446,48557,'embryonic digestive tract morphogenesis','P','The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.','2013-10-27','NSRP'),(25447,48559,'establishment of floral organ orientation','P','The process that determines the orientation of the floral organs with reference to the central axis of the flower.','2013-10-27','NSRP'),(25448,48560,'establishment of anatomical structure orientation','P','The process that determines the orientation of an anatomical structure with reference to an axis.','2013-10-27','NSRP'),(25449,48561,'establishment of organ orientation','P','The process that determines the orientation of an organ or tissue with reference to an axis.','2013-10-27','NSRP'),(25450,48562,'embryonic organ morphogenesis','P','Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25451,48563,'post-embryonic organ morphogenesis','P','Morphogenesis, during the post-embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25452,48564,'photosystem I assembly','P','The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.','2013-10-27','NSRP'),(25453,48565,'digestive tract development','P','The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.','2013-10-27','NSRP'),(25454,48566,'embryonic digestive tract development','P','The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.','2013-10-27','NSRP'),(25455,48567,'ectodermal digestive tract morphogenesis','P','The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.','2013-10-27','NSRP'),(25456,48568,'embryonic organ development','P','Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25457,48569,'post-embryonic organ development','P','Development, taking place during the post-embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25458,48570,'notochord morphogenesis','P','The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.','2013-10-27','NSRP'),(25459,48571,'long-day photoperiodism','P','Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the \'critical day length\'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length.','2013-10-27','NSRP'),(25460,48572,'short-day photoperiodism','P','Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the \'critical day length\'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.','2013-10-27','NSRP'),(25461,48573,'photoperiodism, flowering','P','A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the \'critical day length\'. The critical day length varies between species.','2013-10-27','NSRP'),(25462,48574,'long-day photoperiodism, flowering','P','A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.','2013-10-27','NSRP'),(25463,48575,'short-day photoperiodism, flowering','P','A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.','2013-10-27','NSRP'),(25464,48576,'positive regulation of short-day photoperiodism, flowering','P','Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25465,48577,'negative regulation of short-day photoperiodism, flowering','P','Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25466,48578,'positive regulation of long-day photoperiodism, flowering','P','Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25467,48579,'negative regulation of long-day photoperiodism, flowering','P','Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25468,48580,'regulation of post-embryonic development','P','Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.','2013-10-27','NSRP'),(25469,48581,'negative regulation of post-embryonic development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.','2013-10-27','NSRP'),(25470,48582,'positive regulation of post-embryonic development','P','Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.','2013-10-27','NSRP'),(25471,48583,'regulation of response to stimulus','P','Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.','2013-10-27','NSRP'),(25472,48584,'positive regulation of response to stimulus','P','Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.','2013-10-27','NSRP'),(25473,48585,'negative regulation of response to stimulus','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.','2013-10-27','NSRP'),(25474,48586,'regulation of long-day photoperiodism, flowering','P','Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25475,48587,'regulation of short-day photoperiodism, flowering','P','Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.','2013-10-27','NSRP'),(25476,48588,'developmental cell growth','P','The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.','2013-10-27','NSRP'),(25477,48589,'developmental growth','P','The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.','2013-10-27','NSRP'),(25478,48592,'eye morphogenesis','P','The process in which the anatomical structures of the eye are generated and organized.','2013-10-27','NSRP'),(25479,48593,'camera-type eye morphogenesis','P','The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.','2013-10-27','NSRP'),(25480,48596,'embryonic camera-type eye morphogenesis','P','The process in which the anatomical structures of the eye are generated and organized during embryonic development.','2013-10-27','NSRP'),(25481,48597,'post-embryonic camera-type eye morphogenesis','P','The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.','2013-10-27','NSRP'),(25482,48598,'embryonic morphogenesis','P','The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.','2013-10-27','NSRP'),(25483,48599,'oocyte development','P','The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25484,48600,'oocyte fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.','2013-10-27','NSRP'),(25485,48601,'oocyte morphogenesis','P','The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.','2013-10-27','NSRP'),(25486,48602,'fibroblast growth factor 1 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 1.','2012-03-14','NSRP'),(25487,48603,'fibroblast growth factor 2 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 2.','2012-03-14','NSRP'),(25488,48604,'fibroblast growth factor 3 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 3.','2012-03-14','NSRP'),(25489,48605,'fibroblast growth factor 4 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 4.','2012-03-14','NSRP'),(25490,48606,'fibroblast growth factor 5 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 5.','2012-03-14','NSRP'),(25491,48607,'fibroblast growth factor 6 binding','F','Interacting selectively and non-covalently with fibroblast growth factor 6.','2012-03-14','NSRP'),(25492,48608,'reproductive structure development','P','The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.','2013-10-27','NSRP'),(25493,48609,'multicellular organismal reproductive process','P','The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.','2013-10-27','NSRP'),(25494,48610,'cellular process involved in reproduction','P','A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular or single-celled organism.','2013-10-27','NSRP'),(25495,48611,'embryonic ectodermal digestive tract development','P','The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25496,48612,'post-embryonic ectodermal digestive tract development','P','The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25497,48613,'embryonic ectodermal digestive tract morphogenesis','P','The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.','2013-10-27','NSRP'),(25498,48614,'post-embryonic ectodermal digestive tract morphogenesis','P','The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.','2013-10-27','NSRP'),(25499,48615,'embryonic anterior midgut (ectodermal) morphogenesis','P','The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.','2013-10-27','NSRP'),(25500,48616,'post-embryonic anterior midgut (ectodermal) morphogenesis','P','The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.','2013-10-27','NSRP'),(25501,48617,'embryonic foregut morphogenesis','P','The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.','2013-10-27','NSRP'),(25502,48618,'post-embryonic foregut morphogenesis','P','The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.','2013-10-27','NSRP'),(25503,48619,'embryonic hindgut morphogenesis','P','The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.','2013-10-27','NSRP'),(25504,48620,'post-embryonic hindgut morphogenesis','P','The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.','2013-10-27','NSRP'),(25505,48621,'post-embryonic digestive tract morphogenesis','P','The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.','2013-10-27','NSRP'),(25506,48622,'reproductive sporulation','P','OBSOLETE. The formation of reproductive spores.','2013-10-27','NSRP'),(25507,48623,'seed germination on parent plant','P','The process in which a seed germinates before being shed from the parent plant.','2013-10-27','NSRP'),(25508,48624,'plantlet formation on parent plant','P','The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.','2013-10-27','NSRP'),(25509,48625,'myoblast fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(25510,48626,'myoblast fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(25511,48627,'myoblast development','P','The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(25512,48628,'myoblast maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(25513,48629,'trichome patterning','P','The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.','2013-10-27','NSRP'),(25514,48630,'skeletal muscle tissue growth','P','The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.','2013-10-27','NSRP'),(25515,48631,'regulation of skeletal muscle tissue growth','P','Any process that modulates the frequency, rate or extent of skeletal muscle growth.','2013-10-27','NSRP'),(25516,48632,'negative regulation of skeletal muscle tissue growth','P','Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.','2013-10-27','NSRP'),(25517,48633,'positive regulation of skeletal muscle tissue growth','P','Any process that activates, maintains or increases the rate of skeletal muscle growth.','2013-10-27','NSRP'),(25518,48634,'regulation of muscle organ development','P','Any process that modulates the frequency, rate or extent of muscle development.','2013-10-27','NSRP'),(25519,48635,'negative regulation of muscle organ development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.','2013-10-27','NSRP'),(25520,48636,'positive regulation of muscle organ development','P','Any process that activates, maintains or increases the rate of muscle development.','2013-10-27','NSRP'),(25521,48638,'regulation of developmental growth','P','Any process that modulates the frequency, rate or extent of developmental growth.','2013-10-27','NSRP'),(25522,48639,'positive regulation of developmental growth','P','Any process that activates, maintains or increases the rate of developmental growth.','2013-10-27','NSRP'),(25523,48640,'negative regulation of developmental growth','P','Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.','2013-10-27','NSRP'),(25524,48641,'regulation of skeletal muscle tissue development','P','Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.','2013-10-27','NSRP'),(25525,48642,'negative regulation of skeletal muscle tissue development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.','2013-10-27','NSRP'),(25526,48643,'positive regulation of skeletal muscle tissue development','P','Any process that activates, maintains or increases the rate of skeletal muscle tissue development.','2013-10-27','NSRP'),(25527,48644,'muscle organ morphogenesis','P','The process in which the anatomical structures of muscle are generated and organized.','2013-10-27','NSRP'),(25528,48645,'organ formation','P','The process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.','2013-10-27','NSRP'),(25529,48646,'anatomical structure formation involved in morphogenesis','P','The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.','2013-10-27','NSRP'),(25530,48647,'polyphenic determination','P','The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.','2013-10-27','NSRP'),(25531,48648,'caste determination','P','The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.','2013-10-27','NSRP'),(25532,48649,'caste determination, influence by genetic factors','P','The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.','2013-10-27','NSRP'),(25533,48650,'caste determination, influence by environmental factors','P','The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.','2013-10-27','NSRP'),(25534,48651,'polyphenic determination, influence by environmental factors','P','The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.','2013-10-27','NSRP'),(25535,48652,'polyphenic determination, influence by genetic factors','P','The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.','2013-10-27','NSRP'),(25536,48653,'anther development','P','The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25537,48654,'anther morphogenesis','P','The process in which the anatomical structures of the anther are generated and organized.','2013-10-27','NSRP'),(25538,48655,'anther wall tapetum morphogenesis','P','The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.','2013-10-27','NSRP'),(25539,48656,'anther wall tapetum formation','P','The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.','2013-10-27','NSRP'),(25540,48657,'anther wall tapetum cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.','2013-10-27','NSRP'),(25541,48658,'anther wall tapetum development','P','The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25542,48659,'smooth muscle cell proliferation','P','The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.','2013-10-27','NSRP'),(25543,48660,'regulation of smooth muscle cell proliferation','P','Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.','2013-10-27','NSRP'),(25544,48661,'positive regulation of smooth muscle cell proliferation','P','Any process that activates or increases the rate or extent of smooth muscle cell proliferation.','2013-10-27','NSRP'),(25545,48662,'negative regulation of smooth muscle cell proliferation','P','Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.','2013-10-27','NSRP'),(25546,48663,'neuron fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.','2013-10-27','NSRP'),(25547,48664,'neuron fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25548,48665,'neuron fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25549,48666,'neuron development','P','The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25550,48667,'cell morphogenesis involved in neuron differentiation','P','The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.','2013-10-27','NSRP'),(25551,48668,'collateral sprouting','P','The process in which outgrowths develop from the shafts of existing axons.','2013-10-27','NSRP'),(25552,48669,'collateral sprouting in absence of injury','P','The process in which outgrowths develop from the axons of intact undamaged neurons.','2013-10-27','NSRP'),(25553,48670,'regulation of collateral sprouting','P','Any process that modulates the frequency, rate or extent of collateral sprouting.','2013-10-27','NSRP'),(25554,48671,'negative regulation of collateral sprouting','P','Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.','2013-10-27','NSRP'),(25555,48672,'positive regulation of collateral sprouting','P','Any process that activates or increases the frequency, rate or extent of collateral sprouting.','2013-10-27','NSRP'),(25556,48673,'collateral sprouting of intact axon in response to injury','P','The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.','2013-10-27','NSRP'),(25557,48674,'collateral sprouting of injured axon','P','The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.','2013-10-27','NSRP'),(25558,48675,'axon extension','P','Long distance growth of a single axon process involved in cellular development.','2013-10-27','NSRP'),(25559,48676,'axon extension involved in development','P','Long distance growth of a single axon process involved in cellular development.','2012-03-14','NSRP');
INSERT INTO `GO` VALUES (25560,48677,'axon extension involved in regeneration','P','Long distance growth of a single axon process involved in regeneration of the neuron.','2013-10-27','NSRP'),(25561,48678,'response to axon injury','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.','2013-10-27','NSRP'),(25562,48679,'regulation of axon regeneration','P','Any process that modulates the frequency, rate or extent of axon regeneration.','2013-10-27','NSRP'),(25563,48680,'positive regulation of axon regeneration','P','Any process that activates, maintains or increases the rate of axon regeneration.','2013-10-27','NSRP'),(25564,48681,'negative regulation of axon regeneration','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.','2013-10-27','NSRP'),(25565,48682,'sprouting of injured axon','P','The process involved in sprouting of an injured axon.','2013-10-27','NSRP'),(25566,48683,'regulation of collateral sprouting of intact axon in response to injury','P','Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.','2013-10-27','NSRP'),(25567,48684,'positive regulation of collateral sprouting of intact axon in response to injury','P','Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.','2013-10-27','NSRP'),(25568,48685,'negative regulation of collateral sprouting of intact axon in response to injury','P','Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.','2013-10-27','NSRP'),(25569,48686,'regulation of sprouting of injured axon','P','Any process that modulates the frequency, rate or extent of sprouting of an injured axon.','2013-10-27','NSRP'),(25570,48687,'positive regulation of sprouting of injured axon','P','Any process that activates, maintains or increases the rate of sprouting of an injured axon.','2013-10-27','NSRP'),(25571,48688,'negative regulation of sprouting of injured axon','P','Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.','2013-10-27','NSRP'),(25572,48689,'formation of growth cone in injured axon','P','The formation of a growth cone in an injured axon.','2013-10-27','NSRP'),(25573,48690,'regulation of axon extension involved in regeneration','P','Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.','2013-10-27','NSRP'),(25574,48691,'positive regulation of axon extension involved in regeneration','P','Any process that activates, maintains or increases the rate of axon extension involved in regeneration.','2013-10-27','NSRP'),(25575,48692,'negative regulation of axon extension involved in regeneration','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.','2013-10-27','NSRP'),(25576,48693,'regulation of collateral sprouting of injured axon','P','Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.','2013-10-27','NSRP'),(25577,48694,'positive regulation of collateral sprouting of injured axon','P','Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.','2013-10-27','NSRP'),(25578,48695,'negative regulation of collateral sprouting of injured axon','P','Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.','2013-10-27','NSRP'),(25579,48696,'regulation of collateral sprouting in absence of injury','P','Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.','2013-10-27','NSRP'),(25580,48697,'positive regulation of collateral sprouting in absence of injury','P','Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.','2013-10-27','NSRP'),(25581,48698,'negative regulation of collateral sprouting in absence of injury','P','Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.','2013-10-27','NSRP'),(25582,48699,'generation of neurons','P','The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.','2013-10-27','NSRP'),(25583,48700,'acquisition of desiccation tolerance in seed','P','The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.','2013-10-27','NSRP'),(25584,48701,'embryonic cranial skeleton morphogenesis','P','The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.','2013-10-27','NSRP'),(25585,48702,'embryonic neurocranium morphogenesis','P','The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.','2013-10-27','NSRP'),(25586,48703,'embryonic viscerocranium morphogenesis','P','The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.','2013-10-27','NSRP'),(25587,48704,'embryonic skeletal system morphogenesis','P','The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.','2013-10-27','NSRP'),(25588,48705,'skeletal system morphogenesis','P','The process in which the anatomical structures of the skeleton are generated and organized.','2013-10-27','NSRP'),(25589,48706,'embryonic skeletal system development','P','The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25590,48707,'instar larval or pupal morphogenesis','P','The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.','2013-10-27','NSRP'),(25591,48708,'astrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.','2013-10-27','NSRP'),(25592,48709,'oligodendrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.','2013-10-27','NSRP'),(25593,48710,'regulation of astrocyte differentiation','P','Any process that modulates the frequency, rate or extent of astrocyte differentiation.','2013-10-27','NSRP'),(25594,48711,'positive regulation of astrocyte differentiation','P','Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.','2013-10-27','NSRP'),(25595,48712,'negative regulation of astrocyte differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.','2013-10-27','NSRP'),(25596,48713,'regulation of oligodendrocyte differentiation','P','Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.','2013-10-27','NSRP'),(25597,48714,'positive regulation of oligodendrocyte differentiation','P','Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.','2013-10-27','NSRP'),(25598,48715,'negative regulation of oligodendrocyte differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.','2013-10-27','NSRP'),(25599,48716,'labrum morphogenesis','P','The process in which the anatomical structures of labrum are generated and organized.','2013-10-27','NSRP'),(25600,48717,'anterior cibarial plate morphogenesis','P','The process in which the anatomical structures of the anterior cibarial plate are generated and organized.','2013-10-27','NSRP'),(25601,48718,'cibarial fish-trap bristle morphogenesis','P','The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.','2013-10-27','NSRP'),(25602,48719,'epistomal sclerite morphogenesis','P','The process in which the anatomical structures of the epistomal sclerite are generated and organized.','2013-10-27','NSRP'),(25603,48720,'posterior cibarial plate morphogenesis','P','The process in which the anatomical structures of the posterior cibarial plate are generated and organized.','2013-10-27','NSRP'),(25604,48721,'clypeus morphogenesis','P','The process in which the anatomical structures of the clypeus are generated and organized.','2013-10-27','NSRP'),(25605,48722,'anterior cibarial plate development','P','The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.','2013-10-27','NSRP'),(25606,48723,'clypeus development','P','The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect\'s head.','2013-10-27','NSRP'),(25607,48724,'epistomal sclerite development','P','The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25608,48725,'cibarial fish-trap bristle development','P','The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.','2013-10-27','NSRP'),(25609,48726,'labrum development','P','The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25610,48727,'posterior cibarial plate development','P','The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25611,48728,'proboscis development','P','The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25612,48729,'tissue morphogenesis','P','The process in which the anatomical structures of a tissue are generated and organized.','2013-10-27','NSRP'),(25613,48730,'epidermis morphogenesis','P','The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of a plant or animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.','2013-10-27','NSRP'),(25614,48731,'system development','P','The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.','2013-10-27','NSRP'),(25615,48732,'gland development','P','The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.','2013-10-27','NSRP'),(25616,48733,'sebaceous gland development','P','The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25617,48734,'proboscis morphogenesis','P','The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.','2013-10-27','NSRP'),(25618,48735,'haltere morphogenesis','P','The process in which the anatomical structures of a haltere are generated and organized.','2013-10-27','NSRP'),(25619,48736,'appendage development','P','The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.','2013-10-27','NSRP'),(25620,48737,'imaginal disc-derived appendage development','P','The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.','2013-10-27','NSRP'),(25621,48738,'cardiac muscle tissue development','P','The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25622,48739,'cardiac muscle fiber development','P','The process whose specific outcome is the progression of cardiac muscle fiber over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25623,48740,'striated muscle fiber development','P','OBSOLETE. The process whose specific outcome is the amplification and progression of myoblasts (muscle precursor cells) into terminally differentiated multinucleated muscle fibers.','2013-10-27','NSRP'),(25624,48741,'skeletal muscle fiber development','P','The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.','2013-10-27','NSRP'),(25625,48742,'regulation of skeletal muscle fiber development','P','Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.','2013-10-27','NSRP'),(25626,48743,'positive regulation of skeletal muscle fiber development','P','Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.','2013-10-27','NSRP'),(25627,48744,'negative regulation of skeletal muscle fiber development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.','2013-10-27','NSRP'),(25628,48745,'smooth muscle tissue development','P','The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25629,48746,'smooth muscle fiber development','P','OBSOLETE. The process whose specific outcome is the progression of smooth muscle fiber over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25630,48747,'muscle fiber development','P','The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.','2013-10-27','NSRP'),(25631,48749,'compound eye development','P','The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.','2013-10-27','NSRP'),(25632,48750,'compound eye corneal lens morphogenesis','P','The process in which the anatomical structures of the compound eye corneal lens are generated and organized.','2013-10-27','NSRP'),(25633,48752,'semicircular canal morphogenesis','P','The process in which the anatomical structures of the semicircular canals are generated and organized.','2013-10-27','NSRP'),(25634,48753,'pigment granule organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.','2013-10-27','NSRP'),(25635,48754,'branching morphogenesis of an epithelial tube','P','The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.','2013-10-27','NSRP'),(25636,48755,'branching morphogenesis of a nerve','P','The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).','2013-10-27','NSRP'),(25637,48756,'sieve cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.','2013-10-27','NSRP'),(25638,48757,'pigment granule maturation','P','Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.','2013-10-27','NSRP'),(25639,48758,'companion cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.','2013-10-27','NSRP'),(25640,48759,'xylem vessel member cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.','2013-10-27','NSRP'),(25641,48760,'parenchymal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.','2013-10-27','NSRP'),(25642,48761,'collenchyma cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.','2013-10-27','NSRP'),(25643,48762,'mesenchymal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.','2013-10-27','NSRP'),(25644,48763,'calcium-induced calcium release activity','F','Release of calcium ions from an intracellular vesicle on induction by increased calcium concentration.','2013-10-27','NSRP'),(25645,48764,'trichoblast maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.','2013-10-27','NSRP'),(25646,48765,'root hair cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.','2013-10-27','NSRP'),(25647,48766,'root hair initiation','P','The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.','2013-10-27','NSRP'),(25648,48767,'root hair elongation','P','The process in which the root hair grows longer.','2013-10-27','NSRP'),(25649,48768,'root hair cell tip growth','P','Localized growth of a plant root hair tip by extension of the cell wall.','2013-10-27','NSRP'),(25650,48769,'sarcomerogenesis','P','The process in which sarcomeres are added in series within a fiber.','2013-10-27','NSRP'),(25651,48770,'pigment granule','C','A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.','2013-10-27','NSRP'),(25652,48771,'tissue remodeling','P','The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.','2013-10-27','NSRP'),(25653,48772,'leucophore differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.','2013-10-27','NSRP'),(25654,48773,'erythrophore differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.','2013-10-27','NSRP'),(25655,48774,'cyanophore differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.','2013-10-27','NSRP'),(25656,48775,'regulation of leucophore differentiation','P','Any process that modulates the frequency, rate or extent of leucophore differentiation.','2013-10-27','NSRP'),(25657,48776,'negative regulation of leucophore differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.','2013-10-27','NSRP'),(25658,48777,'positive regulation of leucophore differentiation','P','Any process that activates or increases the frequency, rate or extent of leucophore differentiation.','2013-10-27','NSRP'),(25659,48778,'regulation of erythrophore differentiation','P','Any process that modulates the frequency, rate or extent of erythrophore differentiation.','2013-10-27','NSRP'),(25660,48779,'negative regulation of erythrophore differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.','2013-10-27','NSRP'),(25661,48780,'positive regulation of erythrophore differentiation','P','Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.','2013-10-27','NSRP'),(25662,48781,'regulation of cyanophore differentiation','P','Any process that modulates the frequency, rate or extent of cyanophore differentiation.','2013-10-27','NSRP'),(25663,48782,'negative regulation of cyanophore differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.','2013-10-27','NSRP'),(25664,48783,'positive regulation of cyanophore differentiation','P','Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.','2013-10-27','NSRP'),(25665,48784,'pigment biosynthetic process involved in pigment granule