(7848,9784,'transmembrane receptor histidine kinase activity','F','Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.','2013-10-27','NSRP'),(7849,9785,'blue light signaling pathway','P','The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.','2013-10-27','NSRP'),(7850,9786,'regulation of asymmetric cell division','P','Any process that modulates the frequency, rate or extent of asymmetric cell division.','2013-10-27','NSRP'),(7851,9787,'regulation of abscisic acid mediated signaling pathway','P','Any process that modulates the frequency, rate or extent of signal transduction mediated by abscisic acid.','2013-10-27','NSRP'),(7852,9788,'negative regulation of abscisic acid mediated signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by abscisic acid.','2013-10-27','NSRP'),(7853,9789,'positive regulation of abscisic acid mediated signaling pathway','P','Any process that activates or increases the frequency, rate or extent of abscisic acid mediated signal transduction.','2013-10-27','NSRP'),(7854,9790,'embryo development','P','The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.','2013-10-27','NSRP'),(7855,9791,'post-embryonic development','P','The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.','2013-10-27','NSRP'),(7856,9792,'embryo development ending in birth or egg hatching','P','The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.','2013-10-27','NSRP'),(7857,9793,'embryo development ending in seed dormancy','P','The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7858,9794,'regulation of mitotic cell cycle, embryonic','P','Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.','2013-10-27','NSRP'),(7859,9798,'axis specification','P','The establishment, maintenance and elaboration of a pattern along a line or around a point.','2013-10-27','NSRP'),(7860,9799,'specification of symmetry','P','The establishment of an organism\'s body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.','2013-10-27','NSRP'),(7861,9800,'cinnamic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.','2013-10-27','NSRP'),(7862,9801,'cinnamic acid ester metabolic process','P','The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.','2013-10-27','NSRP'),(7863,9802,'cinnamic acid ester biosynthetic process','P','The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.','2013-10-27','NSRP'),(7864,9803,'cinnamic acid metabolic process','P','The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.','2013-10-27','NSRP'),(7865,9804,'coumarin metabolic process','P','The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.','2013-10-27','NSRP'),(7866,9805,'coumarin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.','2013-10-27','NSRP'),(7867,9806,'lignan metabolic process','P','The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.','2013-10-27','NSRP'),(7868,9807,'lignan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.','2013-10-27','NSRP'),(7869,9808,'lignin metabolic process','P','The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.','2013-10-27','NSRP'),(7870,9809,'lignin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.','2013-10-27','NSRP'),(7871,9810,'stilbene metabolic process','P','The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA.','2013-10-27','NSRP'),(7872,9811,'stilbene biosynthetic process','P','The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.','2013-10-27','NSRP'),(7873,9812,'flavonoid metabolic process','P','The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.','2013-10-27','NSRP'),(7874,9813,'flavonoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.','2013-10-27','NSRP'),(7875,9814,'defense response, incompatible interaction','P','A response of a plant to a pathogenic agent that prevents the occurrence or spread of disease.','2013-10-27','NSRP'),(7876,9815,'1-aminocyclopropane-1-carboxylate oxidase activity','F','Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.','2013-10-27','NSRP'),(7877,9816,'defense response to bacterium, incompatible interaction','P','A response of an organism to a bacterium that prevents the occurrence or spread of disease.','2013-10-27','NSRP'),(7878,9817,'defense response to fungus, incompatible interaction','P','A response of an organism to a fungus that prevents the occurrence or spread of disease.','2013-10-27','NSRP'),(7879,9818,'defense response to protozoan, incompatible interaction','P','A response of an organism to a protozoan that prevents the occurrence or spread of disease.','2013-10-27','NSRP'),(7880,9819,'drought recovery','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.','2013-10-27','NSRP'),(7881,9820,'alkaloid metabolic process','P','The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).','2013-10-27','NSRP'),(7882,9821,'alkaloid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).','2013-10-27','NSRP'),(7883,9822,'alkaloid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).','2013-10-27','NSRP'),(7884,9823,'cytokinin catabolic process','P','The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.','2013-10-27','NSRP'),(7885,9824,'AMP dimethylallyltransferase activity','F','Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5\'-phosphate + diphosphate.','2013-10-27','NSRP'),(7886,9825,'multidimensional cell growth','P','The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.','2013-10-27','NSRP'),(7887,9826,'unidimensional cell growth','P','The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.','2013-10-27','NSRP'),(7888,9827,'plant-type cell wall modification','P','The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7889,9828,'plant-type cell wall loosening','P','The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7890,9829,'cell wall modification involved in fruit ripening','P','The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.','2013-10-27','NSRP'),(7891,9830,'cell wall modification involved in abscission','P','A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.','2013-10-27','NSRP'),(7892,9831,'plant-type cell wall modification involved in multidimensional cell growth','P','The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7893,9832,'plant-type cell wall biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7894,9833,'primary cell wall biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7895,9834,'secondary cell wall biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7896,9835,'fruit ripening','P','An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.','2013-10-27','NSRP'),(7897,9836,'fruit ripening, climacteric','P','A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.','2013-10-27','NSRP'),(7898,9837,'fruit ripening, non-climacteric','P','A fruit ripening process that does not involve a respiratory burst.','2013-10-27','NSRP'),(7899,9838,'abscission','P','The controlled shedding of a body part.','2013-10-27','NSRP'),(7900,9839,'SCF complex substrate recognition subunit','C','OBSOLETE. The portion of the SCF ubiquitin ligase complex that contains sites required for recognition (and recruitment) of the substrate to the complex.','2013-10-27','NSRP'),(7901,9840,'chloroplastic endopeptidase Clp complex','C','A Clp endopeptidase complex located in the chloroplast.','2013-10-27','NSRP'),(7902,9841,'mitochondrial endopeptidase Clp complex','C','A Clp endopeptidase complex located in the mitochondrion.','2013-10-27','NSRP'),(7903,9842,'cyanelle','C','A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.','2013-10-27','NSRP'),(7904,9843,'cyanelle thylakoid','C','A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.','2013-10-27','NSRP'),(7905,9844,'germination','P','OBSOLETE. The physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.','2013-10-27','NSRP'),(7906,9845,'seed germination','P','The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.','2013-10-27','NSRP'),(7907,9846,'pollen germination','P','The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.','2013-10-27','NSRP'),(7908,9847,'spore germination','P','The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).','2013-10-27','NSRP'),(7909,9848,'indoleacetic acid biosynthetic process via tryptophan','P','The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan.','2013-10-27','NSRP'),(7910,9849,'tryptophan-independent indoleacetic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan.','2013-10-27','NSRP'),(7911,9850,'auxin metabolic process','P','The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(7912,9851,'auxin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(7913,9852,'auxin catabolic process','P','The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(7914,9853,'photorespiration','P','A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.','2013-10-27','NSRP'),(7915,9854,'oxidative photosynthetic carbon pathway','P','The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).','2013-10-27','NSRP'),(7916,9855,'determination of bilateral symmetry','P','The establishment of an organism\'s body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.','2013-10-27','NSRP'),(7917,9856,'pollination','P','The cascade of biological processes occurring in plants beginning when the pollen lands on the stigma and continuing up to, but not including, fertilization, as defined by sperm-central cell fusion.','2013-10-27','NSRP'),(7918,9858,'compatible pollen-pistil interaction','P','OBSOLETE. An interaction between a pollen grain and pistil that results in unimpeded growth of the pollen tube through the stigma and style.','2013-10-27','NSRP'),(7919,9859,'pollen hydration','P','The process in which water is taken up by pollen.','2013-10-27','NSRP'),(7920,9860,'pollen tube growth','P','Growth of pollen via tip extension of the intine wall.','2013-10-27','NSRP'),(7921,9861,'jasmonic acid and ethylene-dependent systemic resistance','P','The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.','2013-10-27','NSRP'),(7922,9862,'systemic acquired resistance, salicylic acid mediated signaling pathway','P','The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.','2013-10-27','NSRP'),(7923,9863,'salicylic acid mediated signaling pathway','P','A series of molecular signals mediated by salicylic acid.','2013-10-27','NSRP'),(7924,9864,'induced systemic resistance, jasmonic acid mediated signaling pathway','P','The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.','2013-10-27','NSRP'),(7925,9865,'pollen tube adhesion','P','The process in which the pollen tube adheres to cells of the stigma and style.','2013-10-27','NSRP'),(7926,9866,'induced systemic resistance, ethylene mediated signaling pathway','P','The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.','2013-10-27','NSRP'),(7927,9867,'jasmonic acid mediated signaling pathway','P','A series of molecular signals mediated by jasmonic acid.','2013-10-27','NSRP'),(7928,9868,'jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway','P','The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.','2013-10-27','NSRP'),(7929,9869,'incompatible pollen-pistil interaction','P','OBSOLETE. An interaction between a pollen grain and pistil that results in inhibition of pollen germination/growth.','2013-10-27','NSRP'),(7930,9870,'defense response signaling pathway, resistance gene-dependent','P','A series of molecular signals that depends upon R-genes and is activated during defense response.','2013-10-27','NSRP'),(7931,9871,'jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway','P','The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.','2013-10-27','NSRP'),(7932,9872,'gametophytic self-incompatibility','P','OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.','2013-10-27','NSRP'),(7933,9873,'ethylene mediated signaling pathway','P','A series of molecular signals mediated by ethylene (ethene).','2013-10-27','NSRP'),(7934,9874,'sporophytic self-incompatibility','P','OBSOLETE. A mechanism that functions to prevent self-fertilization in flowering plants that is determined by the diploid genotype of the parent plant. In sporophytic incompatibility the pollen does not germinate, consequently fertilization does not take place.','2013-10-27','NSRP'),(7935,9875,'pollen-pistil interaction','P','The interaction between a pollen grain and pistil.','2013-10-27','NSRP'),(7936,9876,'pollen adhesion','P','The process in which pollen deposited on the stigma adheres to cells of the stigma.','2013-10-27','NSRP'),(7937,9877,'nodulation','P','The formation of nitrogen-fixing root nodules on plant roots.','2013-10-27','NSRP'),(7938,9878,'nodule morphogenesis','P','The process in which the anatomical structures of the nodule are generated and organized.','2013-10-27','NSRP'),(7939,9879,'determination of radial symmetry','P','The establishment of an organism\'s body plan or a part of an organism such that it is symmetric around a central axis.','2013-10-27','NSRP'),(7940,9880,'embryonic pattern specification','P','The process that results in the patterns of cell differentiation that will arise in an embryo.','2013-10-27','NSRP'),(7941,9881,'photoreceptor activity','F','The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.','2013-10-27','NSRP'),(7942,9882,'blue light photoreceptor activity','F','The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.','2013-10-27','NSRP'),(7943,9883,'red or far-red light photoreceptor activity','F','The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.','2013-10-27','NSRP'),(7944,9884,'cytokinin receptor activity','F','Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(7945,9885,'transmembrane histidine kinase cytokinin receptor activity','F','Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.','2013-10-27','NSRP'),(7946,9886,'post-embryonic morphogenesis','P','The process, occurring after embryonic development, by which anatomical structures are generated and organized.','2013-10-27','NSRP'),(7947,9887,'organ morphogenesis','P','Morphogenesis of an organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.','2013-10-27','NSRP'),(7948,9888,'tissue development','P','The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.','2013-10-27','NSRP'),(7949,9889,'regulation of biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.','2013-10-27','NSRP'),(7950,9890,'negative regulation of biosynthetic process','P','Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.','2013-10-27','NSRP'),(7951,9891,'positive regulation of biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.','2013-10-27','NSRP'),(7952,9892,'negative regulation of metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.','2013-10-27','NSRP'),(7953,9893,'positive regulation of metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.','2013-10-27','NSRP'),(7954,9894,'regulation of catabolic process','P','Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.','2013-10-27','NSRP'),(7955,9895,'negative regulation of catabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.','2013-10-27','NSRP'),(7956,9896,'positive regulation of catabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.','2013-10-27','NSRP'),(7957,9897,'external side of plasma membrane','C','The side (leaflet) of the plasma membrane that is opposite to the side that faces the cytoplasm.','2013-10-27','NSRP'),(7958,9898,'internal side of plasma membrane','C','The side (leaflet) of the plasma membrane that faces the cytoplasm.','2013-10-27','NSRP'),(7959,9899,'ent-kaurene synthase activity','F','Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.','2013-10-27','NSRP'),(7960,9900,'dehiscence','P','The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.','2013-10-27','NSRP'),(7961,9901,'anther dehiscence','P','The dehiscence of an anther to release the pollen grains contained within it.','2013-10-27','NSRP'),(7962,9902,'chloroplast relocation','P','The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.','2013-10-27','NSRP'),(7963,9903,'chloroplast avoidance movement','P','The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.','2013-10-27','NSRP'),(7964,9904,'chloroplast accumulation movement','P','The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.','2013-10-27','NSRP'),(7965,9905,'ent-copalyl diphosphate synthase activity','F','Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.','2013-10-27','NSRP'),(7966,9906,'response to photoperiod, blue light','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.','2013-10-27','NSRP'),(7967,9907,'response to photoperiod, red light','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.','2013-10-27','NSRP'),(7968,9908,'flower development','P','The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.','2013-10-27','NSRP'),(7969,9909,'regulation of flower development','P','Any process that modulates the frequency, rate or extent of flower development.','2013-10-27','NSRP'),(7970,9910,'negative regulation of flower development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.','2013-10-27','NSRP'),(7971,9911,'positive regulation of flower development','P','Any process that activates or increases the frequency, rate or extent of flower development.','2013-10-27','NSRP'),(7972,9912,'auditory receptor cell fate commitment','P','The process in which the cellular identity of auditory hair cells is acquired and determined.','2013-10-27','NSRP'),(7973,9913,'epidermal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.','2013-10-27','NSRP'),(7974,9914,'hormone transport','P','The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(7975,9915,'phloem sucrose loading','P','The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.','2013-10-27','NSRP'),(7976,9916,'alternative oxidase activity','F','Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.','2013-10-27','NSRP'),(7977,9917,'sterol 5-alpha reductase activity','F','Catalysis of the removal of a C-5 double bond in the B ring of a sterol.','2013-10-27','NSRP'),(7978,9918,'sterol delta7 reductase activity','F','Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.','2013-10-27','NSRP'),(7979,9919,'cytokinesis (sensu Viridiplantae)','P','OBSOLETE. The division of a cell into two daughter cells with cell walls.','2013-10-27','NSRP'),(7980,9920,'cell plate formation involved in plant-type cell wall biogenesis','P','The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(7981,9921,'auxin efflux carrier complex','C','The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.','2013-10-27','NSRP'),(7982,9922,'fatty acid elongase activity','F','Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).','2013-10-27','NSRP'),(7983,9923,'fatty acid elongase complex','C','A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids.','2013-10-27','NSRP'),(7984,9924,'octadecanal decarbonylase activity','F','Catalysis of the reaction: octadecanal = heptadecane + CO.','2013-10-27','NSRP'),(7985,9925,'basal plasma membrane','C','The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.','2013-10-27','NSRP'),(7986,9926,'auxin polar transport','P','The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.','2013-10-27','NSRP'),(7987,9927,'histidine phosphotransfer kinase activity','F','Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.','2013-10-27','NSRP'),(7988,9930,'longitudinal side of cell surface','C','The side of the cell parallel to the zygotic axis.','2013-10-27','NSRP'),(7989,9931,'calcium-dependent protein serine/threonine kinase activity','F','Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.','2013-10-27','NSRP'),(7990,9932,'cell tip growth','P','Growth that occurs specifically at the tip of a cell.','2013-10-27','NSRP'),(7991,9933,'meristem structural organization','P','Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.','2013-10-27','NSRP'),(7992,9934,'regulation of meristem structural organization','P','Any process that modulates the frequency, rate or extent of meristem organization.','2013-10-27','NSRP'),(7993,9935,'nutrient import','P','OBSOLETE. The directed movement of nutrients into a cell or organelle.','2013-10-27','NSRP'),(7994,9936,'expansin','F','OBSOLETE. A group of proteins located within the cell walls of plants, both dicots and grasses, that play an essential role in loosening cell walls during cell growth. They are hydrophobic, non glycosylated proteins of about 30kDa.','2013-10-27','NSRP'),(7995,9937,'regulation of gibberellic acid mediated signaling pathway','P','Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.','2013-10-27','NSRP'),(7996,9938,'negative regulation of gibberellic acid mediated signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.','2013-10-27','NSRP'),(7997,9939,'positive regulation of gibberellic acid mediated signaling pathway','P','Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.','2013-10-27','NSRP'),(7998,9940,'amino-terminal vacuolar sorting propeptide binding','F','Interacting selectively and non-covalently with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.','2013-10-27','NSRP'),(7999,9941,'chloroplast envelope','C','The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.','2013-10-27','NSRP'),(8000,9942,'longitudinal axis specification','P','The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.','2013-10-27','NSRP'),(8001,9943,'adaxial/abaxial axis specification','P','The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.','2013-10-27','NSRP'),(8002,9944,'polarity specification of adaxial/abaxial axis','P','The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.','2013-10-27','NSRP'),(8003,9945,'radial axis specification','P','The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.','2013-10-27','NSRP'),(8004,9946,'proximal/distal axis specification','P','The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).','2013-10-27','NSRP'),(8005,9947,'centrolateral axis specification','P','The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.','2013-10-27','NSRP'),(8006,9948,'anterior/posterior axis specification','P','The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.','2013-10-27','NSRP'),(8007,9949,'polarity specification of anterior/posterior axis','P','Any process resulting in the establishment of polarity along the anterior/posterior axis.','2013-10-27','NSRP'),(8008,9950,'dorsal/ventral axis specification','P','The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.','2013-10-27','NSRP'),(8009,9951,'polarity specification of dorsal/ventral axis','P','Any process resulting in the establishment of polarity along the dorsal/ventral axis.','2013-10-27','NSRP'),(8010,9952,'anterior/posterior pattern specification','P','The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.','2013-10-27','NSRP'),(8011,9953,'dorsal/ventral pattern formation','P','The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.','2013-10-27','NSRP'),(8012,9954,'proximal/distal pattern formation','P','The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).','2013-10-27','NSRP'),(8013,9955,'adaxial/abaxial pattern specification','P','The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.','2013-10-27','NSRP'),(8014,9956,'radial pattern formation','P','The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.','2013-10-27','NSRP'),(8015,9957,'epidermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(8016,9958,'positive gravitropism','P','The orientation of plant parts towards gravity.','2013-10-27','NSRP'),(8017,9959,'negative gravitropism','P','The orientation of plant parts away from gravity.','2013-10-27','NSRP'),(8018,9960,'endosperm development','P','The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.','2013-10-27','NSRP'),(8019,9961,'response to 1-aminocyclopropane-1-carboxylic acid','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.','2013-10-27','NSRP'),(8020,9962,'regulation of flavonoid biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.','2013-10-27','NSRP'),(8021,9963,'positive regulation of flavonoid biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.','2013-10-27','NSRP'),(8022,9964,'negative regulation of flavonoid biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.','2013-10-27','NSRP'),(8023,9965,'leaf morphogenesis','P','The process in which the anatomical structures of the leaf are generated and organized.','2013-10-27','NSRP'),(8024,9966,'regulation of signal transduction','P','Any process that modulates the frequency, rate or extent of signal transduction.','2013-10-27','NSRP'),(8025,9967,'positive regulation of signal transduction','P','Any process that activates or increases the frequency, rate or extent of signal transduction.','2013-10-27','NSRP'),(8026,9968,'negative regulation of signal transduction','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.','2013-10-27','NSRP'),(8027,9969,'xyloglucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.','2013-10-27','NSRP'),(8028,9970,'cellular response to sulfate starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.','2013-10-27','NSRP'),(8029,9971,'anastral spindle assembly involved in male meiosis','P','The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.','2013-10-27','NSRP'),(8030,9972,'cytidine deamination','P','The removal of amino group in the presence of water.','2013-10-27','NSRP'),(8031,9973,'adenylyl-sulfate reductase activity','F','Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.','2013-10-27','NSRP'),(8032,9974,'zeinoxanthin epsilon hydroxylase activity','F','Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.','2013-10-27','NSRP'),(8033,9975,'cyclase activity','F','Catalysis of a ring closure reaction.','2013-10-27','NSRP'),(8034,9976,'tocopherol cyclase activity','F','Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).','2013-10-27','NSRP'),(8035,9977,'proton motive force dependent protein transmembrane transporter activity','F','Catalysis of the transfer of proteins from one side of the membrane to the other. Transportation is dependent on pH gradient across the membrane.','2013-10-27','NSRP'),(8036,9978,'allene oxide synthase activity','F','Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.','2013-10-27','NSRP'),(8037,9979,'16:0 monogalactosyldiacylglycerol desaturase activity','F','Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.','2013-10-27','NSRP'),(8038,9980,'glutamate carboxypeptidase activity','F','OBSOLETE. Catalysis of the release of C-terminal glutamate residues from a wide range of N-acylating groups, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups.','2013-10-27','NSRP'),(8039,9982,'pseudouridine synthase activity','F','Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1\'-N-1 glycosidic bond of uridine in RNA to a C1\'-C5.','2013-10-27','NSRP'),(8040,9983,'tyrosine aminopeptidase activity','F','OBSOLETE. Catalysis of the release of N-terminal tyrosine from a peptide.','2013-10-27','NSRP'),(8041,9984,'adenylate forming enzyme activity','F','OBSOLETE. Catalysis of the reaction: substrate + ATP = substrate-AMP + diphosphate.','2013-10-27','NSRP'),(8042,9985,'dihydroflavonol(thiole) lyase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(8043,9986,'cell surface','C','The external part of the cell wall and/or plasma membrane.','2013-10-27','NSRP'),(8044,9987,'cellular process','P','Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.','2013-10-27','NSRP'),(8045,9988,'cell-cell recognition','P','Cell recognition between cells, usually involving the formation of specialized cell junctions.','2013-10-27','NSRP'),(8046,9989,'cell-matrix recognition','P','Cell recognition that involves the interaction of the cell with the extracellular matrix.','2013-10-27','NSRP'),(8047,9990,'contact guidance','P','Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.','2013-10-27','NSRP'),(8048,9991,'response to extracellular stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.','2013-10-27','NSRP'),(8049,9992,'cellular water homeostasis','P','Any process involved in the maintenance of an internal steady state of water within a cell.','2013-10-27','NSRP'),(8050,9994,'oocyte differentiation','P','The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.','2013-10-27','NSRP'),(8051,9995,'soluble molecule recognition','P','The recognition of soluble molecules in the environment.','2013-10-27','NSRP'),(8052,9996,'negative regulation of cell fate specification','P','Any process that restricts, stops or prevents a cell from adopting a specific cell fate.','2013-10-27','NSRP'),(8053,9997,'negative regulation of cardioblast cell fate specification','P','Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.','2013-10-27','NSRP'),(8054,9998,'negative regulation of retinal cone cell fate specification','P','Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.','2013-10-27','NSRP'),(8055,9999,'negative regulation of auditory receptor cell fate specification','P','Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.','2013-10-27','NSRP'),(8056,10001,'glial cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.','2013-10-27','NSRP'),(8057,10002,'cardioblast differentiation','P','The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.','2013-10-27','NSRP'),(8058,10004,'gastrulation involving germ band extension','P','A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.','2013-10-27','NSRP'),(8059,10005,'cortical microtubule, transverse to long axis','C','Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.','2013-10-27','NSRP'),(8060,10006,'Toc complex','C','Protein translocon complex at the chloroplast outer membrane.','2013-10-27','NSRP'),(8061,10007,'magnesium chelatase