maturation','P','The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.','2013-10-27','NSRP'),(25666,48785,'hatching gland development','P','The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.','2013-10-27','NSRP'),(25667,48786,'presynaptic active zone','C','A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix.','2013-10-27','NSRP'),(25668,48787,'presynaptic active zone membrane','C','The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.','2013-10-27','NSRP'),(25669,48788,'presynaptic cytoskeletal matrix assembled at active zones','C','The specialized cytoskeletal matrix assembled at the active zones of the presynaptic nerve terminal. The cytoskeletal matrix is a proteinaceous structure involved in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. The cytomatrix protein exclusively assembled at active zones, is thought to form a molecular scaffold that organizes neurotransmitter release sites.','2013-10-27','NSRP'),(25670,48789,'cytoskeletal matrix organization at active zone','P','The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.','2013-10-27','NSRP'),(25671,48790,'maintenance of presynaptic active zone structure','P','The process in which a neuronal cell maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and dock of vesicles and the release of neurotransmitters.','2013-10-27','NSRP'),(25672,48791,'calcium ion-dependent exocytosis of neurotransmitter','P','The release of a neurotransmitter into the synaptic cleft, where the release step is dependent on the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.','2013-10-27','NSRP'),(25673,48792,'calcium ion-independent exocytosis of neurotransmitter','P','The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.','2013-10-27','NSRP'),(25674,48793,'pronephros development','P','The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.','2013-10-27','NSRP'),(25675,48794,'swim bladder development','P','The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.','2013-10-27','NSRP'),(25676,48795,'swim bladder morphogenesis','P','The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.','2013-10-27','NSRP'),(25677,48796,'swim bladder maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.','2013-10-27','NSRP'),(25678,48797,'swim bladder formation','P','The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.','2013-10-27','NSRP'),(25679,48798,'swim bladder inflation','P','The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.','2013-10-27','NSRP'),(25680,48799,'organ maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for an organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.','2013-10-27','NSRP'),(25681,48800,'antennal morphogenesis','P','The process in which the anatomical structures of the antenna are generated and organized.','2013-10-27','NSRP'),(25682,48801,'antennal joint morphogenesis','P','The process in which the anatomical structures of the antennal joint are generated and organized.','2013-10-27','NSRP'),(25683,48802,'notum morphogenesis','P','The process in which the anatomical structures of the dorsal part of the body are generated and organized.','2013-10-27','NSRP'),(25684,48803,'imaginal disc-derived male genitalia morphogenesis','P','The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.','2013-10-27','NSRP'),(25685,48804,'imaginal disc-derived female genitalia morphogenesis','P','The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.','2013-10-27','NSRP'),(25686,48805,'imaginal disc-derived genitalia morphogenesis','P','The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.','2013-10-27','NSRP'),(25687,48806,'genitalia development','P','The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25688,48807,'female genitalia morphogenesis','P','The process in which the anatomical structures of female genitalia are generated and organized.','2013-10-27','NSRP'),(25689,48808,'male genitalia morphogenesis','P','The process in which the anatomical structures of male genitalia are generated and organized.','2013-10-27','NSRP'),(25690,48809,'analia morphogenesis','P','The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.','2013-10-27','NSRP'),(25691,48810,'female analia morphogenesis','P','The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(25692,48811,'male analia morphogenesis','P','The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.','2013-10-27','NSRP'),(25693,48812,'neuron projection morphogenesis','P','The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.','2013-10-27','NSRP'),(25694,48813,'dendrite morphogenesis','P','The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.','2013-10-27','NSRP'),(25695,48814,'regulation of dendrite morphogenesis','P','Any process that modulates the frequency, rate or extent of dendrite morphogenesis.','2013-10-27','NSRP'),(25696,48815,'hermaphrodite genitalia morphogenesis','P','The process in which the anatomical structures of hermaphrodite genitalia are generated and organized.','2013-10-27','NSRP'),(25697,48816,'ocellus morphogenesis','P','The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.','2013-10-27','NSRP'),(25698,48817,'negative regulation of hair follicle maturation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.','2013-10-27','NSRP'),(25699,48818,'positive regulation of hair follicle maturation','P','Any process that activates or increases the frequency, rate or extent of hair follicle maturation.','2013-10-27','NSRP'),(25700,48819,'regulation of hair follicle maturation','P','Any process that modulates the frequency, rate or extent of hair follicle maturation.','2013-10-27','NSRP'),(25701,48820,'hair follicle maturation','P','A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.','2013-10-27','NSRP'),(25702,48821,'erythrocyte development','P','The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25703,48822,'enucleate erythrocyte development','P','The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25704,48823,'nucleate erythrocyte development','P','The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25705,48824,'pigment cell precursor differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.','2013-10-27','NSRP'),(25706,48825,'cotyledon development','P','The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.','2013-10-27','NSRP'),(25707,48826,'cotyledon morphogenesis','P','The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.','2013-10-27','NSRP'),(25708,48827,'phyllome development','P','The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.','2013-10-27','NSRP'),(25709,48829,'root cap development','P','The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.','2013-10-27','NSRP'),(25710,48830,'adventitious root development','P','The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.','2013-10-27','NSRP'),(25711,48831,'regulation of shoot system development','P','Any process that modulates the frequency, rate or extent of shoot development.','2013-10-27','NSRP'),(25712,48832,'specification of organ number','P','The regionalization process that modulates the quantity of a particular type of organ.','2013-10-27','NSRP'),(25713,48833,'specification of floral organ number','P','Any process that modulates the number of floral organs formed in a floral whorl.','2013-10-27','NSRP'),(25714,48834,'specification of petal number','P','Any process that modulates the number of petals formed in a flower.','2013-10-27','NSRP'),(25715,48835,'specification of decreased petal number','P','Any process that reduces the number of petals produced in a developing flower.','2013-10-27','NSRP'),(25716,48836,'specification of increased petal number','P','Any process that increases the number of petals produced in a developing flower.','2013-10-27','NSRP'),(25717,48837,'sorus development','P','The process whose specific outcome is the progression of the sorus over time, from its formation to the mature structure. A sorus is a mass of spores.','2013-10-27','NSRP'),(25718,48838,'release of seed from dormancy','P','The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.','2013-10-27','NSRP'),(25719,48839,'inner ear development','P','The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25720,48840,'otolith development','P','The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25721,48841,'regulation of axon extension involved in axon guidance','P','Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.','2013-10-27','NSRP'),(25722,48842,'positive regulation of axon extension involved in axon guidance','P','Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.','2013-10-27','NSRP'),(25723,48843,'negative regulation of axon extension involved in axon guidance','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.','2013-10-27','NSRP'),(25724,48844,'artery morphogenesis','P','The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.','2013-10-27','NSRP'),(25725,48845,'venous blood vessel morphogenesis','P','The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.','2013-10-27','NSRP'),(25726,48846,'axon extension involved in axon guidance','P','The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.','2013-10-27','NSRP'),(25727,48847,'adenohypophysis formation','P','The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.','2013-10-27','NSRP'),(25728,48848,'neurohypophysis morphogenesis','P','The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.','2013-10-27','NSRP'),(25729,48849,'neurohypophysis formation','P','The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.','2013-10-27','NSRP'),(25730,48850,'hypophysis morphogenesis','P','The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.','2013-10-27','NSRP'),(25731,48851,'hypophysis formation','P','The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.','2013-10-27','NSRP'),(25732,48852,'diencephalon morphogenesis','P','The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.','2013-10-27','NSRP'),(25733,48853,'forebrain morphogenesis','P','The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).','2013-10-27','NSRP'),(25734,48854,'brain morphogenesis','P','The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).','2013-10-27','NSRP'),(25735,48855,'adenohypophysis morphogenesis','P','The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.','2013-10-27','NSRP'),(25736,48856,'anatomical structure development','P','The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.','2013-10-27','NSRP'),(25737,48857,'neural nucleus development','P','The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.','2013-10-27','NSRP'),(25738,48858,'cell projection morphogenesis','P','The process in which the anatomical structures of a cell projection are generated and organized.','2013-10-27','NSRP'),(25739,48859,'formation of anatomical boundary','P','The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.','2013-10-27','NSRP'),(25740,48860,'glioblast division','P','The process resulting in the physical partitioning and separation of a glioblast into daughter cells.','2013-10-27','NSRP'),(25741,48861,'leukemia inhibitory factor signaling pathway','P','Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(25742,48863,'stem cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.','2013-10-27','NSRP'),(25743,48864,'stem cell development','P','The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.','2013-10-27','NSRP'),(25744,48865,'stem cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.','2013-10-27','NSRP'),(25745,48866,'stem cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(25746,48867,'stem cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(25747,48868,'pollen tube development','P','The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.','2013-10-27','NSRP'),(25748,48869,'cellular developmental process','P','A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.','2013-10-27','NSRP'),(25749,48870,'cell motility','P','Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.','2013-10-27','NSRP'),(25750,48871,'multicellular organismal homeostasis','P','Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.','2013-10-27','NSRP'),(25751,48872,'homeostasis of number of cells','P','Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.','2013-10-27','NSRP'),(25752,48873,'homeostasis of number of cells within a tissue','P','Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.','2013-10-27','NSRP'),(25753,48874,'homeostasis of number of cells in a free-living population','P','The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.','2013-10-27','NSRP'),(25754,48875,'chemical homeostasis within a tissue','P','Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue.','2013-10-27','NSRP'),(25755,48876,'chemical homeostasis within retina','P','Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina.','2013-10-27','NSRP'),(25756,48877,'homeostasis of number of retina cells','P','Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.','2013-10-27','NSRP'),(25757,48878,'chemical homeostasis','P','Any biological process involved in the maintenance of an internal steady state of a chemical.','2013-10-27','NSRP'),(25758,48880,'sensory system development','P','The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.','2013-10-27','NSRP'),(25759,48881,'mechanosensory lateral line system development','P','The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.','2013-10-27','NSRP'),(25760,48882,'lateral line development','P','The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.','2013-10-27','NSRP'),(25761,48883,'neuromast primordium migration','P','The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.','2013-10-27','NSRP'),(25762,48884,'neuromast development','P','The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.','2013-10-27','NSRP'),(25763,48885,'neuromast deposition','P','The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.','2013-10-27','NSRP'),(25764,48886,'neuromast hair cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.','2013-10-27','NSRP'),(25765,48887,'cupula development','P','The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.','2013-10-27','NSRP'),(25766,48888,'neuromast mantle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.','2013-10-27','NSRP'),(25767,48889,'neuromast support cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.','2013-10-27','NSRP'),(25768,48890,'lateral line ganglion development','P','The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.','2013-10-27','NSRP'),(25769,48891,'lateral line ganglion neuron differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.','2013-10-27','NSRP'),(25770,48892,'lateral line nerve development','P','The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.','2013-10-27','NSRP'),(25771,48893,'afferent axon development in lateral line nerve','P','The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.','2013-10-27','NSRP'),(25772,48894,'efferent axon development in a lateral line nerve','P','The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.','2013-10-27','NSRP'),(25773,48895,'lateral line nerve glial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.','2013-10-27','NSRP'),(25774,48896,'lateral line nerve glial cell migration','P','The movement of a glial cell along the axons in a lateral line nerve.','2013-10-27','NSRP'),(25775,48897,'myelination of lateral line nerve axons','P','The formation of compact myelin sheaths around the axons of a lateral line nerve.','2013-10-27','NSRP'),(25776,48898,'anterior lateral line system development','P','The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.','2013-10-27','NSRP'),(25777,48899,'anterior lateral line development','P','The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.','2013-10-27','NSRP'),(25778,48900,'anterior lateral line neuromast primordium migration','P','The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.','2013-10-27','NSRP'),(25779,48901,'anterior lateral line neuromast development','P','The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.','2013-10-27','NSRP'),(25780,48902,'anterior lateral line neuromast deposition','P','The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.','2013-10-27','NSRP'),(25781,48903,'anterior lateral line neuromast hair cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.','2013-10-27','NSRP'),(25782,48904,'anterior lateral line neuromast cupula development','P','The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.','2013-10-27','NSRP'),(25783,48905,'anterior lateral line neuromast mantle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.','2013-10-27','NSRP'),(25784,48906,'anterior lateral line neuromast support cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.','2013-10-27','NSRP'),(25785,48907,'anterior lateral line ganglion development','P','The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.','2013-10-27','NSRP'),(25786,48908,'anterior lateral line ganglion neuron differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.','2013-10-27','NSRP'),(25787,48909,'anterior lateral line nerve development','P','The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.','2013-10-27','NSRP'),(25788,48910,'afferent axon development in anterior lateral line nerve','P','The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.','2013-10-27','NSRP'),(25789,48911,'efferent axon development in anterior lateral line nerve','P','The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.','2013-10-27','NSRP'),(25790,48912,'glial cell migration in anterior lateral line nerve','P','The movement of a glial cell along the axons in the anterior lateral line nerve.','2013-10-27','NSRP'),(25791,48913,'anterior lateral line nerve glial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.','2013-10-27','NSRP'),(25792,48914,'myelination of anterior lateral line nerve axons','P','The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.','2013-10-27','NSRP'),(25793,48915,'posterior lateral line system development','P','The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.','2013-10-27','NSRP'),(25794,48916,'posterior lateral line development','P','The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.','2013-10-27','NSRP'),(25795,48917,'posterior lateral line ganglion development','P','The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.','2013-10-27','NSRP'),(25796,48918,'posterior lateral line nerve development','P','The process whose specific outcome is the progression of the posterior lateral line nerve over time, form its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.','2013-10-27','NSRP'),(25797,48919,'posterior lateral line neuromast development','P','The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.','2013-10-27','NSRP'),(25798,48920,'posterior lateral line neuromast primordium migration','P','The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.','2013-10-27','NSRP'),(25799,48921,'posterior lateral line neuromast cupula development','P','The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.','2013-10-27','NSRP'),(25800,48922,'posterior lateral line neuromast deposition','P','The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.','2013-10-27','NSRP'),(25801,48923,'posterior lateral line neuromast hair cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.','2013-10-27','NSRP'),(25802,48924,'posterior lateral line neuromast mantle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.','2013-10-27','NSRP'),(25803,48925,'lateral line system development','P','The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.','2013-10-27','NSRP'),(25804,48926,'electrosensory lateral line system development','P','The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.','2013-10-27','NSRP'),(25805,48927,'posterior lateral line neuromast support cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.','2013-10-27','NSRP'),(25806,48928,'posterior lateral line ganglion neuron differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.','2013-10-27','NSRP'),(25807,48929,'efferent axon development in posterior lateral line nerve','P','The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.','2013-10-27','NSRP'),(25808,48930,'glial cell migration in posterior lateral line nerve','P','The movement of a glial cell along the axons in the posterior lateral line nerve.','2013-10-27','NSRP'),(25809,48931,'posterior lateral line nerve glial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.','2013-10-27','NSRP'),(25810,48932,'myelination of posterior lateral line nerve axons','P','The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.','2013-10-27','NSRP'),(25811,48933,'afferent axon development in posterior lateral line nerve','P','The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.','2013-10-27','NSRP'),(25812,48934,'peripheral nervous system neuron differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.','2013-10-27','NSRP'),(25813,48935,'peripheral nervous system neuron development','P','The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.','2013-10-27','NSRP'),(25814,48936,'peripheral nervous system neuron axonogenesis','P','Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.','2013-10-27','NSRP'),(25815,48937,'lateral line nerve glial cell development','P','The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25816,48938,'lateral line nerve glial cell morphogenesis involved in differentiation','P','The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.','2013-10-27','NSRP'),(25817,48939,'anterior lateral line nerve glial cell development','P','The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25818,48940,'anterior lateral line nerve glial cell morphogenesis involved in differentiation','P','The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.','2013-10-27','NSRP'),(25819,48941,'posterior lateral line nerve glial cell development','P','The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(25820,48942,'posterior lateral line nerve glial cell morphogenesis involved in differentiation','P','The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.','2013-10-27','NSRP'),(25821,50000,'chromosome localization','P','Any process in which a chromosome is transported to, or maintained in, a specific location.','2013-10-27','NSRP'),(25822,50001,'D-glutaminase activity','F','Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate.','2013-10-27','NSRP'),(25823,50002,'D-proline reductase (dithiol) activity','F','Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline.','2013-10-27','NSRP'),(25824,50003,'deoxycytidylate C-methyltransferase activity','F','Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2\'-deoxy-5-methyl-5\'-cytidylate + 7,8-dihydrofolate.','2013-10-27','NSRP'),(25825,50004,'isoflavone 7-O-glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.','2013-10-27','NSRP'),(25826,50005,'isohexenylglutaconyl-CoA hydratase activity','F','Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O.','2013-10-27','NSRP'),(25827,50006,'isomaltulose synthase activity','F','Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.','2013-10-27','NSRP'),(25828,50007,'isonocardicin synthase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5\'-thioadenosine + H(+) + isonocardicin A.','2013-10-27','NSRP'),(25829,50008,'isopiperitenone delta-isomerase activity','F','Catalysis of the reaction: isopiperitenone = piperitenone.','2013-10-27','NSRP'),(25830,50009,'isopropanol dehydrogenase (NADP+) activity','F','Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH.','2013-10-27','NSRP'),(25831,50010,'isovitexin beta-glucosyltransferase activity','F','Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2\'\'-O-beta-D-glucoside + UDP.','2013-10-27','NSRP'),(25832,50011,'itaconyl-CoA hydratase activity','F','Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.','2013-10-27','NSRP'),(25833,50012,'juglone 3-monooxygenase activity','F','Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-naphthoquinone + A + H(2)O + H(+).','2013-10-27','NSRP'),(25834,50013,'2-dehydropantoate aldolase activity','F','Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.','2013-10-27','NSRP'),(25835,50014,'ketotetrose-phosphate aldolase activity','F','Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.','2013-10-27','NSRP'),(25836,50015,'kievitone hydratase activity','F','Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone.','2013-10-27','NSRP'),(25837,50016,'kynurenine 7,8-hydroxylase activity','F','Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.','2013-10-27','NSRP'),(25838,50017,'L-3-cyanoalanine synthase activity','F','Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.','2013-10-27','NSRP'),(25839,50018,'L-amino-acid dehydrogenase activity','F','Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.','2013-10-27','NSRP'),(25840,50019,'L-arabinitol 4-dehydrogenase activity','F','Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH.','2013-10-27','NSRP'),(25841,50020,'L-arabinonate dehydratase activity','F','Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.','2013-10-27','NSRP'),(25842,50021,'L-arabinonolactonase activity','F','Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+).','2013-10-27','NSRP'),(25843,50022,'L-arabinose 1-dehydrogenase (NAD+) activity','F','Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.','2013-10-27','NSRP'),(25844,50023,'L-fuconate dehydratase activity','F','Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O.','2013-10-27','NSRP'),(25845,50024,'L-galactonolactone oxidase activity','F','Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+).','2013-10-27','NSRP'),(25846,50025,'L-glutamate oxidase activity','F','Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.','2013-10-27','NSRP'),(25847,50026,'L-glycol dehydrogenase activity','F','Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.','2013-10-27','NSRP'),(25848,50027,'L-idonate 2-dehydrogenase activity','F','OBSOLETE. Catalysis of the reaction: L-idonate + NADP+ = 5-dehydro-D-gluconate + NADPH.','2013-10-27','NSRP'),(25849,50028,'L-lysine-lactamase activity','F','Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine.','2013-10-27','NSRP'),(25850,50029,'L-lysine oxidase activity','F','Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+).','2013-10-27','NSRP'),(25851,50030,'L-pipecolate dehydrogenase activity','F','Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.','2013-10-27','NSRP'),(25852,50031,'L-pipecolate oxidase activity','F','Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.','2013-10-27','NSRP'),(25853,50032,'L-rhamnonate dehydratase activity','F','Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O.','2013-10-27','NSRP'),(25854,50033,'L-rhamnono-1,4-lactonase activity','F','Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+).','2013-10-27','NSRP'),(25855,50034,'L-rhamnose 1-dehydrogenase activity','F','Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH.','2013-10-27','NSRP'),(25856,50035,'L-sorbose oxidase activity','F','Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2).','2013-10-27','NSRP'),(25857,50036,'L-threonate 3-dehydrogenase activity','F','Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH.','2013-10-27','NSRP'),(25858,50037,'L-xylose 1-dehydrogenase activity','F','Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH.','2013-10-27','NSRP'),(25859,50038,'L-xylulose reductase (NADP+) activity','F','Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.','2013-10-27','NSRP'),(25860,50039,'lactaldehyde reductase (NADPH) activity','F','Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH.','2013-10-27','NSRP'),(25861,50040,'lactate 2-monooxygenase activity','F','Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O.','2013-10-27','NSRP'),(25862,50041,'lactate aldolase activity','F','Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.','2013-10-27','NSRP'),(25863,50042,'lactate-malate transhydrogenase activity','F','Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.','2013-10-27','NSRP'),(25864,50043,'lactate racemase activity','F','Catalysis of the reaction: (S)-lactate = (R)-lactate.','2013-10-27','NSRP'),(25865,50044,'galactose-6-phosphate isomerase activity','F','Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.','2013-10-27','NSRP'),(25866,50045,'laminaribiose phosphorylase activity','F','Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.','2013-10-27','NSRP'),(25867,50046,'lathosterol oxidase activity','F','Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2.','2013-10-27','NSRP'),(25868,50047,'leucine 2,3-aminomutase activity','F','Catalysis of the reaction: L-leucine = (3R)-beta-leucine.','2013-10-27','NSRP'),(25869,50048,'L-leucine:2-oxoglutarate aminotransferase activity','F','Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.','2013-10-27','NSRP'),(25870,50049,'leucine dehydrogenase activity','F','Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH.','2013-10-27','NSRP'),(25871,50050,'leucine N-acetyltransferase activity','F','Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+).','2013-10-27','NSRP'),(25872,50051,'leukotriene-B4 20-monooxygenase activity','F','Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O.','2013-10-27','NSRP'),(25873,50052,'leukotriene-E4 20-monooxygenase activity','F','Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+).','2013-10-27','NSRP'),(25874,50053,'levansucrase activity','F','Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).','2013-10-27','NSRP'),(25875,50054,'lignostilbene alpha beta-dioxygenase activity','F','Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin.','2013-10-27','NSRP'),(25876,50055,'limonin-D-ring-lactonase activity','F','Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.','2013-10-27','NSRP'),(25877,50056,'linalool 8-monooxygenase activity','F','Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O.','2013-10-27','NSRP'),(25878,50057,'linamarin synthase activity','F','Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.','2013-10-27','NSRP'),(25879,50058,'linoleate isomerase activity','F','Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.','2013-10-27','NSRP'),(25880,50059,'lombricine kinase activity','F','Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.','2013-10-27','NSRP'),(25881,50060,'long-chain-alcohol dehydrogenase activity','F','Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.','2013-10-27','NSRP'),(25882,50061,'long-chain-aldehyde dehydrogenase activity','F','Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.','2013-10-27','NSRP'),(25883,50062,'long-chain-fatty-acyl-CoA reductase activity','F','Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.','2013-10-27','NSRP'),(25884,50063,'low-density-lipoprotein particle receptor kinase activity','F','Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine.','2013-10-27','NSRP'),(25885,50064,'luteolin 7-O-glucuronosyltransferase activity','F','Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.','2013-10-27','NSRP'),(25886,50065,'lysine-pyruvate 6-transaminase activity','F','Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine.','2013-10-27','NSRP'),(25887,50066,'lysine 