complex','C','A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.','2013-10-27','NSRP'),(8062,10008,'endosome membrane','C','The lipid bilayer surrounding an endosome.','2013-10-27','NSRP'),(8063,10009,'external side of endosome membrane','C','The external (cytoplasmic) face of an endosome membrane.','2013-10-27','NSRP'),(8064,10011,'auxin binding','F','Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(8065,10012,'steroid 22-alpha hydroxylase activity','F','Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.','2013-10-27','NSRP'),(8066,10013,'N-1-naphthylphthalamic acid binding','F','Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor.','2013-10-27','NSRP'),(8067,10014,'meristem initiation','P','Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.','2013-10-27','NSRP'),(8068,10015,'root morphogenesis','P','The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.','2013-10-27','NSRP'),(8069,10016,'shoot system morphogenesis','P','The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.','2013-10-27','NSRP'),(8070,10017,'red or far-red light signaling pathway','P','The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.','2013-10-27','NSRP'),(8071,10018,'far-red light signaling pathway','P','The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.','2013-10-27','NSRP'),(8072,10019,'chloroplast-nucleus signaling pathway','P','The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.','2013-10-27','NSRP'),(8073,10020,'chloroplast fission','P','The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.','2013-10-27','NSRP'),(8074,10021,'amylopectin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.','2013-10-27','NSRP'),(8075,10022,'meristem determinacy','P','The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).','2013-10-27','NSRP'),(8076,10023,'proanthocyanidin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of proanthocyanidin.','2013-10-27','NSRP'),(8077,10024,'phytochromobilin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.','2013-10-27','NSRP'),(8078,10025,'wax biosynthetic process','P','The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.','2013-10-27','NSRP'),(8079,10026,'trichome differentiation','P','The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8080,10027,'thylakoid membrane organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.','2013-10-27','NSRP'),(8081,10028,'xanthophyll cycle','P','A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.','2013-10-27','NSRP'),(8082,10029,'regulation of seed germination','P','Any process that modulates the frequency, rate or extent of seed germination.','2013-10-27','NSRP'),(8083,10030,'positive regulation of seed germination','P','Any process that activates or increase the rate of seed germination.','2013-10-27','NSRP'),(8084,10031,'circumnutation','P','The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.','2013-10-27','NSRP'),(8085,10032,'meiotic chromosome condensation','P','Compaction of chromatin structure prior to meiosis in eukaryotic cells.','2013-10-27','NSRP'),(8086,10033,'response to organic substance','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.','2013-10-27','NSRP'),(8087,10034,'response to acetate','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.','2013-10-27','NSRP'),(8088,10035,'response to inorganic substance','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.','2013-10-27','NSRP'),(8089,10036,'response to boron-containing substance','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.','2013-10-27','NSRP'),(8090,10037,'response to carbon dioxide','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.','2013-10-27','NSRP'),(8091,10038,'response to metal ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.','2013-10-27','NSRP'),(8092,10039,'response to iron ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.','2013-10-27','NSRP'),(8093,10040,'response to iron(II) ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.','2013-10-27','NSRP'),(8094,10041,'response to iron(III) ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.','2013-10-27','NSRP'),(8095,10042,'response to manganese ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.','2013-10-27','NSRP'),(8096,10043,'response to zinc ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.','2013-10-27','NSRP'),(8097,10044,'response to aluminum ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.','2013-10-27','NSRP'),(8098,10045,'response to nickel cation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.','2013-10-27','NSRP'),(8099,10046,'response to mycotoxin','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.','2013-10-27','NSRP'),(8100,10047,'fruit dehiscence','P','The process leading to the spontaneous opening of the fruit permitting the escape of seeds.','2013-10-27','NSRP'),(8101,10048,'vernalization response','P','The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.','2013-10-27','NSRP'),(8102,10049,'acquisition of reproductive competence','P','The process in which a plant acquires the ability to respond to a floral inductive signal.','2013-10-27','NSRP'),(8103,10050,'vegetative phase change','P','Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.','2013-10-27','NSRP'),(8104,10051,'xylem and phloem pattern formation','P','The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8105,10052,'guard cell differentiation','P','The process in which a guard mother cell acquires the specialized features of a guard cell.','2013-10-27','NSRP'),(8106,10053,'root epidermal cell differentiation','P','The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.','2013-10-27','NSRP'),(8107,10054,'trichoblast differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.','2013-10-27','NSRP'),(8108,10055,'atrichoblast differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.','2013-10-27','NSRP'),(8109,10056,'atrichoblast fate specification','P','The process involved in the specification of an atrichoblast.','2013-10-27','NSRP'),(8110,10057,'trichoblast fate specification','P','The process involved in the specification of a trichoblast.','2013-10-27','NSRP'),(8111,10058,'regulation of atrichoblast fate specification','P','Any process that modulates atrichoblast fate specification.','2013-10-27','NSRP'),(8112,10059,'positive regulation of atrichoblast fate specification','P','Any process that induces or promotes atrichoblast fate specification.','2013-10-27','NSRP'),(8113,10060,'negative regulation of atrichoblast fate specification','P','Any process that suppresses atrichoblast fate specification.','2013-10-27','NSRP'),(8114,10061,'regulation of trichoblast fate specification','P','Any process that modulates trichoblast fate specification.','2013-10-27','NSRP'),(8115,10062,'negative regulation of trichoblast fate specification','P','Any process that suppresses trichoblast fate specification.','2013-10-27','NSRP'),(8116,10063,'positive regulation of trichoblast fate specification','P','Any process that induces or promotes trichoblast fate specification.','2013-10-27','NSRP'),(8117,10064,'embryonic shoot morphogenesis','P','The process in which the anatomical structures of embryonic shoot are generated and organized.','2013-10-27','NSRP'),(8118,10065,'primary meristem tissue development','P','The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.','2013-10-27','NSRP'),(8119,10066,'ground meristem histogenesis','P','The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.','2013-10-27','NSRP'),(8120,10067,'procambium histogenesis','P','The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.','2013-10-27','NSRP'),(8121,10068,'protoderm histogenesis','P','The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.','2013-10-27','NSRP'),(8122,10069,'zygote asymmetric cytokinesis in embryo sac','P','The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8123,10070,'zygote asymmetric cell division','P','The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.','2013-10-27','NSRP'),(8124,10071,'root meristem specification','P','The specification of a meristem which will give rise to a primary or lateral root.','2013-10-27','NSRP'),(8125,10072,'primary shoot apical meristem specification','P','The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.','2013-10-27','NSRP'),(8126,10073,'meristem maintenance','P','Any process involved in maintaining the identity, size and shape of a meristem.','2013-10-27','NSRP'),(8127,10074,'maintenance of meristem identity','P','The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8128,10075,'regulation of meristem growth','P','Any process involved in maintaining the size and shape of a meristem.','2013-10-27','NSRP'),(8129,10076,'maintenance of floral meristem identity','P','The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8130,10077,'maintenance of inflorescence meristem identity','P','The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8131,10078,'maintenance of root meristem identity','P','The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8132,10079,'maintenance of vegetative meristem identity','P','The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8133,10080,'regulation of floral meristem growth','P','Any process involved in maintaining the size and shape of a floral meristem.','2013-10-27','NSRP'),(8134,10081,'regulation of inflorescence meristem growth','P','Any process involved in maintaining the size and shape of an inflorescence meristem.','2013-10-27','NSRP'),(8135,10082,'regulation of root meristem growth','P','Any process involved in maintaining the size and shape of a root meristem.','2013-10-27','NSRP'),(8136,10083,'regulation of vegetative meristem growth','P','Any process involved in maintaining the size and shape of a vegetative meristem.','2013-10-27','NSRP'),(8137,10084,'specification of organ axis polarity','P','The process in which the polarity of an organ axis is specified.','2013-10-27','NSRP'),(8138,10085,'polarity specification of proximal/distal axis','P','Any process resulting in the establishment of polarity along the proximal/distal axis.','2013-10-27','NSRP'),(8139,10086,'embryonic root morphogenesis','P','The process in which the anatomical structures of the embryonic root are generated and organized.','2013-10-27','NSRP'),(8140,10087,'phloem or xylem histogenesis','P','The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8141,10088,'phloem development','P','The formation of the principal food-conducting tissue of a vascular plant.','2013-10-27','NSRP'),(8142,10089,'xylem development','P','The formation of the principal water-conducting tissue of a vascular plant.','2013-10-27','NSRP'),(8143,10090,'trichome morphogenesis','P','The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8144,10091,'trichome branching','P','Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8145,10092,'specification of organ identity','P','The regionalization process in which the identity of an organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8146,10093,'specification of floral organ identity','P','The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8147,10094,'specification of carpel identity','P','The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8148,10095,'specification of petal identity','P','The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8149,10096,'specification of sepal identity','P','The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8150,10097,'specification of stamen identity','P','The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8151,10098,'suspensor development','P','The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.','2013-10-27','NSRP'),(8152,10099,'regulation of photomorphogenesis','P','Any process that modulates the rate or extent of photomorphogenesis.','2013-10-27','NSRP'),(8153,10100,'negative regulation of photomorphogenesis','P','Any process that stops, reduces or prevents photomorphogenesis.','2013-10-27','NSRP'),(8154,10101,'post-embryonic root morphogenesis','P','The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.','2013-10-27','NSRP'),(8155,10102,'lateral root morphogenesis','P','The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.','2013-10-27','NSRP'),(8156,10103,'stomatal complex morphogenesis','P','The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.','2013-10-27','NSRP'),(8157,10104,'regulation of ethylene mediated signaling pathway','P','Any process that modulates the frequency, rate or extent of ethylene (ethene) mediated signaling.','2013-10-27','NSRP'),(8158,10105,'negative regulation of ethylene mediated signaling pathway','P','Any process that stops or prevents ethylene (ethene) mediated signaling.','2013-10-27','NSRP'),(8159,10106,'cellular response to iron ion starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.','2013-10-27','NSRP'),(8160,10107,'potassium ion import','P','The directed movement of potassium ions into a cell or organelle.','2013-10-27','NSRP'),(8161,10108,'detection of glutamine','P','The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(8162,10109,'regulation of photosynthesis','P','Any process that modulates the frequency, rate or extent of photosynthesis.','2013-10-27','NSRP'),(8163,10110,'regulation of photosynthesis, dark reaction','P','Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.','2013-10-27','NSRP'),(8164,10111,'glyoxysome organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.','2013-10-27','NSRP'),(8165,10112,'regulation of systemic acquired resistance','P','Any process that modulates the frequency, rate or extent of systemic acquired resistance.','2013-10-27','NSRP'),(8166,10113,'negative regulation of systemic acquired resistance','P','Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.','2013-10-27','NSRP'),(8167,10114,'response to red light','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.','2013-10-27','NSRP'),(8168,10115,'regulation of abscisic acid biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.','2013-10-27','NSRP'),(8169,10116,'positive regulation of abscisic acid biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.','2013-10-27','NSRP'),(8170,10117,'photoprotection','P','Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.','2013-10-27','NSRP'),(8171,10118,'stomatal movement','P','The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).','2013-10-27','NSRP'),(8172,10119,'regulation of stomatal movement','P','Any process that modulates the frequency, rate or extent of stomatal movement.','2013-10-27','NSRP'),(8173,10120,'camalexin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.','2013-10-27','NSRP'),(8174,10121,'arginine catabolic process to proline via ornithine','P','The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.','2013-10-27','NSRP'),(8175,10122,'arginine catabolic process to alanine via ornithine','P','The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.','2013-10-27','NSRP'),(8176,10123,'acetate catabolic process to butyrate, ethanol, acetone and butanol','P','The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol.','2013-10-27','NSRP'),(8177,10124,'phenylacetate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of phenylacetate.','2013-10-27','NSRP'),(8178,10125,'mycothiol biosynthetic process','P','The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.','2013-10-27','NSRP'),(8179,10126,'mycothiol metabolic process','P','The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.','2013-10-27','NSRP'),(8180,10127,'mycothiol-dependent detoxification','P','The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.','2013-10-27','NSRP'),(8181,10128,'benzoate catabolic process via CoA ligation','P','The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.','2013-10-27','NSRP'),(8182,10129,'anaerobic cyclohexane-1-carboxylate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.','2013-10-27','NSRP'),(8183,10130,'anaerobic ethylbenzene catabolic process','P','The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.','2013-10-27','NSRP'),(8184,10131,'sucrose catabolic process, using invertase or sucrose synthase','P','OBSOLETE. The chemical reactions and pathways resulting in the breakdown of sucrose by the enzymatic action of either invertase or sucrose synthase.','2013-10-27','NSRP'),(8185,10132,'dhurrin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.','2013-10-27','NSRP'),(8186,10133,'proline catabolic process to glutamate','P','The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate.','2013-10-27','NSRP'),(8187,10134,'sulfate assimilation via adenylyl sulfate reduction','P','The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.','2013-10-27','NSRP'),(8188,10135,'ureide metabolic process','P','The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.','2013-10-27','NSRP'),(8189,10136,'ureide catabolic process','P','The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.','2013-10-27','NSRP'),(8190,10137,'ureide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.','2013-10-27','NSRP'),(8191,10138,'pyrimidine ribonucleotide salvage','P','The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.','2013-10-27','NSRP'),(8192,10139,'pyrimidine deoxyribonucleotide salvage','P','The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.','2013-10-27','NSRP'),(8193,10140,'adenine, hypoxanthine and their nucleoside salvage','P','OBSOLETE. The pathway by which adenine, hypoxanthine and their nucleosides from purine nucleotides breakdown are converted back to purine nucleotides. The salvage pathway is important where there is no de-novo purine nucleotide biosynthesis.','2013-10-27','NSRP'),(8194,10141,'guanine, xanthine and their nucleoside salvage','P','OBSOLETE. The pathway by which guanine, xanthine and their nucleoside from purine nucleotides breakdown are converted back to purine nucleotides. The pathway is important in cells where there is no de-novo purine nucleotides biosynthesis.','2013-10-27','NSRP'),(8195,10142,'farnesyl diphosphate biosynthetic process, mevalonate pathway','P','The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.','2013-10-27','NSRP'),(8196,10143,'cutin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.','2013-10-27','NSRP'),(8197,10144,'pyridoxal phosphate biosynthetic process from pyridoxamine','P','The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.','2013-10-27','NSRP'),(8198,10145,'fructan metabolic process','P','The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.','2013-10-27','NSRP'),(8199,10146,'fructan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.','2013-10-27','NSRP'),(8200,10147,'fructan catabolic process','P','The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.','2013-10-27','NSRP'),(8201,10148,'transpiration','P','Release of water by the plant into the air as water vapor mainly through leaves.','2013-10-27','NSRP'),(8202,10149,'senescence','P','OBSOLETE. A preprogrammed process associated with the dismantling of an anatomical structure and an overall decline in metabolism. This may include the breakdown of organelles, membranes and other cellular components. An example of this process is found in Arabidopsis thaliana, when older leaves or floral organs are shed.','2013-10-27','NSRP'),(8203,10150,'leaf senescence','P','The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.','2013-10-27','NSRP'),(8204,10151,'chloroplast elongation','P','Expansion of the chloroplast that usually precedes division.','2013-10-27','NSRP'),(8205,10152,'pollen maturation','P','The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.','2013-10-27','NSRP'),(8206,10153,'polar cell elongation','P','OBSOLETE. Cell expansion that results in an increase in cell size along the axis of an organ in a polarized fashion.','2013-10-27','NSRP'),(8207,10154,'fruit development','P','The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.','2013-10-27','NSRP'),(8208,10155,'regulation of proton transport','P','Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8209,10156,'sporocyte morphogenesis','P','OBSOLETE. Formation and development of sporocyte, the haploid spores of angiosperms which are initiated by the differentiation of a subset of floral cells into sporocytes, which then undergo meiotic divisions to form microspores and megaspores.','2013-10-27','NSRP'),(8210,10157,'response to chlorate','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.','2013-10-27','NSRP'),(8211,10158,'abaxial cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(8212,10159,'specification of organ position','P','The regionalization process in which information that determines the correct position at which organ primordia are formed is generated and perceived resulting in correct positioning of the new organ.','2013-10-27','NSRP'),(8213,10160,'formation of organ boundary','P','The regionalization process that specifies organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.','2013-10-27','NSRP'),(8214,10161,'red light signaling pathway','P','The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.','2013-10-27','NSRP'),(8215,10162,'seed dormancy process','P','A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.','2013-10-27','NSRP'),(8216,10163,'high-affinity potassium ion import','P','The directed, energized, high affinity movement of potassium ions into a cell or organelle, driven by cation symport with hydrogen or sodium ions.','2013-10-27','NSRP'),(8217,10164,'response to cesium ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.','2013-10-27','NSRP'),(8218,10165,'response to X-ray','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).','2013-10-27','NSRP'),(8219,10166,'wax metabolic process','P','The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.','2013-10-27','NSRP'),(8220,10167,'response to nitrate','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.','2013-10-27','NSRP'),(8221,10168,'ER body','C','A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.','2013-10-27','NSRP'),(8222,10169,'thioglucosidase complex','C','A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.','2013-10-27','NSRP'),(8223,10170,'glucose-1-phosphate adenylyltransferase complex','C','Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.','2013-10-27','NSRP'),(8224,10171,'body morphogenesis','P','The process in which the anatomical structures of the soma are generated and organized.','2013-10-27','NSRP'),(8225,10172,'embryonic body morphogenesis','P','The process in which the anatomical structures of the embryonic soma are generated and organized.','2013-10-27','NSRP'),(8226,10174,'nucleoside transmembrane transporter activity, against a concentration gradient','F','Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.','2013-10-27','NSRP'),(8227,10175,'sphingosine transmembrane transporter activity','F','Catalysis of the transfer of amino alcohol sphingosine from one side of the membrane to the other.','2013-10-27','NSRP'),(8228,10176,'homogentisate phytyltransferase activity','F','Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.','2013-10-27','NSRP'),(8229,10177,'2-(2\'-methylthio)ethylmalate synthase activity','F','Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2\'-methylthio)ethylmalic-acid + coenzyme A + H+.','2013-10-27','NSRP'),(8230,10178,'IAA-amino acid conjugate hydrolase activity','F','Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.','2013-10-27','NSRP'),(8231,10179,'IAA-Ala conjugate hydrolase activity','F','Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.','2013-10-27','NSRP'),(8232,10180,'thioglucosidase binding','F','Interacting selectively and non-covalently with the enzyme thioglucosidase.','2013-10-27','NSRP'),(8233,10181,'FMN binding','F','Interacting selectively and non-covalently with FMN, flavin mononucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.','2013-10-27','NSRP'),(8234,10182,'sugar mediated signaling pathway','P','The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.','2013-10-27','NSRP'),(8235,10183,'pollen tube guidance','P','The process in which the growth of pollen tube is directed towards the female gametophyte.','2013-10-27','NSRP'),(8236,10184,'cytokinin transport','P','The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8237,10185,'regulation of cellular defense response','P','Any process that modulates the frequency, rate or extent of cellular defense response.','2013-10-27','NSRP'),(8238,10186,'positive regulation of cellular defense response','P','Any process that activates or increases the frequency, rate or extent of cellular defense response.','2013-10-27','NSRP'),(8239,10187,'negative regulation of seed germination','P','Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.','2013-10-27','NSRP'),(8240,10188,'response to microbial phytotoxin','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.','2013-10-27','NSRP'),(8241,10189,'vitamin E biosynthetic process','P','The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.','2013-10-27','NSRP'),(8242,10190,'cytochrome b6f complex assembly','P','Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.','2013-10-27','NSRP'),(8243,10191,'mucilage metabolic process','P','The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.','2013-10-27','NSRP'),(8244,10192,'mucilage biosynthetic process','P','The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.','2013-10-27','NSRP'),(8245,10193,'response to ozone','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.','2013-10-27','NSRP'),(8246,10194,'microRNA metabolic process','P','OBSOLETE. The chemical reactions and pathways involving microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.','2013-10-27','NSRP'),(8247,10195,'microRNA biosynthetic process','P','OBSOLETE. The chemical reactions and pathways resulting in the formation of microRNA, a large family of 21-22 nucleotide non-coding RNAs with presumed post-transcriptional regulatory activity.','2013-10-27','NSRP'),(8248,10196,'nonphotochemical quenching','P','The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.','2013-10-27','NSRP'),(8249,10197,'polar nucleus fusion','P','The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.','2013-10-27','NSRP'),(8250,10198,'synergid death','P','Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.','2013-10-27','NSRP'),(8251,10199,'organ boundary specification between lateral organs and the meristem','P','The process in which boundaries between lateral organs and the meristem is established and maintained.','2013-10-27','NSRP'),(8252,10200,'response to chitin','P','A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.','2013-10-27','NSRP'),(8253,10201,'response to continuous far red light stimulus by the high-irradiance response system','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.','2013-10-27','NSRP'),(8254,10202,'response to low fluence red light stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.','2013-10-27','NSRP'),(8255,10203,'response to very low fluence red light stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.','2013-10-27','NSRP'),(8256,10204,'defense response signaling pathway, resistance gene-independent','P','A series of molecular signals that is activated during defense response and does not depend upon R-genes.','2013-10-27','NSRP'),(8257,10205,'photoinhibition','P','The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.','2013-10-27','NSRP'),(8258,10206,'photosystem II repair','P','Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.','2013-10-27','NSRP'),(8259,10207,'photosystem II assembly','P','The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.','2013-10-27','NSRP'),(8260,10208,'pollen wall assembly','P','The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.','2013-10-27','NSRP'),(8261,10209,'vacuolar sorting signal binding','F','Interacting selectively and non-covalently with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.','2013-10-27','NSRP'),(8262,10210,'IAA-Phe conjugate hydrolase activity','F','Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.','2013-10-27','NSRP'),(8263,10211,'IAA-Leu conjugate hydrolase activity','F','Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.','2013-10-27','NSRP'),(8264,10212,'response to ionizing radiation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.','2013-10-27','NSRP'),(8265,10213,'non-photoreactive DNA repair','P','A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.','2013-10-27','NSRP'),(8266,10214,'seed coat development','P','The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.','2013-10-27','NSRP'),(8267,10215,'cellulose microfibril organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.','2013-10-27','NSRP'),(8268,10216,'maintenance of DNA methylation','P','Any process involved in maintaining the methylation state of a nucleotide sequence.','2013-10-27','NSRP'),(8269,10217,'cellular aluminum ion homeostasis','P','Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell.','2013-10-27','NSRP'),(8270,10218,'response to far red light','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.','2013-10-27','NSRP'),(8271,10219,'regulation of vernalization response','P','Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.','2013-10-27','NSRP'),(8272,10220,'positive regulation of vernalization response','P','Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.','2013-10-27','NSRP'),(8273,10221,'negative regulation of vernalization response','P','Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.','2013-10-27','NSRP'),(8274,10222,'stem vascular tissue pattern formation','P','Vascular tissue pattern formation as it