2,3-aminomutase activity','F','Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.','2013-10-27','NSRP'),(25888,50067,'lysine 2-monooxygenase activity','F','Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O.','2013-10-27','NSRP'),(25889,50068,'lysine carbamoyltransferase activity','F','Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate.','2013-10-27','NSRP'),(25890,50069,'lysine dehydrogenase activity','F','Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH.','2013-10-27','NSRP'),(25891,50070,'lysolecithin acylmutase activity','F','Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.','2013-10-27','NSRP'),(25892,50071,'lysyltransferase activity','F','Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1\'-(3\'-O-L-lysyl)glycerol.','2013-10-27','NSRP'),(25893,50072,'m7G(5\')pppN diphosphatase activity','F','Catalysis of the reaction: 7-methylguanosine 5\'-triphospho-5\'-polynucleotide + H2O = 7-methylguanosine 5\'-phosphate + polynucleotide.','2013-10-27','NSRP'),(25894,50073,'macrolide 2\'-kinase activity','F','Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2\'-O-phosphate.','2013-10-27','NSRP'),(25895,50074,'malate-CoA ligase activity','F','Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.','2013-10-27','NSRP'),(25896,50075,'maleate hydratase activity','F','Catalysis of the reaction: (R)-malate = H(2)O + maleate.','2013-10-27','NSRP'),(25897,50076,'maleate isomerase activity','F','Catalysis of the reaction: maleate = fumarate.','2013-10-27','NSRP'),(25898,50077,'maleylpyruvate isomerase activity','F','Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.','2013-10-27','NSRP'),(25899,50078,'malonate CoA-transferase activity','F','Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.','2013-10-27','NSRP'),(25900,50079,'acetylenecarboxylate hydratase activity, producing 3-oxopropanoate','F','Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.','2013-10-27','NSRP'),(25901,50080,'malonyl-CoA decarboxylase activity','F','Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.','2013-10-27','NSRP'),(25902,50081,'maltose-6\'-phosphate glucosidase activity','F','Catalysis of the reaction: H2O + maltose 6\'-phosphate = D-glucose + D-glucose 6-phosphate.','2013-10-27','NSRP'),(25903,50082,'maltose phosphorylase activity','F','Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.','2013-10-27','NSRP'),(25904,50083,'malyl-CoA lyase activity','F','Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.','2013-10-27','NSRP'),(25905,50084,'mannitol-1-phosphatase activity','F','Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.','2013-10-27','NSRP'),(25906,50085,'mannitol 2-dehydrogenase (NADP+) activity','F','Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH.','2013-10-27','NSRP'),(25907,50086,'mannitol 2-dehydrogenase activity','F','Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.','2013-10-27','NSRP'),(25908,50087,'mannitol dehydrogenase (cytochrome) activity','F','Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c.','2013-10-27','NSRP'),(25909,50088,'mannose-6-phosphate 6-reductase activity','F','Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH.','2013-10-27','NSRP'),(25910,50089,'mannose isomerase activity','F','Catalysis of the reaction: D-mannose = D-fructose.','2013-10-27','NSRP'),(25911,50090,'mannuronate reductase activity','F','Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.','2013-10-27','NSRP'),(25912,50091,'melilotate 3-monooxygenase activity','F','Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+).','2013-10-27','NSRP'),(25913,50092,'meso-tartrate dehydrogenase activity','F','Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH.','2013-10-27','NSRP'),(25914,50093,'methanol dehydrogenase activity','F','Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH.','2013-10-27','NSRP'),(25915,50094,'methionine-glyoxylate transaminase activity','F','Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.','2013-10-27','NSRP'),(25916,50095,'methionine decarboxylase activity','F','Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2).','2013-10-27','NSRP'),(25917,50096,'methylaspartate ammonia-lyase activity','F','Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+).','2013-10-27','NSRP'),(25918,50097,'methylaspartate mutase activity','F','Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.','2013-10-27','NSRP'),(25919,50098,'methylguanidinase activity','F','Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea.','2013-10-27','NSRP'),(25920,50099,'methylglutamate dehydrogenase activity','F','Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde.','2013-10-27','NSRP'),(25921,50100,'methylitaconate delta-isomerase activity','F','Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.','2013-10-27','NSRP'),(25922,50101,'mimosinase activity','F','Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine.','2013-10-27','NSRP'),(25923,50102,'cellodextrin phosphorylase activity','F','Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.','2013-10-27','NSRP'),(25924,50103,'dextrin dextranase activity','F','Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).','2013-10-27','NSRP'),(25925,50104,'L-gulonate 3-dehydrogenase activity','F','Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.','2013-10-27','NSRP'),(25926,50105,'L-gulonolactone oxidase activity','F','Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.','2013-10-27','NSRP'),(25927,50106,'monomethyl-sulfatase activity','F','Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate.','2013-10-27','NSRP'),(25928,50107,'monoterpenol O-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.','2013-10-27','NSRP'),(25929,50108,'monoterpenyl-diphosphatase activity','F','Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.','2013-10-27','NSRP'),(25930,50109,'morphine 6-dehydrogenase activity','F','Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.','2013-10-27','NSRP'),(25931,50110,'mucinaminylserine mucinaminidase activity','F','Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.','2013-10-27','NSRP'),(25932,50111,'mycocerosate synthase activity','F','Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+).','2013-10-27','NSRP'),(25933,50112,'inositol 2-dehydrogenase activity','F','Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH.','2013-10-27','NSRP'),(25934,50113,'inositol oxygenase activity','F','Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+).','2013-10-27','NSRP'),(25935,50114,'myo-inosose-2 dehydratase activity','F','Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O.','2013-10-27','NSRP'),(25936,50115,'myosin-light-chain-phosphatase activity','F','Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.','2013-10-27','NSRP'),(25937,50116,'N,N-dimethylformamidase activity','F','Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate.','2013-10-27','NSRP'),(25938,50117,'N-acetyl-beta-alanine deacetylase activity','F','Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate.','2013-10-27','NSRP'),(25939,50118,'N-acetyldiaminopimelate deacetylase activity','F','Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate.','2013-10-27','NSRP'),(25940,50119,'N-acetylglucosamine deacetylase activity','F','Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate.','2013-10-27','NSRP'),(25941,50120,'N-acetylhexosamine 1-dehydrogenase activity','F','Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH.','2013-10-27','NSRP'),(25942,50121,'N-acylglucosamine 2-epimerase activity','F','Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.','2013-10-27','NSRP'),(25943,50122,'N-acylhexosamine oxidase activity','F','Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+).','2013-10-27','NSRP'),(25944,50123,'N-acylmannosamine 1-dehydrogenase activity','F','Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH.','2013-10-27','NSRP'),(25945,50124,'N-acylneuraminate-9-phosphatase activity','F','Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.','2013-10-27','NSRP'),(25946,50125,'N-benzyloxycarbonylglycine hydrolase activity','F','Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine.','2013-10-27','NSRP'),(25947,50126,'N-carbamoylputrescine amidase activity','F','Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine.','2013-10-27','NSRP'),(25948,50127,'N-carbamoylsarcosine amidase activity','F','Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine.','2013-10-27','NSRP'),(25949,50128,'N-feruloylglycine deacylase activity','F','Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine.','2013-10-27','NSRP'),(25950,50129,'N-formylglutamate deformylase activity','F','Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.','2013-10-27','NSRP'),(25951,50130,'N-methyl-2-oxoglutaramate hydrolase activity','F','Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium.','2013-10-27','NSRP'),(25952,50131,'N-methyl-L-amino-acid oxidase activity','F','Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.','2013-10-27','NSRP'),(25953,50132,'N-methylalanine dehydrogenase activity','F','Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate.','2013-10-27','NSRP'),(25954,50133,'N6-hydroxylysine O-acetyltransferase activity','F','Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.','2013-10-27','NSRP'),(25955,50134,'N6-methyl-lysine oxidase activity','F','Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2).','2013-10-27','NSRP'),(25956,50135,'NAD(P)+ nucleosidase activity','F','Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide.','2013-10-27','NSRP'),(25957,50136,'NADH dehydrogenase (quinone) activity','F','Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.','2013-10-27','NSRP'),(25958,50137,'NADPH peroxidase activity','F','Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+).','2013-10-27','NSRP'),(25959,50138,'nicotinate dehydrogenase activity','F','Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH.','2013-10-27','NSRP'),(25960,50139,'nicotinate glucosyltransferase activity','F','Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.','2013-10-27','NSRP'),(25961,50140,'nitrate reductase (cytochrome) activity','F','Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.','2013-10-27','NSRP'),(25962,50141,'nitroethane oxidase activity','F','Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2.','2013-10-27','NSRP'),(25963,50142,'nitrogenase (flavodoxin) activity','F','Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.','2013-10-27','NSRP'),(25964,50143,'nocardicin-A epimerase activity','F','Catalysis of the reaction: isonocardicin A = nocardicin A.','2013-10-27','NSRP'),(25965,50144,'nucleoside deoxyribosyltransferase activity','F','Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.','2013-10-27','NSRP'),(25966,50145,'nucleoside phosphate kinase activity','F','Catalysis of the reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate.','2013-10-27','NSRP'),(25967,50146,'nucleoside phosphotransferase activity','F','Catalysis of the reaction: a nucleotide + a 2\'-deoxynucleoside = a nucleoside + a 2\'-deoxynucleoside 5\'-monophosphate.','2013-10-27','NSRP'),(25968,50147,'nucleoside ribosyltransferase activity','F','Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.','2013-10-27','NSRP'),(25969,50148,'nucleotide diphosphokinase activity','F','Catalysis of the reaction: ATP + nucleoside 5\'-phosphate = AMP + 5\'-phosphonucleoside 3\'-diphosphate.','2013-10-27','NSRP'),(25970,50149,'o-aminophenol oxidase activity','F','Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.','2013-10-27','NSRP'),(25971,50150,'o-pyrocatechuate decarboxylase activity','F','Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2).','2013-10-27','NSRP'),(25972,50151,'oleate hydratase activity','F','Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate.','2013-10-27','NSRP'),(25973,50152,'omega-amidase activity','F','Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.','2013-10-27','NSRP'),(25974,50153,'omega-hydroxydecanoate dehydrogenase activity','F','Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH.','2013-10-27','NSRP'),(25975,50154,'opheline kinase activity','F','Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N\'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(25976,50155,'ornithine(lysine) transaminase activity','F','Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate.','2013-10-27','NSRP'),(25977,50156,'ornithine N-benzoyltransferase activity','F','Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+).','2013-10-27','NSRP'),(25978,50157,'ornithine racemase activity','F','Catalysis of the reaction: L-ornithine = D-ornithine.','2013-10-27','NSRP'),(25979,50158,'orotate reductase (NADPH) activity','F','Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate.','2013-10-27','NSRP'),(25980,50159,'orsellinate decarboxylase activity','F','Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol.','2013-10-27','NSRP'),(25981,50160,'orsellinate-depside hydrolase activity','F','Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+).','2013-10-27','NSRP'),(25982,50161,'succinyl-CoA:oxalate CoA-transferase','F','Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.','2013-10-27','NSRP'),(25983,50162,'oxalate oxidase activity','F','Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2).','2013-10-27','NSRP'),(25984,50163,'oxaloacetate tautomerase activity','F','Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.','2013-10-27','NSRP'),(25985,50164,'oxoglutarate dehydrogenase (NADP+) activity','F','Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA.','2013-10-27','NSRP'),(25986,50165,'pantetheine kinase activity','F','Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4\'-phosphate.','2013-10-27','NSRP'),(25987,50166,'pantoate 4-dehydrogenase activity','F','Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH.','2013-10-27','NSRP'),(25988,50167,'pantothenoylcysteine decarboxylase activity','F','Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2).','2013-10-27','NSRP'),(25989,50168,'pentanamidase activity','F','Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate.','2013-10-27','NSRP'),(25990,50169,'peptide-tryptophan 2,3-dioxygenase activity','F','Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine.','2013-10-27','NSRP'),(25991,50170,'peptidyl-glutaminase activity','F','Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.','2013-10-27','NSRP'),(25992,50171,'phenol beta-glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.','2013-10-27','NSRP'),(25993,50172,'phenylalanine 2-monooxygenase activity','F','Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O.','2013-10-27','NSRP'),(25994,50173,'phenylalanine adenylyltransferase activity','F','Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+).','2013-10-27','NSRP'),(25995,50174,'phenylalanine decarboxylase activity','F','Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.','2013-10-27','NSRP'),(25996,50175,'phenylalanine dehydrogenase activity','F','Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH.','2013-10-27','NSRP'),(25997,50176,'phenylalanine N-acetyltransferase activity','F','Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+).','2013-10-27','NSRP'),(25998,50177,'phenylpyruvate decarboxylase activity','F','Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.','2013-10-27','NSRP'),(25999,50178,'phenylpyruvate tautomerase activity','F','Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.','2013-10-27','NSRP'),(26000,50179,'phenylserine aldolase activity','F','Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.','2013-10-27','NSRP'),(26001,50180,'phloretin hydrolase activity','F','Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol.','2013-10-27','NSRP'),(26002,50181,'phorbol-diester hydrolase activity','F','Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate.','2013-10-27','NSRP'),(26003,50182,'phosphate butyryltransferase activity','F','Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.','2013-10-27','NSRP'),(26004,50183,'phosphatidylcholine 12-monooxygenase activity','F','Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+).','2013-10-27','NSRP'),(26005,50184,'phosphatidylcholine desaturase activity','F','Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH.','2013-10-27','NSRP'),(26006,50185,'phosphatidylinositol deacylase activity','F','Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+).','2013-10-27','NSRP'),(26007,50186,'phosphoadenylylsulfatase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + H2O = adenosine 3\',5\'-bisphosphate + sulfate.','2013-10-27','NSRP'),(26008,50187,'phosphoamidase activity','F','Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate.','2013-10-27','NSRP'),(26009,50188,'phosphoenolpyruvate mutase activity','F','Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.','2013-10-27','NSRP'),(26010,50189,'phosphoenolpyruvate phosphatase activity','F','Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate.','2013-10-27','NSRP'),(26011,50190,'phosphoglucokinase activity','F','Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26012,50191,'phosphoglycerate kinase (GTP) activity','F','Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+).','2013-10-27','NSRP'),(26013,50192,'phosphoglycerate phosphatase activity','F','Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.','2013-10-27','NSRP'),(26014,50193,'phosphoketolase activity','F','Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.','2013-10-27','NSRP'),(26015,50194,'phosphonoacetaldehyde hydrolase activity','F','Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate.','2013-10-27','NSRP'),(26016,50195,'phosphoribokinase activity','F','Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26017,50196,'[phosphorylase] phosphatase activity','F','Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.','2013-10-27','NSRP'),(26018,50197,'phytanate-CoA ligase activity','F','Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA.','2013-10-27','NSRP'),(26019,50198,'pinosylvin synthase activity','F','Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin.','2013-10-27','NSRP'),(26020,50199,'piperidine N-piperoyltransferase activity','F','Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+).','2013-10-27','NSRP'),(26021,50200,'plasmalogen synthase activity','F','Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.','2013-10-27','NSRP'),(26022,50201,'fucokinase activity','F','Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26023,50202,'octopamine dehydratase activity','F','Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+).','2013-10-27','NSRP'),(26024,50203,'oxalate-CoA ligase activity','F','Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.','2013-10-27','NSRP'),(26025,50204,'oxalomalate lyase activity','F','Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.','2013-10-27','NSRP'),(26026,50205,'oxamate carbamoyltransferase activity','F','Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.','2013-10-27','NSRP'),(26027,50206,'oximinotransferase activity','F','Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.','2013-10-27','NSRP'),(26028,50207,'plasmanylethanolamine desaturase activity','F','Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O.','2013-10-27','NSRP'),(26029,50208,'polysialic-acid O-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.','2013-10-27','NSRP'),(26030,50209,'polyvinyl-alcohol oxidase activity','F','Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.','2013-10-27','NSRP'),(26031,50210,'prenyl-diphosphatase activity','F','Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.','2013-10-27','NSRP'),(26032,50211,'procollagen galactosyltransferase activity','F','Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.','2013-10-27','NSRP'),(26033,50212,'progesterone 11-alpha-monooxygenase activity','F','Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O.','2013-10-27','NSRP'),(26034,50213,'progesterone 5-alpha-reductase activity','F','Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH.','2013-10-27','NSRP'),(26035,50214,'progesterone monooxygenase activity','F','Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate.','2013-10-27','NSRP'),(26036,50215,'propanediol dehydratase activity','F','Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal.','2013-10-27','NSRP'),(26037,50216,'propanediol-phosphate dehydrogenase activity','F','Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH.','2013-10-27','NSRP'),(26038,50217,'propioin synthase activity','F','Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.','2013-10-27','NSRP'),(26039,50218,'propionate-CoA ligase activity','F','Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.','2013-10-27','NSRP'),(26040,50219,'prostaglandin-A1 delta-isomerase activity','F','Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.','2013-10-27','NSRP'),(26041,50220,'prostaglandin-E synthase activity','F','Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).','2013-10-27','NSRP'),(26042,50221,'prostaglandin-E2 9-reductase activity','F','Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.','2013-10-27','NSRP'),(26043,50223,'protocatechuate decarboxylase activity','F','Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2).','2013-10-27','NSRP'),(26044,50224,'prunasin beta-glucosidase activity','F','Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile.','2013-10-27','NSRP'),(26045,50225,'pseudouridine kinase activity','F','Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5\'-phosphate.','2013-10-27','NSRP'),(26046,50226,'psychosine sulfotransferase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + galactosylsphingosine = adenosine 3\',5\'-bisphosphate + psychosine sulfate.','2013-10-27','NSRP'),(26047,50227,'pteridine oxidase activity','F','Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.','2013-10-27','NSRP'),(26048,50228,'pterin deaminase activity','F','Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3.','2013-10-27','NSRP'),(26049,50229,'pterocarpin synthase activity','F','Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH.','2013-10-27','NSRP'),(26050,50230,'purine imidazole-ring cyclase activity','F','Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.','2013-10-27','NSRP'),(26051,50231,'putrescine carbamoyltransferase activity','F','Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate.','2013-10-27','NSRP'),(26052,50232,'putrescine oxidase activity','F','Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.','2013-10-27','NSRP'),(26053,50233,'pyranose oxidase activity','F','Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2).','2013-10-27','NSRP'),(26054,50234,'pyrazolylalanine synthase activity','F','Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O.','2013-10-27','NSRP'),(26055,50235,'pyridoxal 4-dehydrogenase activity','F','Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH.','2013-10-27','NSRP'),(26056,50236,'pyridoxine:NADP 4-dehydrogenase activity','F','Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal.','2013-10-27','NSRP'),(26057,50237,'pyridoxine 4-oxidase activity','F','Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.','2013-10-27','NSRP'),(26058,50238,'pyridoxine 5-dehydrogenase activity','F','Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.','2013-10-27','NSRP'),(26059,50239,'pyrithiamine deaminase activity','F','Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.','2013-10-27','NSRP'),(26060,50240,'pyrogallol 1,2-oxygenase activity','F','Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+).','2013-10-27','NSRP'),(26061,50241,'pyrroline-2-carboxylate reductase activity','F','Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.','2013-10-27','NSRP'),(26062,50242,'pyruvate, phosphate dikinase activity','F','Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.','2013-10-27','NSRP'),(26063,50243,'pyruvate dehydrogenase (NADP+) activity','F','Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH.','2013-10-27','NSRP'),(26064,50244,'pyruvate oxidase (CoA-acetylating) activity','F','Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2).','2013-10-27','NSRP'),(26065,50245,'quercitrinase activity','F','Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin.','2013-10-27','NSRP'),(26066,50246,'questin monooxygenase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+).','2013-10-27','NSRP'),(26067,50247,'raucaffricine beta-glucosidase activity','F','Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine.','2013-10-27','NSRP'),(26068,50248,'Renilla-luciferin 2-monooxygenase activity','F','Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.','2013-10-27','NSRP'),(26069,50249,'Renilla-luciferin sulfotransferase activity','F','Catalysis of the reaction: 3\'-phospho-5\'-adenylyl sulfate + Renilla luciferin = adenosine 3\',5\'-diphosphate + H(+) + luciferyl sulfate.','2013-10-27','NSRP'),(26070,50250,'retinal oxidase activity','F','Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2.','2013-10-27','NSRP'),(26071,50251,'retinol isomerase activity','F','Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.','2013-10-27','NSRP'),(26072,50252,'retinol O-fatty-acyltransferase activity','F','Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.','2013-10-27','NSRP'),(26073,50253,'retinyl-palmitate esterase activity','F','Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.','2013-10-27','NSRP'),(26074,50254,'rhodopsin kinase activity','F','Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.','2013-10-27','NSRP'),(26075,50255,'ribitol 2-dehydrogenase activity','F','Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH.','2013-10-27','NSRP'),(26076,50256,'ribitol-5-phosphate 2-dehydrogenase activity','F','Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.','2013-10-27','NSRP'),(26077,50257,'riboflavin phosphotransferase activity','F','Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.','2013-10-27','NSRP'),(26078,50258,'riboflavinase activity','F','Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome.','2013-10-27','NSRP'),(26079,50259,'ribose 1-dehydrogenase (NADP+) activity','F','Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH.','2013-10-27','NSRP'),(26080,50260,'ribose-5-phosphate-ammonia ligase activity','F','Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate.','2013-10-27','NSRP'),(26081,50261,'ribose isomerase activity','F','Catalysis of the reaction: ribofuranose = D-ribulose.','2013-10-27','NSRP'),(26082,50262,'ribosylnicotinamide kinase activity','F','Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide.','2013-10-27','NSRP'),(26083,50263,'ribosylpyrimidine nucleosidase activity','F','Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.','2013-10-27','NSRP'),(26084,50264,'rifamycin-B oxidase activity','F','Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O.','2013-10-27','NSRP'),(26085,50265,'RNA uridylyltransferase activity','F','Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).','2013-10-27','NSRP'),(26086,50266,'rosmarinate synthase activity','F','Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.','2013-10-27','NSRP'),(26087,50267,'rubber cis-polyprenylcistransferase activity','F','Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.','2013-10-27','NSRP'),(26088,50268,'coniferyl-alcohol dehydrogenase activity','F','Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.','2013-10-27','NSRP'),(26089,50269,'coniferyl-aldehyde dehydrogenase activity','F','Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.','2013-10-27','NSRP'),(26090,50270,'S-adenosylhomocysteine deaminase activity','F','Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+).','2013-10-27','NSRP'),(26091,50271,'S-alkylcysteine lyase activity','F','Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.','2013-10-27','NSRP'),(26092,50272,'S-carboxymethylcysteine synthase activity','F','Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+).','2013-10-27','NSRP'),(26093,50273,'S-succinylglutathione hydrolase activity','F','Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate.','2013-10-27','NSRP'),(26094,50274,'salicyl-alcohol beta-D-glucosyltransferase activity','F','Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP.','2013-10-27','NSRP'),(26095,50275,'scopoletin glucosyltransferase activity','F','Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP.','2013-10-27','NSRP'),(26096,50276,'scyllo-inosamine 4-kinase activity','F','Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26097,50277,'sedoheptulokinase activity','F','Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate.','2013-10-27','NSRP'),(26098,50278,'sedoheptulose-bisphosphatase activity','F','Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.','2013-10-27','NSRP'),(26099,50279,'sepiapterin deaminase activity','F','Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.','2013-10-27','NSRP'),(26100,50280,'sequoyitol dehydrogenase activity','F','Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH.','2013-10-27','NSRP'),(26101,50281,'serine-glyoxylate transaminase activity','F','Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.','2013-10-27','NSRP'),(26102,50282,'serine 2-dehydrogenase activity','F','Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.','2013-10-27','NSRP'),(26103,50283,'serine-sulfate ammonia-lyase activity','F','Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate.','2013-10-27','NSRP'),(26104,50284,'sinapate 1-glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.','2013-10-27','NSRP'),(26105,50285,'sinapine esterase activity','F','Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate.','2013-10-27','NSRP'),(26106,50286,'sorbitol-6-phosphatase activity','F','Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.','2013-10-27','NSRP'),(26107,50287,'sorbose 5-dehydrogenase (NADP+) activity','F','Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH.','2013-10-27','NSRP'),(26108,50288,'sorbose dehydrogenase activity','F','Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).','2013-10-27','NSRP'),(26109,50289,'spermidine dehydrogenase activity','F','Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.','2013-10-27','NSRP'),(26110,50290,'sphingomyelin phosphodiesterase D activity','F','Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+).','2013-10-27','NSRP'),(26111,50291,'sphingosine N-acyltransferase activity','F','Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.','2013-10-27','NSRP'),(26112,50292,'steroid 9-alpha-monooxygenase activity','F','Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O.','2013-10-27','NSRP'),(26113,50293,'steroid-lactonase activity','F','Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate.','2013-10-27','NSRP'),(26114,50294,'steroid sulfotransferase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + a phenolic steroid = adenosine 3\',5\'-bisphosphate + steroid O-sulfate.','2013-10-27','NSRP'),(26115,50295,'steryl-beta-glucosidase activity','F','Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol.','2013-10-27','NSRP'),(26116,50296,'stipitatonate decarboxylase activity','F','Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate.','2013-10-27','NSRP'),(26117,50297,'stizolobate synthase activity','F','Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.','2013-10-27','NSRP'),(26118,50298,'stizolobinate synthase activity','F','Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.','2013-10-27','NSRP'),(26119,50299,'streptomycin 3\'\'-kinase activity','F','Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3\'\'-phosphate.','2013-10-27','NSRP'),(26120,50300,'aminoglycoside 6-kinase activity','F','Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate.','2013-10-27','NSRP'),(26121,50301,'streptomycin-6-phosphatase activity','F','Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin.','2013-10-27','NSRP'),(26122,50302,'indole-3-acetaldehyde oxidase activity','F','Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).','2013-10-27','NSRP'),(26123,50303,'lysine 6-dehydrogenase activity','F','Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine.','2013-10-27','NSRP'),(26124,50304,'nitrous-oxide reductase activity','F','Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.','2013-10-27','NSRP'),(26125,50305,'strombine dehydrogenase activity','F','Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate.','2013-10-27','NSRP'),(26126,50306,'sucrose 1F-fructosyltransferase activity','F','Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.','2013-10-27','NSRP'),(26127,50307,'sucrose-phosphate phosphatase activity','F','Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.','2013-10-27','NSRP'),(26128,50308,'sugar-phosphatase activity','F','Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.','2013-10-27','NSRP'),(26129,50309,'sugar-terminal-phosphatase activity','F','Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.','2013-10-27','NSRP'),(26130,50310,'sulfite dehydrogenase activity','F','Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.','2013-10-27','NSRP'),(26131,50311,'sulfite reductase (ferredoxin) activity','F','Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.','2013-10-27','NSRP'),(26132,50312,'sulfoacetaldehyde lyase activity','F','Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.','2013-10-27','NSRP'),(26133,50313,'sulfur dioxygenase activity','F','Catalysis of the reaction: sulfur + O2 + H2O = sulfite.','2013-10-27','NSRP'),(26134,50314,'sym-norspermidine synthase activity','F','Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5\'-thioadenosine + bis(3-aminopropyl)amine + H(+).','2013-10-27','NSRP'),(26135,50315,'synephrine dehydratase activity','F','Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.','2013-10-27','NSRP'),(26136,50316,'T2-induced deoxynucleotide kinase activity','F','Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP.','2013-10-27','NSRP'),(26137,50317,'tagatose kinase activity','F','Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26138,50318,'tannase activity','F','Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+).','2013-10-27','NSRP'),(26139,50319,'tartrate decarboxylase activity','F','Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2).','2013-10-27','NSRP'),(26140,50320,'tartrate epimerase activity','F','Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.','2013-10-27','NSRP'),(26141,50321,'tau-protein kinase activity','F','Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.','2013-10-27','NSRP'),(26142,50322,'taurine-2-oxoglutarate transaminase activity','F','Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.','2013-10-27','NSRP'),(26143,50323,'taurine dehydrogenase activity','F','Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde.','2013-10-27','NSRP'),(26144,50324,'taurocyamine kinase activity','F','Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+).','2013-10-27','NSRP'),(26145,50325,'tauropine dehydrogenase activity','F','Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine.','2013-10-27','NSRP'),(26146,50326,'taxifolin 8-monooxygenase activity','F','Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.','2013-10-27','NSRP'),(26147,50327,'testosterone 17-beta-dehydrogenase (NAD+) activity','F','Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.','2013-09-29','NSRP'),(26148,50328,'tetrahydroberberine oxidase activity','F','Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.','2013-10-27','NSRP'),(26149,50329,'tetrahydroxypteridine cycloisomerase activity','F','Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate.','2013-10-27','NSRP'),(26150,50330,'theanine hydrolase activity','F','Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine.','2013-10-27','NSRP'),(26151,50331,'thiamine-diphosphate kinase activity','F','Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.','2013-10-27','NSRP'),(26152,50332,'thiamine pyridinylase activity','F','Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.','2013-10-27','NSRP'),(26153,50333,'thiamin-triphosphatase activity','F','Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.','2013-10-27','NSRP'),(26154,50334,'thiaminase activity','F','Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+).','2013-10-27','NSRP'),(26155,50335,'thiocyanate isomerase activity','F','Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.','2013-10-27','NSRP'),(26156,50336,'thioethanolamine S-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.','2013-10-27','NSRP'),(26157,50337,'thiosulfate-thiol sulfurtransferase activity','F','Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.','2013-10-27','NSRP'),(26158,50338,'thiosulfate dehydrogenase activity','F','Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.','2013-10-27','NSRP'),(26159,50339,'thymidine-triphosphatase activity','F','Catalysis of the reaction: dTTP + H2O = dTDP + phosphate.','2013-10-27','NSRP'),(26160,50340,'thymidylate 5\'-phosphatase activity','F','Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.','2013-10-27','NSRP'),(26161,50341,'thymine dioxygenase activity','F','Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.','2013-10-27','NSRP'),(26162,50342,'tocopherol O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.','2013-10-27','NSRP'),(26163,50343,'trans-2-enoyl-CoA reductase (NAD+) activity','F','Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.','2013-10-27','NSRP'),(26164,50344,'trans-cinnamate 2-monooxygenase activity','F','Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+).','2013-10-27','NSRP'),(26165,50345,'trans-epoxysuccinate hydrolase activity','F','Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate.','2013-10-27','NSRP'),(26166,50346,'trans-L-3-hydroxyproline dehydratase activity','F','Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+).','2013-10-27','NSRP'),(26167,50347,'trans-octaprenyltranstransferase activity','F','Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate.','2013-10-27','NSRP'),(26168,50348,'trehalose O-mycolyltransferase activity','F','Catalysis of the reaction: 2 alpha,alpha\'-trehalose 6-mycolate = alpha,alpha\'-trehalose 6,6\'-bismycolate + alpha,alpha-trehalose.','2013-10-27','NSRP'),(26169,50349,'triacetate-lactonase activity','F','Catalysis of the reaction: H(2)O + triacetate lactone = triacetate.','2013-10-27','NSRP'),(26170,50350,'trihydroxystilbene synthase activity','F','Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4\',5-trihydroxy-stilbene + 4 CO2.','2013-10-27','NSRP'),(26171,50351,'trimetaphosphatase activity','F','Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate.','2013-10-27','NSRP'),(26172,50352,'trimethylamine-oxide aldolase activity','F','Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde.','2013-10-27','NSRP'),(26173,50353,'trimethyllysine dioxygenase activity','F','Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.','2013-10-27','NSRP'),(26174,50354,'triokinase activity','F','Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26175,50355,'triphosphatase activity','F','Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.','2013-10-27','NSRP'),(26176,50356,'tropine dehydrogenase activity','F','Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone.','2013-10-27','NSRP'),(26177,50357,'tropinesterase activity','F','Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine.','2013-10-27','NSRP'),(26178,50358,'tropinone reductase activity','F','Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone.','2013-10-27','NSRP'),(26179,50359,'tropomyosin kinase activity','F','Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.','2013-10-27','NSRP'),(26180,50360,'tryptophan 2\'-dioxygenase activity','F','Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.','2013-10-27','NSRP'),(26181,50361,'tryptophan 2-monooxygenase activity','F','Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide.','2013-10-27','NSRP'),(26182,50362,'L-tryptophan:2-oxoglutarate aminotransferase activity','F','Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate.','2013-10-27','NSRP'),(26183,50363,'tryptophan dehydrogenase activity','F','Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+.','2013-10-27','NSRP'),(26184,50364,'tryptophan dimethylallyltransferase activity','F','Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.','2013-10-27','NSRP'),(26185,50365,'tryptophanamidase activity','F','Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+).','2013-10-27','NSRP'),(26186,50366,'tyramine N-feruloyltransferase activity','F','Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.','2013-10-27','NSRP'),(26187,50367,'tyrosine-arginine ligase activity','F','Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+).','2013-10-27','NSRP'),(26188,50368,'tyrosine 2,3-aminomutase activity','F','Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.','2013-10-27','NSRP'),(26189,50369,'[tyrosine 3-monooxygenase] kinase activity','F','Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].','2013-10-27','NSRP'),(26190,50370,'tyrosine N-monooxygenase activity','F','Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.','2013-10-27','NSRP'),(26191,50371,'tyrosine phenol-lyase activity','F','Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate.','2013-10-27','NSRP'),(26192,50372,'ubiquitin-calmodulin ligase activity','F','Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin.','2013-10-27','NSRP'),(26193,50373,'UDP-arabinose 4-epimerase activity','F','Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.','2013-10-27','NSRP'),(26194,50374,'UDP-galacturonate decarboxylase activity','F','Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose.','2013-10-27','NSRP'),(26195,50376,'UDP-glucosamine 4-epimerase activity','F','Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.','2013-10-27','NSRP'),(26196,50377,'UDP-glucose 4,6-dehydratase activity','F','Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose.','2013-10-27','NSRP'),(26197,50378,'UDP-glucuronate 4-epimerase activity','F','Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.','2013-10-27','NSRP'),(26198,50379,'UDP-glucuronate 5\'-epimerase activity','F','Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.','2013-10-27','NSRP'),(26199,50380,'undecaprenyl-diphosphatase activity','F','Catalysis of the reaction: all-trans-undecaprenyl diphosphate + H(2)O = all-trans-undecaprenyl phosphate + H(+) + phosphate.','2013-10-27','NSRP'),(26200,50382,'uracil-5-carboxylate decarboxylase activity','F','Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil.','2013-10-27','NSRP'),(26201,50383,'uracil dehydrogenase activity','F','Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.','2013-10-27','NSRP'),(26202,50384,'urate-ribonucleotide phosphorylase activity','F','Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate.','2013-10-27','NSRP'),(26203,50385,'ureidoglycolate lyase activity','F','Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.','2013-10-27','NSRP'),(26204,50386,'ureidosuccinase activity','F','Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+).','2013-10-27','NSRP'),(26205,50387,'urethanase activity','F','Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+).','2013-10-27','NSRP'),(26206,50388,'uronate dehydrogenase activity','F','Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH.','2013-10-27','NSRP'),(26207,50389,'uronolactonase activity','F','Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.','2013-10-27','NSRP'),(26208,50390,'valine decarboxylase activity','F','Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2).','2013-10-27','NSRP'),(26209,50391,'valine dehydrogenase (NADP) activity','F','Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH.','2013-10-27','NSRP'),(26210,50392,'vicianin beta-glucosidase activity','F','Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose.','2013-10-27','NSRP'),(26211,50393,'vinylacetyl-CoA delta-isomerase activity','F','Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA.','2013-10-27','NSRP'),(26212,50394,'viomycin kinase activity','F','Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.','2013-10-27','NSRP'),(26213,50395,'vitexin beta-glucosyltransferase activity','F','Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2\'\'-O-beta-D-glucoside.','2013-10-27','NSRP'),(26214,50396,'vomifoliol 4\'-dehydrogenase activity','F','Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH.','2013-10-27','NSRP'),(26215,50397,'Watasenia-luciferin 2-monooxygenase activity','F','Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.','2013-10-27','NSRP'),(26216,50398,'wax-ester hydrolase activity','F','Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.','2013-10-27','NSRP'),(26217,50399,'xanthommatin reductase activity','F','Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin.','2013-10-27','NSRP'),(26218,50400,'xylitol kinase activity','F','Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate.','2013-10-27','NSRP'),(26219,50401,'xylonate dehydratase activity','F','Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.','2013-10-27','NSRP'),(26220,50402,'xylono-1,4-lactonase activity','F','Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.','2013-10-27','NSRP'),(26221,50403,'trans-zeatin O-beta-D-glucosyltransferase activity','F','Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP.','2013-10-27','NSRP'),(26222,50404,'zeatin O-beta-D-xylosyltransferase activity','F','Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP.','2013-10-27','NSRP'),(26223,50405,'[acetyl-CoA carboxylase] kinase activity','F','Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.','2013-10-27','NSRP'),(26224,50406,'[acetyl-CoA carboxylase]-phosphatase activity','F','Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.','2013-10-27','NSRP'),(26225,50407,'[glycogen-synthase-D] phosphatase activity','F','Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.','2013-10-27','NSRP'),(26226,50408,'[pyruvate kinase]-phosphatase activity','F','Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.','2013-10-27','NSRP'),(26227,50409,'indolylacetylinositol arabinosyltransferase activity','F','Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP.','2013-10-27','NSRP'),(26228,50410,'3-oxolaurate decarboxylase activity','F','Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2).','2013-10-27','NSRP'),(26229,50411,'agaritine gamma-glutamyltransferase activity','F','Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor.','2013-10-27','NSRP'),(26230,50412,'cinnamate beta-D-glucosyltransferase activity','F','Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.','2013-10-27','NSRP'),(26231,50413,'D-alanine 2-hydroxymethyltransferase activity','F','Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.','2013-10-27','NSRP'),(26232,50414,'formimidoylaspartate deiminase activity','F','Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.','2013-10-27','NSRP'),(26233,50415,'formimidoylglutamase activity','F','Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.','2013-10-27','NSRP'),(26234,50416,'formimidoylglutamate deiminase activity','F','Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3.','2013-10-27','NSRP'),(26235,50417,'glutamin-(asparagin-)ase activity','F','Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate.','2013-10-27','NSRP'),(26236,50418,'hydroxylamine reductase activity','F','Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.','2013-10-27','NSRP'),(26237,50419,'hydroxymandelonitrile lyase activity','F','Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.','2013-10-27','NSRP'),(26238,50420,'maltose synthase activity','F','Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.','2013-10-27','NSRP'),(26239,50421,'nitrite reductase (NO-forming) activity','F','Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.','2013-10-27','NSRP'),(26240,50422,'strictosidine beta-glucosidase activity','F','Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone.','2013-10-27','NSRP'),(26241,50423,'thiamine oxidase activity','F','Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.','2013-10-27','NSRP'),(26242,50424,'alanine carboxypeptidase activity','F','OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-alanine = L-alanine + peptide. The release of a C-terminal alanine from a peptide or a variety of pteroyl or acyl groups.','2013-10-27','NSRP'),(26243,50425,'carboxypeptidase B activity','F','OBSOLETE. Catalysis of the reaction: H2O + peptidyl-L-lysine (or L-arginine) = L-lysine (or L-arginine) + peptide. Preferential release of a C-terminal lysine or arginine amino acid.','2013-10-27','NSRP'),(26244,50426,'peptidyl-glycinamidase activity','F','OBSOLETE. Catalysis of the reaction: H2O + peptidyl-glycinamide = glycinamide + peptide. Cleavage of C-terminal glycinamide from a polypeptide.','2013-10-27','NSRP'),(26245,50427,'3\'-phosphoadenosine 5\'-phosphosulfate metabolic process','P','The chemical reactions and pathways involving 3\'-phosphoadenosine 5\'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.','2013-10-27','NSRP'),(26246,50428,'3\'-phosphoadenosine 5\'-phosphosulfate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of 3\'-phosphoadenosine 5\'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.','2013-10-27','NSRP'),(26247,50429,'calcium-dependent phospholipase C activity','F','Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.','2013-10-27','NSRP'),(26248,50430,'syntaxin-6 binding','F','Interacting selectively and non-covalently with the SNAP receptor syntaxin-6.','2012-03-14','NSRP'),(26249,50431,'transforming growth factor beta binding','F','Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.','2013-10-27','NSRP'),(26250,50432,'catecholamine secretion','P','The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.','2013-10-27','NSRP'),(26251,50433,'regulation of catecholamine secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.','2013-10-27','NSRP'),(26252,50434,'positive regulation of viral transcription','P','Any process that activates or increases the frequency, rate or extent of viral transcription.','2013-10-27','NSRP'),(26253,50435,'beta-amyloid metabolic process','P','The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer\'s disease, and its precursor, amyloid precursor protein (APP).','2013-10-27','NSRP'),(26254,50436,'microfibril binding','F','Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material.','2013-10-27','NSRP'),(26255,50437,'(-)-endo-fenchol synthase activity','F','Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate.','2013-10-27','NSRP'),(26256,50438,'2-ethylmalate synthase activity','F','Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+).','2013-10-27','NSRP'),(26257,50439,'2-hydroxy-3-oxoadipate synthase activity','F','Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2).','2013-10-27','NSRP'),(26258,50440,'2-methylcitrate synthase activity','F','Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).','2013-10-27','NSRP'),(26259,50441,'3-ethylmalate synthase activity','F','Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+).','2013-10-27','NSRP'),(26260,50442,'3-propylmalate synthase activity','F','Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+).','2013-10-27','NSRP'),(26261,50444,'aquacobalamin reductase (NADPH) activity','F','Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.','2013-10-27','NSRP'),(26262,50445,'asparagusate reductase activity','F','Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH.','2013-10-27','NSRP'),(26263,50446,'azobenzene reductase activity','F','Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.','2013-10-27','NSRP'),(26264,50447,'zeatin 9-aminocarboxyethyltransferase activity','F','Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+).','2013-10-27','NSRP'),(26265,50448,'beta-cyclopiazonate dehydrogenase activity','F','Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).','2013-10-27','NSRP'),(26266,50449,'casbene synthase activity','F','Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.','2013-10-27','NSRP'),(26267,50450,'citrate (Re)-synthase activity','F','Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.','2013-10-27','NSRP'),(26268,50451,'CoA-disulfide reductase activity','F','Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+.','2013-10-27','NSRP'),(26269,50452,'CoA-glutathione reductase activity','F','Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.','2013-10-27','NSRP'),(26270,50453,'cob(II)alamin reductase activity','F','Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH.','2013-10-27','NSRP'),(26271,50454,'coenzyme F420 hydrogenase activity','F','Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420.','2013-10-27','NSRP'),(26272,50455,'columbamine oxidase activity','F','Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O.','2013-10-27','NSRP'),(26273,50456,'cystine reductase activity','F','Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH.','2013-10-27','NSRP'),(26274,50457,'decylcitrate synthase activity','F','Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+).','2013-10-27','NSRP'),(26275,50458,'decylhomocitrate synthase activity','F','Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+).','2013-10-27','NSRP'),(26276,50459,'ethanolamine-phosphate phospho-lyase activity','F','Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate.','2013-10-27','NSRP'),(26277,50460,'hydroxylamine reductase (NADH) activity','F','Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.','2013-10-27','NSRP'),(26278,50461,'L-mimosine synthase activity','F','Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.','2013-10-27','NSRP'),(26279,50462,'N-acetylneuraminate synthase activity','F','Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.','2013-10-27','NSRP'),(26280,50463,'nitrate reductase [NAD(P)H] activity','F','Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.','2013-10-27','NSRP'),(26281,50464,'nitrate reductase (NADPH) activity','F','Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.','2013-10-27','NSRP'),(26282,50465,'nitroquinoline-N-oxide reductase activity','F','Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.','2013-10-27','NSRP'),(26283,50466,'oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is not disulfide or oxygen.','2013-10-27','NSRP'),(26284,50467,'pentalenene synthase activity','F','Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.','2013-10-27','NSRP'),(26285,50468,'reticuline oxidase activity','F','Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+).','2013-10-27','NSRP'),(26286,50469,'sabinene-hydrate synthase activity','F','Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate.','2013-10-27','NSRP'),(26287,50470,'trimethylamine dehydrogenase activity','F','Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.','2013-10-27','NSRP'),(26288,50471,'uracilylalanine synthase activity','F','Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.','2013-10-27','NSRP'),(26289,50472,'zeatin reductase activity','F','Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin.','2013-10-27','NSRP'),(26290,50473,'arachidonate 15-lipoxygenase activity','F','Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.','2013-10-27','NSRP'),(26291,50474,'(S)-norcoclaurine synthase activity','F','Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.','2013-10-27','NSRP'),(26292,50476,'acetylenedicarboxylate decarboxylase activity','F','Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.','2013-10-27','NSRP'),(26293,50477,'acyl-lysine deacylase activity','F','Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.','2013-10-27','NSRP'),(26294,50478,'anthranilate 3-monooxygenase activity','F','Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O.','2013-10-27','NSRP'),(26295,50479,'glyceryl-ether monooxygenase activity','F','Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).','2013-10-27','NSRP'),(26296,50480,'imidazolonepropionase activity','F','Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+).','2013-10-27','NSRP'),(26297,50481,'mandelate 4-monooxygenase activity','F','Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.','2013-10-27','NSRP'),(26298,50482,'arachidonic acid secretion','P','The controlled release of arachidonic acid from a cell or a tissue.','2013-10-27','NSRP'),(26299,50483,'IMP 5\'-nucleotidase activity','F','Catalysis of the reaction: 5\'-IMP + H2O = inosine + phosphate.','2013-10-27','NSRP'),(26300,50484,'GMP 5\'-nucleotidase activity','F','Catalysis of the reaction: 5\'-GMP + H2O = guanosine + phosphate.','2013-10-27','NSRP'),(26301,50485,'oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.','2013-10-27','NSRP'),(26302,50486,'intramolecular transferase activity, transferring hydroxy groups','F','Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.','2013-10-27','NSRP'),(26303,50487,'sulfoacetaldehyde acetyltransferase activity','F','Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.','2013-10-27','NSRP'),(26304,50488,'ecdysteroid UDP-glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.','2013-10-27','NSRP'),(26305,50490,'1,4-lactonase activity','F','Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.','2013-10-27','NSRP'),(26306,50491,'sulcatone reductase activity','F','Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone.','2013-10-27','NSRP'),(26307,50492,'glycerol-1-phosphate dehydrogenase [NAD(P)+] activity','F','Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.','2013-10-27','NSRP'),(26308,50493,'GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(26309,50494,'GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(26310,50495,'peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine.','2013-10-27','NSRP'),(26311,50496,'peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine','P','The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.','2013-10-27','NSRP'),(26312,50497,'transferase activity, transferring alkylthio groups','F','Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(26313,50498,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.','2013-10-27','NSRP'),(26314,50499,'oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.','2013-10-27','NSRP'),(26315,50500,'1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity','F','Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.','2013-10-27','NSRP'),(26316,50501,'hyaluronan synthase activity','F','Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.','2013-10-27','NSRP'),(26317,50502,'cis-zeatin O-beta-D-glucosyltransferase activity','F','Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP.','2013-10-27','NSRP'),(26318,50503,'trehalose 6-phosphate phosphorylase activity','F','Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.','2013-10-27','NSRP'),(26319,50504,'mannosyl-3-phosphoglycerate synthase activity','F','Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+).','2013-10-27','NSRP'),(26320,50505,'hydroquinone glucosyltransferase activity','F','Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP.','2013-10-27','NSRP'),(26321,50506,'vomilenine glucosyltransferase activity','F','Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP.','2013-10-27','NSRP'),(26322,50507,'indoxyl-UDPG glucosyltransferase activity','F','Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP.','2013-10-27','NSRP'),(26323,50508,'glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity','F','Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.','2013-10-27','NSRP'),(26324,50509,'N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity','F','Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.','2013-10-27','NSRP'),(26325,50510,'N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity','F','Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.','2013-10-27','NSRP'),(26326,50511,'undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity','F','Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.','2013-10-27','NSRP'),(26327,50512,'lactosylceramide 4-alpha-galactosyltransferase activity','F','Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.','2013-10-27','NSRP'),(26328,50513,'glycoprotein 2-beta-D-xylosyltransferase activity','F','Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP.','2013-10-27','NSRP'),(26329,50514,'homospermidine synthase (spermidine-specific) activity','F','Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.','2013-10-27','NSRP'),(26330,50515,'4-(cytidine 5\'-diphospho)-2-C-methyl-D-erythritol kinase activity','F','Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(26331,50516,'inositol polyphosphate multikinase activity','F','OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol 1,4,5-trisphosphate = ADP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate, and ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.','2013-10-27','NSRP'),(26332,50517,'inositol hexakisphosphate kinase activity','F','OBSOLETE. Catalysis of the reactions: ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate, and ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).','2013-10-27','NSRP'),(26333,50518,'2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity','F','Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.','2013-10-27','NSRP'),(26334,50519,'holo-citrate lyase synthase activity','F','Catalysis of the reaction: apo-citrate lyase + 2\'-(5\'\'-triphosphoribosyl)-3\'-dephospho-CoA = diphosphate + holo-citrate lyase.','2013-10-27','NSRP'),(26335,50520,'phosphatidylcholine synthase activity','F','Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+).','2013-10-27','NSRP'),(26336,50521,'alpha-glucan, water dikinase activity','F','Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate.','2013-10-27','NSRP'),(26337,50522,'oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors','F','Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP.','2013-10-27','NSRP'),(26338,50523,'oxidoreductase activity, acting on phosphorus or arsenic in donors, with other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD or NADP.','2013-10-27','NSRP'),(26339,50524,'coenzyme-B sulfoethylthiotransferase activity','F','Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.','2013-10-27','NSRP'),(26340,50525,'cutinase activity','F','Catalysis of the reaction: cutin + H2O = cutin monomers.','2013-10-27','NSRP'),(26341,50526,'poly(3-hydroxybutyrate) depolymerase activity','F','Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.','2013-10-27','NSRP'),(26342,50527,'poly(3-hydroxyoctanoate) depolymerase activity','F','Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.','2013-10-27','NSRP'),(26343,50528,'acyloxyacyl hydrolase activity','F','Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.','2013-10-27','NSRP'),(26344,50529,'polyneuridine-aldehyde esterase activity','F','Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol.','2013-10-27','NSRP'),(26345,50530,'glucosylglycerol 3-phosphatase activity','F','Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.','2013-10-27','NSRP'),(26346,50531,'mannosyl-3-phosphoglycerate phosphatase activity','F','Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.','2013-10-27','NSRP'),(26347,50532,'2-phosphosulfolactate phosphatase activity','F','Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate.','2013-10-27','NSRP'),(26348,50533,'5-phytase activity','F','Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.','2013-10-27','NSRP'),(26349,50534,'3-deoxyoctulosonase activity','F','Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.','2013-10-27','NSRP'),(26350,50535,'beta-primeverosidase activity','F','Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.','2013-10-27','NSRP'),(26351,50536,'(S)-N-acetyl-1-phenylethylamine hydrolase activity','F','Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine.','2013-10-27','NSRP'),(26352,50537,'mandelamide amidase activity','F','Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+).','2013-10-27','NSRP'),(26353,50538,'N-carbamoyl-L-amino-acid hydrolase activity','F','Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.','2013-10-27','NSRP'),(26354,50539,'maleimide hydrolase activity','F','Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate.','2013-10-27','NSRP'),(26355,50540,'2-aminomuconate deaminase activity','F','Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+).','2013-10-27','NSRP'),(26356,50541,'beta,beta-carotene-9\',10\'-dioxygenase activity','F','Catalysis of the reaction: beta-carotene + O2 = beta-apo-10\'-carotenal + beta-ionone.','2013-10-27','NSRP'),(26357,50542,'icosanoid binding','F','Interacting selectively and non-covalently with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.','2013-10-27','NSRP'),(26358,50543,'icosatetraenoic acid binding','F','Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.','2013-10-27','NSRP'),(26359,50544,'arachidonic acid binding','F','Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.','2013-10-27','NSRP'),(26360,50545,'sulfopyruvate decarboxylase activity','F','Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde.','2013-10-27','NSRP'),(26361,50546,'4-hydroxyphenylpyruvate decarboxylase activity','F','Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2).','2013-10-27','NSRP'),(26362,50547,'vanillin synthase activity','F','Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.','2013-10-27','NSRP'),(26363,50548,'trans-feruloyl-CoA hydratase activity','F','Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA.','2013-10-27','NSRP'),(26364,50549,'cyclohexyl-isocyanide hydratase activity','F','Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O.','2013-10-27','NSRP'),(26365,50550,'pinene synthase activity','F','Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate.','2013-10-27','NSRP'),(26366,50551,'myrcene synthase activity','F','Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.','2013-10-27','NSRP'),(26367,50552,'(4S)-limonene synthase activity','F','Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.','2013-10-27','NSRP'),(26368,50553,'taxadiene synthase activity','F','Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.','2013-10-27','NSRP'),(26369,50554,'abietadiene synthase activity','F','Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.','2013-10-27','NSRP'),(26370,50555,'2-hydroxypropyl-CoM lyase activity','F','Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.','2013-10-27','NSRP'),(26371,50556,'deacetylisoipecoside synthase activity','F','Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin.','2013-10-27','NSRP'),(26372,50557,'deacetylipecoside synthase activity','F','Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin.','2013-10-27','NSRP'),(26373,50558,'maltose epimerase activity','F','Catalysis of the reaction: alpha-maltose = beta-maltose.','2013-10-27','NSRP'),(26374,50559,'copalyl diphosphate synthase activity','F','Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.','2013-10-27','NSRP'),(26375,50560,'aspartate-tRNA(Asn) ligase activity','F','Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.','2013-10-27','NSRP'),(26376,50561,'glutamate-tRNA(Gln) ligase activity','F','Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.','2013-10-27','NSRP'),(26377,50562,'lysine-tRNA(Pyl) ligase activity','F','Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.','2013-10-27','NSRP'),(26378,50563,'trans-feruloyl-CoA synthase activity','F','Catalysis of the reaction: ferulic acid + CoASH + ATP = trans-feruloyl-CoA + products of ATP breakdown.','2013-10-27','NSRP'),(26379,50564,'N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity','F','Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+).','2013-10-27','NSRP'),(26380,50565,'aerobactin synthase activity','F','Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate.','2013-10-27','NSRP'),(26381,50566,'asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity','F','Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.','2013-10-27','NSRP'),(26382,50567,'glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity','F','Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.','2013-10-27','NSRP'),(26383,50568,'protein-glutamine glutaminase activity','F','Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.','2013-10-27','NSRP'),(26384,50569,'glycolaldehyde dehydrogenase activity','F','Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH.','2013-10-27','NSRP'),(26385,50570,'4-hydroxythreonine-4-phosphate dehydrogenase activity','F','Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.','2013-10-27','NSRP'),(26386,50571,'1,5-anhydro-D-fructose reductase activity','F','Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.','2013-10-27','NSRP'),(26387,50572,'L-idonate 5-dehydrogenase activity','F','Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.','2013-10-27','NSRP'),(26388,50573,'dTDP-4-dehydro-6-deoxyglucose reductase activity','F','Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH.','2013-10-27','NSRP'),(26389,50574,'2-(R)-hydroxypropyl-CoM dehydrogenase activity','F','Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.','2013-10-27','NSRP'),(26390,50575,'2-(S)-hydroxypropyl-CoM dehydrogenase activity','F','Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.','2013-10-27','NSRP'),(26391,50577,'GDP-L-fucose synthase activity','F','Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.','2013-10-27','NSRP'),(26392,50578,'(R)-2-hydroxyacid dehydrogenase activity','F','Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+.','2013-10-27','NSRP'),(26393,50579,'vellosimine dehydrogenase activity','F','Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine.','2013-10-27','NSRP'),(26394,50580,'2,5-didehydrogluconate reductase activity','F','Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.','2013-10-27','NSRP'),(26395,50581,'D-mannitol oxidase activity','F','Catalysis of the reaction: mannitol + O2 = mannose + H2O2.','2013-10-27','NSRP'),(26396,50582,'xylitol oxidase activity','F','Catalysis of the reaction: xylitol + O2 = xylose + H2O2.','2013-10-27','NSRP'),(26397,50583,'hydrogen dehydrogenase (NADP+) activity','F','Catalysis of the reaction: NADP+ + H2 = NADPH + H+.','2013-10-27','NSRP'),(26398,50584,'linoleate 11-lipoxygenase activity','F','Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.','2013-10-27','NSRP'),(26399,50585,'4-hydroxymandelate synthase activity','F','Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.','2013-10-27','NSRP'),(26400,50586,'3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity','F','Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO.','2013-10-27','NSRP'),(26401,50587,'chlorite O2-lyase activity','F','Catalysis of the reaction: chloride + O(2) = chlorite.','2013-10-27','NSRP'),(26402,50588,'apo-beta-carotenoid-14\',13\'-dioxygenase activity','F','Catalysis of the reaction: 8\'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14\'-apo-beta-carotenal.','2013-10-27','NSRP'),(26403,50589,'leucocyanidin oxygenase activity','F','Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.','2013-10-27','NSRP'),(26404,50590,'desacetoxyvindoline 4-hydroxylase activity','F','Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.','2013-10-27','NSRP'),(26405,50591,'quinine 3-monooxygenase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+).','2013-10-27','NSRP'),(26406,50592,'4-hydroxyphenylacetaldehyde oxime monooxygenase activity','F','Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+).','2013-10-27','NSRP'),(26407,50593,'N-methylcoclaurine 3\'-monooxygenase activity','F','Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3\'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+).','2013-10-27','NSRP'),(26408,50594,'tabersonine 16-hydroxylase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+).','2013-10-27','NSRP'),(26409,50595,'7-deoxyloganin 7-hydroxylase activity','F','Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O.','2013-10-27','NSRP'),(26410,50596,'vinorine hydroxylase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine.','2013-10-27','NSRP'),(26411,50597,'taxane 10-beta-hydroxylase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+).','2013-10-27','NSRP'),(26412,50598,'taxane 13-alpha-hydroxylase activity','F','Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol.','2013-10-27','NSRP'),(26413,50599,'deacetoxycephalosporin-C synthase activity','F','Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate.','2013-10-27','NSRP'),(26414,50600,'myristoyl-CoA 11-(E) desaturase activity','F','Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.','2013-10-27','NSRP'),(26415,50601,'myristoyl-CoA 11-(Z) desaturase activity','F','Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.','2013-10-27','NSRP'),(26416,50602,'monoprenyl isoflavone epoxidase activity','F','Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives.','2013-10-27','NSRP'),(26417,50603,'thiophene-2-carbonyl-CoA monooxygenase activity','F','Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+).','2013-10-27','NSRP'),(26418,50604,'taxadiene 5-alpha-hydroxylase activity','F','Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol.','2013-10-27','NSRP'),(26419,50605,'superoxide reductase activity','F','Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.','2013-10-27','NSRP'),(26420,50606,'4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity','F','Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH.','2013-10-27','NSRP'),(26421,50607,'mycothiol-dependent formaldehyde dehydrogenase activity','F','Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.','2013-10-27','NSRP'),(26422,50608,'vanillin dehydrogenase activity','F','Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.','2013-10-27','NSRP'),(26423,50609,'phosphonate dehydrogenase activity','F','Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate.','2013-10-27','NSRP'),(26424,50610,'methylarsonate reductase activity','F','Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid.','2013-10-27','NSRP'),(26425,50611,'arsenate reductase (azurin) activity','F','Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate.','2013-10-27','NSRP'),(26426,50612,'arsenate reductase (donor) activity','F','Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+).','2013-10-27','NSRP'),(26427,50613,'delta14-sterol reductase activity','F','Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.','2013-10-27','NSRP'),(26428,50614,'delta24-sterol reductase activity','F','Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.','2013-10-27','NSRP'),(26429,50615,'1,2-dihydrovomilenine reductase activity','F','Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH.','2013-10-27','NSRP'),(26430,50616,'secologanin synthase activity','F','Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.','2013-10-27','NSRP'),(26431,50617,'15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity','F','Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.','2013-10-27','NSRP'),(26432,50618,'phycoerythrobilin:ferredoxin oxidoreductase activity','F','Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.','2013-10-27','NSRP'),(26433,50619,'phytochromobilin:ferredoxin oxidoreductase activity','F','Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.','2013-10-27','NSRP'),(26434,50620,'phycocyanobilin:ferredoxin oxidoreductase activity','F','Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.','2013-10-27','NSRP'),(26435,50621,'tryptophan alpha,beta-oxidase activity','F','Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+).','2013-10-27','NSRP'),(26436,50622,'glycine dehydrogenase (cyanide-forming) activity','F','Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.','2013-10-27','NSRP'),(26437,50623,'berberine reductase activity','F','Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH.','2013-10-27','NSRP'),(26438,50624,'vomilenine reductase activity','F','Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine.','2013-10-27','NSRP'),(26439,50625,'2-hydroxy-1,4-benzoquinone reductase activity','F','Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).','2013-10-27','NSRP'),(26440,50626,'trimethylamine-N-oxide reductase (cytochrome c) activity','F','Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.','2013-10-27','NSRP'),(26441,50627,'mycothione reductase activity','F','Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.','2013-10-27','NSRP'),(26442,50628,'2-oxopropyl-CoM reductase (carboxylating) activity','F','Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH.','2013-10-27','NSRP'),(26443,50629,'tetrachloroethene reductive dehalogenase activity','F','Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor.','2013-10-27','NSRP'),(26444,50630,'(iso)eugenol O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.','2013-10-27','NSRP'),(26445,50631,'corydaline synthase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+).','2013-10-27','NSRP'),(26446,50632,'propionyl-CoA C2-trimethyltridecanoyltransferase activity','F','Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.','2013-10-27','NSRP'),(26447,50633,'acetyl-CoA C-myristoyltransferase activity','F','Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.','2013-10-27','NSRP'),(26448,50634,'phloroisovalerophenone synthase activity','F','Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.','2013-10-27','NSRP'),(26449,50635,'acridone synthase activity','F','Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O.','2013-10-27','NSRP'),(26450,50636,'vinorine synthase activity','F','Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.','2013-10-27','NSRP'),(26451,50637,'lovastatin nonaketide synthase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+).','2013-10-27','NSRP'),(26452,50638,'taxadien-5-alpha-ol O-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.','2013-10-27','NSRP'),(26453,50639,'10-hydroxytaxane O-acetyltransferase activity','F','Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.','2013-10-27','NSRP'),(26454,50640,'isopenicillin-N N-acyltransferase activity','F','Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.','2013-10-27','NSRP'),(26455,50641,'6-methylsalicylic acid synthase activity','F','Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+).','2013-10-27','NSRP'),(26456,50642,'2-alpha-hydroxytaxane 2-O-benzoyltransferase activity','F','Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.','2013-10-27','NSRP'),(26457,50643,'10-deacetylbaccatin III 10-O-acetyltransferase activity','F','Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.','2013-10-27','NSRP'),(26458,50644,'cis-p-coumarate glucosyltransferase activity','F','Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4\'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP.','2013-10-27','NSRP'),(26459,50645,'limonoid glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.','2013-10-27','NSRP'),(26460,50646,'5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding','F','Interacting selectively and non-covalently with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.','2013-10-27','NSRP'),(26461,50647,'5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding','F','Interacting selectively and non-covalently with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.','2013-10-27','NSRP'),(26462,50648,'5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding','F','Interacting selectively and non-covalently with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.','2013-10-27','NSRP'),(26463,50649,'testosterone 6-beta-hydroxylase activity','F','Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O.','2013-10-27','NSRP'),(26464,50650,'chondroitin sulfate proteoglycan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.','2013-10-27','NSRP'),(26465,50651,'dermatan sulfate proteoglycan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.','2013-10-27','NSRP'),(26466,50652,'dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process','P','The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.','2013-10-27','NSRP'),(26467,50653,'chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process','P','The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.','2013-10-27','NSRP'),(26468,50654,'chondroitin sulfate proteoglycan metabolic process','P','The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.','2013-10-27','NSRP'),(26469,50655,'dermatan sulfate proteoglycan metabolic process','P','The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.','2013-10-27','NSRP'),(26470,50656,'3\'-phosphoadenosine 5\'-phosphosulfate binding','F','Interacting selectively and non-covalently with 3\'-phosphoadenosine 5\'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.','2013-10-27','NSRP'),(26471,50657,'nucleic acid transport','P','The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26472,50658,'RNA transport','P','The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26473,50659,'N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity','F','Catalysis of the reactions: 3\'-phosphoadenylyl sulfate + dermatan = adenosine 3\',5\'-bisphosphate + dermatan 6\'-sulfate and 3\'-phosphoadenylyl sulfate + chondroitin = adenosine 3\',5\'-bisphosphate + chondroitin 6\'-sulfate.','2013-10-27','NSRP'),(26474,50660,'flavin adenine dinucleotide binding','F','Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.','2013-10-27','NSRP'),(26475,50661,'NADP binding','F','Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.','2013-10-27','NSRP'),(26476,50662,'coenzyme binding','F','Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.','2013-10-27','NSRP'),(26477,50663,'cytokine secretion','P','The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.','2013-10-27','NSRP'),(26478,50664,'oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.','2013-10-27','NSRP'),(26479,50665,'hydrogen peroxide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.','2013-10-27','NSRP'),(26480,50666,'regulation of homocysteine metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.','2013-10-27','NSRP'),(26481,50667,'homocysteine metabolic process','P','The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.','2013-10-27','NSRP'),(26482,50668,'positive regulation of homocysteine metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.','2013-10-27','NSRP'),(26483,50669,'negative regulation of homocysteine metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.','2013-10-27','NSRP'),(26484,50670,'regulation of lymphocyte proliferation','P','Any process that modulates the frequency, rate or extent of lymphocyte proliferation.','2013-10-27','NSRP'),(26485,50671,'positive regulation of lymphocyte proliferation','P','Any process that activates or increases the rate or extent of lymphocyte proliferation.','2013-10-27','NSRP'),(26486,50672,'negative regulation of lymphocyte proliferation','P','Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.','2013-10-27','NSRP'),(26487,50673,'epithelial cell proliferation','P','The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.','2013-10-27','NSRP'),(26488,50674,'urothelial cell proliferation','P','The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.','2013-10-27','NSRP'),(26489,50675,'regulation of urothelial cell proliferation','P','Any process that modulates the frequency, rate or extent of urothelial cell proliferation.','2013-10-27','NSRP'),(26490,50676,'negative regulation of urothelial cell proliferation','P','Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.','2013-10-27','NSRP'),(26491,50677,'positive regulation of urothelial cell proliferation','P','Any process that activates or increases the rate or extent of urothelial cell proliferation.','2013-10-27','NSRP'),(26492,50678,'regulation of epithelial cell proliferation','P','Any process that modulates the frequency, rate or extent of epithelial cell proliferation.','2013-10-27','NSRP'),(26493,50679,'positive regulation of epithelial cell proliferation','P','Any process that activates or increases the rate or extent of epithelial cell proliferation.','2013-10-27','NSRP'),(26494,50680,'negative regulation of epithelial cell proliferation','P','Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.','2013-10-27','NSRP'),(26495,50681,'androgen receptor binding','F','Interacting selectively and non-covalently with an androgen receptor.','2013-10-27','NSRP'),(26496,50682,'AF-2 domain binding','F','Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.','2013-10-27','NSRP'),(26497,50683,'AF-1 domain binding','F','Interacting selectively and non-covalently with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.','2013-10-27','NSRP'),(26498,50684,'regulation of mRNA processing','P','Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.','2013-10-27','NSRP'),(26499,50685,'positive regulation of mRNA processing','P','Any process that activates or increases the frequency, rate or extent of mRNA processing.','2013-10-27','NSRP'),(26500,50686,'negative regulation of mRNA processing','P','Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.','2013-10-27','NSRP'),(26501,50687,'negative regulation of defense response to virus','P','Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.','2013-10-27','NSRP'),(26502,50688,'regulation of defense response to virus','P','Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.','2013-10-27','NSRP'),(26503,50689,'negative regulation of defense response to virus by host','P','Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.','2013-10-27','NSRP'),(26504,50690,'regulation of defense response to virus by virus','P','Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.','2013-10-27','NSRP'),(26505,50691,'regulation of defense response to virus by host','P','Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.','2013-10-27','NSRP'),(26506,50692,'DBD domain binding','F','Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.','2013-10-27','NSRP'),(26507,50693,'LBD domain binding','F','Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.','2013-10-27','NSRP'),(26508,50694,'galactose 3-O-sulfotransferase activity','F','Catalysis of the reaction: N-acetyllactosamine + 3\'-phosphoadenosine 5\'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3\',5\'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.','2013-10-27','NSRP'),(26509,50695,'benzoylformate decarboxylase activity','F','Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.','2013-10-27','NSRP'),(26510,50696,'trichloroethylene catabolic process','P','The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.','2013-10-27','NSRP'),(26511,50697,'1,1,2-trichloroethene reductive dehalogenase activity','F','Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.','2013-10-27','NSRP'),(26512,50698,'proteoglycan sulfotransferase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + proteoglycan = adenosine 3\',5\'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.','2013-10-27','NSRP'),(26513,50699,'WW domain binding','F','Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.','2013-10-27','NSRP'),(26514,50700,'CARD domain binding','F','Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.','2013-10-27','NSRP'),(26515,50701,'interleukin-1 secretion','P','The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response.','2013-10-27','NSRP'),(26516,50702,'interleukin-1 beta secretion','P','The regulated release of interleukin 1 beta from a cell.','2013-10-27','NSRP'),(26517,50703,'interleukin-1 alpha secretion','P','The regulated release of interleukin-1 alpha from a cell.','2013-10-27','NSRP'),(26518,50704,'regulation of interleukin-1 secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell.','2013-10-27','NSRP'),(26519,50705,'regulation of interleukin-1 alpha secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.','2013-10-27','NSRP'),(26520,50706,'regulation of interleukin-1 beta secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.','2013-10-27','NSRP'),(26521,50707,'regulation of cytokine secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell.','2013-10-27','NSRP'),(26522,50708,'regulation of protein secretion','P','Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.','2013-10-27','NSRP'),(26523,50709,'negative regulation of protein secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.','2013-10-27','NSRP'),(26524,50710,'negative regulation of cytokine secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell.','2013-10-27','NSRP'),(26525,50711,'negative regulation of interleukin-1 secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell.','2013-10-27','NSRP'),(26526,50712,'negative regulation of interleukin-1 alpha secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.','2013-10-27','NSRP'),(26527,50713,'negative regulation of interleukin-1 beta secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.','2013-10-27','NSRP'),(26528,50714,'positive regulation of protein secretion','P','Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.','2013-10-27','NSRP'),(26529,50715,'positive regulation of cytokine secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell.','2013-10-27','NSRP'),(26530,50716,'positive regulation of interleukin-1 secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell.','2013-10-27','NSRP'),(26531,50717,'positive regulation of interleukin-1 alpha secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.','2013-10-27','NSRP'),(26532,50718,'positive regulation of interleukin-1 beta secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.','2013-10-27','NSRP'),(26533,50719,'interleukin-1 alpha biosynthetic process','P','The chemical reactions and pathways resulting in the formation of interleukin-1 alpha.','2013-10-27','NSRP'),(26534,50720,'interleukin-1 beta biosynthetic process','P','The chemical reactions and pathways resulting in the formation of interleukin-1 beta.','2013-10-27','NSRP'),(26535,50721,'regulation of interleukin-1 alpha biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.','2013-10-27','NSRP'),(26536,50722,'regulation of interleukin-1 beta biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.','2013-10-27','NSRP'),(26537,50723,'negative regulation of interleukin-1 alpha biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.','2013-10-27','NSRP'),(26538,50724,'negative regulation of interleukin-1 beta biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.','2013-10-27','NSRP'),(26539,50725,'positive regulation of interleukin-1 beta biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.','2013-10-27','NSRP'),(26540,50726,'positive regulation of interleukin-1 alpha biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.','2013-10-27','NSRP'),(26541,50727,'regulation of inflammatory response','P','Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.','2013-10-27','NSRP'),(26542,50728,'negative regulation of inflammatory response','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.','2013-10-27','NSRP'),(26543,50729,'positive regulation of inflammatory response','P','Any process that activates or increases the frequency, rate or extent of the inflammatory response.','2013-10-27','NSRP'),(26544,50730,'regulation of peptidyl-tyrosine phosphorylation','P','Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.','2013-10-27','NSRP'),(26545,50731,'positive regulation of peptidyl-tyrosine phosphorylation','P','Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.','2013-10-27','NSRP'),(26546,50732,'negative regulation of peptidyl-tyrosine phosphorylation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.','2013-10-27','NSRP'),(26547,50733,'RS domain binding','F','Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.','2013-10-27','NSRP'),(26548,50734,'hydroxycinnamoyltransferase activity','F','Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.','2013-10-27','NSRP'),(26549,50735,'N-malonyltransferase activity','F','Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.','2013-10-27','NSRP'),(26550,50736,'O-malonyltransferase activity','F','Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(26551,50737,'O-hydroxycinnamoyltransferase activity','F','Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(26552,50738,'fructosyltransferase activity','F','Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.','2013-10-27','NSRP'),(26553,50739,'peptide cross-linking via S-[5\'-(L-tryptoph-6\'-yl)-L-tyrosin-3\'-yl]-L-methionin-S-ium','P','The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5\'-(L-tryptoph-6\'-yl)-L-tyrosin-3\'-yl]-L-methionin-S-ium.','2013-10-27','NSRP'),(26554,50740,'protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine','P','The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine.','2013-10-27','NSRP'),(26555,50741,'protein-FMN linkage via O3-riboflavin phosphoryl-L-serine','P','The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine.','2013-10-27','NSRP'),(26556,50742,'protein-FMN linkage via S-(4a-FMN)-L-cysteine','P','The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine.','2013-10-27','NSRP'),(26557,50743,'protein-FMN linkage via 1\'-(8alpha-FMN)-L-histidine','P','The