occurs in the stem of vascular plants.','2013-10-27','NSRP'),(8275,10223,'secondary shoot formation','P','The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.','2013-10-27','NSRP'),(8276,10224,'response to UV-B','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 290 to 320 nm.','2013-10-27','NSRP'),(8277,10225,'response to UV-C','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 290 nm.','2013-10-27','NSRP'),(8278,10226,'response to lithium ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.','2013-10-27','NSRP'),(8279,10227,'floral organ abscission','P','The controlled shedding of floral organs.','2013-10-27','NSRP'),(8280,10228,'vegetative to reproductive phase transition of meristem','P','The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.','2013-10-27','NSRP'),(8281,10229,'inflorescence development','P','The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.','2013-10-27','NSRP'),(8282,10230,'alternative respiration','P','Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.','2013-10-27','NSRP'),(8283,10231,'maintenance of seed dormancy','P','Any process that maintains a seed in a dormant state.','2013-10-27','NSRP'),(8284,10232,'vascular transport','P','The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.','2013-10-27','NSRP'),(8285,10233,'phloem transport','P','The directed movement of substances, into, out of or within a cell, either in a phloem tissue or in the phloem membrane.','2013-10-27','NSRP'),(8286,10234,'anther wall tapetum cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(8287,10235,'guard mother cell cytokinesis','P','The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.','2013-10-27','NSRP'),(8288,10236,'plastoquinone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.','2013-10-27','NSRP'),(8289,10238,'response to proline','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.','2013-10-27','NSRP'),(8290,10239,'chloroplast mRNA processing','P','Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.','2013-10-27','NSRP'),(8291,10240,'plastid pyruvate dehydrogenase complex','C','Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.','2013-10-27','NSRP'),(8292,10241,'ent-kaurene oxidation to kaurenoic acid','P','The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.','2013-10-27','NSRP'),(8293,10242,'oxygen evolving activity','F','Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.','2013-10-27','NSRP'),(8294,10243,'response to organonitrogen compound','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.','2013-10-27','NSRP'),(8295,10244,'response to low fluence blue light stimulus by blue low-fluence system','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.','2013-10-27','NSRP'),(8296,10245,'radial microtubular system formation','P','Formation of radial microtubular systems during male meiotic cytokinesis in plants.','2013-10-27','NSRP'),(8297,10246,'rhamnogalacturonan I biosynthetic process','P','The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.','2013-10-27','NSRP'),(8298,10247,'detection of phosphate ion','P','The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(8299,10248,'establishment or maintenance of transmembrane electrochemical gradient','P','The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8300,10249,'auxin conjugate metabolic process','P','The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.','2013-10-27','NSRP'),(8301,10250,'S-methylmethionine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.','2013-10-27','NSRP'),(8302,10252,'auxin homeostasis','P','A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.','2013-10-27','NSRP'),(8303,10253,'UDP-rhamnose biosynthetic process','P','The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(8304,10254,'nectary development','P','The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.','2013-10-27','NSRP'),(8305,10255,'glucose mediated signaling pathway','P','The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.','2013-10-27','NSRP'),(8306,10256,'endomembrane system organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.','2013-10-27','NSRP'),(8307,10257,'NADH dehydrogenase complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.','2013-10-27','NSRP'),(8308,10258,'NADH dehydrogenase complex (plastoquinone) assembly','P','The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.','2013-10-27','NSRP'),(8309,10259,'multicellular organismal aging','P','An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).','2013-10-27','NSRP'),(8310,10260,'organ senescence','P','The process that occurs in an organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism. An example of this process is found in Arabidopsis thaliana.','2013-10-27','NSRP'),(8311,10262,'somatic embryogenesis','P','Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.','2013-10-27','NSRP'),(8312,10263,'tricyclic triterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.','2013-10-27','NSRP'),(8313,10264,'myo-inositol hexakisphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.','2013-10-27','NSRP'),(8314,10265,'SCF complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.','2013-10-27','NSRP'),(8315,10266,'response to vitamin B1','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.','2013-10-27','NSRP'),(8316,10267,'production of ta-siRNAs involved in RNA interference','P','Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs.','2013-10-27','NSRP'),(8317,10268,'brassinosteroid homeostasis','P','Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.','2013-10-27','NSRP'),(8318,10269,'response to selenium ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.','2013-10-27','NSRP'),(8319,10270,'photosystem II oxygen evolving complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.','2013-10-27','NSRP'),(8320,10271,'regulation of chlorophyll catabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.','2013-10-27','NSRP'),(8321,10272,'response to silver ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.','2013-10-27','NSRP'),(8322,10273,'detoxification of copper ion','P','Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.','2013-10-27','NSRP'),(8323,10274,'hydrotropism','P','Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.','2013-10-27','NSRP'),(8324,10275,'NAD(P)H dehydrogenase complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.','2013-10-27','NSRP'),(8325,10276,'phytol kinase activity','F','Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.','2013-10-27','NSRP'),(8326,10277,'chlorophyllide a oxygenase [overall] activity','F','Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.','2013-10-27','NSRP'),(8327,10278,'chloroplast outer membrane translocon','C','The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.','2013-10-27','NSRP'),(8328,10279,'indole-3-acetic acid amido synthetase activity','F','Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.','2013-10-27','NSRP'),(8329,10280,'UDP-L-rhamnose synthase activity','F','Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.','2013-10-27','NSRP'),(8330,10282,'senescence-associated vacuole','C','A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.','2013-10-27','NSRP'),(8331,10283,'pinoresinol reductase activity','F','Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.','2013-10-27','NSRP'),(8332,10284,'lariciresinol reductase activity','F','Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.','2013-10-27','NSRP'),(8333,10285,'L,L-diaminopimelate aminotransferase activity','F','Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+).','2013-10-27','NSRP'),(8334,10286,'heat acclimation','P','Any process that increases heat tolerance of an organism in response to high temperatures.','2013-10-27','NSRP'),(8335,10287,'plastoglobule','C','A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.','2013-10-27','NSRP'),(8336,10288,'response to lead ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.','2013-10-27','NSRP'),(8337,10289,'homogalacturonan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.','2013-10-27','NSRP'),(8338,10290,'chlorophyll catabolite transmembrane transporter activity','F','Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of the membrane to the other.','2013-10-27','NSRP'),(8339,10291,'carotene beta-ring hydroxylase activity','F','Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.','2013-10-27','NSRP'),(8340,10292,'GTP:GDP antiporter activity','F','Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).','2013-10-27','NSRP'),(8341,10293,'abscisic aldehyde oxidase activity','F','Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+).','2013-10-27','NSRP'),(8342,10294,'abscisic acid glucosyltransferase activity','F','Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.','2013-10-27','NSRP'),(8343,10295,'(+)-abscisic acid 8\'-hydroxylase activity','F','Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8\'-hydroxyabscisate + H(2)O + NADP(+).','2013-10-27','NSRP'),(8344,10296,'prenylcysteine methylesterase activity','F','Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.','2013-10-27','NSRP'),(8345,10297,'heteropolysaccharide binding','F','Interacting selectively and non-covalently with heteropolysaccharides. A heteropolysaccharide is a glycan composed of more than one type of monosaccharide residue.','2013-10-27','NSRP'),(8346,10298,'dihydrocamalexic acid decarboxylase activity','F','Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.','2013-10-27','NSRP'),(8347,10299,'detoxification of cobalt ion','P','Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.','2013-10-27','NSRP'),(8348,10301,'xanthoxin dehydrogenase activity','F','Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH.','2013-10-27','NSRP'),(8349,10302,'2-oxoglutarate-dependent dioxygenase activity','F','Hydroxylase, with 2-oxoglutarate as one donor, and incorporation or reduction of one atom each of oxygen into both donors.','2012-03-14','NSRP'),(8350,10303,'limit dextrinase activity','F','Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.','2013-10-27','NSRP'),(8351,10304,'PSII associated light-harvesting complex II catabolic process','P','The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.','2013-10-27','NSRP'),(8352,10305,'leaf vascular tissue pattern formation','P','Vascular tissue pattern formation as it occurs in the leaf of vascular plants.','2013-10-27','NSRP'),(8353,10306,'rhamnogalacturonan II biosynthetic process','P','The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.','2013-10-27','NSRP'),(8354,10307,'acetylglutamate kinase regulator activity','F','Modulates the enzyme activity of acetylglutamate kinase.','2013-10-27','NSRP'),(8355,10308,'acireductone dioxygenase (Ni2+-requiring) activity','F','Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate.','2013-10-27','NSRP'),(8356,10309,'acireductone dioxygenase [iron(II)-requiring] activity','F','Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+).','2013-10-27','NSRP'),(8357,10310,'regulation of hydrogen peroxide metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.','2013-10-27','NSRP'),(8358,10311,'lateral root formation','P','The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.','2013-10-27','NSRP'),(8359,10312,'detoxification of zinc ion','P','Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.','2013-10-27','NSRP'),(8360,10313,'phytochrome binding','F','Interacting selectively and non-covalently with phytochrome.','2013-10-27','NSRP'),(8361,10314,'phosphatidylinositol-5-phosphate binding','F','Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5\' position.','2013-10-27','NSRP'),(8362,10315,'auxin efflux','P','The process involved in the transport of auxin out of the cell.','2013-10-27','NSRP'),(8363,10316,'pyrophosphate-dependent phosphofructokinase complex','C','Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.','2013-10-27','NSRP'),(8364,10317,'pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex','C','Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.','2013-10-27','NSRP'),(8365,10318,'pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex','C','Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.','2013-10-27','NSRP'),(8366,10319,'stromule','C','Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.','2013-10-27','NSRP'),(8367,10320,'arginine/lysine endopeptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of peptide linkages in oligopeptides or polypeptides by a reaction mechanism in which arginine or lysine residues act as nucleophiles.','2013-10-27','NSRP'),(8368,10321,'regulation of vegetative phase change','P','Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.','2013-10-27','NSRP'),(8369,10322,'regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).','2013-10-27','NSRP'),(8370,10323,'negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).','2013-10-27','NSRP'),(8371,10324,'membrane invagination','P','The infolding of a membrane, resulting in formation of a vesicle.','2013-10-27','NSRP'),(8372,10325,'raffinose family oligosaccharide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).','2013-10-27','NSRP'),(8373,10326,'methionine-oxo-acid transaminase activity','F','Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid.','2013-10-27','NSRP'),(8374,10327,'acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.','2013-10-27','NSRP'),(8375,10328,'auxin influx transmembrane transporter activity','F','Catalysis of the transfer of auxin, from one side of a membrane to the other, into a cell.','2013-10-27','NSRP'),(8376,10329,'auxin efflux transmembrane transporter activity','F','Catalysis of the transfer of auxin, from one side of a membrane to the other, out of a cell.','2013-10-27','NSRP'),(8377,10330,'cellulose synthase complex','C','A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.','2013-10-27','NSRP'),(8378,10331,'gibberellin binding','F','Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(8379,10332,'response to gamma radiation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.','2013-10-27','NSRP'),(8380,10333,'terpene synthase activity','F','Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.','2013-10-27','NSRP'),(8381,10334,'sesquiterpene synthase activity','F','Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.','2013-10-27','NSRP'),(8382,10335,'response to non-ionic osmotic stress','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.','2013-10-27','NSRP'),(8383,10336,'gibberellic acid homeostasis','P','Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.','2013-10-27','NSRP'),(8384,10337,'regulation of salicylic acid metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.','2013-10-27','NSRP'),(8385,10338,'leaf formation','P','The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(8386,10339,'external side of cell wall','C','The side of the cell wall that is opposite to the side that faces the cell and its contents.','2013-10-27','NSRP'),(8387,10340,'carboxyl-O-methyltransferase activity','F','Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.','2013-10-27','NSRP'),(8388,10341,'gibberellin carboxyl-O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.','2013-10-27','NSRP'),(8389,10342,'endosperm cellularization','P','The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.','2013-10-27','NSRP'),(8390,10343,'singlet oxygen-mediated programmed cell death','P','Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.','2013-10-27','NSRP'),(8391,10344,'seed oilbody biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.','2013-10-27','NSRP'),(8392,10345,'suberin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.','2013-10-27','NSRP'),(8393,10346,'shoot axis formation','P','The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(8394,10347,'L-galactose-1-phosphate phosphatase activity','F','Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.','2013-10-27','NSRP'),(8395,10348,'lithium:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).','2013-10-27','NSRP'),(8396,10349,'L-galactose dehydrogenase activity','F','Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.','2013-10-27','NSRP'),(8397,10350,'cellular response to magnesium starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.','2013-10-27','NSRP'),(8398,10351,'lithium ion transport','P','The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8399,10352,'lithium ion export','P','The directed movement of lithium ion out of a cell or organelle.','2013-10-27','NSRP'),(8400,10353,'response to trehalose stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.','2013-10-27','NSRP'),(8401,10354,'homogentisate prenyltransferase activity','F','Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.','2013-10-27','NSRP'),(8402,10355,'homogentisate farnesyltransferase activity','F','Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.','2013-10-27','NSRP'),(8403,10356,'homogentisate geranylgeranyltransferase activity','F','Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.','2013-10-27','NSRP'),(8404,10357,'homogentisate solanesyltransferase activity','F','Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.','2013-10-27','NSRP'),(8405,10358,'leaf shaping','P','The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.','2013-10-27','NSRP'),(8406,10359,'regulation of anion channel activity','P','Any process that modulates the frequency, rate or extent of anion channel activity.','2013-10-27','NSRP'),(8407,10360,'negative regulation of anion channel activity','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.','2013-10-27','NSRP'),(8408,10361,'regulation of anion channel activity by blue light','P','Any process in which blue light modulates the frequency, rate or extent of anion channel activity.','2013-10-27','NSRP'),(8409,10362,'negative regulation of anion channel activity by blue light','P','Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.','2013-10-27','NSRP'),(8410,10363,'regulation of plant-type hypersensitive response','P','Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.','2013-10-27','NSRP'),(8411,10364,'regulation of ethylene biosynthetic process','P','Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.','2013-10-27','NSRP'),(8412,10365,'positive regulation of ethylene biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.','2013-10-27','NSRP'),(8413,10366,'negative regulation of ethylene biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.','2013-10-27','NSRP'),(8414,10367,'extracellular isoamylase complex','C','A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.','2013-10-27','NSRP'),(8415,10368,'chloroplast isoamylase complex','C','A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.','2013-10-27','NSRP'),(8416,10369,'chromocenter','C','A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure.','2013-10-27','NSRP'),(8417,10370,'perinucleolar chromocenter','C','A chromocenter adjacent to the nucleolus.','2013-10-27','NSRP'),(8418,10371,'regulation of gibberellin biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.','2013-10-27','NSRP'),(8419,10372,'positive regulation of gibberellin biosynthetic process','P','Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.','2013-10-27','NSRP'),(8420,10373,'negative regulation of gibberellin biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.','2013-10-27','NSRP'),(8421,10374,'stomatal complex development','P','The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.','2013-10-27','NSRP'),(8422,10375,'stomatal complex patterning','P','The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.','2013-10-27','NSRP'),(8423,10376,'stomatal complex formation','P','The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.','2013-10-27','NSRP'),(8424,10377,'guard cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.','2013-10-27','NSRP'),(8425,10378,'temperature compensation of the circadian clock','P','The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.','2013-10-27','NSRP'),(8426,10379,'phaseic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).','2013-10-27','NSRP'),(8427,10380,'regulation of chlorophyll biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.','2013-10-27','NSRP'),(8428,10381,'attachment of peroxisome to chloroplast','P','The process in which a peroxisome is transported to, and/or maintained in, a location adjacent to the chloroplast.','2013-10-27','NSRP'),(8429,10382,'cellular cell wall macromolecule metabolic process','P','The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis, occurring at the level of the cell.','2012-03-14','NSRP'),(8430,10383,'cell wall polysaccharide metabolic process','P','The chemical reactions and pathways involving cell wall polysaccharides.','2013-10-27','NSRP'),(8431,10384,'cell wall proteoglycan metabolic process','P','The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.','2013-10-27','NSRP'),(8432,10385,'double-stranded methylated DNA binding','F','Interacting selectively and non-covalently with double-stranded methylated DNA. Cytosine methylation in DNA is an important mechanism for establishing stable heritable epigenetic marks.','2013-10-27','NSRP'),(8433,10386,'lateral root primordium development','P','The process whose specific outcome is the progression of the lateral root primordium over time, which initiates the formation to the mature structure. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.','2012-03-14','NSRP'),(8434,10387,'COP9 signalosome assembly','P','The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.','2013-10-27','NSRP'),(8435,10388,'cullin deneddylation','P','The modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1).','2013-10-27','NSRP'),(8436,10389,'regulation of G2/M transition of mitotic cell cycle','P','Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.','2013-10-27','NSRP'),(8437,10390,'histone monoubiquitination','P','The modification of histones by addition of a single ubiquitin group.','2013-10-27','NSRP'),(8438,10391,'glucomannan metabolic process','P','The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.','2013-10-27','NSRP'),(8439,10392,'galactoglucomannan metabolic process','P','The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.','2013-10-27','NSRP'),(8440,10393,'galacturonan metabolic process','P','The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.','2013-10-27','NSRP'),(8441,10394,'homogalacturonan metabolic process','P','The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.','2013-10-27','NSRP'),(8442,10395,'rhamnogalacturonan I metabolic process','P','The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.','2013-10-27','NSRP'),(8443,10396,'rhamnogalacturonan II metabolic process','P','The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.','2013-10-27','NSRP'),(8444,10397,'apiogalacturonan metabolic process','P','The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.','2013-10-27','NSRP'),(8445,10398,'xylogalacturonan metabolic process','P','The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.','2013-10-27','NSRP'),(8446,10399,'rhamnogalacturonan I backbone metabolic process','P','The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.','2013-10-27','NSRP'),(8447,10400,'rhamnogalacturonan I side chain metabolic process','P','The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.','2013-10-27','NSRP'),(8448,10401,'pectic galactan metabolic process','P','The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.','2013-10-27','NSRP'),(8449,10402,'pectic arabinan metabolic process','P','The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.','2013-10-27','NSRP'),(8450,10403,'pectic arabinogalactan I metabolic process','P','The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.','2013-10-27','NSRP'),(8451,10404,'cell wall hydroxyproline-rich glycoprotein metabolic process','P','The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.','2013-10-27','NSRP'),(8452,10405,'arabinogalactan protein metabolic process','P','The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.','2013-10-27','NSRP'),(8453,10406,'classical arabinogalactan protein metabolic process','P','The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.','2013-10-27','NSRP'),(8454,10407,'non-classical arabinogalactan protein metabolic process','P','The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.','2013-10-27','NSRP'),(8455,10408,'fasciclin-like arabinogalactan protein metabolic process','P','The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.','2013-10-27','NSRP'),(8456,10409,'extensin metabolic process','P','The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.','2013-10-27','NSRP'),(8457,10410,'hemicellulose metabolic process','P','The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.','2013-10-27','NSRP'),(8458,10411,'xyloglucan metabolic process','P','The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.','2013-10-27','NSRP'),(8459,10412,'mannan metabolic process','P','The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.','2013-10-27','NSRP'),(8460,10413,'glucuronoxylan metabolic process','P','The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.','2013-10-27','NSRP'),(8461,10414,'glucuronoarabinoxylan metabolic process','P','The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.','2013-10-27','NSRP'),(8462,10415,'unsubstituted mannan metabolic process','P','The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units.','2013-10-27','NSRP'),(8463,10416,'arabinoxylan-containing compound metabolic process','P','The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units.','2013-10-27','NSRP'),(8464,10417,'glucuronoxylan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.','2013-10-27','NSRP'),(8465,10418,'rhamnogalacturonan II backbone metabolic process','P','The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues.','2013-10-27','NSRP'),(8466,10419,'rhamnogalacturonan II side chain metabolic process','P','The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.','2013-10-27','NSRP'),(8467,10420,'polyprenyldihydroxybenzoate methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + 3-polyprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-polyprenyl-4-hydroxy-5-methoxybenzoate + H+.','2013-10-27','NSRP'),(8468,10421,'hydrogen peroxide-mediated programmed cell death','P','Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.','2013-10-27','NSRP'),(8469,10422,'regulation of brassinosteroid biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.','2013-10-27','NSRP'),(8470,10423,'negative regulation of brassinosteroid biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.','2013-10-27','NSRP'),(8471,10424,'DNA methylation on cytosine within a CG sequence','P','The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.','2013-10-27','NSRP'),(8472,10425,'DNA methylation on cytosine within a CNG sequence','P','The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide.','2013-10-27','NSRP'),(8473,10426,'DNA methylation on cytosine within a CHH sequence','P','The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.','2013-10-27','NSRP'),(8474,10427,'abscisic acid binding','F','Interacting selectively and non-covalently with abscisic acid, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(8475,10428,'methyl-CpNpG binding','F','Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.','2013-10-27','NSRP'),(8476,10429,'methyl-CpNpN binding','F','Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.','2013-10-27','NSRP'),(8477,10430,'fatty acid omega-oxidation','P','A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.','2013-10-27','NSRP'),(8478,10431,'seed maturation','P','A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.','2013-10-27','NSRP'),(8479,10432,'bract development','P','The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.','2013-10-27','NSRP'),(8480,10433,'bract morphogenesis','P','The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.','2013-10-27','NSRP'),(8481,10434,'bract formation','P','The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.','2013-10-27','NSRP'),(8482,10435,'3-oxo-2-(2\'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity','F','Catalysis of the reaction: ATP + 3-oxo-2-(2\'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2\'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2\'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0.','2013-10-27','NSRP'),(8483,10436,'carotenoid dioxygenase activity','F','Catalysis of the oxidative cleavage of carotenoids.','2013-10-27','NSRP'),(8484,10437,'9,10 (9\', 10\')-carotenoid-cleaving dioxygenase activity','F','Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9\', 10\') double bond.','2013-10-27','NSRP'),(8485,10438,'cellular response to sulfur starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.','2013-10-27','NSRP'),(8486,10439,'regulation of glucosinolate biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.','2013-10-27','NSRP'),(8487,10440,'stomatal lineage progression','P','The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.','2013-10-27','NSRP'),(8488,10441,'guard cell development','P','The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.','2013-10-27','NSRP'),(8489,10442,'guard cell morphogenesis','P','Generation and organization of the polarized cell that is capable of turgor driven movement.','2013-10-27','NSRP'),(8490,10443,'meristemoid mother cell division','P','The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.','2013-10-27','NSRP'),(8491,10444,'guard mother cell differentiation','P','The process in which a meristemoid acquires the specialized features of a guard mother cell.','2013-10-27','NSRP'),(8492,10445,'nuclear dicing body','C','A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.','2013-10-27','NSRP'),(8493,10446,'response to alkalinity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7.','2013-10-27','NSRP'),(8494,10447,'response to acidity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7.','2013-10-27','NSRP'),(8495,10448,'vegetative meristem growth','P','The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.','2013-10-27','NSRP'),(8496,10449,'root meristem growth','P','The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.','2013-10-27','NSRP'),(8497,10450,'inflorescence meristem growth','P','The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.','2013-10-27','NSRP'),(8498,10451,'floral meristem growth','P','The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.','2013-10-27','NSRP'),(8499,10452,'histone H3-K36 methylation','P','The modification of histone H3 by addition of a methyl group to lysine at position 36 of the histone.','2013-10-27','NSRP'),(8500,10453,'regulation of cell fate commitment','P','Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.','2013-10-27','NSRP'),(8501,10454,'negative regulation of cell fate commitment','P','Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.','2013-10-27','NSRP'),(8502,10455,'positive regulation of cell fate commitment','P','Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.','2013-10-27','NSRP'),(8503,10456,'cell proliferation in dorsal spinal cord','P','The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.','2013-10-27','NSRP'),(8504,10457,'centriole-centriole cohesion','P','The process in which the two centrioles within a centrosome remain tightly paired.','2013-10-27','NSRP'),(8505,10458,'exit from mitosis','P','The cell cycle process where a cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.','2013-10-27','NSRP'),(8506,10459,'negative regulation of heart rate','P','Any process that stops, prevents or reduces the frequency or rate of heart contraction.','2013-10-27','NSRP'),(8507,10460,'positive regulation of heart rate','P','Any process that activates or increases the frequency or rate of heart contraction.','2013-10-27','NSRP');