formation of a protein-FMN linkage via 1\'-(8alpha-FMN)-L-histidine.','2013-10-27','NSRP'),(26558,50744,'protein-FMN linkage via 3\'-(8alpha-FMN)-L-histidine','P','The formation of a protein-FMN linkage via 3\'-(8alpha-FMN)-L-histidine.','2013-10-27','NSRP'),(26559,50745,'peptide cross-linking via L-cysteinyl-5-imidazolinone glycine','P','The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.','2013-10-27','NSRP'),(26560,50746,'regulation of lipoprotein metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.','2013-10-27','NSRP'),(26561,50747,'positive regulation of lipoprotein metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.','2013-10-27','NSRP'),(26562,50748,'negative regulation of lipoprotein metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.','2013-10-27','NSRP'),(26563,50749,'apolipoprotein E receptor binding','F','OBSOLETE. Interacting selectively with an apolipoprotein E receptor.','2013-10-27','NSRP'),(26564,50750,'low-density lipoprotein particle receptor binding','F','Interacting selectively and non-covalently with a low-density lipoprotein receptor.','2013-10-27','NSRP'),(26565,50751,'fractalkine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.','2013-10-27','NSRP'),(26566,50752,'regulation of fractalkine biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.','2013-10-27','NSRP'),(26567,50753,'negative regulation of fractalkine biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.','2013-10-27','NSRP'),(26568,50754,'positive regulation of fractalkine biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.','2013-10-27','NSRP'),(26569,50755,'chemokine metabolic process','P','The chemical reactions and pathways involving chemokines, any of a subgroup of cytokines which act primarily on hemopoietic cells in acute and inflammatory processes and other immunoregulatory functions.','2013-10-27','NSRP'),(26570,50756,'fractalkine metabolic process','P','The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.','2013-10-27','NSRP'),(26571,50757,'thymidylate synthase biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.','2013-10-27','NSRP'),(26572,50758,'regulation of thymidylate synthase biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.','2013-10-27','NSRP'),(26573,50759,'positive regulation of thymidylate synthase biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.','2013-10-27','NSRP'),(26574,50760,'negative regulation of thymidylate synthase biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.','2013-10-27','NSRP'),(26575,50761,'depsipeptide metabolic process','P','The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.','2013-10-27','NSRP'),(26576,50762,'depsipeptide catabolic process','P','The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.','2013-10-27','NSRP'),(26577,50763,'depsipeptide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.','2013-10-27','NSRP'),(26578,50764,'regulation of phagocytosis','P','Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.','2013-10-27','NSRP'),(26579,50765,'negative regulation of phagocytosis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.','2013-10-27','NSRP'),(26580,50766,'positive regulation of phagocytosis','P','Any process that activates or increases the frequency, rate or extent of phagocytosis.','2013-10-27','NSRP'),(26581,50767,'regulation of neurogenesis','P','Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.','2013-10-27','NSRP'),(26582,50768,'negative regulation of neurogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons.','2013-10-27','NSRP'),(26583,50769,'positive regulation of neurogenesis','P','Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.','2013-10-27','NSRP'),(26584,50770,'regulation of axonogenesis','P','Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.','2013-10-27','NSRP'),(26585,50771,'negative regulation of axonogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.','2013-10-27','NSRP'),(26586,50772,'positive regulation of axonogenesis','P','Any process that activates or increases the frequency, rate or extent of axonogenesis.','2013-10-27','NSRP'),(26587,50773,'regulation of dendrite development','P','Any process that modulates the frequency, rate or extent of dendrite development.','2013-10-27','NSRP'),(26588,50774,'negative regulation of dendrite morphogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.','2013-10-27','NSRP'),(26589,50775,'positive regulation of dendrite morphogenesis','P','Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.','2013-10-27','NSRP'),(26590,50776,'regulation of immune response','P','Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.','2013-10-27','NSRP'),(26591,50777,'negative regulation of immune response','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.','2013-10-27','NSRP'),(26592,50778,'positive regulation of immune response','P','Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.','2013-10-27','NSRP'),(26593,50779,'RNA destabilization','P','Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.','2013-10-27','NSRP'),(26594,50780,'dopamine receptor binding','F','Interacting selectively and non-covalently with a dopamine receptor.','2013-10-27','NSRP'),(26595,50781,'ortho-trichlorophenol reductive dehalogenase activity','F','Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.','2013-10-27','NSRP'),(26596,50782,'galactose uniporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).','2013-10-27','NSRP'),(26597,50783,'cocaine metabolic process','P','The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.','2013-10-27','NSRP'),(26598,50784,'cocaine catabolic process','P','The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.','2013-10-27','NSRP'),(26599,50785,'advanced glycation end-product receptor activity','F','Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).','2013-10-27','NSRP'),(26600,50786,'RAGE receptor binding','F','Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products.','2013-10-27','NSRP'),(26601,50787,'detoxification of mercury ion','P','Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).','2013-10-27','NSRP'),(26602,50788,'sequestering of mercury','P','The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.','2013-10-27','NSRP'),(26603,50789,'regulation of biological process','P','Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.','2013-10-27','NSRP'),(26604,50790,'regulation of catalytic activity','P','Any process that modulates the activity of an enzyme.','2013-10-27','NSRP'),(26605,50792,'regulation of viral process','P','Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.','2013-10-27','NSRP'),(26606,50793,'regulation of developmental process','P','Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).','2013-10-27','NSRP'),(26607,50794,'regulation of cellular process','P','Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.','2013-10-27','NSRP'),(26608,50795,'regulation of behavior','P','Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.','2013-10-27','NSRP'),(26609,50796,'regulation of insulin secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of insulin.','2013-10-27','NSRP'),(26610,50797,'thymidylate synthase (FAD) activity','F','Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.','2013-10-27','NSRP'),(26611,50798,'activated T cell proliferation','P','The expansion of a T cell population following activation by an antigenic stimulus.','2013-10-27','NSRP'),(26612,50799,'cocaine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.','2013-10-27','NSRP'),(26613,50800,'hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement','F','OBSOLETE. Catalysis of the hydrolysis of GTP to directly drive the cellular or subcellular transport of a substance.','2013-10-27','NSRP'),(26614,50801,'ion homeostasis','P','Any process involved in the maintenance of an internal steady state of ions within an organism or cell.','2013-10-27','NSRP'),(26615,50802,'circadian sleep/wake cycle, sleep','P','The part of the circadian sleep/wake cycle where the organism is asleep.','2013-10-27','NSRP'),(26616,50803,'regulation of synapse structure and activity','P','Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).','2013-10-27','NSRP'),(26617,50804,'regulation of synaptic transmission','P','Any process that modulates the frequency or rate of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.','2013-10-27','NSRP'),(26618,50805,'negative regulation of synaptic transmission','P','Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.','2013-10-27','NSRP'),(26619,50806,'positive regulation of synaptic transmission','P','Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.','2013-10-27','NSRP'),(26620,50807,'regulation of synapse organization','P','Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).','2013-10-27','NSRP'),(26621,50808,'synapse organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).','2013-10-27','NSRP'),(26622,50809,'diazepam binding','F','Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.','2013-10-27','NSRP'),(26623,50810,'regulation of steroid biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.','2013-10-27','NSRP'),(26624,50811,'GABA receptor binding','F','Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.','2013-10-27','NSRP'),(26625,50812,'regulation of acyl-CoA biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.','2013-10-27','NSRP'),(26626,50813,'epothilone metabolic process','P','The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.','2013-10-27','NSRP'),(26627,50814,'epothilone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.','2013-10-27','NSRP'),(26628,50815,'phosphoserine binding','F','Interacting selectively and non-covalently with a phosphorylated serine residue within a protein.','2013-10-27','NSRP'),(26629,50816,'phosphothreonine binding','F','Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein.','2013-10-27','NSRP'),(26630,50817,'coagulation','P','The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.','2013-10-27','NSRP'),(26631,50818,'regulation of coagulation','P','Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.','2013-10-27','NSRP'),(26632,50819,'negative regulation of coagulation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.','2013-10-27','NSRP'),(26633,50820,'positive regulation of coagulation','P','Any process that activates or increases the frequency, rate or extent of coagulation.','2013-10-27','NSRP'),(26634,50821,'protein stabilization','P','Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.','2013-10-27','NSRP'),(26635,50822,'peptide stabilization','P','Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.','2013-10-27','NSRP'),(26636,50823,'peptide antigen stabilization','P','Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.','2013-10-27','NSRP'),(26637,50824,'water binding','F','Interacting selectively and non-covalently with water (H2O).','2013-10-27','NSRP'),(26638,50825,'ice binding','F','Interacting selectively and non-covalently with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.','2013-10-27','NSRP'),(26639,50826,'response to freezing','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.','2013-10-27','NSRP'),(26640,50827,'toxin receptor binding','F','Interacting selectively and non-covalently with a toxin receptor, a receptor for substances that cause injury to living organisms.','2013-10-27','NSRP'),(26641,50828,'regulation of liquid surface tension','P','Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.','2013-10-27','NSRP'),(26642,50829,'defense response to Gram-negative bacterium','P','Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.','2013-10-27','NSRP'),(26643,50830,'defense response to Gram-positive bacterium','P','Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.','2013-10-27','NSRP'),(26644,50831,'male-specific defense response to bacterium','P','A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.','2013-10-27','NSRP'),(26645,50832,'defense response to fungus','P','Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.','2013-10-27','NSRP'),(26646,50833,'pyruvate transmembrane transporter activity','F','Catalysis of the transfer of pyruvate, 2-oxopropanoate, from one side of the membrane to the other.','2013-10-27','NSRP'),(26647,50834,'molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide','P','The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.','2013-10-27','NSRP'),(26648,50835,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.','2013-10-27','NSRP'),(26649,50836,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.','2013-10-27','NSRP'),(26650,50837,'peptide cross-linking via L-cysteinyl-L-selenocysteine','P','The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P.','2013-10-27','NSRP'),(26651,50838,'peptidyl-5-hydroxy-L-lysine trimethylation','P','The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.','2013-10-27','NSRP'),(26652,50839,'cell adhesion molecule binding','F','Interacting selectively and non-covalently with a cell adhesion molecule.','2013-10-27','NSRP'),(26653,50840,'extracellular matrix binding','F','Interacting selectively and non-covalently with a component of the extracellular matrix.','2013-10-27','NSRP'),(26654,50841,'peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine','P','The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.','2013-10-27','NSRP'),(26655,50842,'copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide','P','The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.','2013-10-27','NSRP'),(26656,50843,'S-adenosylmethionine catabolic process','P','The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5\'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.','2013-10-27','NSRP'),(26657,50844,'peptidyl-selenocysteine modification','P','The modification of peptidyl-selenocysteine.','2013-10-27','NSRP'),(26658,50845,'teichuronic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.','2013-10-27','NSRP'),(26659,50846,'teichuronic acid metabolic process','P','The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.','2013-10-27','NSRP'),(26660,50847,'progesterone receptor signaling pathway','P','Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.','2013-10-27','NSRP'),(26661,50848,'regulation of calcium-mediated signaling','P','Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.','2013-10-27','NSRP'),(26662,50849,'negative regulation of calcium-mediated signaling','P','Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.','2013-10-27','NSRP'),(26663,50850,'positive regulation of calcium-mediated signaling','P','Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.','2013-10-27','NSRP'),(26664,50851,'antigen receptor-mediated signaling pathway','P','A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.','2013-10-27','NSRP'),(26665,50852,'T cell receptor signaling pathway','P','A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.','2013-10-27','NSRP'),(26666,50853,'B cell receptor signaling pathway','P','A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.','2013-10-27','NSRP'),(26667,50854,'regulation of antigen receptor-mediated signaling pathway','P','Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.','2013-10-27','NSRP'),(26668,50855,'regulation of B cell receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.','2013-10-27','NSRP'),(26669,50856,'regulation of T cell receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.','2013-10-27','NSRP'),(26670,50857,'positive regulation of antigen receptor-mediated signaling pathway','P','Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.','2013-10-27','NSRP'),(26671,50858,'negative regulation of antigen receptor-mediated signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.','2013-10-27','NSRP'),(26672,50859,'negative regulation of B cell receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.','2013-10-27','NSRP'),(26673,50860,'negative regulation of T cell receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.','2013-10-27','NSRP'),(26674,50861,'positive regulation of B cell receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.','2013-10-27','NSRP'),(26675,50862,'positive regulation of T cell receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.','2013-10-27','NSRP'),(26676,50863,'regulation of T cell activation','P','Any process that modulates the frequency, rate or extent of T cell activation.','2013-10-27','NSRP'),(26677,50864,'regulation of B cell activation','P','Any process that modulates the frequency, rate or extent of B cell activation.','2013-10-27','NSRP'),(26678,50865,'regulation of cell activation','P','Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.','2013-10-27','NSRP'),(26679,50866,'negative regulation of cell activation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.','2013-10-27','NSRP'),(26680,50867,'positive regulation of cell activation','P','Any process that activates or increases the frequency, rate or extent of activation.','2013-10-27','NSRP'),(26681,50868,'negative regulation of T cell activation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.','2013-10-27','NSRP'),(26682,50869,'negative regulation of B cell activation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.','2013-10-27','NSRP'),(26683,50870,'positive regulation of T cell activation','P','Any process that activates or increases the frequency, rate or extent of T cell activation.','2013-10-27','NSRP'),(26684,50871,'positive regulation of B cell activation','P','Any process that activates or increases the frequency, rate or extent of B cell activation.','2013-10-27','NSRP'),(26685,50872,'white fat cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.','2013-10-27','NSRP'),(26686,50873,'brown fat cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.','2013-10-27','NSRP'),(26687,50877,'neurological system process','P','A organ system process carried out by any of the organs or tissues of neurological system.','2013-10-27','NSRP'),(26688,50878,'regulation of body fluid levels','P','Any process that modulates the levels of body fluids.','2013-10-27','NSRP'),(26689,50879,'multicellular organismal movement','P','Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.','2013-10-27','NSRP'),(26690,50880,'regulation of blood vessel size','P','Any process that modulates the size of blood vessels.','2013-10-27','NSRP'),(26691,50881,'musculoskeletal movement','P','The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.','2013-10-27','NSRP'),(26692,50882,'voluntary musculoskeletal movement','P','The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.','2013-10-27','NSRP'),(26693,50883,'musculoskeletal movement, spinal reflex action','P','Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.','2013-10-27','NSRP'),(26694,50884,'neuromuscular process controlling posture','P','Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.','2013-10-27','NSRP'),(26695,50885,'neuromuscular process controlling balance','P','Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.','2013-10-27','NSRP'),(26696,50886,'endocrine process','P','The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.','2013-10-27','NSRP'),(26697,50887,'determination of sensory modality','P','The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.','2013-10-27','NSRP'),(26698,50888,'determination of stimulus location','P','The determination of where on the body surface, within the body or in the environment a stimulus originates.','2013-10-27','NSRP'),(26699,50889,'determination of stimulus intensity','P','The determination of the perceived strength of a sensory stimulus.','2013-10-27','NSRP'),(26700,50890,'cognition','P','The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.','2013-10-27','NSRP'),(26701,50891,'multicellular organismal water homeostasis','P','Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.','2013-10-27','NSRP'),(26702,50892,'intestinal absorption','P','Any process in which nutrients are taken up from the contents of the intestine.','2013-10-27','NSRP'),(26703,50893,'sensory processing','P','Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.','2013-10-27','NSRP'),(26704,50894,'determination of affect','P','Any process in which an emotional response is associated with a particular sensory stimulation.','2013-10-27','NSRP'),(26705,50896,'response to stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.','2013-10-27','NSRP'),(26706,50897,'cobalt ion binding','F','Interacting selectively and non-covalently with a cobalt (Co) ion.','2013-10-27','NSRP'),(26707,50898,'nitrile metabolic process','P','The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.','2013-10-27','NSRP'),(26708,50899,'nitrile catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.','2013-10-27','NSRP'),(26709,50900,'leukocyte migration','P','The movement of a leukocyte within or between different tissues and organs of the body.','2013-10-27','NSRP'),(26710,50901,'leukocyte tethering or rolling','P','Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).','2013-10-27','NSRP'),(26711,50902,'leukocyte adhesive activation','P','The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.','2013-10-27','NSRP'),(26712,50903,'leukocyte activation-dependent arrest','P','The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.','2013-10-27','NSRP'),(26713,50904,'diapedesis','P','The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.','2013-10-27','NSRP'),(26714,50905,'neuromuscular process','P','Any process pertaining to the functions of the nervous and muscular systems of an organism.','2013-10-27','NSRP'),(26715,50906,'detection of stimulus involved in sensory perception','P','The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26716,50907,'detection of chemical stimulus involved in sensory perception','P','The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.','2013-10-27','NSRP'),(26717,50908,'detection of light stimulus involved in visual perception','P','The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26718,50909,'sensory perception of taste','P','The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.','2013-10-27','NSRP'),(26719,50910,'detection of mechanical stimulus involved in sensory perception of sound','P','The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.','2013-10-27','NSRP'),(26720,50911,'detection of chemical stimulus involved in sensory perception of smell','P','The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26721,50912,'detection of chemical stimulus involved in sensory perception of taste','P','The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26722,50913,'sensory perception of bitter taste','P','The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26723,50914,'sensory perception of salty taste','P','The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26724,50915,'sensory perception of sour taste','P','The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26725,50916,'sensory perception of sweet taste','P','The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26726,50917,'sensory perception of umami taste','P','The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.','2013-10-27','NSRP'),(26727,50918,'positive chemotaxis','P','The directed movement of a motile cell or organism towards a higher concentration of a chemical.','2013-10-27','NSRP'),(26728,50919,'negative chemotaxis','P','The directed movement of a motile cell or organism towards a lower concentration of a chemical.','2013-10-27','NSRP'),(26729,50920,'regulation of chemotaxis','P','Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.','2013-10-27','NSRP'),(26730,50921,'positive regulation of chemotaxis','P','Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.','2013-10-27','NSRP'),(26731,50922,'negative regulation of chemotaxis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.','2013-10-27','NSRP'),(26732,50923,'regulation of negative chemotaxis','P','Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26733,50924,'positive regulation of negative chemotaxis','P','Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26734,50925,'negative regulation of negative chemotaxis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26735,50926,'regulation of positive chemotaxis','P','Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26736,50927,'positive regulation of positive chemotaxis','P','Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26737,50928,'negative regulation of positive chemotaxis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26738,50929,'induction of negative chemotaxis','P','Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26739,50930,'induction of positive chemotaxis','P','Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.','2013-10-27','NSRP'),(26740,50931,'pigment cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.','2013-10-27','NSRP'),(26741,50932,'regulation of pigment cell differentiation','P','Any process that modulates the frequency, rate or extent of pigmented cell differentiation.','2013-10-27','NSRP'),(26742,50933,'early stripe melanocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).','2013-10-27','NSRP'),(26743,50934,'late stripe melanocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).','2013-10-27','NSRP'),(26744,50935,'iridophore differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.','2013-10-27','NSRP'),(26745,50936,'xanthophore differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.','2013-10-27','NSRP'),(26746,50937,'regulation of iridophore differentiation','P','Any process that modulates the frequency, rate or extent of iridophore differentiation.','2013-10-27','NSRP'),(26747,50938,'regulation of xanthophore differentiation','P','Any process that modulates the frequency, rate or extent of xanthophore differentiation.','2013-10-27','NSRP'),(26748,50939,'regulation of early stripe melanocyte differentiation','P','Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.','2013-10-27','NSRP'),(26749,50940,'regulation of late stripe melanocyte differentiation','P','Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.','2013-10-27','NSRP'),(26750,50941,'negative regulation of pigment cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.','2013-10-27','NSRP'),(26751,50942,'positive regulation of pigment cell differentiation','P','Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.','2013-10-27','NSRP'),(26752,50943,'negative regulation of iridophore differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.','2013-10-27','NSRP'),(26753,50944,'negative regulation of xanthophore differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.','2013-10-27','NSRP'),(26754,50945,'positive regulation of iridophore differentiation','P','Any process that activates or increases the frequency, rate or extent of iridophore differentiation.','2013-10-27','NSRP'),(26755,50946,'positive regulation of xanthophore differentiation','P','Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.','2013-10-27','NSRP'),(26756,50947,'negative regulation of early stripe melanocyte differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.','2013-10-27','NSRP'),(26757,50948,'positive regulation of early stripe melanocyte differentiation','P','Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.','2013-10-27','NSRP'),(26758,50949,'negative regulation of late stripe melanocyte differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.','2013-10-27','NSRP'),(26759,50950,'positive regulation of late stripe melanocyte differentiation','P','Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.','2013-10-27','NSRP'),(26760,50951,'sensory perception of temperature stimulus','P','The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26761,50952,'sensory perception of electrical stimulus','P','The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26762,50953,'sensory perception of light stimulus','P','The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26763,50954,'sensory perception of mechanical stimulus','P','The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.','2013-10-27','NSRP'),(26764,50955,'thermoception','P','The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).','2013-10-27','NSRP'),(26765,50956,'electroception','P','The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.','2013-10-27','NSRP'),(26766,50957,'equilibrioception','P','The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.','2013-10-27','NSRP'),(26767,50958,'magnetoreception','P','The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.','2013-10-27','NSRP'),(26768,50959,'echolocation','P','Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.','2013-10-27','NSRP'),(26769,50960,'detection of temperature stimulus involved in thermoception','P','The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.','2013-10-27','NSRP'),(26770,50961,'detection of temperature stimulus involved in sensory perception','P','The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.','2013-10-27','NSRP'),(26771,50962,'detection of light stimulus involved in sensory perception','P','The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.','2013-10-27','NSRP'),(26772,50963,'detection of electrical stimulus involved in sensory perception','P','The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.','2013-10-27','NSRP'),(26773,50964,'detection of electrical stimulus involved in electroception','P','The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26774,50965,'detection of temperature stimulus involved in sensory perception of pain','P','The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26775,50966,'detection of mechanical stimulus involved in sensory perception of pain','P','The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26776,50967,'detection of electrical stimulus involved in sensory perception of pain','P','The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26777,50968,'detection of chemical stimulus involved in sensory perception of pain','P','The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26778,50969,'detection of chemical stimulus involved in magnetoreception','P','The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.','2013-10-27','NSRP'),(26779,50970,'detection of electrical stimulus involved in magnetoreception','P','The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.','2013-10-27','NSRP'),(26780,50971,'detection of mechanical stimulus involved in magnetoreception','P','The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.','2013-10-27','NSRP'),(26781,50972,'detection of mechanical stimulus involved in echolocation','P','The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.','2013-10-27','NSRP'),(26782,50973,'detection of mechanical stimulus involved in equilibrioception','P','The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.','2013-10-27','NSRP'),(26783,50974,'detection of mechanical stimulus involved in sensory perception','P','The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.','2013-10-27','NSRP'),(26784,50975,'sensory