INSERT INTO `GO` VALUES (8508,10461,'light-activated ion channel activity','F','Catalysis of the transmembrane transfer of an ion by a channel that opens in response to a light stimulus.','2013-10-27','NSRP'),(8509,10462,'regulation of light-activated voltage-gated calcium channel activity','P','Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.','2013-10-27','NSRP'),(8510,10463,'mesenchymal cell proliferation','P','The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.','2013-10-27','NSRP'),(8511,10464,'regulation of mesenchymal cell proliferation','P','Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.','2013-10-27','NSRP'),(8512,10465,'nerve growth factor receptor activity','F','Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.','2013-10-27','NSRP'),(8513,10466,'negative regulation of peptidase activity','P','Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.','2013-10-27','NSRP'),(8514,10467,'gene expression','P','The process in which a gene\'s sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.','2013-10-27','NSRP'),(8515,10468,'regulation of gene expression','P','Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene\'s coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.','2013-10-27','NSRP'),(8516,10469,'regulation of receptor activity','P','Any process that modulates the frequency, rate or extent of receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.','2013-10-27','NSRP'),(8517,10470,'regulation of gastrulation','P','Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.','2013-10-27','NSRP'),(8518,10471,'GDP-galactose:mannose-1-phosphate guanylyltransferase activity','F','Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate.','2013-10-27','NSRP'),(8519,10472,'GDP-galactose:glucose-1-phosphate guanylyltransferase activity','F','Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose.','2013-10-27','NSRP'),(8520,10473,'GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity','F','Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.','2013-10-27','NSRP'),(8521,10474,'glucose-1-phosphate guanylyltransferase (GDP) activity','F','Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose.','2013-10-27','NSRP'),(8522,10475,'galactose-1-phosphate guanylyltransferase (GDP) activity','F','Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose.','2013-10-27','NSRP'),(8523,10476,'gibberellin mediated signaling pathway','P','The series of molecular signals generated as a consequence of gibberellin stimulus.','2013-10-27','NSRP'),(8524,10477,'response to sulfur dioxide','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.','2013-10-27','NSRP'),(8525,10478,'chlororespiration','P','A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.','2013-10-27','NSRP'),(8526,10479,'stele development','P','The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.','2013-10-27','NSRP'),(8527,10480,'microsporocyte differentiation','P','The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.','2013-10-27','NSRP'),(8528,10481,'epidermal cell division','P','Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.','2013-10-27','NSRP'),(8529,10482,'regulation of epidermal cell division','P','Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.','2013-10-27','NSRP'),(8530,10483,'pollen tube reception','P','Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.','2013-10-27','NSRP'),(8531,10484,'H3 histone acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.','2013-10-27','NSRP'),(8532,10485,'H4 histone acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.','2013-10-27','NSRP'),(8533,10486,'manganese:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).','2013-10-27','NSRP'),(8534,10487,'thermospermine synthase activity','F','Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5\'-thioadenosine + thermospermine + H+.','2013-10-27','NSRP'),(8535,10488,'UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity','F','Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.','2013-10-27','NSRP'),(8536,10489,'UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity','F','Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.','2013-10-27','NSRP'),(8537,10490,'UDP-4-keto-rhamnose-4-keto-reductase activity','F','Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.','2013-10-27','NSRP'),(8538,10491,'UTP:arabinose-1-phosphate uridylyltransferase activity','F','Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.','2013-10-27','NSRP'),(8539,10492,'maintenance of shoot apical meristem identity','P','The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.','2013-10-27','NSRP'),(8540,10493,'Lewis a epitope biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.','2013-10-27','NSRP'),(8541,10494,'cytoplasmic stress granule','C','A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.','2013-10-27','NSRP'),(8542,10495,'long-distance posttranscriptional gene silencing','P','A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place.','2013-10-27','NSRP'),(8543,10496,'intercellular transport','P','The movement of substances between cells in a multicellular organism.','2013-10-27','NSRP'),(8544,10497,'plasmodesmata-mediated intercellular transport','P','The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.','2013-10-27','NSRP'),(8545,10498,'proteasomal protein catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.','2013-10-27','NSRP'),(8546,10499,'proteasomal ubiquitin-independent protein catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.','2013-10-27','NSRP'),(8547,10500,'transmitting tissue development','P','The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.','2013-10-27','NSRP'),(8548,10501,'RNA secondary structure unwinding','P','The process in which a secondary structure of RNA are broken or \'melted\'.','2013-10-27','NSRP'),(8549,10503,'negative regulation of cell cycle arrest in response to nitrogen starvation','P','Any process that stops, prevents or reduces the frequency or rate of cell cycle arrest in response to nitrogen starvation.','2013-10-27','NSRP'),(8550,10504,'regulation of cell cycle arrest in response to nitrogen starvation','P','Any process that modulates the frequency, rate or extent of cell cycle arrest in response to nitrogen starvation.','2013-10-27','NSRP'),(8551,10505,'positive regulation of cell cycle arrest in response to nitrogen starvation','P','Any process that increases the frequency or rate of cell cycle arrest in response to nitrogen starvation.','2013-10-27','NSRP'),(8552,10506,'regulation of autophagy','P','Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.','2013-10-27','NSRP'),(8553,10507,'negative regulation of autophagy','P','Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.','2013-10-27','NSRP'),(8554,10508,'positive regulation of autophagy','P','Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.','2013-10-27','NSRP'),(8555,10509,'polyamine homeostasis','P','Any biological process involved in the maintenance of an internal steady state of a polyamine.','2013-10-27','NSRP'),(8556,10510,'regulation of acetyl-CoA biosynthetic process from pyruvate','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.','2013-10-27','NSRP'),(8557,10511,'regulation of phosphatidylinositol biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.','2013-10-27','NSRP'),(8558,10512,'negative regulation of phosphatidylinositol biosynthetic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.','2013-10-27','NSRP'),(8559,10513,'positive regulation of phosphatidylinositol biosynthetic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.','2013-10-27','NSRP'),(8560,10514,'induction of conjugation with cellular fusion','P','The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.','2013-10-27','NSRP'),(8561,10515,'negative regulation of induction of conjugation with cellular fusion','P','Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.','2013-10-27','NSRP'),(8562,10516,'negative regulation of cellular response to nitrogen starvation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.','2013-10-27','NSRP'),(8563,10517,'regulation of phospholipase activity','P','Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.','2013-10-27','NSRP'),(8564,10518,'positive regulation of phospholipase activity','P','Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.','2013-10-27','NSRP'),(8565,10519,'negative regulation of phospholipase activity','P','Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.','2013-10-27','NSRP'),(8566,10520,'regulation of reciprocal meiotic recombination','P','Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8567,10521,'telomerase inhibitor activity','F','Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3\'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.','2013-10-27','NSRP'),(8568,10522,'regulation of calcium ion transport into cytosol','P','Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.','2013-10-27','NSRP'),(8569,10523,'negative regulation of calcium ion transport into cytosol','P','Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.','2013-10-27','NSRP'),(8570,10524,'positive regulation of calcium ion transport into cytosol','P','Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.','2013-10-27','NSRP'),(8571,10525,'regulation of transposition, RNA-mediated','P','Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.','2013-10-27','NSRP'),(8572,10526,'negative regulation of transposition, RNA-mediated','P','Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.','2013-10-27','NSRP'),(8573,10527,'positive regulation of transposition, RNA-mediated','P','Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.','2013-10-27','NSRP'),(8574,10528,'regulation of transposition','P','Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.','2013-10-27','NSRP'),(8575,10529,'negative regulation of transposition','P','Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.','2013-10-27','NSRP'),(8576,10530,'positive regulation of transposition','P','Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.','2013-10-27','NSRP'),(8577,10531,'activation of JAK1 kinase activity','P','The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.','2013-10-27','NSRP'),(8578,10532,'regulation of activation of JAK1 kinase activity','P','Any process that modulates the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.','2013-10-27','NSRP'),(8579,10533,'regulation of activation of Janus kinase activity','P','Any process that modulates the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.','2013-10-27','NSRP'),(8580,10534,'regulation of activation of JAK2 kinase activity','P','Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.','2013-10-27','NSRP'),(8581,10535,'positive regulation of activation of JAK2 kinase activity','P','Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.','2013-10-27','NSRP'),(8582,10536,'positive regulation of activation of Janus kinase activity','P','Any process that increases the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.','2013-10-27','NSRP'),(8583,10537,'positive regulation of activation of JAK1 kinase activity','P','Any process that increases the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.','2013-10-27','NSRP'),(8584,10538,'Hsp27 protein regulator activity','F','OBSOLETE. Modulates the activity of the Hsp27 molecular chaperone.','2013-10-27','NSRP'),(8585,10539,'Hsp27 protein inhibitor activity','F','OBSOLETE. Stops, prevents or reduces the activity of the Hsp27 molecular chaperone.','2013-10-27','NSRP'),(8586,10540,'basipetal auxin transport','P','The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.','2013-10-27','NSRP'),(8587,10541,'acropetal auxin transport','P','The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.','2013-10-27','NSRP'),(8588,10542,'nitrate efflux transmembrane transporter activity','F','Catalysis of the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(8589,10543,'regulation of platelet activation','P','Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.','2013-10-27','NSRP'),(8590,10544,'negative regulation of platelet activation','P','Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.','2013-10-27','NSRP'),(8591,10545,'Hsp90 protein regulator activity','F','OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsp90.','2013-10-27','NSRP'),(8592,10546,'Hsp90 protein inhibitor activity','F','OBSOLETE. Stops, prevents or reduces the activity of the Hsp90 molecular chaperone.','2013-10-27','NSRP'),(8593,10547,'thylakoid membrane disassembly','P','The controlled breakdown of the thylakoid membrane in the context of a normal process.','2013-10-27','NSRP'),(8594,10548,'regulation of thylakoid membrane disassembly','P','Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.','2013-10-27','NSRP'),(8595,10549,'regulation of membrane disassembly','P','Any process that modulates the frequency, rate or extent of membrane disassembly.','2013-10-27','NSRP'),(8596,10550,'regulation of PSII associated light-harvesting complex II catabolic process','P','Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.','2013-10-27','NSRP'),(8597,10554,'neurotransmitter secretory pathway','P','A regulated secretory pathway in which neurotransmitters are initially stored in secretory vesicles for later release.','2013-10-27','NSRP'),(8598,10555,'response to mannitol stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.','2013-10-27','NSRP'),(8599,10556,'regulation of macromolecule biosynthetic process','P','Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.','2013-10-27','NSRP'),(8600,10557,'positive regulation of macromolecule biosynthetic process','P','Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.','2013-10-27','NSRP'),(8601,10558,'negative regulation of macromolecule biosynthetic process','P','Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.','2013-10-27','NSRP'),(8602,10559,'regulation of glycoprotein biosynthetic process','P','Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.','2013-10-27','NSRP'),(8603,10560,'positive regulation of glycoprotein biosynthetic process','P','Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.','2013-10-27','NSRP'),(8604,10561,'negative regulation of glycoprotein biosynthetic process','P','Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.','2013-10-27','NSRP'),(8605,10562,'positive regulation of phosphorus metabolic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.','2013-10-27','NSRP'),(8606,10563,'negative regulation of phosphorus metabolic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.','2013-10-27','NSRP'),(8607,10564,'regulation of cell cycle process','P','Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.','2013-10-27','NSRP'),(8608,10565,'regulation of cellular ketone metabolic process','P','Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.','2013-10-27','NSRP'),(8609,10566,'regulation of ketone biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.','2013-10-27','NSRP'),(8610,10567,'regulation of ketone catabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.','2013-10-27','NSRP'),(8611,10568,'regulation of budding cell apical bud growth','P','Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.','2013-10-27','NSRP'),(8612,10569,'regulation of double-strand break repair via homologous recombination','P','Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.','2013-10-27','NSRP'),(8613,10570,'regulation of filamentous growth','P','Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.','2013-10-27','NSRP'),(8614,10571,'positive regulation of nuclear cell cycle DNA replication','P','Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.','2013-10-27','NSRP'),(8615,10572,'positive regulation of platelet activation','P','Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.','2013-10-27','NSRP'),(8616,10573,'vascular endothelial growth factor production','P','The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(8617,10574,'regulation of vascular endothelial growth factor production','P','Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.','2013-10-27','NSRP'),(8618,10575,'positive regulation vascular endothelial growth factor production','P','Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.','2013-10-27','NSRP'),(8619,10576,'metalloenzyme regulator activity','F','Modulates the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(8620,10577,'metalloenzyme activator activity','F','Increases the activity of a metalloenzyme. A metalloenzyme is any enzyme that contains metal.','2013-10-27','NSRP'),(8621,10578,'regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G-protein coupled receptor signaling pathway.','2013-10-27','NSRP'),(8622,10579,'positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway','P','Any process that increases the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G-protein coupled receptor signaling pathway.','2013-10-27','NSRP'),(8623,10581,'regulation of starch biosynthetic process','P','An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.','2013-10-27','NSRP'),(8624,10582,'floral meristem determinacy','P','The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).','2013-10-27','NSRP'),(8625,10583,'response to cyclopentenone','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.','2013-10-27','NSRP'),(8626,10584,'pollen exine formation','P','The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.','2013-10-27','NSRP'),(8627,10585,'glutamine secretion','P','The controlled release of glutamine by a cell.','2013-10-27','NSRP'),(8628,10586,'miRNA metabolic process','P','The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.','2013-10-27','NSRP'),(8629,10587,'miRNA catabolic process','P','The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.','2013-10-27','NSRP'),(8630,10588,'cotyledon vascular tissue pattern formation','P','Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.','2013-10-27','NSRP'),(8631,10589,'leaf proximal/distal pattern formation','P','The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.','2013-10-27','NSRP'),(8632,10590,'regulation of cytokinetic cell separation','P','Any process that modulates the rate, frequency or extent of the process of physically separating progeny cells contributing to cytokinesis; this may involve enzymatic digestion of septum or cell wall components.','2013-10-27','NSRP'),(8633,10591,'regulation of lamellipodium assembly','P','Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.','2013-10-27','NSRP'),(8634,10592,'positive regulation of lamellipodium assembly','P','Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.','2013-10-27','NSRP'),(8635,10593,'negative regulation of lamellipodium assembly','P','Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.','2013-10-27','NSRP'),(8636,10594,'regulation of endothelial cell migration','P','Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.','2013-10-27','NSRP'),(8637,10595,'positive regulation of endothelial cell migration','P','Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.','2013-10-27','NSRP'),(8638,10596,'negative regulation of endothelial cell migration','P','Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.','2013-10-27','NSRP'),(8639,10597,'green leaf volatile biosynthetic process','P','The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.','2013-10-27','NSRP'),(8640,10598,'NAD(P)H dehydrogenase complex (plastoquinone)','C','Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.','2013-10-27','NSRP'),(8641,10599,'production of lsiRNA involved in RNA interference','P','Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.','2013-10-27','NSRP'),(8642,10600,'regulation of auxin biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(8643,10601,'positive regulation of auxin biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.','2013-10-27','NSRP'),(8644,10602,'regulation of 1-aminocyclopropane-1-carboxylate metabolic process','P','Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.','2013-10-27','NSRP'),(8645,10603,'regulation of cytoplasmic mRNA processing body assembly','P','Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.','2013-10-27','NSRP'),(8646,10604,'positive regulation of macromolecule metabolic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.','2013-10-27','NSRP'),(8647,10605,'negative regulation of macromolecule metabolic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.','2013-10-27','NSRP'),(8648,10606,'positive regulation of cytoplasmic mRNA processing body assembly','P','Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.','2013-10-27','NSRP'),(8649,10607,'negative regulation of cytoplasmic mRNA processing body assembly','P','Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.','2013-10-27','NSRP'),(8650,10608,'posttranscriptional regulation of gene expression','P','Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.','2013-10-27','NSRP'),(8651,10609,'mRNA localization resulting in posttranscriptional regulation of gene expression','P','Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.','2013-10-27','NSRP'),(8652,10610,'regulation of mRNA stability involved in response to stress','P','Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.','2013-10-27','NSRP'),(8653,10611,'regulation of cardiac muscle hypertrophy','P','Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.','2013-10-27','NSRP'),(8654,10612,'regulation of cardiac muscle adaptation','P','Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.','2013-10-27','NSRP'),(8655,10613,'positive regulation of cardiac muscle hypertrophy','P','Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.','2013-10-27','NSRP'),(8656,10614,'negative regulation of cardiac muscle hypertrophy','P','Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.','2013-10-27','NSRP'),(8657,10615,'positive regulation of cardiac muscle adaptation','P','Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.','2013-10-27','NSRP'),(8658,10616,'negative regulation of cardiac muscle adaptation','P','Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.','2013-10-27','NSRP'),(8659,10617,'circadian regulation of calcium ion oscillation','P','Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.','2013-10-27','NSRP'),(8660,10618,'aerenchyma formation','P','The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(8661,10619,'adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway','P','The series of molecular signals generated as a consequence of glucose binding to a G-protein coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).','2013-10-27','NSRP'),(8662,10620,'negative regulation of transcription by transcription factor catabolism','P','Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.','2013-10-27','NSRP'),(8663,10621,'negative regulation of transcription by transcription factor localization','P','Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.','2013-10-27','NSRP'),(8664,10622,'specification of ovule identity','P','The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(8665,10623,'developmental programmed cell death','P','The activation of endogenous cellular processes that result in the death of a cell as part of its development.','2013-10-27','NSRP'),(8666,10624,'regulation of Schwann cell proliferation','P','Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.','2013-10-27','NSRP'),(8667,10625,'positive regulation of Schwann cell proliferation','P','Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.','2013-10-27','NSRP'),(8668,10626,'negative regulation of Schwann cell proliferation','P','Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.','2013-10-27','NSRP'),(8669,10627,'regulation of intracellular protein kinase cascade','P','Any process that modulates the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8670,10628,'positive regulation of gene expression','P','Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene\'s coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.','2013-10-27','NSRP'),(8671,10629,'negative regulation of gene expression','P','Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene\'s coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.','2013-10-27','NSRP'),(8672,10630,'regulation of transcription, start site selection','P','Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.','2013-10-27','NSRP'),(8673,10631,'epithelial cell migration','P','The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.','2013-10-27','NSRP'),(8674,10632,'regulation of epithelial cell migration','P','Any process that modulates the frequency, rate or extent of epithelial cell migration.','2013-10-27','NSRP'),(8675,10633,'negative regulation of epithelial cell migration','P','Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.','2013-10-27','NSRP'),(8676,10634,'positive regulation of epithelial cell migration','P','Any process that activates or increases the frequency, rate or extent of epithelial cell migration.','2013-10-27','NSRP'),(8677,10635,'regulation of mitochondrial fusion','P','Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.','2013-10-27','NSRP'),(8678,10636,'positive regulation of mitochondrial fusion','P','Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.','2013-10-27','NSRP'),(8679,10637,'negative regulation of mitochondrial fusion','P','Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.','2013-10-27','NSRP'),(8680,10638,'positive regulation of organelle organization','P','Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.','2013-10-27','NSRP'),(8681,10639,'negative regulation of organelle organization','P','Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.','2013-10-27','NSRP'),(8682,10640,'regulation of platelet-derived growth factor receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.','2013-10-27','NSRP'),(8683,10641,'positive regulation of platelet-derived growth factor receptor signaling pathway','P','Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.','2013-10-27','NSRP'),(8684,10642,'negative regulation of platelet-derived growth factor receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.','2013-10-27','NSRP'),(8685,10643,'cell communication by chemical coupling','P','The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8686,10644,'cell communication by electrical coupling','P','The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8687,10645,'regulation of cell communication by chemical coupling','P','Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8688,10646,'regulation of cell communication','P','Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.','2013-10-27','NSRP'),(8689,10647,'positive regulation of cell communication','P','Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.','2013-10-27','NSRP'),(8690,10648,'negative regulation of cell communication','P','Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.','2013-10-27','NSRP'),(8691,10649,'regulation of cell communication by electrical coupling','P','Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8692,10650,'positive regulation of cell communication by electrical coupling','P','Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8693,10651,'negative regulation of cell communication by electrical coupling','P','Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8694,10652,'positive regulation of cell communication by chemical coupling','P','Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8695,10653,'negative regulation of cell communication by chemical coupling','P','Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.','2013-10-27','NSRP'),(8696,10654,'apical cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.','2013-10-27','NSRP'),(8697,10656,'negative regulation of muscle cell apoptotic process','P','Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.','2013-10-27','NSRP'),(8698,10657,'muscle cell apoptotic process','P','A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.','2013-10-27','NSRP'),(8699,10658,'striated muscle cell apoptotic process','P','A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.','2013-10-27','NSRP'),(8700,10659,'cardiac muscle cell apoptotic process','P','A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.','2013-10-27','NSRP'),(8701,10660,'regulation of muscle cell apoptotic process','P','Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.','2013-10-27','NSRP'),(8702,10661,'positive regulation of muscle cell apoptotic process','P','Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.','2013-10-27','NSRP'),(8703,10662,'regulation of striated muscle cell apoptotic process','P','Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.','2013-10-27','NSRP'),(8704,10663,'positive regulation of striated muscle cell apoptotic process','P','Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.','2013-10-27','NSRP'),(8705,10664,'negative regulation of striated muscle cell apoptotic process','P','Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.','2013-10-27','NSRP'),(8706,10665,'regulation of cardiac muscle cell apoptotic process','P','Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.','2013-10-27','NSRP'),(8707,10666,'positive regulation of cardiac muscle cell apoptotic process','P','Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.','2013-10-27','NSRP'),(8708,10667,'negative regulation of cardiac muscle cell apoptotic process','P','Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.','2013-10-27','NSRP'),(8709,10668,'ectodermal cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.','2013-10-27','NSRP'),(8710,10669,'epithelial structure maintenance','P','A tissue homeostatic process required for the maintenance of epithelial structure.','2013-10-27','NSRP'),(8711,10670,'positive regulation of oxygen and reactive oxygen species metabolic process','P','OBSOLETE. Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).','2013-10-27','NSRP'),(8712,10671,'negative regulation of oxygen and reactive oxygen species metabolic process','P','OBSOLETE. Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving dioxygen (O2), or any of the reactive oxygen species, e.g. superoxide anions (O2-), hydrogen peroxide (H2O2), and hydroxyl radicals (-OH).','2013-10-27','NSRP'),(8713,10672,'regulation of transcription from RNA polymerase II promoter during meiosis','P','A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter during meiosis.','2013-10-27','NSRP'),(8714,10673,'positive regulation of transcription from RNA polymerase II promoter during meiosis','P','A cell cycle process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter during meiosis.','2013-10-27','NSRP'),(8715,10674,'negative regulation of transcription from RNA polymerase II promoter during meiosis','P','A cell cycle process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter during meiosis.','2013-10-27','NSRP'),(8716,10675,'regulation of cellular carbohydrate metabolic process','P','Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.','2013-10-27','NSRP'),(8717,10676,'positive regulation of cellular carbohydrate metabolic process','P','Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.','2013-10-27','NSRP'),(8718,10677,'negative regulation of cellular carbohydrate metabolic process','P','Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.','2013-10-27','NSRP'),(8719,10678,'negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent','P','Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription.','2013-10-27','NSRP'),(8720,10679,'cinnamic acid biosynthetic process involved in salicylic acid metabolism','P','The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.','2013-10-27','NSRP'),(8721,10680,'cinnamic acid biosynthetic process involved in coumarin metabolism','P','The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.','2013-10-27','NSRP'),(8722,10681,'cinnamic acid biosynthetic process involved in stilbene metabolism','P','The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.','2013-10-27','NSRP'),(8723,10682,'cinnamic acid biosynthetic process involved in flavonoid metabolism','P','The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.','2013-10-27','NSRP'),(8724,10683,'tricyclic triterpenoid metabolic process','P','The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.','2013-10-27','NSRP'),(8725,10684,'tricyclic triterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.','2013-10-27','NSRP'),(8726,10685,'tetracyclic triterpenoid metabolic process','P','The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.','2013-10-27','NSRP'),(8727,10686,'tetracyclic triterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.','2013-10-27','NSRP'),(8728,10687,'site selection involved in cell cycle cytokinesis','P','The process of marking the place where cytokinesis will occur in the context of cell cycle progression.','2013-04-22','NSRP'),(8729,10688,'negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter','P','Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.','2013-10-27','NSRP'),(8730,10689,'negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus','P','Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.','2013-10-27','NSRP'),(8731,10690,'negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress','P','Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.','2013-10-27','NSRP'),(8732,10691,'negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels','P','Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.','2013-10-27','NSRP'),(8733,10692,'regulation of alkaline phosphatase activity','P','Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.','2013-10-27','NSRP'),(8734,10693,'negative regulation of alkaline phosphatase activity','P','Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.','2013-10-27','NSRP'),(8735,10694,'positive regulation of alkaline phosphatase activity','P','Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.','2013-10-27','NSRP'),(8736,10695,'regulation of spindle pole body separation','P','Any process that modulates the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.','2013-10-27','NSRP'),(8737,10696,'positive regulation of spindle pole body separation','P','Any process that increases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.','2013-10-27','NSRP'),(8738,10697,'negative regulation of spindle pole body separation','P','Any process that decreases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.','2013-10-27','NSRP'),(8739,10698,'acetyltransferase activator activity','F','Increases the activity of an aceyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.','2013-10-27','NSRP'),(8740,10699,'cell-cell signaling involved in quorum sensing','P','The cell-cell signaling process in which single-celled organisms monitor population density by detecting the concentration of small diffusible signal molecules.','2013-10-27','NSRP'),(8741,10700,'negative regulation of norepinephrine secretion','P','Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.','2013-10-27','NSRP'),(8742,10701,'positive regulation of norepinephrine secretion','P','Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.','2013-10-27','NSRP'),(8743,10702,'regulation of histolysis','P','Any process that modulates the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.','2013-10-27','NSRP'),(8744,10703,'negative regulation of histolysis','P','Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.','2013-10-27','NSRP'),(8745,10704,'meiotic DNA double-strand break processing involved in meiotic gene conversion','P','The cell cycle process in which the 5\' to 3\' exonucleolytic resection of the DNA at the site of the break to form a 3\' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.','2013-10-27','NSRP'),(8746,10705,'meiotic DNA double-strand break processing involved in reciprocal meiotic recombination','P','The cell cycle process in which the 5\' to 3\' exonucleolytic resection of the DNA at the site of the break to form a 3\' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8747,10706,'ganglioside biosynthetic process via lactosylceramide','P','The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1\') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.','2013-10-27','NSRP'),(8748,10707,'globoside biosynthetic process via lactosylceramide','P','The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1\') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.','2013-10-27','NSRP'),(8749,10708,'heteroduplex formation involved in gene conversion at mating-type locus','P','The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the conversion of the mating-type locus from one allele to another.','2013-10-27','NSRP'),(8750,10709,'heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing','P','The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.','2013-10-27','NSRP'),(8751,10710,'regulation of collagen catabolic process','P','Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.','2013-10-27','NSRP'),(8752,10711,'negative regulation of collagen catabolic process','P','Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.','2013-10-27','NSRP'),(8753,10712,'regulation of collagen metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.','2013-10-27','NSRP'),(8754,10713,'negative regulation of collagen metabolic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.','2013-10-27','NSRP'),(8755,10714,'positive regulation of collagen metabolic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.','2013-10-27','NSRP'),(8756,10715,'regulation of extracellular matrix disassembly','P','Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.','2013-10-27','NSRP'),(8757,10716,'negative regulation of extracellular matrix disassembly','P','Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.','2013-10-27','NSRP'),(8758,10717,'regulation of epithelial to mesenchymal transition','P','Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.','2013-10-27','NSRP'),(8759,10718,'positive regulation of epithelial to mesenchymal transition','P','Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.','2013-10-27','NSRP'),(8760,10719,'negative regulation of epithelial to mesenchymal transition','P','Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.','2013-10-27','NSRP'),(8761,10720,'positive regulation of cell development','P','Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.','2013-10-27','NSRP'),(8762,10721,'negative regulation of cell development','P','Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.','2013-10-27','NSRP'),(8763,10722,'regulation of ferrochelatase activity','P','Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.','2013-10-27','NSRP'),(8764,10723,'positive regulation of transcription from RNA polymerase II promoter in response to iron','P','Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.','2013-10-27','NSRP'),(8765,10724,'regulation of definitive erythrocyte differentiation','P','Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.','2013-10-27','NSRP'),(8766,10725,'regulation of primitive erythrocyte differentiation','P','Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.','2013-10-27','NSRP'),(8767,10726,'positive regulation of hydrogen peroxide metabolic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.','2013-10-27','NSRP'),(8768,10727,'negative regulation of hydrogen peroxide metabolic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.','2013-10-27','NSRP'),(8769,10728,'regulation of hydrogen peroxide biosynthetic process','P','Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.','2013-10-27','NSRP'),(8770,10729,'positive regulation of hydrogen peroxide biosynthetic process','P','Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.','2013-10-27','NSRP'),(8771,10730,'negative regulation of hydrogen peroxide biosynthetic process','P','Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.','2013-10-27','NSRP'),(8772,10731,'protein glutathionylation','P','The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.','2013-10-27','NSRP'),(8773,10732,'regulation of protein glutathionylation','P','Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.','2013-10-27','NSRP'),(8774,10733,'positive regulation of protein glutathionylation','P','Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.','2013-10-27','NSRP'),(8775,10734,'negative regulation of protein glutathionylation','P','Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.','2013-10-27','NSRP'),(8776,10735,'positive regulation of transcription via serum response element binding','P','Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.','2013-10-27','NSRP'),(8777,10736,'serum response element binding','F','Interacting selectively and non-covalently with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.','2013-10-27','NSRP'),(8778,10737,'protein kinase A signaling cascade','P','A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8779,10738,'regulation of protein kinase A signaling cascade','P','Any process that modulates the rate, frequency, or extent of the protein kinase A signaling cascade. The PKA signaling cascade is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8780,10739,'positive regulation of protein kinase A signaling cascade','P','Any process that increases the rate, frequency, or extent of the protein kinase A signaling cascade. The PKA signaling cascade is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8781,10740,'positive regulation of intracellular protein kinase cascade','P','Any process that increases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8782,10741,'negative regulation of intracellular protein kinase cascade','P','Any process that decreases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(8783,10742,'macrophage derived foam cell differentiation','P','The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.','2013-10-27','NSRP'),(8784,10743,'regulation of macrophage derived foam cell differentiation','P','Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.','2013-10-27','NSRP'),(8785,10744,'positive regulation of macrophage derived foam cell differentiation','P','Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.','2013-10-27','NSRP'),(8786,10745,'negative regulation of macrophage derived foam cell differentiation','P','Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.','2013-10-27','NSRP'),(8787,10746,'regulation of plasma membrane long-chain fatty acid transport','P','Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(8788,10747,'positive regulation of plasma membrane long-chain fatty acid transport','P','Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(8789,10748,'negative regulation of plasma membrane long-chain fatty acid transport','P','Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.','2013-10-27','NSRP'),(8790,10749,'regulation of nitric oxide mediated signal transduction','P','Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).','2013-10-27','NSRP'),(8791,10750,'positive regulation of nitric oxide mediated signal transduction','P','Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).','2013-10-27','NSRP'),(8792,10751,'negative regulation of nitric oxide mediated signal transduction','P','Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).','2013-10-27','NSRP'),(8793,10752,'regulation of cGMP-mediated signaling','P','Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.','2013-10-27','NSRP'),(8794,10753,'positive regulation of cGMP-mediated signaling','P','Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.','2013-10-27','NSRP'),(8795,10754,'negative regulation of cGMP-mediated signaling','P','Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.','2013-10-27','NSRP'),(8796,10755,'regulation of plasminogen activation','P','Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.','2013-10-27','NSRP'),(8797,10756,'positive regulation of plasminogen activation','P','Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.','2013-10-27','NSRP'),(8798,10757,'negative regulation of plasminogen activation','P','Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.','2013-10-27','NSRP'),(8799,10758,'regulation of macrophage chemotaxis','P','Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.','2013-10-27','NSRP'),(8800,10759,'positive regulation of macrophage chemotaxis','P','Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.','2013-10-27','NSRP'),(8801,10760,'negative regulation of macrophage chemotaxis','P','Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.','2013-10-27','NSRP'),(8802,10761,'fibroblast migration','P','Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(8803,10762,'regulation of fibroblast migration','P','Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.','2013-10-27','NSRP'),(8804,10763,'positive regulation of fibroblast migration','P','Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.','2013-10-27','NSRP'),(8805,10764,'negative regulation of fibroblast migration','P','Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.','2013-10-27','NSRP'),(8806,10765,'positive regulation of sodium ion transport','P','Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8807,10766,'negative regulation of sodium ion transport','P','Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8808,10767,'regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.','2013-10-27','NSRP'),(8809,10768,'negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.','2013-10-27','NSRP'),(8810,10769,'regulation of cell morphogenesis involved in differentiation','P','Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism\'s life history.','2013-10-27','NSRP'),(8811,10770,'positive regulation of cell morphogenesis involved in differentiation','P','Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism\'s life history.','2013-10-27','NSRP'),(8812,10771,'negative regulation of cell morphogenesis involved in differentiation','P','Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism\'s life history.','2013-10-27','NSRP'),(8813,10772,'meiotic DNA recombinase assembly involved in reciprocal meiotic recombination','P','The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8814,10773,'meiotic DNA recombinase assembly involved in meiotic gene conversion','P','The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.','2013-10-27','NSRP'),(8815,10774,'meiotic strand invasion involved in reciprocal meiotic recombination','P','The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8816,10775,'meiotic strand invasion involved in meiotic gene conversion','P','The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.','2013-10-27','NSRP'),(8817,10776,'meiotic mismatch repair involved in meiotic gene conversion','P','A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.','2013-10-27','NSRP'),(8818,10777,'meiotic mismatch repair involved in reciprocal meiotic recombination','P','A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8819,10778,'meiotic DNA repair synthesis involved in reciprocal meiotic recombination','P','The synthesis of DNA proceeding from the broken 3\' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8820,10779,'meiotic DNA repair synthesis involved in meiotic gene conversion','P','The synthesis of DNA proceeding from the broken 3\' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.','2013-10-27','NSRP'),(8821,10780,'meiotic DNA double-strand break formation involved in reciprocal meiotic recombination','P','The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8822,10781,'meiotic DNA double-strand break formation involved in meiotic gene conversion','P','The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.','2013-10-27','NSRP'),(8823,10782,'proboscis morphogenesis, labial disc-derived','P','The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.','2013-10-27','NSRP'),(8824,10783,'proboscis morphogenesis, eye-antennal disc-derived','P','The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.','2013-10-27','NSRP'),(8825,10784,'proboscis morphogenesis, clypeo-labral disc-derived','P','The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.','2013-10-27','NSRP'),(8826,10785,'clathrin coating of Golgi vesicle, plasma membrane to endosome targeting','P','The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.','2013-10-27','NSRP'),(8827,10786,'clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting','P','The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.','2013-10-27','NSRP'),(8828,10787,'COPI coating of Golgi vesicle, inter-Golgi cisterna','P','The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.','2013-10-27','NSRP'),(8829,10788,'COPI coating of Golgi vesicle, cis-Golgi to rough ER','P','The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.','2013-10-27','NSRP'),(8830,10789,'meiotic sister chromatid cohesion involved in meiosis I','P','The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.','2013-10-27','NSRP'),(8831,10790,'meiotic sister chromatid cohesion involved in meiosis II','P','The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.','2013-10-27','NSRP'),(8832,10791,'DNA double-strand break processing involved in repair via synthesis-dependent strand annealing','P','The 5\' to 3\' exonucleolytic resection of the DNA at the site of the break to form a 3\' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.','2013-10-27','NSRP'),(8833,10792,'DNA double-strand break processing involved in repair via single-strand annealing','P','The 5\' to 3\' exonucleolytic resection of the DNA at the site of the break to form a 3\' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.','2013-10-27','NSRP'),(8834,10793,'regulation of mRNA export from nucleus','P','Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.','2013-10-27','NSRP'),(8835,10794,'regulation of dolichol biosynthetic process','P','Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.','2013-10-27','NSRP'),(8836,10795,'regulation of ubiquinone biosynthetic process','P','Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.','2013-10-27','NSRP'),(8837,10796,'regulation of multivesicular body size','P','Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.','2013-10-27','NSRP'),(8838,10797,'regulation of multivesicular body size involved in endosome transport','P','Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.','2013-10-27','NSRP'),(8839,10798,'regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism','P','Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.','2013-10-27','NSRP'),(8840,10799,'regulation of peptidyl-threonine phosphorylation','P','Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.','2013-10-27','NSRP'),(8841,10800,'positive regulation of peptidyl-threonine phosphorylation','P','Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.','2013-10-27','NSRP'),(8842,10801,'negative regulation of peptidyl-threonine phosphorylation','P','Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.','2013-10-27','NSRP'),(8843,10803,'regulation of tumor necrosis factor-mediated signaling pathway','P','Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.','2013-10-27','NSRP'),(8844,10804,'negative regulation of tumor necrosis factor-mediated signaling pathway','P','Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.','2013-10-27','NSRP'),(8845,10805,'regulation of lysine import','P','Any process that modulates the rate or frequency of lysine import. Lysine import is the directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.','2013-10-27','NSRP'),(8846,10806,'negative regulation of lysine import','P','Any process that decreases the rate or frequency of lysine import. Lysine import is the directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.','2013-10-27','NSRP'),(8847,10807,'regulation of synaptic vesicle priming','P','Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.','2013-10-27','NSRP'),(8848,10808,'positive regulation of synaptic vesicle priming','P','Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.','2013-10-27','NSRP'),(8849,10809,'negative regulation of synaptic vesicle priming','P','Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.','2013-10-27','NSRP'),(8850,10810,'regulation of cell-substrate adhesion','P','Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.','2013-10-27','NSRP'),(8851,10811,'positive regulation of cell-substrate adhesion','P','Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.','2013-10-27','NSRP'),(8852,10812,'negative regulation of cell-substrate adhesion','P','Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.','2013-10-27','NSRP'),(8853,10813,'neuropeptide catabolic process','P','The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.','2013-10-27','NSRP'),(8854,10814,'substance P catabolic process','P','The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.','2013-10-27','NSRP'),(8855,10815,'bradykinin catabolic process','P','The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.','2013-10-27','NSRP'),(8856,10816,'calcitonin catabolic process','P','The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.','2013-10-27','NSRP'),(8857,10817,'regulation of hormone levels','P','Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.','2013-10-27','NSRP'),(8858,10818,'T cell chemotaxis','P','The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.','2013-10-27','NSRP'),(8859,10819,'regulation of T cell chemotaxis','P','Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.','2013-10-27','NSRP'),(8860,10820,'positive regulation of T cell chemotaxis','P','Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.','2013-10-27','NSRP'),(8861,10821,'regulation of mitochondrion organization','P','Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.','2013-10-27','NSRP'),(8862,10822,'positive regulation of mitochondrion organization','P','Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.','2013-10-27','NSRP'),(8863,10823,'negative regulation of mitochondrion organization','P','Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.','2013-10-27','NSRP'),(8864,10824,'regulation of centrosome duplication','P','Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.','2013-10-27','NSRP'),(8865,10825,'positive regulation of centrosome duplication','P','Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.','2013-10-27','NSRP'),(8866,10826,'negative regulation of centrosome duplication','P','Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.','2013-10-27','NSRP'),(8867,10827,'regulation of glucose transport','P','Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8868,10828,'positive regulation of glucose transport','P','Any process that increases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8869,10829,'negative regulation of glucose transport','P','Any process that decreases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8870,10830,'regulation of myotube differentiation','P','Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(8871,10831,'positive regulation of myotube differentiation','P','Any process that increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(8872,10832,'negative regulation of myotube differentiation','P','Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(8873,10833,'telomere maintenance via telomere lengthening','P','Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.','2013-10-27','NSRP'),(8874,10834,'telomere maintenance via telomere shortening','P','Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA.','2013-10-27','NSRP'),(8875,10835,'regulation of protein ADP-ribosylation','P','Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.','2013-10-27','NSRP'),(8876,10836,'negative regulation of protein ADP-ribosylation','P','Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.','2013-10-27','NSRP'),(8877,10837,'regulation of keratinocyte proliferation','P','Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.','2013-10-27','NSRP'),(8878,10838,'positive regulation of keratinocyte proliferation','P','Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.','2013-10-27','NSRP'),(8879,10839,'negative regulation of keratinocyte proliferation','P','Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.','2013-10-27','NSRP'),(8880,10840,'regulation of circadian sleep/wake cycle, wakefulness','P','Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.','2013-10-27','NSRP'),(8881,10841,'positive regulation of circadian sleep/wake cycle, wakefulness','P','Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.','2013-10-27','NSRP'),(8882,10842,'retina layer formation','P','The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.','2013-10-27','NSRP'),(8883,10843,'promoter binding','F','OBSOLETE. Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.','2013-10-27','NSRP'),(8884,10844,'recombination hotspot binding','F','Interacting selectively and non-covalently with a region in a genome which promotes recombination.','2013-10-27','NSRP'),(8885,10845,'positive regulation of reciprocal meiotic recombination','P','Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8886,10846,'activation of reciprocal meiotic recombination','P','Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.','2013-10-27','NSRP'),(8887,10847,'regulation of chromatin assembly','P','Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.','2013-10-27','NSRP'),(8888,10848,'regulation of chromatin disassembly','P','Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.','2013-10-27','NSRP'),(8889,10849,'regulation of proton-transporting ATPase activity, rotational mechanism','P','Any process that modulates the rate of ATP hydrolysis by an ATPase. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.','2013-10-27','NSRP'),(8890,10850,'regulation of blood pressure by chemoreceptor signaling pathway','P','A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.','2013-10-27','NSRP'),(8891,10851,'cyclase regulator activity','F','Modulates the activity of an enzyme that catalyzes a ring closure reaction.','2013-10-27','NSRP'),(8892,10852,'cyclase inhibitor activity','F','Decreases the activity of an enzyme that catalyzes a ring closure reaction.','2013-10-27','NSRP'),(8893,10853,'cyclase activator activity','F','Increases the activity of an enzyme that catalyzes a ring closure reaction.','2013-10-27','NSRP'),(8894,10854,'adenylate cyclase regulator activity','F','Modulates the activity of the enzyme that catalyzes the reaction: ATP = 3\',5\'-cyclic AMP + diphosphate.','2013-10-27','NSRP'),(8895,10855,'adenylate cyclase inhibitor activity','F','Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3\',5\'-cyclic AMP + diphosphate.','2013-10-27','NSRP'),(8896,10856,'adenylate cyclase activator activity','F','Increases the activity of the enzyme that catalyzes the reaction: ATP = 3\',5\'-cyclic AMP + diphosphate.','2013-10-27','NSRP'),(8897,10857,'calcium-dependent protein kinase activity','F','Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium.','2013-10-27','NSRP'),(8898,10858,'calcium-dependent protein kinase regulator activity','F','Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.','2013-10-27','NSRP'),(8899,10859,'calcium-dependent cysteine-type endopeptidase inhibitor activity','F','Stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.','2013-10-27','NSRP'),(8900,10860,'proteasome regulator activity','F','OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.','2013-10-27','NSRP'),(8901,10861,'thyroid hormone receptor activator activity','F','A receptor activator activity that binds to, thyroid hormone receptor in a ligand-dependent manner and enhances ligand-induced transcriptional activity of the receptor.','2013-10-27','NSRP'),(8902,10862,'positive regulation of pathway-restricted SMAD protein phosphorylation','P','Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(8903,10863,'positive regulation of phospholipase C activity','P','Any process that increases the rate of phospholipase C activity.','2013-10-27','NSRP'),(8904,10864,'positive regulation of protein histidine kinase activity','P','Any process that increases the frequency, rate or extent of protein histidine kinase activity.','2013-10-27','NSRP'),(8905,10865,'stipule development','P','The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.','2013-10-27','NSRP'),(8906,10866,'regulation of triglyceride biosynthetic process','P','Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.','2013-10-27','NSRP'),(8907,10867,'positive regulation of triglyceride biosynthetic process','P','Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.','2013-10-27','NSRP'),(8908,10868,'negative regulation of triglyceride biosynthetic process','P','Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.','2013-10-27','NSRP'),(8909,10869,'regulation of receptor biosynthetic process','P','Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.','2013-10-27','NSRP'),(8910,10870,'positive regulation of receptor biosynthetic process','P','Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.','2013-10-27','NSRP'),(8911,10871,'negative regulation of receptor biosynthetic process','P','Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.','2013-10-27','NSRP'),(8912,10872,'regulation of cholesterol esterification','P','Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.','2013-10-27','NSRP'),(8913,10873,'positive regulation of cholesterol esterification','P','Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.','2013-10-27','NSRP'),(8914,10874,'regulation of cholesterol efflux','P','Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.','2013-10-27','NSRP'),(8915,10875,'positive regulation of cholesterol efflux','P','Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.','2013-10-27','NSRP'),(8916,10876,'lipid localization','P','Any process in which a lipid is transported to, or maintained in, a specific location.','2013-10-27','NSRP'),(8917,10877,'lipid transport involved in lipid storage','P','The directed movement of lipids into cells that is part of their accumulation and maintenance.','2013-10-27','NSRP'),(8918,10878,'cholesterol storage','P','The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(8919,10879,'cholesterol transport involved in cholesterol storage','P','The directed movement of cholesterol into cells that is part of their accumulation and maintenance.','2013-10-27','NSRP'),(8920,10880,'regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum','P','Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.','2013-10-27','NSRP'),(8921,10881,'regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion','P','Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.','2013-10-27','NSRP'),(8922,10882,'regulation of cardiac muscle contraction by calcium ion signaling','P','Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.','2013-10-27','NSRP'),(8923,10883,'regulation of lipid storage','P','Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.','2013-10-27','NSRP'),(8924,10884,'positive regulation of lipid storage','P','Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.','2013-10-27','NSRP'),(8925,10885,'regulation of cholesterol storage','P','Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(8926,10886,'positive regulation of cholesterol storage','P','Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(8927,10887,'negative regulation of cholesterol storage','P','Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(8928,10888,'negative regulation of lipid storage','P','Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.','2013-10-27','NSRP'),(8929,10889,'regulation of sequestering of triglyceride','P','Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.','2013-10-27','NSRP'),(8930,10890,'positive regulation of sequestering of triglyceride','P','Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.','2013-10-27','NSRP'),(8931,10891,'negative regulation of sequestering of triglyceride','P','Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.','2013-10-27','NSRP'),(8932,10892,'positive regulation of mitochondrial translation in response to stress','P','Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.','2013-10-27','NSRP'),(8933,10893,'positive regulation of steroid biosynthetic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.','2013-10-27','NSRP'),(8934,10894,'negative regulation of steroid biosynthetic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.','2013-10-27','NSRP'),(8935,10895,'negative regulation of ergosterol biosynthetic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.','2013-10-27','NSRP'),(8936,10896,'regulation of triglyceride catabolic process','P','Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.','2013-10-27','NSRP'),(8937,10897,'negative regulation of triglyceride catabolic process','P','Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.','2013-10-27','NSRP'),(8938,10898,'positive regulation of triglyceride catabolic process','P','Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.','2013-10-27','NSRP'),(8939,10899,'regulation of phosphatidylcholine catabolic process','P','Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.','2013-10-27','NSRP'),(8940,10900,'negative regulation of phosphatidylcholine catabolic process','P','Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.','2013-10-27','NSRP'),(8941,10901,'regulation of very-low-density lipoprotein particle remodeling','P','Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.','2013-10-27','NSRP'),(8942,10902,'positive regulation of very-low-density lipoprotein particle remodeling','P','Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.','2013-10-27','NSRP'),(8943,10903,'negative regulation of very-low-density lipoprotein particle remodeling','P','Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.','2013-10-27','NSRP'),(8944,10904,'regulation of UDP-glucose catabolic process','P','Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(8945,10905,'negative regulation of UDP-glucose catabolic process','P','Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(8946,10906,'regulation of glucose metabolic process','P','Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.','2013-10-27','NSRP'),(8947,10907,'positive regulation of glucose metabolic process','P','Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.','2013-10-27','NSRP'),(8948,10908,'regulation of heparan sulfate proteoglycan biosynthetic process','P','Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.','2013-10-27','NSRP'),(8949,10909,'positive regulation of heparan sulfate proteoglycan biosynthetic process','P','Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.','2013-10-27','NSRP'),(8950,10910,'positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity','P','Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.','2013-10-27','NSRP'),(8951,10911,'regulation of isomerase activity','P','Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.','2013-10-27','NSRP'),(8952,10912,'positive regulation of isomerase activity','P','Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.','2013-10-27','NSRP'),(8953,10913,'regulation of sterigmatocystin biosynthetic process','P','Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.','2013-10-27','NSRP'),(8954,10914,'positive regulation of sterigmatocystin biosynthetic process','P','Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.','2013-10-27','NSRP'),(8955,10915,'regulation of very-low-density lipoprotein particle clearance','P','Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(8956,10916,'negative regulation of very-low-density lipoprotein particle clearance','P','Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(8957,10917,'negative regulation of mitochondrial membrane potential','P','Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.','2013-10-27','NSRP'),(8958,10918,'positive regulation of mitochondrial membrane potential','P','Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.','2013-10-27','NSRP'),(8959,10919,'regulation of inositol phosphate biosynthetic process','P','Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.','2013-10-27','NSRP'),(8960,10920,'negative regulation of inositol phosphate biosynthetic process','P','Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.','2013-10-27','NSRP'),(8961,10921,'regulation of phosphatase activity','P','Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.','2013-10-27','NSRP'),(8962,10922,'positive regulation of phosphatase activity','P','Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.','2013-10-27','NSRP'),(8963,10923,'negative regulation of phosphatase activity','P','Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.','2013-10-27','NSRP'),(8964,10924,'regulation of inositol-polyphosphate 5-phosphatase activity','P','Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.','2013-10-27','NSRP'),(8965,10925,'positive regulation of inositol-polyphosphate 5-phosphatase activity','P','Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.','2013-10-27','NSRP'),(8966,10926,'anatomical structure formation','P','OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.','2013-10-27','NSRP'),(8967,10927,'cellular component assembly involved in morphogenesis','P','The cellular component assembly that is part of the initial shaping of the component during its developmental progression.','2013-10-27','NSRP'),(8968,10928,'regulation of auxin mediated signaling pathway','P','Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.','2013-10-27','NSRP'),(8969,10929,'positive regulation of auxin mediated signaling pathway','P','Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.','2013-10-27','NSRP'),(8970,10930,'negative regulation of auxin mediated signaling pathway','P','Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.','2013-10-27','NSRP'),(8971,10931,'macrophage tolerance induction','P','A process involving any mechanism for tolerance induction in macrophages.','2013-10-27','NSRP'),(8972,10932,'regulation of macrophage tolerance induction','P','Any process that modulates the frequency, rate, or extent of B cell tolerance induction.','2013-10-27','NSRP'),(8973,10933,'positive regulation of macrophage tolerance induction','P','Any process that increases the frequency, rate, or extent of B cell tolerance induction.','2013-10-27','NSRP'),(8974,10934,'macrophage cytokine production','P','The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(8975,10935,'regulation of macrophage cytokine production','P','Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(8976,10936,'negative regulation of macrophage cytokine production','P','Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(8977,10937,'regulation of cytoplasmic microtubule depolymerization','P','Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.','2013-10-27','NSRP'),(8978,10938,'cytoplasmic microtubule depolymerization','P','The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.','2013-10-27','NSRP'),(8979,10939,'regulation of necrotic cell death','P','Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.','2013-10-27','NSRP'),(8980,10940,'positive regulation of necrotic cell death','P','Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.','2013-10-27','NSRP'),(8981,10941,'regulation of cell death','P','Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.','2013-10-27','NSRP'),(8982,10942,'positive regulation of cell death','P','Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.','2013-10-27','NSRP'),(8983,10943,'NADPH pyrophosphatase activity','F','Catalysis of the reaction: NADPH + H2O = NMNH + ADP.','2013-10-27','NSRP'),(8984,10944,'negative regulation of transcription by competitive promoter binding','P','Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.','2013-10-27','NSRP'),(8985,10945,'CoA pyrophosphatase activity','F','Catalysis of the reaction: coenzyme A + H2O = 3\',5\'-ADP + 4\'-phosphopantetheine.','2013-10-27','NSRP'),(8986,10946,'regulation of meiotic joint molecule formation','P','Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.','2013-10-27','NSRP'),(8987,10947,'negative regulation of meiotic joint molecule formation','P','Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.','2013-10-27','NSRP'),(8988,10948,'negative regulation of cell cycle process','P','Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.','2013-10-27','NSRP'),(8989,10949,'negative regulation of intestinal phytosterol absorption','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.','2013-10-27','NSRP'),(8990,10950,'positive regulation of endopeptidase activity','P','Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.','2013-10-27','NSRP'),(8991,10951,'negative regulation of endopeptidase activity','P','Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.','2013-10-27','NSRP'),(8992,10952,'positive regulation of peptidase activity','P','Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.','2013-10-27','NSRP'),(8993,10954,'positive regulation of protein processing','P','Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.','2013-10-27','NSRP'),(8994,10955,'negative regulation of protein processing','P','Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.','2013-10-27','NSRP'),(8995,10956,'negative regulation of calcidiol 1-monooxygenase activity','P','Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.','2013-10-27','NSRP'),(8996,10957,'negative regulation of vitamin D biosynthetic process','P','Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).','2013-10-27','NSRP'),(8997,10958,'regulation of amino acid import','P','Any process that modulates the frequency, rate or extent of amino acid import. Amino acid import is the directed movement of amino acids into a cell or organelle.','2013-10-27','NSRP'),(8998,10959,'regulation of metal ion transport','P','Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(8999,10960,'magnesium ion homeostasis','P','Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.','2013-10-27','NSRP'),(9000,10961,'cellular magnesium ion homeostasis','P','Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell.','2013-10-27','NSRP'),(9001,10962,'regulation of glucan biosynthetic process','P','Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.','2013-10-27','NSRP'),(9002,10963,'regulation of L-arginine import','P','Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle.','2013-10-27','NSRP'),(9003,10964,'regulation of chromatin silencing by small RNA','P','Any process that modulates the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.','2013-10-27','NSRP'),(9004,10965,'regulation of mitotic sister chromatid separation','P','Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.','2013-10-27','NSRP'),(9005,10966,'regulation of phosphate transport','P','Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9006,10967,'regulation of polyamine biosynthetic process','P','Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.','2013-10-27','NSRP'),(9007,10968,'regulation of microtubule nucleation','P','Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the \'de novo\' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.','2013-10-27','NSRP'),(9008,10969,'regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion','P','Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.','2013-10-27','NSRP'),(9009,10970,'microtubule-based transport','P','Microtubule-based movement that results in the net, directed movement of organelles or other particles from one location in the cell to another.','2013-10-27','NSRP'),(9010,10971,'positive regulation of G2/M transition of mitotic cell cycle','P','Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.','2013-10-27','NSRP'),(9011,10972,'negative regulation of G2/M transition of mitotic cell cycle','P','Any cell cycle regulatory process that decreases the rate or extent of progression of a cell from G2 to M phase of the mitotic cell cycle.','2013-10-27','NSRP'),(9012,10973,'positive regulation of barrier septum assembly','P','Any process that increases the frequency, rate or extent of barrier septum formation. Barrier septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.','2013-10-27','NSRP'),(9013,10974,'negative regulation of barrier septum assembly','P','Any process that decreases the frequency, rate or extent of barrier septum formation. Barrier septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.','2013-10-27','NSRP'),(9014,10975,'regulation of neuron projection development','P','Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).','2013-10-27','NSRP'),(9015,10976,'positive regulation of neuron projection development','P','Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).','2013-10-27','NSRP'),(9016,10977,'negative regulation of neuron projection development','P','Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).','2013-10-27','NSRP'),(9017,10978,'gene silencing involved in chronological cell aging','P','Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.','2013-10-27','NSRP'),(9018,10979,'regulation of vitamin D 24-hydroxylase activity','P','Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.','2013-10-27','NSRP'),(9019,10980,'positive regulation of vitamin D 24-hydroxylase activity','P','Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.','2013-10-27','NSRP'),(9020,10981,'regulation of cell wall macromolecule metabolic process','P','Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.','2013-10-27','NSRP'),(9021,10982,'regulation of high-density lipoprotein particle clearance','P','Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9022,10983,'positive regulation of high-density lipoprotein particle clearance','P','Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9023,10984,'regulation of lipoprotein particle clearance','P','Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9024,10985,'negative regulation of lipoprotein particle clearance','P','Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9025,10986,'positive regulation of lipoprotein particle clearance','P','Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9026,10987,'negative regulation of high-density lipoprotein particle clearance','P','Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9027,10988,'regulation of low-density lipoprotein particle clearance','P','Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9028,10989,'negative regulation of low-density lipoprotein particle clearance','P','Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.','2013-10-27','NSRP'),(9029,10990,'regulation of SMAD protein complex assembly','P','Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.','2013-10-27','NSRP'),(9030,10991,'negative regulation of SMAD protein complex assembly','P','Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.','2013-10-27','NSRP'),(9031,10992,'ubiquitin homeostasis','P','Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell.','2013-10-27','NSRP'),(9032,10993,'regulation of ubiquitin homeostasis','P','Any process that modulates the rate, frequency, or extent of ubiquitin homeostasis. Ubiquitin homeostasis is any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell.','2013-10-27','NSRP'),(9033,10994,'free ubiquitin chain polymerization','P','The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.','2013-10-27','NSRP'),(9034,10995,'free ubiquitin chain depolymerization','P','The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.','2013-10-27','NSRP'),(9035,10996,'response to auditory stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.','2013-10-27','NSRP'),(9036,10997,'anaphase-promoting complex binding','F','Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.','2013-10-27','NSRP'),(9037,10998,'regulation of translational initiation by eIF2 alpha phosphorylation','P','Any process that activates or increases the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.','2013-10-27','NSRP'),(9038,10999,'regulation of eIF2 alpha phosphorylation by heme','P','Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.','2013-10-27','NSRP'),(9039,11000,'replication fork arrest at mating type locus','P','A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.','2013-10-27','NSRP'),(9040,12501,'programmed cell death','P','A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.','2013-10-27','NSRP'),(9041,12502,'induction of programmed cell death','P','A process which directly activates any of the steps required for programmed cell death.','2013-10-27','NSRP'),(9042,12505,'endomembrane system','C','A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.','2013-10-27','NSRP'),(9043,12506,'vesicle membrane','C','The lipid bilayer surrounding any membrane-bounded vesicle in the cell.','2013-10-27','NSRP'),(9044,12507,'ER to Golgi transport vesicle membrane','C','The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.','2013-10-27','NSRP'),(9045,12508,'Golgi to ER transport vesicle membrane','C','The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.','2013-10-27','NSRP'),(9046,12509,'inter-Golgi transport vesicle membrane','C','The lipid bilayer surrounding a vesicle transporting substances within the Golgi.','2013-10-27','NSRP'),(9047,12510,'trans-Golgi network transport vesicle membrane','C','The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.','2013-10-27','NSRP'),(9048,12511,'monolayer-surrounded lipid storage body','C','A subcellular organelle of plant cells surrounded by \'half-unit\' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.','2013-10-27','NSRP'),(9049,14001,'sclerenchyma cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.','2013-10-27','NSRP'),(9050,14002,'astrocyte development','P','The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.','2013-10-27','NSRP'),(9051,14003,'oligodendrocyte development','P','The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.','2013-10-27','NSRP'),(9052,14004,'microglia differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.','2013-10-27','NSRP'),(9053,14005,'microglia development','P','The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(9054,14006,'regulation of microglia differentiation','P','Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.','2013-10-27','NSRP'),(9055,14007,'negative regulation of microglia differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.','2013-10-27','NSRP'),(9056,14008,'positive regulation of microglia differentiation','P','Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.','2013-10-27','NSRP'),(9057,14009,'glial cell proliferation','P','The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.','2013-10-27','NSRP'),(9058,14010,'Schwann cell proliferation','P','The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.','2013-10-27','NSRP'),(9059,14011,'Schwann cell proliferation involved in axon regeneration','P','The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.','2013-10-27','NSRP'),(9060,14012,'peripheral nervous system axon regeneration','P','The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.','2013-10-27','NSRP'),(9061,14013,'regulation of gliogenesis','P','Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.','2013-10-27','NSRP'),(9062,14014,'negative regulation of gliogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.','2013-10-27','NSRP'),(9063,14015,'positive regulation of gliogenesis','P','Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.','2013-10-27','NSRP'),(9064,14016,'neuroblast differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.','2013-10-27','NSRP'),(9065,14017,'neuroblast fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.','2013-10-27','NSRP'),(9066,14018,'neuroblast fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(9067,14019,'neuroblast development','P','The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.','2013-10-27','NSRP'),(9068,14020,'primary neural tube formation','P','The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.','2013-10-27','NSRP'),(9069,14021,'secondary neural tube formation','P','The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.','2013-10-27','NSRP'),(9070,14022,'neural plate elongation','P','The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.','2013-10-27','NSRP'),(9071,14023,'neural rod formation','P','The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.','2013-10-27','NSRP'),(9072,14024,'neural rod cavitation','P','The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube.','2013-10-27','NSRP'),(9073,14025,'neural keel formation','P','The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.','2013-10-27','NSRP'),(9074,14027,'secondary neural tube rod cavitation','P','The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube.','2013-10-27','NSRP'),(9075,14028,'notochord formation','P','The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.','2013-10-27','NSRP'),(9076,14029,'neural crest formation','P','The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.','2013-10-27','NSRP'),(9077,14030,'mesenchymal cell fate commitment','P','The process in which a cell becomes committed to become a mesenchymal cell.','2013-10-27','NSRP'),(9078,14031,'mesenchymal cell development','P','The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(9079,14032,'neural crest cell development','P','The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(9080,14033,'neural crest cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.','2013-10-27','NSRP'),(9081,14034,'neural crest cell fate commitment','P','The process in which a cell becomes committed to become a neural crest cell.','2013-10-27','NSRP'),(9082,14035,'neural crest cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(9083,14036,'neural crest cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(9084,14037,'Schwann cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.','2013-10-27','NSRP'),(9085,14038,'regulation of Schwann cell differentiation','P','Any process that modulates the frequency, rate or extent of Schwann cell differentiation.','2013-10-27','NSRP'),(9086,14039,'negative regulation of Schwann cell differentiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.','2013-10-27','NSRP'),(9087,14040,'positive regulation of Schwann cell differentiation','P','Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.','2013-10-27','NSRP'),(9088,14041,'regulation of neuron maturation','P','Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.','2013-10-27','NSRP'),(9089,14042,'positive regulation of neuron maturation','P','Any process that activates or increases the frequency, rate or extent of neuron maturation.','2013-10-27','NSRP'),(9090,14043,'negative regulation of neuron maturation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.','2013-10-27','NSRP'),(9091,14044,'Schwann cell development','P','The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.','2013-10-27','NSRP'),(9092,14045,'establishment of endothelial blood-brain barrier','P','Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.','2013-10-27','NSRP'),(9093,14046,'dopamine secretion','P','The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.','2013-10-27','NSRP'),(9094,14047,'glutamate secretion','P','The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.','2013-10-27','NSRP'),(9095,14048,'regulation of glutamate secretion','P','Any process that modulates the frequency, rate or extent of the controlled release of glutamate.','2013-10-27','NSRP'),(9096,14049,'positive regulation of glutamate secretion','P','Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.','2013-10-27','NSRP'),(9097,14050,'negative regulation of glutamate secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.','2013-10-27','NSRP'),(9098,14051,'gamma-aminobutyric acid secretion','P','The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.','2013-10-27','NSRP'),(9099,14052,'regulation of gamma-aminobutyric acid secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.','2013-10-27','NSRP'),(9100,14053,'negative regulation of gamma-aminobutyric acid secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.','2013-10-27','NSRP'),(9101,14054,'positive regulation of gamma-aminobutyric acid secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.','2013-10-27','NSRP'),(9102,14055,'acetylcholine secretion, neurotransmission','P','The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).','2013-10-27','NSRP'),(9103,14056,'regulation of acetylcholine secretion, neurotransmission','P','Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.','2013-10-27','NSRP'),(9104,14057,'positive regulation of acetylcholine secretion, neurotransmission','P','Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.','2013-10-27','NSRP'),(9105,14058,'negative regulation of acetylcholine secretion, neurotransmission','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.','2013-10-27','NSRP'),(9106,14059,'regulation of dopamine secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of dopamine.','2013-10-27','NSRP'),(9107,14060,'regulation of epinephrine secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.','2013-10-27','NSRP'),(9108,14061,'regulation of norepinephrine secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.','2013-10-27','NSRP'),(9109,14062,'regulation of serotonin secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of serotonin.','2013-10-27','NSRP'),(9110,14063,'negative regulation of serotonin secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.','2013-10-27','NSRP'),(9111,14064,'positive regulation of serotonin secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.','2013-10-27','NSRP'),(9112,14065,'phosphatidylinositol 3-kinase cascade','P','A series of reactions, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). PI3K cascades lie downstream of many cell surface receptor linked signaling pathways and regulate numerous cellular functions.','2013-10-27','NSRP'),(9113,14066,'regulation of phosphatidylinositol 3-kinase cascade','P','Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.','2013-10-27','NSRP'),(9114,14067,'negative regulation of phosphatidylinositol 3-kinase cascade','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.','2013-10-27','NSRP'),(9115,14068,'positive regulation of phosphatidylinositol 3-kinase cascade','P','Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.','2013-10-27','NSRP'),(9116,14069,'postsynaptic density','C','The postsynaptic density is a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse. It forms a disc that consists of a range of proteins with different functions, some of which contact the cytoplasmic domains of ion channels in the postsynaptic membrane. The proteins making up the disc include receptors, and structural proteins linked to the actin cytoskeleton. They also include signalling machinery, such as protein kinases and phosphatases. The postsynaptic density may be part of a neuron or a muscle cell or a glial cell.','2013-10-27','NSRP'),(9117,14070,'response to organic cyclic compound','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.','2013-10-27','NSRP'),(9118,14071,'response to cycloalkane','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.','2013-10-27','NSRP'),(9119,14072,'response to isoquinoline alkaloid','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.','2013-10-27','NSRP'),(9120,14073,'response to tropane','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.','2013-10-27','NSRP'),(9121,14074,'response to purine-containing compound','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.','2013-10-27','NSRP'),(9122,14075,'response to amine stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.','2013-10-27','NSRP'),(9123,14076,'response to fluoxetine','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.','2013-10-27','NSRP'),(9124,14701,'junctional sarcoplasmic reticulum membrane','C','The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.','2013-10-27','NSRP'),(9125,14702,'free sarcoplasmic reticulum membrane','C','The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.','2013-10-27','NSRP'),(9126,14703,'oscillatory muscle contraction','P','A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.','2013-10-27','NSRP'),(9127,14704,'intercalated disc','C','A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.','2013-10-27','NSRP'),(9128,14705,'C zone','C','A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.','2013-10-27','NSRP'),(9129,14706,'striated muscle tissue development','P','The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.','2013-10-27','NSRP'),(9130,14707,'branchiomeric skeletal muscle development','P','The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.','2013-10-27','NSRP'),(9131,14708,'regulation of somitomeric trunk muscle development','P','Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.','2013-10-27','NSRP'),(9132,14709,'positive regulation of somitomeric trunk muscle development','P','Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.','2013-10-27','NSRP'),(9133,14710,'negative regulation of somitomeric trunk muscle development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.','2013-10-27','NSRP'),(9134,14711,'regulation of branchiomeric skeletal muscle development','P','Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.','2013-10-27','NSRP'),(9135,14712,'positive regulation of branchiomeric skeletal muscle development','P','Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.','2013-10-27','NSRP'),(9136,14713,'negative regulation of branchiomeric skeletal muscle development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.','2013-10-27','NSRP'),(9137,14714,'myoblast fate commitment in head','P','The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9138,14715,'myoblast fate commitment in trunk','P','The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9139,14716,'satellite cell asymmetric division involved in skeletal muscle regeneration','P','Satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9140,14717,'regulation of satellite cell activation involved in skeletal muscle regeneration','P','Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.','2013-10-27','NSRP'),(9141,14718,'positive regulation of satellite cell activation involved in skeletal muscle regeneration','P','Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.','2013-10-27','NSRP'),(9142,14719,'satellite cell activation','P','A change in the morphology or behavior of a satellite cell resulting from exposure to an activating factor such as a cellular or soluble ligand. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9143,14720,'tonic skeletal muscle contraction','P','A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.','2013-10-27','NSRP'),(9144,14721,'twitch skeletal muscle contraction','P','A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.','2013-10-27','NSRP'),(9145,14722,'regulation of skeletal muscle contraction by calcium ion signaling','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.','2013-10-27','NSRP'),(9146,14723,'regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.','2013-10-27','NSRP'),(9147,14724,'regulation of twitch skeletal muscle contraction','P','Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.','2013-10-27','NSRP'),(9148,14725,'regulation of extraocular skeletal muscle development','P','Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.','2013-10-27','NSRP'),(9149,14726,'negative regulation of extraocular skeletal muscle development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.','2013-10-27','NSRP'),(9150,14727,'positive regulation of extraocular skeletal muscle development','P','Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.','2013-10-27','NSRP'),(9151,14728,'regulation of the force of skeletal muscle contraction','P','Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.','2013-10-27','NSRP'),(9152,14729,'regulation of the velocity of shortening of skeletal muscle modulating contraction','P','Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.','2013-10-27','NSRP'),(9153,14730,'skeletal muscle regeneration at neuromuscular junction','P','The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.','2013-10-27','NSRP'),(9154,14731,'spectrin-associated cytoskeleton','C','The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.','2013-10-27','NSRP'),(9155,14732,'skeletal muscle atrophy','P','A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.','2013-10-27','NSRP'),(9156,14733,'regulation of skeletal muscle adaptation','P','Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.','2013-10-27','NSRP'),(9157,14734,'skeletal muscle hypertrophy','P','The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.','2013-10-27','NSRP'),(9158,14735,'regulation of muscle atrophy','P','Any process that modulates the frequency, rate or extent of muscle atrophy.','2013-10-27','NSRP'),(9159,14736,'negative regulation of muscle atrophy','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.','2013-10-27','NSRP'),(9160,14737,'positive regulation of muscle atrophy','P','Any process that activates or increases the frequency, rate or extent of muscle atrophy.','2013-10-27','NSRP'),(9161,14738,'regulation of muscle hyperplasia','P','Any process that modulates the frequency, rate or extent of muscle hyperplasia.','2013-10-27','NSRP'),(9162,14739,'positive regulation of muscle hyperplasia','P','Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.','2013-10-27','NSRP'),(9163,14740,'negative regulation of muscle hyperplasia','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.','2013-10-27','NSRP'),(9164,14741,'negative regulation of muscle hypertrophy','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.','2013-10-27','NSRP'),(9165,14742,'positive regulation of muscle hypertrophy','P','Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.','2013-10-27','NSRP'),(9166,14743,'regulation of muscle hypertrophy','P','Any process that modulates the frequency, rate or extent of muscle hypertrophy.','2013-10-27','NSRP'),(9167,14744,'positive regulation of muscle adaptation','P','Any process that activates or increases the frequency, rate or extent of muscle adaptation.','2013-10-27','NSRP'),(9168,14745,'negative regulation of muscle adaptation','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.','2013-10-27','NSRP'),(9169,14746,'regulation of tonic skeletal muscle contraction','P','Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.','2013-10-27','NSRP'),(9170,14747,'positive regulation of tonic skeletal muscle contraction','P','Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.','2013-10-27','NSRP'),(9171,14748,'negative regulation of tonic skeletal muscle contraction','P','Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.','2013-10-27','NSRP'),(9172,14801,'longitudinal sarcoplasmic reticulum','C','The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.','2013-10-27','NSRP'),(9173,14802,'terminal cisterna','C','The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.','2013-10-27','NSRP'),(9174,14803,'longitudinal sarcoplasmic reticulum lumen','C','The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.','2013-10-27','NSRP'),(9175,14804,'terminal cisterna lumen','C','The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.','2013-10-27','NSRP'),(9176,14805,'smooth muscle adaptation','P','Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.','2013-10-27','NSRP'),(9177,14806,'smooth muscle hyperplasia','P','A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.','2013-10-27','NSRP'),(9178,14807,'regulation of somitogenesis','P','Any process that modulates the frequency, rate or extent of somitogenesis.','2013-10-27','NSRP'),(9179,14808,'release of sequestered calcium ion into cytosol by sarcoplasmic reticulum','P','The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.','2013-10-27','NSRP'),(9180,14809,'regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.','2013-10-27','NSRP'),(9181,14810,'positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion','P','Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.','2013-10-27','NSRP'),(9182,14811,'negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.','2013-10-27','NSRP'),(9183,14812,'muscle cell migration','P','The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.','2013-10-27','NSRP'),(9184,14813,'satellite cell commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.','2013-10-27','NSRP'),(9185,14814,'axon regeneration at neuromuscular junction','P','The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.','2013-10-27','NSRP'),(9186,14815,'initiation of satellite cell activation by growth factor signalling, involved in skeletal muscle regeneration','P','Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9187,14816,'satellite cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.','2013-10-27','NSRP'),(9188,14817,'satellite cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(9189,14818,'satellite cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(9190,14819,'regulation of skeletal muscle contraction','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction.','2013-10-27','NSRP'),(9191,14820,'tonic smooth muscle contraction','P','A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.','2013-10-27','NSRP'),(9192,14821,'phasic smooth muscle contraction','P','A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.','2013-10-27','NSRP'),(9193,14822,'detection of wounding','P','The series of events by which an injury stimulus is received and converted into a molecular signal.','2013-10-27','NSRP'),(9194,14823,'response to activity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.','2013-10-27','NSRP'),(9195,14824,'artery smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.','2013-10-27','NSRP'),(9196,14825,'stomach fundus smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.','2013-10-27','NSRP'),(9197,14826,'vein smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.','2013-10-27','NSRP'),(9198,14827,'intestine smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.','2013-10-27','NSRP'),(9199,14828,'distal stomach smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.','2013-10-27','NSRP'),(9200,14829,'vascular smooth muscle contraction','P','A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.','2013-10-27','NSRP'),(9201,14830,'arteriole smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.','2013-10-27','NSRP'),(9202,14831,'gastro-intestinal system smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).','2013-10-27','NSRP'),(9203,14832,'urinary bladder smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.','2013-10-27','NSRP'),(9204,14833,'satellite cell asymmetric division','P','The asymmetric division of a satellite cell that occurs when a satellite cell divides to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool. Satellite cells are quiescent adult muscle stem cells that become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9205,14834,'satellite cell maintenance involved in skeletal muscle regeneration','P','The process essential to maintain a ready source of satellite cells. It consists of the return of activated satellite cells to a quiescent state after proliferation to replenish the satellite cell pool. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9206,14835,'myoblast differentiation involved in skeletal muscle regeneration','P','The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9207,14836,'myoblast fate commitment involved in skeletal muscle regeneration','P','The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9208,14837,'myoblast fate determination involved in skeletal muscle regeneration','P','The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9209,14838,'myoblast fate specification involved in skeletal muscle regeneration','P','The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9210,14839,'myoblast migration involved in skeletal muscle regeneration','P','The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9211,14841,'satellite cell proliferation','P','The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9212,14842,'regulation of satellite cell proliferation','P','Any process that modulates the frequency, rate or extent of satellite cell proliferation.','2013-10-27','NSRP'),(9213,14843,'growth factor dependent regulation of satellite cell proliferation','P','Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.','2013-10-27','NSRP'),(9214,14844,'myoblast proliferation involved in skeletal muscle regeneration','P','The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9215,14845,'stomach body smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.','2013-10-27','NSRP'),(9216,14846,'esophagus smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.','2013-10-27','NSRP'),(9217,14847,'proximal stomach smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.','2013-10-27','NSRP'),(9218,14848,'urinary tract smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.','2013-10-27','NSRP'),(9219,14849,'ureter smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.','2013-10-27','NSRP'),(9220,14850,'response to muscle activity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.','2013-10-27','NSRP'),(9221,14852,'regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.','2013-10-27','NSRP'),(9222,14853,'regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction','P','Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.','2013-10-27','NSRP'),(9223,14854,'response to inactivity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.','2013-10-27','NSRP'),(9224,14855,'striated muscle cell proliferation','P','The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.','2013-10-27','NSRP'),(9225,14856,'skeletal muscle cell proliferation','P','The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.','2013-10-27','NSRP'),(9226,14857,'regulation of skeletal muscle cell proliferation','P','Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.','2013-10-27','NSRP'),(9227,14858,'positive regulation of skeletal muscle cell proliferation','P','Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.','2013-10-27','NSRP'),(9228,14859,'negative regulation of skeletal muscle cell proliferation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.','2013-10-27','NSRP'),(9229,14860,'neurotransmitter secretion involved in regulation of skeletal muscle contraction','P','The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.','2013-10-27','NSRP'),(9230,14861,'regulation of skeletal muscle contraction via regulation of action potential','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.','2013-10-27','NSRP'),(9231,14862,'regulation of skeletal muscle contraction by chemo-mechanical energy conversion','P','Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.','2013-10-27','NSRP'),(9232,14863,'detection of inactivity','P','The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.','2013-10-27','NSRP'),(9233,14864,'detection of muscle activity','P','The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(9234,14865,'detection of activity','P','The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(9235,14866,'skeletal myofibril assembly','P','The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.','2013-10-27','NSRP'),(9236,14868,'cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction','P','A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.','2013-10-27','NSRP'),(9237,14869,'detection of muscle inactivity','P','The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(9238,14870,'response to muscle inactivity','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.','2013-10-27','NSRP'),(9239,14871,'cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction','P','The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.','2013-10-27','NSRP'),(9240,14872,'myoblast division','P','The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9241,14873,'response to muscle activity involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9242,14874,'response to stimulus involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9243,14875,'detection of muscle activity involved in regulation of muscle adaptation','P','The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9244,14876,'response to injury involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9245,14877,'response to muscle inactivity involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9246,14878,'response to electrical stimulus involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9247,14879,'detection of electrical stimulus involved in regulation of muscle adaptation','P','The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9248,14880,'regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction','P','Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.','2013-10-27','NSRP'),(9249,14881,'regulation of myofibril size','P','Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.','2013-10-27','NSRP'),(9250,14882,'regulation of myofibril number','P','Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.','2013-10-27','NSRP'),(9251,14883,'transition between fast and slow fiber','P','The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.','2013-10-27','NSRP'),(9252,14884,'detection of muscle inactivity involved in regulation of muscle adaptation','P','The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9253,14885,'detection of injury involved in regulation of muscle adaptation','P','The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9254,14886,'transition between slow and fast fiber','P','The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.','2013-10-27','NSRP'),(9255,14887,'cardiac muscle adaptation','P','The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.','2013-10-27','NSRP'),(9256,14888,'striated muscle adaptation','P','Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.','2013-10-27','NSRP'),(9257,14889,'muscle atrophy','P','A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.','2013-10-27','NSRP'),(9258,14890,'smooth muscle atrophy','P','A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.','2013-10-27','NSRP'),(9259,14891,'striated muscle atrophy','P','A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.','2013-10-27','NSRP'),(9260,14893,'response to rest involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9261,14894,'response to denervation involved in regulation of muscle adaptation','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.','2013-10-27','NSRP'),(9262,14895,'smooth muscle hypertrophy','P','The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.','2013-10-27','NSRP'),(9263,14896,'muscle hypertrophy','P','The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.','2013-10-27','NSRP'),(9264,14897,'striated muscle hypertrophy','P','The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.','2013-10-27','NSRP'),(9265,14898,'cardiac muscle hypertrophy in response to stress','P','The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.','2013-10-27','NSRP'),(9266,14899,'cardiac muscle atrophy','P','A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.','2013-10-27','NSRP'),(9267,14900,'muscle hyperplasia','P','A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.','2013-10-27','NSRP'),(9268,14901,'satellite cell activation involved in skeletal muscle regeneration','P','The process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.','2013-10-27','NSRP'),(9269,14902,'myotube differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(9270,14904,'myotube cell development','P','The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(9271,14905,'myoblast fusion involved in skeletal muscle regeneration','P','A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9272,14906,'myotube cell development involved in skeletal muscle regeneration','P','The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(9273,14908,'myotube differentiation involved in skeletal muscle regeneration','P','The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.','2013-10-27','NSRP'),(9274,14909,'smooth muscle cell migration','P','The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.','2013-10-27','NSRP'),(9275,14910,'regulation of smooth muscle cell migration','P','Any process that modulates the frequency, rate or extent of smooth muscle cell migration.','2013-10-27','NSRP'),(9276,14911,'positive regulation of smooth muscle cell migration','P','Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.','2013-10-27','NSRP'),(9277,14912,'negative regulation of smooth muscle cell migration','P','Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.','2013-10-27','NSRP'),(9278,14914,'myoblast maturation involved in muscle regeneration','P','A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.','2013-10-27','NSRP'),(9279,14915,'regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction','P','Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.','2013-10-27','NSRP'),(9280,14916,'regulation of lung blood pressure','P','The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.','2013-10-27','NSRP'),(9281,14917,'positive regulation of diuresis by pressure natriuresis','P','OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis.','2013-10-27','NSRP'),(9282,14918,'positive regulation of natriuresis by pressure natriuresis','P','OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis.','2013-10-27','NSRP'),(9283,15000,'polyferredoxin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9284,15001,'high-potential iron-sulfur carrier','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9285,15002,'heme-copper terminal oxidase activity','F','Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.','2013-10-27','NSRP'),(9286,15003,'copper electron carrier','F','OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system.','2013-10-27','NSRP'),(9287,15004,'small blue copper electron carrier','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9288,15005,'azurin','F','OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin.','2013-10-27','NSRP'),(9289,15006,'plastocyanin','F','OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I.','2013-10-27','NSRP'),(9290,15007,'electron carrier, chlorophyll electron transport system','F','OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system.','2013-10-27','NSRP'),(9291,15009,'corrin metabolic process','P','The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.','2013-10-27','NSRP'),(9292,15010,'tetrahydrocorphin metabolic process','P','The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.','2013-10-27','NSRP'),(9293,15011,'nickel-tetrapyrrole coenzyme metabolic process','P','The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.','2013-10-27','NSRP'),(9294,15012,'heparan sulfate proteoglycan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.','2013-10-27','NSRP'),(9295,15013,'heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide','P','The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.','2013-10-27','NSRP'),(9296,15014,'heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process','P','The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.','2013-10-27','NSRP'),(9297,15015,'heparan sulfate proteoglycan biosynthetic process, enzymatic modification','P','The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.','2013-10-27','NSRP'),(9298,15016,'[heparan sulfate]-glucosamine N-sulfotransferase activity','F','Catalysis of the reaction: 3\'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3\',5\'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.','2013-10-27','NSRP'),(9299,15017,'glypican','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9300,15018,'galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity','F','Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.','2013-10-27','NSRP'),(9301,15019,'heparan-alpha-glucosaminide