perception of touch','P','The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).','2013-10-27','NSRP'),(26785,50976,'detection of mechanical stimulus involved in sensory perception of touch','P','The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26786,50977,'magnetoreception by sensory perception of chemical stimulus','P','The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a \'chemical compass\': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.','2013-10-27','NSRP'),(26787,50978,'magnetoreception by sensory perception of electrical stimulus','P','The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.','2013-10-27','NSRP'),(26788,50979,'magnetoreception by sensory perception of mechanical stimulus','P','The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.','2013-10-27','NSRP'),(26789,50980,'detection of light stimulus involved in magnetoreception','P','The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.','2013-10-27','NSRP'),(26790,50981,'detection of electrical stimulus','P','The series of events by which an electrical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26791,50982,'detection of mechanical stimulus','P','The series of events by which a mechanical stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(26792,50983,'deoxyhypusine biosynthetic process from spermidine','P','The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.','2013-10-27','NSRP'),(26793,50984,'peptidyl-serine sulfation','P','The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.','2013-10-27','NSRP'),(26794,50985,'peptidyl-threonine sulfation','P','The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.','2013-10-27','NSRP'),(26795,50986,'isopeptide cross-linking via N-(L-isoglutamyl)-glycine','P','The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.','2013-10-27','NSRP'),(26796,50987,'enzyme active site formation via O-sulfo-L-serine','P','The transient sulfation of peptidyl-serine to form O-sulfo-L-serine.','2013-10-27','NSRP'),(26797,50988,'N-terminal peptidyl-methionine carboxylation','P','The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.','2013-10-27','NSRP'),(26798,50989,'N-terminal protein amino acid carboxylation','P','The carboxylation of the N-terminal amino acid of proteins.','2013-10-27','NSRP'),(26799,50990,'N-terminal protein amino acid carbamoylation','P','The carbamoylation of the N-terminal amino acid of proteins.','2013-10-27','NSRP'),(26800,50991,'enzyme active site formation via O-sulfo-L-threonine','P','The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine.','2013-10-27','NSRP'),(26801,50992,'dimethylallyl diphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.','2013-10-27','NSRP'),(26802,50993,'dimethylallyl diphosphate metabolic process','P','The chemical reactions and pathways involving dimethylallyl diphosphate.','2013-10-27','NSRP'),(26803,50994,'regulation of lipid catabolic process','P','Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.','2013-10-27','NSRP'),(26804,50995,'negative regulation of lipid catabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.','2013-10-27','NSRP'),(26805,50996,'positive regulation of lipid catabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.','2013-10-27','NSRP'),(26806,50997,'quaternary ammonium group binding','F','Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.','2013-10-27','NSRP'),(26807,50998,'nitric-oxide synthase binding','F','Interacting selectively and non-covalently with the enzyme nitric-oxide synthase.','2013-10-27','NSRP'),(26808,50999,'regulation of nitric-oxide synthase activity','P','Any process that modulates the activity of the enzyme nitric-oxide synthase.','2013-10-27','NSRP'),(26809,51000,'positive regulation of nitric-oxide synthase activity','P','Any process that activates or increases the activity of the enzyme nitric-oxide synthase.','2013-10-27','NSRP'),(26810,51001,'negative regulation of nitric-oxide synthase activity','P','Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.','2013-10-27','NSRP'),(26811,51002,'ligase activity, forming nitrogen-metal bonds','F','Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(26812,51003,'ligase activity, forming nitrogen-metal bonds, forming coordination complexes','F','Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.','2013-10-27','NSRP'),(26813,51004,'regulation of lipoprotein lipase activity','P','Any process that modulates the activity of the enzyme lipoprotein lipase.','2013-10-27','NSRP'),(26814,51005,'negative regulation of lipoprotein lipase activity','P','Any process that stops or reduces the activity of the enzyme lipoprotein lipase.','2013-10-27','NSRP'),(26815,51006,'positive regulation of lipoprotein lipase activity','P','Any process that activates or increases the activity of the enzyme lipoprotein lipase.','2013-10-27','NSRP'),(26816,51007,'squalene-hopene cyclase activity','F','Catalysis of the reaction: squalene = hop-22(29)-ene.','2013-10-27','NSRP'),(26817,51008,'Hsp27 protein binding','F','Interacting selectively and non-covalently with Hsp27 proteins, a lightweight heat shock protein.','2013-10-27','NSRP'),(26818,51009,'O-acetylhomoserine sulfhydrylase activity','F','Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.','2013-10-27','NSRP'),(26819,51010,'microtubule plus-end binding','F','Interacting selectively and non-covalently with the plus end of a microtubule.','2013-10-27','NSRP'),(26820,51011,'microtubule minus-end binding','F','Interacting selectively and non-covalently with the minus end of a microtubule.','2013-10-27','NSRP'),(26821,51012,'microtubule sliding','P','The movement of one microtubule along another microtubule.','2013-10-27','NSRP'),(26822,51013,'microtubule severing','P','The process in which a microtubule is broken down into smaller segments.','2013-10-27','NSRP'),(26823,51014,'actin filament severing','P','The process in which an actin filament is broken down into smaller filaments.','2013-10-27','NSRP'),(26824,51015,'actin filament binding','F','Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.','2013-10-27','NSRP'),(26825,51016,'barbed-end actin filament capping','P','The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.','2013-10-27','NSRP'),(26826,51017,'actin filament bundle assembly','P','The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.','2013-10-27','NSRP'),(26827,51018,'protein kinase A binding','F','Interacting selectively and non-covalently with any subunit of protein kinase A.','2013-10-27','NSRP'),(26828,51019,'mitogen-activated protein kinase binding','F','Interacting selectively and non-covalently with a mitogen-activated protein kinase.','2013-10-27','NSRP'),(26829,51020,'GTPase binding','F','Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.','2013-10-27','NSRP'),(26830,51021,'GDP-dissociation inhibitor binding','F','Interacting selectively and non-covalently with a GDP-dissociation inhibitor protein.','2013-10-27','NSRP'),(26831,51022,'Rho GDP-dissociation inhibitor binding','F','Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein.','2013-10-27','NSRP'),(26832,51023,'regulation of immunoglobulin secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell.','2013-10-27','NSRP'),(26833,51024,'positive regulation of immunoglobulin secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell.','2013-10-27','NSRP'),(26834,51025,'negative regulation of immunoglobulin secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of immunoglobulins from a cell.','2013-10-27','NSRP'),(26835,51026,'chiasma assembly','P','The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.','2013-10-27','NSRP'),(26836,51027,'DNA transport','P','The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26837,51028,'mRNA transport','P','The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26838,51029,'rRNA transport','P','The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26839,51030,'snRNA transport','P','The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26840,51031,'tRNA transport','P','The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26841,51032,'nucleic acid transmembrane transporter activity','F','Catalysis of the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.','2013-10-27','NSRP'),(26842,51033,'RNA transmembrane transporter activity','F','Catalysis of the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.','2013-10-27','NSRP'),(26843,51034,'tRNA transmembrane transporter activity','F','Catalysis of the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.','2013-10-27','NSRP'),(26844,51035,'DNA transmembrane transporter activity','F','Catalysis of the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.','2013-10-27','NSRP'),(26845,51036,'regulation of endosome size','P','Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.','2013-10-27','NSRP'),(26846,51037,'regulation of transcription during meiosis','P','Any process that modulates the frequency, rate or extent of transcription during meiosis.','2013-10-27','NSRP'),(26847,51038,'negative regulation of transcription during meiosis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of transcription during meiosis.','2013-10-27','NSRP'),(26848,51039,'positive regulation of transcription during meiosis','P','Any process that activates or increases the frequency, rate or extent of transcription during meiosis.','2013-10-27','NSRP'),(26849,51040,'regulation of calcium-independent cell-cell adhesion','P','Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.','2013-10-27','NSRP'),(26850,51041,'positive regulation of calcium-independent cell-cell adhesion','P','Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.','2013-10-27','NSRP'),(26851,51042,'negative regulation of calcium-independent cell-cell adhesion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.','2013-10-27','NSRP'),(26852,51043,'regulation of membrane protein ectodomain proteolysis','P','Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).','2013-10-27','NSRP'),(26853,51044,'positive regulation of membrane protein ectodomain proteolysis','P','Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.','2013-10-27','NSRP'),(26854,51045,'negative regulation of membrane protein ectodomain proteolysis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.','2013-10-27','NSRP'),(26855,51046,'regulation of secretion','P','Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.','2013-10-27','NSRP'),(26856,51047,'positive regulation of secretion','P','Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.','2013-10-27','NSRP'),(26857,51048,'negative regulation of secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.','2013-10-27','NSRP'),(26858,51049,'regulation of transport','P','Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26859,51050,'positive regulation of transport','P','Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26860,51051,'negative regulation of transport','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(26861,51052,'regulation of DNA metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.','2013-10-27','NSRP'),(26862,51053,'negative regulation of DNA metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.','2013-10-27','NSRP'),(26863,51054,'positive regulation of DNA metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.','2013-10-27','NSRP'),(26864,51055,'negative regulation of lipid biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.','2013-10-27','NSRP'),(26865,51056,'regulation of small GTPase mediated signal transduction','P','Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.','2013-10-27','NSRP'),(26866,51057,'positive regulation of small GTPase mediated signal transduction','P','Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.','2013-10-27','NSRP'),(26867,51058,'negative regulation of small GTPase mediated signal transduction','P','Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.','2013-10-27','NSRP'),(26868,51059,'NF-kappaB binding','F','Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.','2013-10-27','NSRP'),(26869,51060,'pullulanase activity','F','Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.','2013-10-27','NSRP'),(26870,51061,'ADP reductase activity','F','Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.','2013-10-27','NSRP'),(26871,51062,'UDP reductase activity','F','Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.','2013-10-27','NSRP'),(26872,51063,'CDP reductase activity','F','Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.','2013-10-27','NSRP'),(26873,51064,'TTP reductase activity','F','Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.','2013-10-27','NSRP'),(26874,51065,'CTP reductase activity','F','Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.','2013-10-27','NSRP'),(26875,51066,'dihydrobiopterin metabolic process','P','The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.','2013-10-27','NSRP'),(26876,51067,'dihydropteridine metabolic process','P','The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.','2013-10-27','NSRP'),(26877,51068,'dihydrolipoamide metabolic process','P','The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.','2013-10-27','NSRP'),(26878,51069,'galactomannan metabolic process','P','The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.','2013-10-27','NSRP'),(26879,51070,'galactomannan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.','2013-10-27','NSRP'),(26880,51071,'4,6-pyruvylated galactose residue metabolic process','P','The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.','2013-10-27','NSRP'),(26881,51072,'4,6-pyruvylated galactose residue biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.','2013-10-27','NSRP'),(26882,51073,'adenosylcobinamide-GDP ribazoletransferase activity','F','Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.','2013-10-27','NSRP'),(26883,51074,'protein tetramerization activity','F','OBSOLETE. The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.','2013-10-27','NSRP'),(26884,51075,'S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity','F','Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.','2013-10-27','NSRP'),(26885,51077,'secondary cell septum','C','Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.','2013-10-27','NSRP'),(26886,51078,'meiotic nuclear envelope disassembly','P','The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs.','2013-10-27','NSRP'),(26887,51079,'meiosis I nuclear envelope disassembly','P','The controlled breakdown of the nuclear envelope during the first division of meiosis.','2013-10-27','NSRP'),(26888,51080,'meiosis II nuclear envelope disassembly','P','The controlled breakdown of the nuclear envelope during the second division of meiosis.','2013-10-27','NSRP'),(26889,51081,'nuclear envelope disassembly','P','The controlled breakdown of the nuclear envelope in the context of a normal process.','2013-10-27','NSRP'),(26890,51082,'unfolded protein binding','F','Interacting selectively and non-covalently with an unfolded protein.','2013-10-27','NSRP'),(26891,51083,'\'de novo\' cotranslational protein folding','P','The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.','2013-10-27','NSRP'),(26892,51084,'\'de novo\' posttranslational protein folding','P','The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.','2013-10-27','NSRP'),(26893,51085,'chaperone mediated protein folding requiring cofactor','P','The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.','2013-10-27','NSRP'),(26894,51086,'chaperone mediated protein folding independent of cofactor','P','The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.','2013-10-27','NSRP'),(26895,51087,'chaperone binding','F','Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.','2013-10-27','NSRP'),(26896,51088,'PMA-inducible membrane protein ectodomain proteolysis','P','The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist.','2013-10-27','NSRP'),(26897,51089,'constitutive protein ectodomain proteolysis','P','The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.','2013-10-27','NSRP'),(26898,51090,'regulation of sequence-specific DNA binding transcription factor activity','P','Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.','2013-10-27','NSRP'),(26899,51091,'positive regulation of sequence-specific DNA binding transcription factor activity','P','Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.','2013-10-27','NSRP'),(26900,51092,'positive regulation of NF-kappaB transcription factor activity','P','Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.','2013-10-27','NSRP'),(26901,51093,'negative regulation of developmental process','P','Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).','2013-10-27','NSRP'),(26902,51094,'positive regulation of developmental process','P','Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).','2013-10-27','NSRP'),(26903,51095,'regulation of helicase activity','P','Any process that modulates the frequency, rate or extent of helicase activity.','2013-10-27','NSRP'),(26904,51096,'positive regulation of helicase activity','P','Any process that activates or increases the activity of a helicase.','2013-10-27','NSRP'),(26905,51097,'negative regulation of helicase activity','P','Any process that stops or reduces the activity of a helicase.','2013-10-27','NSRP'),(26906,51098,'regulation of binding','P','Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.','2013-10-27','NSRP'),(26907,51099,'positive regulation of binding','P','Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.','2013-10-27','NSRP'),(26908,51100,'negative regulation of binding','P','Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.','2013-10-27','NSRP'),(26909,51101,'regulation of DNA binding','P','Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).','2013-10-27','NSRP'),(26910,51102,'DNA ligation involved in DNA recombination','P','The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.','2013-10-27','NSRP'),(26911,51103,'DNA ligation involved in DNA repair','P','The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.','2013-10-27','NSRP'),(26912,51104,'DNA ligation involved in DNA-dependent DNA replication','P','The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.','2013-10-27','NSRP'),(26913,51105,'regulation of DNA ligation','P','Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.','2013-10-27','NSRP'),(26914,51106,'positive regulation of DNA ligation','P','Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.','2013-10-27','NSRP'),(26915,51107,'negative regulation of DNA ligation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.','2013-10-27','NSRP'),(26916,51108,'carnitine-CoA ligase activity','F','Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.','2013-10-27','NSRP'),(26917,51109,'crotonobetaine-CoA ligase activity','F','Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.','2013-10-27','NSRP'),(26918,51110,'peptidyl-histidine uridylylation, to form peptidyl-1\'-(phospho-5\'-uridine)-L-histidine','P','The uridylylation of peptidyl-histidine to form peptidyl-1\'-(phospho-5\'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).','2013-10-27','NSRP'),(26919,51111,'peptidyl-histidine adenylylation','P','The adenylylation of peptidyl-histidine to form peptidyl-1\'-(phospho-5\'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3\'-(phospho-5\'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).','2013-10-27','NSRP'),(26920,51112,'peptidyl-histidine adenylylation, to form peptidyl-1\'-(phospho-5\'-adenosine)-L-histidine','P','The adenylylation of peptidyl-histidine to form peptidyl-1\'-(phospho-5\'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).','2013-10-27','NSRP'),(26921,51113,'enzyme active site formation via 1\'-(phospho-5\'-adenosine)-L-histidine','P','The transient adenylylation of peptidyl-histidine to form 1\'-(phospho-5\'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).','2013-10-27','NSRP'),(26922,51114,'peptidyl-histidine uridylylation','P','The uridylylation of peptidyl-histidine to form peptidyl-1\'-(phospho-5\'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3\'-(phospho-5\'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).','2013-10-27','NSRP'),(26923,51115,'enzyme active site formation via 1\'-(phospho-5\'-uridine)-L-histidine','P','The transient uridylylation of peptidyl-histidine to form 1\'-(phospho-5\'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).','2013-10-27','NSRP'),(26924,51116,'cobaltochelatase activity','F','Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate.','2013-10-27','NSRP'),(26925,51117,'ATPase binding','F','Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.','2013-10-27','NSRP'),(26926,51118,'glucan endo-1,3-alpha-glucosidase activity','F','Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.','2013-10-27','NSRP'),(26927,51119,'sugar transmembrane transporter activity','F','Catalysis of the transfer of a sugar from one side of the membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.','2013-10-27','NSRP'),(26928,51120,'hepoxilin A3 synthase activity','F','Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.','2013-10-27','NSRP'),(26929,51121,'hepoxilin metabolic process','P','The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.','2013-10-27','NSRP'),(26930,51122,'hepoxilin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.','2013-10-27','NSRP'),(26931,51123,'RNA polymerase II transcriptional preinitiation complex assembly','P','The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.','2013-10-27','NSRP'),(26932,51124,'synaptic growth at neuromuscular junction','P','The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.','2013-10-27','NSRP'),(26933,51125,'regulation of actin nucleation','P','Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.','2013-10-27','NSRP'),(26934,51126,'negative regulation of actin nucleation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.','2013-10-27','NSRP'),(26935,51127,'positive regulation of actin nucleation','P','Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.','2013-10-27','NSRP'),(26936,51128,'regulation of cellular component organization','P','Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.','2013-10-27','NSRP'),(26937,51129,'negative regulation of cellular component organization','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.','2013-10-27','NSRP'),(26938,51130,'positive regulation of cellular component organization','P','Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.','2013-10-27','NSRP'),(26939,51131,'chaperone-mediated protein complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.','2013-10-27','NSRP'),(26940,51132,'NK T cell activation','P','The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.','2013-10-27','NSRP'),(26941,51133,'regulation of NK T cell activation','P','Any process that modulates the frequency, rate or extent of natural killer T cell activation.','2013-10-27','NSRP'),(26942,51134,'negative regulation of NK T cell activation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.','2013-10-27','NSRP'),(26943,51135,'positive regulation of NK T cell activation','P','Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.','2013-10-27','NSRP'),(26944,51136,'regulation of NK T cell differentiation','P','Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.','2013-10-27','NSRP'),(26945,51137,'negative regulation of NK T cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.','2013-10-27','NSRP'),(26946,51138,'positive regulation of NK T cell differentiation','P','Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.','2013-10-27','NSRP'),(26947,51139,'metal ion:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).','2013-10-27','NSRP'),(26948,51140,'regulation of NK T cell proliferation','P','Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.','2013-10-27','NSRP'),(26949,51141,'negative regulation of NK T cell proliferation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.','2013-10-27','NSRP'),(26950,51142,'positive regulation of NK T cell proliferation','P','Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.','2013-10-27','NSRP'),(26951,51143,'propanediol metabolic process','P','The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.','2013-10-27','NSRP'),(26952,51144,'propanediol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.','2013-10-27','NSRP'),(26953,51145,'smooth muscle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.','2013-10-27','NSRP'),(26954,51146,'striated muscle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.','2013-10-27','NSRP'),(26955,51147,'regulation of muscle cell differentiation','P','Any process that modulates the frequency, rate or extent of muscle cell differentiation.','2013-10-27','NSRP'),(26956,51148,'negative regulation of muscle cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.','2013-10-27','NSRP'),(26957,51149,'positive regulation of muscle cell differentiation','P','Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.','2013-10-27','NSRP'),(26958,51150,'regulation of smooth muscle cell differentiation','P','Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.','2013-10-27','NSRP'),(26959,51151,'negative regulation of smooth muscle cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.','2013-10-27','NSRP'),(26960,51152,'positive regulation of smooth muscle cell differentiation','P','Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.','2013-10-27','NSRP'),(26961,51153,'regulation of striated muscle cell differentiation','P','Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.','2013-10-27','NSRP'),(26962,51154,'negative regulation of striated muscle cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.','2013-10-27','NSRP'),(26963,51155,'positive regulation of striated muscle cell differentiation','P','Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.','2013-10-27','NSRP'),(26964,51156,'glucose 6-phosphate metabolic process','P','The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.','2013-10-27','NSRP'),(26965,51157,'arabitol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.','2013-10-27','NSRP'),(26966,51158,'L-arabitol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.','2013-10-27','NSRP'),(26967,51159,'D-arabitol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.','2013-10-27','NSRP'),(26968,51160,'L-xylitol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.','2013-10-27','NSRP'),(26969,51161,'arabitol metabolic process','P','The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.','2013-10-27','NSRP'),(26970,51162,'L-arabitol metabolic process','P','The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.','2013-10-27','NSRP'),(26971,51163,'D-arabitol metabolic process','P','The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.','2013-10-27','NSRP'),(26972,51164,'L-xylitol metabolic process','P','The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.','2013-10-27','NSRP'),(26973,51165,'2,5-dihydroxypyridine metabolic process','P','The chemical reactions and pathways involving 2,5-dihydroxypyridine.','2013-10-27','NSRP'),(26974,51166,'2,5-dihydroxypyridine catabolic process','P','The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.','2013-10-27','NSRP'),(26975,51167,'xylulose 5-phosphate metabolic process','P','The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.','2013-10-27','NSRP'),(26976,51168,'nuclear export','P','The directed movement of substances out of the nucleus.','2013-10-27','NSRP'),(26977,51169,'nuclear transport','P','The directed movement of substances into, out of, or within the nucleus.','2013-10-27','NSRP'),(26978,51170,'nuclear import','P','The directed movement of substances into the nucleus.','2013-10-27','NSRP'),(26979,51171,'regulation of nitrogen compound metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.','2013-10-27','NSRP'),(26980,51172,'negative regulation of nitrogen compound metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.','2013-10-27','NSRP'),(26981,51173,'positive regulation of nitrogen compound metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.','2013-10-27','NSRP'),(26982,51174,'regulation of phosphorus metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.','2013-10-27','NSRP'),(26983,51175,'negative regulation of sulfur metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.','2013-10-27','NSRP'),(26984,51176,'positive regulation of sulfur metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.','2013-10-27','NSRP'),(26985,51177,'meiotic sister chromatid cohesion','P','The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.','2013-10-27','NSRP'),(26986,51178,'meiotic chromosome decondensation','P','The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells.','2013-10-27','NSRP'),(26987,51179,'localization','P','Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.','2013-10-27','NSRP'),(26988,51180,'vitamin transport','P','The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.','2013-10-27','NSRP'),(26989,51181,'cofactor transport','P','The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.','2013-10-27','NSRP'),(26990,51182,'coenzyme transport','P','The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.','2013-10-27','NSRP'),(26991,51183,'vitamin transporter activity','F','Enables the directed movement of vitamins into, out of or within a cell, or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.','2013-10-27','NSRP'),(26992,51184,'cofactor transporter activity','F','Enables the directed movement of a cofactor into, out of or within a cell, or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein.','2013-10-27','NSRP'),(26993,51185,'coenzyme transporter activity','F','Enables the directed movement of a coenzyme into, out of or within a cell, or between cells. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.','2013-10-27','NSRP'),(26994,51186,'cofactor metabolic process','P','The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.','2013-10-27','NSRP'),(26995,51187,'cofactor catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.','2013-10-27','NSRP'),(26996,51188,'cofactor biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.','2013-10-27','NSRP'),(26997,51189,'prosthetic group metabolic process','P','The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.','2013-10-27','NSRP'),(26998,51190,'prosthetic group catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.','2013-10-27','NSRP'),(26999,51191,'prosthetic group biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.','2013-10-27','NSRP'),(27000,51192,'prosthetic group binding','F','Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.','2013-10-27','NSRP'),(27001,51193,'regulation of cofactor metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.','2013-10-27','NSRP'),(27002,51194,'positive regulation of cofactor metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.','2013-10-27','NSRP'),(27003,51195,'negative regulation of cofactor metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.','2013-10-27','NSRP'),(27004,51196,'regulation of coenzyme metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.','2013-10-27','NSRP'),(27005,51197,'positive regulation of coenzyme metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.','2013-10-27','NSRP'),(27006,51198,'negative regulation of coenzyme metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.','2013-10-27','NSRP'),(27007,51199,'regulation of prosthetic group metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.','2013-10-27','NSRP'),(27008,51200,'positive regulation of prosthetic group metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.','2013-10-27','NSRP'),(27009,51201,'negative regulation of prosthetic group metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.','2013-10-27','NSRP'),(27010,51202,'phytochromobilin metabolic process','P','The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.','2013-10-27','NSRP'),(27011,51203,'peptidyl-aspartic acid reduction to form L-aspartyl aldehyde','P','The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.','2013-10-27','NSRP'),(27012,51204,'protein insertion into mitochondrial membrane','P','The process that results in the incorporation of a protein into a mitochondrial membrane.','2013-10-27','NSRP'),(27013,51205,'protein insertion into membrane','P','The process that results in the incorporation of a protein into a biological membrane.','2013-10-27','NSRP'),(27014,51206,'silicate metabolic process','P','The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.','2013-10-27','NSRP'),(27015,51207,'silicic acid transport','P','The directed movement of silicic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Silicic acid, Si(OH)4, is a hydrated form of silicon dioxide that occurs in nature; it is insoluble in water or acids except hydrofluoric acid.','2013-10-27','NSRP'),(27016,51208,'sequestering of calcium ion','P','The process of binding or confining calcium ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(27017,51209,'release of sequestered calcium ion into cytosol','P','The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.','2013-10-27','NSRP'),(27018,51210,'isotropic cell growth','P','The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.','2013-10-27','NSRP'),(27019,51211,'anisotropic cell growth','P','The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.','2013-10-27','NSRP'),(27020,51212,'vanadium ion binding','F','Interacting selectively and non-covalently with vanadium (V) ions.','2013-10-27','NSRP'),(27021,51213,'dioxygenase activity','F','Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.','2013-10-27','NSRP'),(27022,51214,'RNA virus induced gene silencing','P','Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.','2013-10-27','NSRP'),(27023,51215,'DNA virus induced gene silencing','P','Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.','2013-10-27','NSRP'),(27024,51216,'cartilage development','P','The process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(27025,51217,'molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)','P','The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).','2013-10-27','NSRP'),(27026,51218,'tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)','P','The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).','2013-10-27','NSRP'),(27027,51219,'phosphoprotein binding','F','Interacting selectively and non-covalently with a phosphorylated protein.','2013-10-27','NSRP'),(27028,51220,'cytoplasmic sequestering of protein','P','The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.','2013-10-27','NSRP'),(27029,51221,'tungsten incorporation into metallo-sulfur cluster','P','The incorporation of tungsten into a metallo-sulfur cluster.','2013-10-27','NSRP'),(27030,51222,'positive regulation of protein transport','P','Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(27031,51223,'regulation of protein transport','P','Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(27032,51224,'negative regulation of protein transport','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(27033,51225,'spindle assembly','P','The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.','2013-10-27','NSRP'),(27034,51228,'mitotic spindle disassembly','P','The controlled breakdown of the spindle during a mitotic cell cycle.','2013-10-27','NSRP'),(27035,51229,'meiotic spindle disassembly','P','The controlled breakdown of the spindle during a meiotic cell cycle.','2013-10-27','NSRP'),(27036,51230,'spindle disassembly','P','The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.','2013-10-27','NSRP'),(27037,51231,'spindle elongation','P','The cell cycle process in which the distance is lengthened between poles of the spindle.','2013-10-27','NSRP'),(27038,51232,'meiotic spindle elongation','P','The lengthening of the distance between poles of the spindle during a meiotic cell cycle.','2013-10-27','NSRP'),(27039,51233,'spindle midzone','C','The area in the center of the spindle where the spindle microtubules from opposite poles overlap.','2013-10-27','NSRP'),(27040,51234,'establishment of localization','P','The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.','2013-10-27','NSRP'),(27041,51235,'maintenance of location','P','Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.','2013-10-27','NSRP'),(27042,51236,'establishment of RNA localization','P','The directed movement of RNA to a specific location.','2013-10-27','NSRP'),(27043,51237,'maintenance of RNA location','P','Any process in which RNA is maintained in a location and prevented from moving elsewhere.','2013-10-27','NSRP'),(27044,51238,'sequestering of metal ion','P','The process of binding or confining metal ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(27045,51239,'regulation of multicellular organismal process','P','Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.','2013-10-27','NSRP'),(27046,51240,'positive regulation of multicellular organismal process','P','Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.','2013-10-27','NSRP'),(27047,51241,'negative regulation of multicellular organismal process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.','2013-10-27','NSRP'),(27048,51245,'negative regulation of cellular defense response','P','Any process that stops, prevents, or reduces the rate of the cellular defense response.','2013-10-27','NSRP'),(27049,51246,'regulation of protein metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.','2013-10-27','NSRP'),(27050,51247,'positive regulation of protein metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.','2013-10-27','NSRP'),(27051,51248,'negative regulation of protein metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.','2013-10-27','NSRP'),(27052,51249,'regulation of lymphocyte activation','P','Any process that modulates the frequency, rate or extent of lymphocyte activation.','2013-10-27','NSRP'),(27053,51250,'negative regulation of lymphocyte activation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.','2013-10-27','NSRP'),(27054,51251,'positive regulation of lymphocyte activation','P','Any process that activates or increases the frequency, rate or extent of lymphocyte activation.','2013-10-27','NSRP'),(27055,51252,'regulation of RNA metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.','2013-10-27','NSRP'),(27056,51253,'negative regulation of RNA metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.','2013-10-27','NSRP'),(27057,51254,'positive regulation of RNA metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.','2013-10-27','NSRP'),(27058,51255,'spindle midzone assembly','P','The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.','2013-10-27','NSRP'),(27059,51256,'spindle midzone assembly involved in mitosis','P','The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of mitosis.','2013-10-27','NSRP'),(27060,51257,'spindle midzone assembly involved in meiosis','P','The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.','2013-10-27','NSRP'),(27061,51258,'protein polymerization','P','The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.','2013-10-27','NSRP'),(27062,51259,'protein oligomerization','P','The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.','2013-10-27','NSRP'),(27063,51260,'protein homooligomerization','P','The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.','2013-10-27','NSRP'),(27064,51261,'protein depolymerization','P','The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.','2013-10-27','NSRP'),(27065,51262,'protein tetramerization','P','The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.','2013-10-27','NSRP'),(27066,51263,'microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine','P','The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain.','2013-10-27','NSRP'),(27067,51264,'mono-olein transacylation activity','F','Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.','2013-10-27','NSRP'),(27068,51265,'diolein transacylation activity','F','Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.','2013-10-27','NSRP'),(27069,51266,'sirohydrochlorin ferrochelatase activity','F','Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.','2013-10-27','NSRP'),(27070,51267,'CP2 mannose-ethanolamine phosphotransferase activity','F','Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.','2013-10-27','NSRP'),(27071,51268,'alpha-keto amide reductase activity','F','Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.','2013-10-27','NSRP'),(27072,51269,'alpha-keto ester reductase activity','F','Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.','2013-10-27','NSRP'),(27073,51270,'regulation of cellular component movement','P','Any process that modulates the frequency, rate or extent of the movement of a cellular component.','2013-10-27','NSRP'),(27074,51271,'negative regulation of cellular component movement','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.','2013-10-27','NSRP'),(27075,51272,'positive regulation of cellular component movement','P','Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.','2013-10-27','NSRP'),(27076,51273,'beta-glucan metabolic process','P','The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.','2013-10-27','NSRP'),(27077,51274,'beta-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of beta-glucans.','2013-10-27','NSRP'),(27078,51275,'beta-glucan catabolic process','P','The chemical reactions and pathways resulting in the breakdown of beta-glucans.','2013-10-27','NSRP'),(27079,51276,'chromosome organization','P','A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information.','2013-10-27','NSRP'),(27080,51278,'fungal-type cell wall polysaccharide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.','2013-10-27','NSRP'),(27081,51279,'regulation of release of sequestered calcium ion into cytosol','P','Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.','2013-10-27','NSRP'),(27082,51280,'negative regulation of release of sequestered calcium ion into cytosol','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.','2013-10-27','NSRP'),(27083,51281,'positive regulation of release of sequestered calcium ion into cytosol','P','Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.','2013-10-27','NSRP'),(27084,51282,'regulation of sequestering of calcium ion','P','Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(27085,51283,'negative regulation of sequestering of calcium ion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(27086,51284,'positive regulation of sequestering of calcium ion','P','Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(27087,51285,'cell cortex of cell tip','C','The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.','2013-10-27','NSRP'),(27088,51286,'cell tip','C','The region at either end of the longest axis of a cylindrical or elongated cell.','2013-10-27','NSRP'),(27089,51287,'NAD binding','F','Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.','2013-10-27','NSRP'),(27090,51289,'protein homotetramerization','P','The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.','2013-10-27','NSRP'),(27091,51290,'protein heterotetramerization','P','The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.','2013-10-27','NSRP'),(27092,51291,'protein heterooligomerization','P','The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.','2013-10-27','NSRP'),(27093,51292,'nuclear pore complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.','2013-10-27','NSRP'),(27094,51293,'establishment of spindle localization','P','The directed movement of the spindle to a specific location in the cell.','2013-10-27','NSRP'),(27095,51294,'establishment of spindle orientation','P','Any process that set the alignment of spindle relative to other cellular structures.','2013-10-27','NSRP'),(27096,51295,'establishment of meiotic spindle localization','P','The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.','2013-10-27','NSRP'),(27097,51296,'establishment of meiotic spindle orientation','P','Any process that set the alignment of meiotic spindle relative to other cellular structures.','2013-10-27','NSRP'),(27098,51297,'centrosome organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.','2013-10-27','NSRP'),(27099,51298,'centrosome duplication','P','The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.','2013-10-27','NSRP'),(27100,51299,'centrosome separation','P','The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.','2013-10-27','NSRP'),(27101,51300,'spindle pole body organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.','2013-10-27','NSRP'),(27102,51301,'cell division','P','The process resulting in the physical partitioning and separation of a cell into daughter cells.','2013-10-27','NSRP'),(27103,51302,'regulation of cell division','P','Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.','2013-10-27','NSRP'),(27104,51303,'establishment of chromosome localization','P','The directed movement of a chromosome to a specific location.','2013-10-27','NSRP'),(27105,51304,'chromosome separation','P','The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with untanglement of inter-sister catenation catalyzed by topoisomerase II (topo II).','2013-10-27','NSRP'),(27106,51305,'chromosome movement towards spindle pole','P','The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.','2013-10-27','NSRP'),(27107,51306,'mitotic sister chromatid separation','P','The process in which sister chromatids are physically detached from each other during mitosis.','2013-10-27','NSRP'),(27108,51307,'meiotic chromosome separation','P','The process in which chromosomes are physically detached from each other during meiosis.','2013-10-27','NSRP'),(27109,51308,'male meiosis chromosome separation','P','The process in which paired chromosomes are physically detached from each other during male meiosis.','2013-10-27','NSRP'),(27110,51309,'female meiosis chromosome separation','P','The process in which paired chromosomes are physically detached from each other during female meiosis.','2013-10-27','NSRP'),(27111,51310,'metaphase plate congression','P','The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.','2013-10-27','NSRP'),(27112,51311,'meiotic metaphase plate congression','P','The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis.','2013-10-27','NSRP'),(27113,51312,'chromosome decondensation','P','The alteration of chromosome structure from the condensed form to a relaxed disperse form.','2013-10-27','NSRP'),(27114,51313,'attachment of spindle microtubules to chromosome','P','The process in which spindle microtubules become physically associated with a chromosome.','2012-03-14','NSRP'),(27115,51314,'attachment of spindle microtubules to mitotic chromosome','P','The cell cycle process in which spindle microtubules become physically associated with a chromosome during mitosis.','2012-03-14','NSRP'),(27116,51315,'attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation','P','The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during mitosis. During mitosis, the kinetochores of sister chromosomes are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.','2013-10-27','NSRP'),(27117,51316,'attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation','P','The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation.','2013-10-27','NSRP'),(27118,51317,'attachment of spindle microtubules to meiotic chromosome','P','The cell cycle process in which spindle microtubules become physically associated with a chromosome during meiosis.','2012-03-14','NSRP'),(27119,51318,'G1 phase','P','The cell cycle \'gap\' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.','2013-10-27','NSRP'),(27120,51319,'G2 phase','P','The cell cycle \'gap\' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).','2013-10-27','NSRP'),(27121,51320,'S phase','P','The cell cycle phase, following G1, during which DNA synthesis takes place.','2013-10-27','NSRP'),(27122,51321,'meiotic cell cycle','P','Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell.','2013-10-27','NSRP'),(27123,51322,'anaphase','P','The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.','2013-10-27','NSRP'),(27124,51323,'metaphase','P','The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.','2013-10-27','NSRP'),(27125,51324,'prophase','P','The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.','2013-10-27','NSRP'),(27126,51325,'interphase','P','The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.','2013-10-27','NSRP'),(27127,51326,'telophase','P','The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.','2013-10-27','NSRP'),(27128,51327,'meiotic M phase','P','A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.','2013-10-27','NSRP'),(27129,51328,'meiotic interphase','P','The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when meiotic prophase begins. During interphase the cell readies itself for meiosis and the replication of its DNA occurs.','2013-10-27','NSRP'),(27130,51329,'mitotic interphase','P','The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.','2013-10-27','NSRP'),(27131,51330,'meiotic G1 phase','P','The cell cycle \'gap\' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.','2013-10-27','NSRP'),(27132,51331,'meiotic G2 phase','P','The cell cycle \'gap\' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.','2013-10-27','NSRP'),(27133,51332,'meiotic S phase','P','The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.','2013-10-27','NSRP'),(27134,51333,'meiotic nuclear envelope reassembly','P','The cell cycle process in which the reformation of the nuclear envelope during meiosis occurs.','2013-10-27','NSRP'),(27135,51334,'meiosis I nuclear envelope reassembly','P','The reformation of the nuclear envelope during meiosis I.','2013-10-27','NSRP'),(27136,51335,'meiosis II nuclear envelope reassembly','P','The reformation of the nuclear envelope during meiosis II.','2013-10-27','NSRP'),(27137,51336,'regulation of hydrolase activity','P','Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.','2013-10-27','NSRP'),(27138,51337,'amitosis','P','Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.','2013-10-27','NSRP'),(27139,51338,'regulation of transferase activity','P','Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.','2013-10-27','NSRP'),(27140,51339,'regulation of lyase activity','P','Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.','2013-10-27','NSRP'),(27141,51340,'regulation of ligase activity','P','Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.','2013-10-27','NSRP'),(27142,51341,'regulation of oxidoreductase activity','P','Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.','2013-10-27','NSRP'),(27143,51342,'regulation of cyclic-nucleotide phosphodiesterase activity','P','Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3\',5\'-cyclic phosphate + H2O = nucleotide 5\'-phosphate.','2013-10-27','NSRP'),(27144,51343,'positive regulation of cyclic-nucleotide phosphodiesterase activity','P','Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3\',5\'-cyclic phosphate + H2O = nucleotide 5\'-phosphate.','2013-10-27','NSRP'),(27145,51344,'negative regulation of cyclic-nucleotide phosphodiesterase activity','P','Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3\',5\'-cyclic phosphate + H2O = nucleotide 5\'-phosphate.','2013-10-27','NSRP'),(27146,51345,'positive regulation of hydrolase activity','P','Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.','2013-10-27','NSRP'),(27147,51346,'negative regulation of hydrolase activity','P','Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.','2013-10-27','NSRP'),(27148,51347,'positive regulation of transferase activity','P','Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.','2013-10-27','NSRP'),(27149,51348,'negative regulation of transferase activity','P','Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.','2013-10-27','NSRP'),(27150,51349,'positive regulation of lyase activity','P','Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.','2013-10-27','NSRP'),(27151,51350,'negative regulation of lyase activity','P','Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.','2013-10-27','NSRP'),(27152,51351,'positive regulation of ligase activity','P','Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.','2013-10-27','NSRP'),(27153,51352,'negative regulation of ligase activity','P','Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.','2013-10-27','NSRP'),(27154,51353,'positive regulation of oxidoreductase activity','P','Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.','2013-10-27','NSRP'),(27155,51354,'negative regulation of oxidoreductase activity','P','Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.','2013-10-27','NSRP'),(27156,51355,'proprioception involved in equilibrioception','P','The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.','2013-10-27','NSRP'),(27157,51356,'visual perception involved in equilibrioception','P','The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.','2013-10-27','NSRP'),(27158,51357,'peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one','P','The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.','2013-10-27','NSRP'),(27159,51358,'peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine','P','The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus.','2013-10-27','NSRP'),(27160,51359,'peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine','P','The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor.','2013-10-27','NSRP'),(27161,51360,'peptide cross-linking via L-asparagine 5-imidazolinone glycine','P','The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.','2013-10-27','NSRP'),(27162,51361,'peptide cross-linking via L-lysine 5-imidazolinone glycine','P','The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.','2013-10-27','NSRP'),(27163,51362,'peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine','P','The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species.','2013-10-27','NSRP'),(27164,51363,'peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein','P','The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.','2013-10-27','NSRP'),(27165,51364,'N-terminal peptidyl-proline N-formylation','P','The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.','2013-10-27','NSRP'),(27166,51365,'cellular response to potassium ion starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.','2013-10-27','NSRP'),(27167,51366,'protein decanoylation','P','The modification of a protein amino acid by formation of an ester or amide with decanoic acid.','2013-10-27','NSRP'),(27168,51367,'peptidyl-serine decanoylation','P','The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.','2013-10-27','NSRP'),(27169,51368,'peptidyl-threonine octanoylation','P','The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.','2013-10-27','NSRP'),(27170,51369,'peptidyl-threonine decanoylation','P','The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.','2013-10-27','NSRP'),(27171,51370,'ZASP binding','F','OBSOLETE. Interacting selectively and non-covalently with Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.','2013-10-27','NSRP'),(27172,51371,'muscle alpha-actinin binding','F','Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.','2013-10-27','NSRP'),(27173,51372,'nonmuscle alpha-actinin binding','F','Interacting selectively and non-covalently with nonmuscle isoforms of actinin. Nonmuscle alpha-actinin is found at the leading edge of motile cells, cell adhesion sites, focal contacts and along actin stress fibers in migrating cells.','2012-03-14','NSRP'),(27174,51373,'FATZ binding','F','Interacting selectively and non-covalently with a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.','2013-10-27','NSRP'),(27175,51374,'FATZ 1 binding','F','Interacting selectively and non-covalently with FATZ 1, a protein of FATZ family that is highly expressed in skeletal muscle fast fiber.','2012-03-14','NSRP'),(27176,51375,'FATZ 2 binding','F','Interacting selectively and non-covalently with FATZ 2, a protein of the FATZ family that is highly expressed in skeletal muscle fiber fast IIa and slow I and in cardiac muscle.','2012-03-14','NSRP'),(27177,51376,'FATZ 3 binding','F','Interacting selectively and non-covalently with FATZ 3, a protein of the FATZ family that is highly expressed in skeletal muscle fast fiber.','2012-03-14','NSRP'),(27178,51377,'mannose-ethanolamine phosphotransferase activity','F','Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.','2013-10-27','NSRP'),(27179,51378,'serotonin binding','F','Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.','2013-10-27','NSRP'),(27180,51379,'epinephrine binding','F','Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.','2013-10-27','NSRP'),(27181,51380,'norepinephrine binding','F','Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.','2013-10-27','NSRP'),(27182,51381,'histamine binding','F','Interacting selectively and non-covalently with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.','2013-10-27','NSRP'),(27183,51382,'kinetochore assembly','P','The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.','2013-10-27','NSRP'),(27184,51383,'kinetochore organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.','2013-10-27','NSRP'),(27185,51384,'response to glucocorticoid stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.','2013-10-27','NSRP'),(27186,51385,'response to mineralocorticoid stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.','2013-10-27','NSRP'),(27187,51386,'regulation of neurotrophin TRK receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.','2013-10-27','NSRP'),(27188,51387,'negative regulation of neurotrophin TRK receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.','2013-10-27','NSRP'),(27189,51388,'positive regulation of neurotrophin TRK receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.','2013-10-27','NSRP'),(27190,51389,'inactivation of MAPKK activity','P','Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK).','2013-10-27','NSRP'),(27191,51390,'inactivation of MAPKKK activity','P','Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK).','2013-10-27','NSRP'),(27192,51391,'tRNA acetylation','P','The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.','2013-10-27','NSRP'),(27193,51392,'tRNA N-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.','2013-10-27','NSRP'),(27194,51393,'alpha-actinin binding','F','Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.','2013-10-27','NSRP'),(27195,51394,'regulation of nerve growth factor receptor activity','P','Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.','2013-10-27','NSRP'),(27196,51395,'negative regulation of nerve growth factor receptor activity','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.','2013-10-27','NSRP'),(27197,51396,'positive regulation of nerve growth factor receptor activity','P','Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.','2013-10-27','NSRP'),(27198,51397,'N-terminal basic amino acid aminopeptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of basic amino acid residues at the N-terminal of an oligopeptide or polypeptide chain.','2013-10-27','NSRP'),(27199,51398,'N-terminal lysine aminopeptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of a lysine residue from the N-terminal of an oligopeptide or polypeptide chain.','2013-10-27','NSRP'),(27200,51399,'N-terminal arginine aminopeptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain.','2013-10-27','NSRP'),(27201,51400,'BH domain binding','F','Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.','2013-10-27','NSRP'),(27202,51401,'CH domain binding','F','Interacting selectively and non-covalently with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.','2013-10-27','NSRP'),(27203,51402,'neuron apoptotic process','P','Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.','2013-10-27','NSRP'),(27204,51403,'stress-activated MAPK cascade','P','A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.','2013-10-27','NSRP'),(27205,51404,'clostripain activity','F','OBSOLETE. Catalysis of the cleavage of Arg-Xaa bonds.','2013-10-27','NSRP'),(27206,51405,'microbial collagenase activity','F','OBSOLETE. Catalysis of the digestion of native collagen in the triple helical region at Xaa-Gly bonds.','2013-10-27','NSRP'),(27207,51406,'beta-actinin binding','F','Interacting selectively and non-covalently with beta-actinin, a heterodimeric actin-binding protein which caps the barbed end of actin filaments and nucleates actin polymerization in a calcium-independent manner. In myofibrils it is localized in the Z-lines.','2012-03-14','NSRP'),(27208,51407,'glycerone phosphate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).','2013-10-27','NSRP'),(27209,51408,'glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).','2013-10-27','NSRP'),(27210,51409,'response to nitrosative stress','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.','2013-10-27','NSRP'),(27211,51410,'detoxification of nitrogen compound','P','Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.','2013-10-27','NSRP'),(27212,51411,'ALP binding','F','OBSOLETE. Interacting selectively and non-covalently wih ALP, actinin-associated LIM protein of the Z band. ALP is a PDZ/LIM domain protein found in the Z band.','2013-10-27','NSRP'),(27213,51412,'response to corticosterone stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.','2013-10-27','NSRP'),(27214,51413,'response to cortisone stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.','2013-10-27','NSRP'),(27215,51414,'response to cortisol stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.','2013-10-27','NSRP'),(27216,51415,'interphase microtubule nucleation by interphase microtubule organizing center','P','The \'de novo\' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.','2013-10-27','NSRP'),