N-acetyltransferase activity','F','Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.','2013-10-27','NSRP'),(9302,15020,'glucuronosyltransferase activity','F','Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.','2013-10-27','NSRP'),(9303,15021,'heparin-sulfate lyase activity','F','Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.','2013-10-27','NSRP'),(9304,15023,'syndecan','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9305,15024,'glucuronate-2-sulfatase activity','F','Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.','2013-10-27','NSRP'),(9306,15025,'GPI-anchored membrane-bound receptor','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9307,15026,'coreceptor activity','F','Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.','2013-10-27','NSRP'),(9308,15029,'internalization receptor activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9309,15030,'Cajal body','C','A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.','2013-10-27','NSRP'),(9310,15031,'protein transport','P','The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9311,15032,'storage protein import into fat body','P','The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.','2013-10-27','NSRP'),(9312,15034,'cytochrome P450 activity','F','OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer.','2013-10-27','NSRP'),(9313,15035,'protein disulfide oxidoreductase activity','F','Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.','2013-10-27','NSRP'),(9314,15036,'disulfide oxidoreductase activity','F','Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.','2013-10-27','NSRP'),(9315,15037,'peptide disulfide oxidoreductase activity','F','Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds.','2013-10-27','NSRP'),(9316,15038,'glutathione disulfide oxidoreductase activity','F','Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.','2013-10-27','NSRP'),(9317,15039,'NADPH-adrenodoxin reductase activity','F','Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.','2013-10-27','NSRP'),(9318,15040,'electron transfer flavoprotein, group I','F','OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.','2013-10-27','NSRP'),(9319,15041,'electron transfer flavoprotein, group II','F','OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation.','2013-10-27','NSRP'),(9320,15042,'trypanothione-disulfide reductase activity','F','Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.','2013-10-27','NSRP'),(9321,15043,'leghemoglobin reductase activity','F','Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin.','2013-10-27','NSRP'),(9322,15044,'rubredoxin-NAD+ reductase activity','F','Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.','2013-10-27','NSRP'),(9323,15045,'rubredoxin-NAD(P)+ reductase activity','F','Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.','2013-10-27','NSRP'),(9324,15046,'rubredoxin-NADP reductase activity','F','Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.','2013-10-27','NSRP'),(9325,15047,'NADPH-cytochrome-c2 reductase activity','F','Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.','2013-10-27','NSRP'),(9326,15048,'phthalate dioxygenase reductase activity','F','Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.','2013-10-27','NSRP'),(9327,15049,'methane monooxygenase activity','F','Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.','2013-10-27','NSRP'),(9328,15050,'methane monooxygenase complex','C','A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.','2013-10-27','NSRP'),(9329,15051,'X-opioid receptor activity','F','OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.','2013-10-27','NSRP'),(9330,15052,'beta3-adrenergic receptor activity','F','Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.','2013-10-27','NSRP'),(9331,15053,'opsin','F','OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin.','2013-10-27','NSRP'),(9332,15054,'gastrin receptor activity','F','Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.','2013-10-27','NSRP'),(9333,15055,'secretin receptor activity','F','Combining with secretin to initiate a change in cell activity.','2013-10-27','NSRP'),(9334,15056,'corticotrophin-releasing factor receptor activity','F','Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.','2013-10-27','NSRP'),(9335,15057,'thrombin receptor activity','F','Combining with thrombin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.','2013-10-27','NSRP'),(9336,15058,'epidermal growth factor-like module containing hormone receptor activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9337,15059,'blue-sensitive opsin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9338,15060,'green-sensitive opsin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9339,15061,'red-sensitive opsin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9340,15062,'violet-sensitive opsin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9341,15063,'long-wave-sensitive opsin','F','OBSOLETE. An opsin with maximal absorption above 500 nm.','2013-10-27','NSRP'),(9342,15064,'UV-sensitive opsin','F','OBSOLETE. An opsin with maximal absorption below 400 nm.','2013-10-27','NSRP'),(9343,15065,'uridine nucleotide receptor activity','F','Combining with UTP or UDP to initiate a change in cell activity.','2013-10-27','NSRP'),(9344,15066,'alpha-amylase inhibitor activity','F','Stops, prevents or reduces the activity of alpha-amylase.','2013-10-27','NSRP'),(9345,15067,'amidinotransferase activity','F','Catalysis of the reversible transfer of an amidino group to an acceptor.','2013-10-27','NSRP'),(9346,15068,'glycine amidinotransferase activity','F','Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.','2013-10-27','NSRP'),(9347,15069,'scyllo-inosamine-4-phosphate amidinotransferase activity','F','Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.','2013-10-27','NSRP'),(9348,15070,'toxin activity','F','OBSOLETE. Acts as to cause injury to other living organisms.','2013-10-27','NSRP'),(9349,15072,'phosphatidylinositol 3-kinase, class I, catalyst activity','F','OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.','2013-10-27','NSRP'),(9350,15073,'phosphatidylinositol 3-kinase, class I, regulator activity','F','OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.','2013-10-27','NSRP'),(9351,15074,'DNA integration','P','The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome.','2013-10-27','NSRP'),(9352,15075,'ion transmembrane transporter activity','F','Catalysis of the transfer of an ion from one side of a membrane to the other.','2013-10-27','NSRP'),(9353,15076,'heavy metal ion transporter activity','F','OBSOLETE. Enables the directed movement of heavy metal ions into, out of or within a cell, or between cells. Heavy metals are those that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.','2013-10-27','NSRP'),(9354,15077,'monovalent inorganic cation transmembrane transporter activity','F','Catalysis of the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.','2013-10-27','NSRP'),(9355,15078,'hydrogen ion transmembrane transporter activity','F','Catalysis of the transfer of hydrogen ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9356,15079,'potassium ion transmembrane transporter activity','F','Catalysis of the transfer of potassium ions (K+) from one side of a membrane to the other.','2013-10-27','NSRP'),(9357,15080,'silver ion transmembrane transporter activity','F','Catalysis of the transfer of silver (Ag) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9358,15081,'sodium ion transmembrane transporter activity','F','Catalysis of the transfer of sodium ions (Na+) from one side of a membrane to the other.','2013-10-27','NSRP'),(9359,15083,'aluminum ion transmembrane transporter activity','F','Catalysis of the transfer of aluminum (Al) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9360,15085,'calcium ion transmembrane transporter activity','F','Catalysis of the transfer of calcium (Ca) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9361,15086,'cadmium ion transmembrane transporter activity','F','Catalysis of the transfer of cadmium (Cd) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9362,15087,'cobalt ion transmembrane transporter activity','F','Catalysis of the transfer of cobalt (Co) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9363,15088,'copper uptake transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu+(out) = Cu+(in).','2013-10-27','NSRP'),(9364,15089,'high affinity copper ion transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu2+(out) = Cu2+(in).','2013-10-27','NSRP'),(9365,15090,'low affinity iron ion transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in).','2013-10-27','NSRP'),(9366,15091,'ferric iron transmembrane transporter activity','F','Catalysis of the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9367,15092,'high affinity ferric uptake transmembrane transporter activity','F','Catalysis of the transfer of Fe(III) from the outside of a cell to the inside of a cell across a membrane.','2013-10-27','NSRP'),(9368,15093,'ferrous iron transmembrane transporter activity','F','Catalysis of the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9369,15094,'lead ion transmembrane transporter activity','F','Catalysis of the transfer of lead (Pb) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9370,15095,'magnesium ion transmembrane transporter activity','F','Catalysis of the transfer of magnesium (Mg) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9371,15096,'manganese resistance permease activity','F','OBSOLETE.','2013-10-27','NSRP'),(9372,15097,'mercury ion transmembrane transporter activity','F','Catalysis of the transfer of mercury (Hg) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9373,15098,'molybdate ion transmembrane transporter activity','F','Catalysis of the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.','2013-10-27','NSRP'),(9374,15099,'nickel cation transmembrane transporter activity','F','Catalysis of the transfer of nickel (Ni) cations from one side of a membrane to the other.','2013-10-27','NSRP'),(9375,15100,'vanadium ion transmembrane transporter activity','F','Catalysis of the transfer of vanadium (V) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9376,15101,'organic cation transmembrane transporter activity','F','Catalysis of the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.','2013-10-27','NSRP'),(9377,15103,'inorganic anion transmembrane transporter activity','F','Catalysis of the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.','2013-10-27','NSRP'),(9378,15104,'antimonite transmembrane transporter activity','F','Catalysis of the transfer of antimonite from one side of a membrane to the other.','2013-10-27','NSRP'),(9379,15105,'arsenite transmembrane transporter activity','F','Catalysis of the transfer of arsenite from one side of a membrane to the other.','2013-10-27','NSRP'),(9380,15106,'bicarbonate transmembrane transporter activity','F','Catalysis of the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.','2013-10-27','NSRP'),(9381,15107,'chlorate transmembrane transporter activity','F','Catalysis of the transfer of chlorate, ClO3-, from one side of a membrane to the other.','2013-10-27','NSRP'),(9382,15108,'chloride transmembrane transporter activity','F','Catalysis of the transfer of chloride ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9383,15109,'chromate transmembrane transporter activity','F','Catalysis of the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.','2013-10-27','NSRP'),(9384,15110,'cyanate transmembrane transporter activity','F','Catalysis of the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.','2013-10-27','NSRP'),(9385,15111,'iodide transmembrane transporter activity','F','Catalysis of the transfer of iodide ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9386,15112,'nitrate transmembrane transporter activity','F','Catalysis of the transfer of nitrate ions (NO3-) from one side of a membrane to the other.','2013-10-27','NSRP'),(9387,15113,'nitrite transmembrane transporter activity','F','Catalysis of the transfer of nitrite (NO2-) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9388,15114,'phosphate ion transmembrane transporter activity','F','Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(9389,15115,'silicate transmembrane transporter activity','F','Catalysis of the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.','2013-10-27','NSRP'),(9390,15116,'sulfate transmembrane transporter activity','F','Catalysis of the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.','2013-10-27','NSRP'),(9391,15117,'thiosulfate transmembrane transporter activity','F','Catalysis of the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.','2013-10-27','NSRP'),(9392,15118,'tellurite transmembrane transporter activity','F','Catalysis of the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.','2013-10-27','NSRP'),(9393,15119,'hexose phosphate transmembrane transporter activity','F','Catalysis of the transfer of hexose phosphate from one side of the membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.','2013-10-27','NSRP'),(9394,15120,'phosphoglycerate transmembrane transporter activity','F','Catalysis of the transfer of phosphoglycerates from one side of the membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.','2013-10-27','NSRP'),(9395,15121,'phosphoenolpyruvate:phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).','2013-10-27','NSRP'),(9396,15123,'acetate transmembrane transporter activity','F','Catalysis of the transfer of acetate from one side of the membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.','2013-10-27','NSRP'),(9397,15124,'allantoate transmembrane transporter activity','F','Catalysis of the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.','2013-10-27','NSRP'),(9398,15125,'bile acid transmembrane transporter activity','F','Catalysis of the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.','2013-10-27','NSRP'),(9399,15126,'canalicular bile acid transmembrane transporter activity','F','The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.','2013-10-27','NSRP'),(9400,15127,'bilirubin transmembrane transporter activity','F','Catalysis of the transfer of bilirubin from one side of the membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.','2013-10-27','NSRP'),(9401,15128,'gluconate transmembrane transporter activity','F','Catalysis of the transfer of gluconate from one side of the membrane to the other. Gluconate is the aldonic acid derived from glucose.','2013-10-27','NSRP'),(9402,15129,'lactate transmembrane transporter activity','F','Catalysis of the transfer of lactate from one side of the membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.','2013-10-27','NSRP'),(9403,15130,'mevalonate transmembrane transporter activity','F','Catalysis of the transfer of mevalonate from one side of the membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.','2013-10-27','NSRP'),(9404,15131,'oxaloacetate transmembrane transporter activity','F','Catalysis of the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of the membrane to the other.','2013-10-27','NSRP'),(9405,15132,'prostaglandin transmembrane transporter activity','F','Catalysis of the transfer of prostaglandins from one side of the membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.','2013-10-27','NSRP'),(9406,15133,'uronic acid transmembrane transporter activity','F','Catalysis of the transfer of uronic acid from one side of the membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.','2013-10-27','NSRP'),(9407,15134,'hexuronate transmembrane transporter activity','F','Catalysis of the transfer of hexuronates from one side of the membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.','2013-10-27','NSRP'),(9408,15135,'glucuronate transmembrane transporter activity','F','Catalysis of the transfer of glucuronate from one side of the membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.','2013-10-27','NSRP'),(9409,15136,'sialic acid transmembrane transporter activity','F','Catalysis of the transfer of sialic acid from one side of the membrane to the other.','2013-10-27','NSRP'),(9410,15137,'citrate transmembrane transporter activity','F','Catalysis of the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of the membrane to the other.','2013-10-27','NSRP'),(9411,15138,'fumarate transmembrane transporter activity','F','Catalysis of the transfer of fumarate from one side of the membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.','2013-10-27','NSRP'),(9412,15139,'alpha-ketoglutarate transmembrane transporter activity','F','Catalysis of the transfer of alpha-ketoglutarate from one side of the membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.','2013-10-27','NSRP'),(9413,15140,'malate transmembrane transporter activity','F','Catalysis of the transfer of malate from one side of the membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.','2013-10-27','NSRP'),(9414,15141,'succinate transmembrane transporter activity','F','Catalysis of the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of the membrane to the other.','2013-10-27','NSRP'),(9415,15142,'tricarboxylic acid transmembrane transporter activity','F','Catalysis of the transfer of tricarboxylic acids from one side of the membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.','2013-10-27','NSRP'),(9416,15143,'urate transmembrane transporter activity','F','Catalysis of the transfer of urate from one side of the membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.','2013-10-27','NSRP'),(9417,15144,'carbohydrate transmembrane transporter activity','F','Catalysis of the transfer of carbohydrate from one side of the membrane to the other.','2013-10-27','NSRP'),(9418,15145,'monosaccharide transmembrane transporter activity','F','Catalysis of the transfer of a monosaccharide from one side of a membrane to the other.','2013-10-27','NSRP'),(9419,15146,'pentose transmembrane transporter activity','F','Catalysis of the transfer of a pentose sugar, a monosaccharide with 5 carbon atoms, from one side of the membrane to the other.','2013-10-27','NSRP'),(9420,15147,'L-arabinose transmembrane transporter activity','F','Catalysis of the transfer of L-arabinose from one side of the membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.','2013-10-27','NSRP'),(9421,15148,'D-xylose transmembrane transporter activity','F','Catalysis of the transfer of D-xylose from one side of the membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.','2013-10-27','NSRP'),(9422,15149,'hexose transmembrane transporter activity','F','Catalysis of the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.','2013-10-27','NSRP'),(9423,15150,'fucose transmembrane transporter activity','F','Catalysis of the transfer of fucose from one side of the membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.','2013-10-27','NSRP'),(9424,15151,'alpha-glucoside transmembrane transporter activity','F','Catalysis of the transfer of alpha-glucosides from one side of the membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.','2013-10-27','NSRP'),(9425,15152,'glucose-6-phosphate transmembrane transporter activity','F','Catalysis of the transfer of glucose-6-phosphate from one side of the membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.','2013-10-27','NSRP'),(9426,15153,'rhamnose transmembrane transporter activity','F','Catalysis of the transfer of rhamnose from one side of the membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.','2013-10-27','NSRP'),(9427,15154,'disaccharide transmembrane transporter activity','F','Catalysis of the transfer of disaccharide from one side of the membrane to the other.','2013-10-27','NSRP'),(9428,15155,'lactose transmembrane transporter activity','F','Catalysis of the transfer of lactose from one side of the membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.','2013-10-27','NSRP'),(9429,15156,'melibiose transmembrane transporter activity','F','Catalysis of the transfer of melibiose from one side of the membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.','2013-10-27','NSRP'),(9430,15157,'oligosaccharide transmembrane transporter activity','F','Catalysis of the transfer of oligosaccharide from one side of the membrane to the other.','2013-10-27','NSRP'),(9431,15158,'raffinose transmembrane transporter activity','F','Catalysis of the transfer of raffinose from one side of the membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.','2013-10-27','NSRP'),(9432,15159,'polysaccharide transmembrane transporter activity','F','Catalysis of the transfer of polysaccharides from one side of the membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.','2013-10-27','NSRP'),(9433,15160,'beta-glucan transmembrane transporter activity','F','Catalysis of the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.','2013-10-27','NSRP'),(9434,15161,'capsular polysaccharide transmembrane transporter activity','F','Catalysis of the transfer of capsular-polysaccharides from one side of the membrane to the other. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.','2013-10-27','NSRP'),(9435,15162,'teichoic acid transmembrane transporter activity','F','Catalysis of the transfer of teichoic acid from one side of the membrane to the other. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.','2013-10-27','NSRP'),(9436,15163,'hexuronide transmembrane transporter activity','F','Catalysis of the transfer of a hexuronide from one side of the membrane to the other. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.','2013-10-27','NSRP'),(9437,15164,'glucuronoside transmembrane transporter activity','F','Catalysis of the transfer of a glucuronosides from one side of the membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.','2013-10-27','NSRP'),(9438,15165,'pyrimidine nucleotide-sugar transmembrane transporter activity','F','Catalysis of the transfer of a pyrimidine nucleotide-sugar from one side of the membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.','2013-10-27','NSRP'),(9439,15166,'polyol transmembrane transporter activity','F','Catalysis of the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol.','2013-10-27','NSRP'),(9440,15167,'arabitol transmembrane transporter activity','F','Catalysis of the transfer of an arabitol from one side of the membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.','2013-10-27','NSRP'),(9441,15168,'glycerol transmembrane transporter activity','F','Catalysis of the transfer of glycerol from one side of the membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.','2013-10-27','NSRP'),(9442,15169,'glycerol-3-phosphate transmembrane transporter activity','F','Catalysis of the transfer of glycerol-3-phosphate from one side of the membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.','2013-10-27','NSRP'),(9443,15170,'propanediol transmembrane transporter activity','F','Catalysis of the transfer of propanediol from one side of the membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.','2013-10-27','NSRP'),(9444,15171,'amino acid transmembrane transporter activity','F','Catalysis of the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.','2013-10-27','NSRP'),(9445,15172,'acidic amino acid transmembrane transporter activity','F','Catalysis of the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have a pH below 7.','2013-10-27','NSRP'),(9446,15173,'aromatic amino acid transmembrane transporter activity','F','Catalysis of the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.','2013-10-27','NSRP'),(9447,15174,'basic amino acid transmembrane transporter activity','F','Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7.','2013-10-27','NSRP'),(9448,15175,'neutral amino acid transmembrane transporter activity','F','Catalysis of the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.','2013-10-27','NSRP'),(9449,15176,'holin','F','OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases.','2013-10-27','NSRP'),(9450,15179,'L-amino acid transmembrane transporter activity','F','Catalysis of the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.','2013-10-27','NSRP'),(9451,15180,'L-alanine transmembrane transporter activity','F','Catalysis of the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.','2013-10-27','NSRP'),(9452,15181,'arginine transmembrane transporter activity','F','Catalysis of the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.','2013-10-27','NSRP'),(9453,15182,'L-asparagine transmembrane transporter activity','F','Catalysis of the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.','2013-10-27','NSRP'),(9454,15183,'L-aspartate transmembrane transporter activity','F','Catalysis of the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.','2013-10-27','NSRP'),(9455,15184,'L-cystine transmembrane transporter activity','F','Catalysis of the transfer of L-cystine from one side of a membrane to the other.','2013-10-27','NSRP'),(9456,15185,'gamma-aminobutyric acid transmembrane transporter activity','F','Catalysis of the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).','2013-10-27','NSRP'),(9457,15186,'L-glutamine transmembrane transporter activity','F','Catalysis of the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.','2013-10-27','NSRP'),(9458,15187,'glycine transmembrane transporter activity','F','Catalysis of the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.','2013-10-27','NSRP'),(9459,15188,'L-isoleucine transmembrane transporter activity','F','Catalysis of the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.','2013-10-27','NSRP'),(9460,15189,'L-lysine transmembrane transporter activity','F','Catalysis of the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.','2013-10-27','NSRP'),(9461,15190,'L-leucine transmembrane transporter activity','F','Catalysis of the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.','2013-10-27','NSRP'),(9462,15191,'L-methionine transmembrane transporter activity','F','Catalysis of the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.','2013-10-27','NSRP'),(9463,15192,'L-phenylalanine transmembrane transporter activity','F','Catalysis of the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.','2013-10-27','NSRP'),(9464,15193,'L-proline transmembrane transporter activity','F','Catalysis of the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.','2013-10-27','NSRP'),(9465,15194,'L-serine transmembrane transporter activity','F','Catalysis of the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.','2013-10-27','NSRP'),(9466,15195,'L-threonine transmembrane transporter activity','F','Catalysis of the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.','2013-10-27','NSRP'),(9467,15196,'L-tryptophan transmembrane transporter activity','F','Catalysis of the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.','2013-10-27','NSRP'),(9468,15197,'peptide transporter activity','F','Enables the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9469,15198,'oligopeptide transporter activity','F','Enables the directed movement of oligopeptides into, out of or within a cell, or between cells. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.','2013-10-27','NSRP'),(9470,15199,'amino-acid betaine transmembrane transporter activity','F','Catalysis of the transfer of betaine, the N-trimethyl derivative of an amino acid, from one side of the membrane to the other.','2013-10-27','NSRP'),(9471,15200,'methylammonium transmembrane transporter activity','F','Enables the directed movement of methylammonium, CH3NH2, into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9472,15203,'polyamine transmembrane transporter activity','F','Catalysis of the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other.','2013-10-27','NSRP'),(9473,15204,'urea transmembrane transporter activity','F','Enables the directed movement of urea cross a membrane into, out of or within a cell, or between cells. Urea is the water soluble compound H2N-CO-NH2.','2013-10-27','NSRP'),(9474,15205,'nucleobase transmembrane transporter activity','F','Catalysis of the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.','2013-10-27','NSRP'),(9475,15207,'adenine transmembrane transporter activity','F','Catalysis of the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.','2013-10-27','NSRP'),(9476,15208,'guanine transmembrane transporter activity','F','Catalysis of the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.','2013-10-27','NSRP'),(9477,15209,'cytosine transmembrane transporter activity','F','Catalysis of the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.','2013-10-27','NSRP'),(9478,15210,'uracil transmembrane transporter activity','F','Catalysis of the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.','2013-10-27','NSRP'),(9479,15211,'purine nucleoside transmembrane transporter activity','F','Catalysis of the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.','2013-10-27','NSRP'),(9480,15212,'cytidine transmembrane transporter activity','F','Catalysis of the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.','2013-10-27','NSRP'),(9481,15213,'uridine transmembrane transporter activity','F','Catalysis of the transfer of uridine, uracil riboside, from one side of a membrane to the other.','2013-10-27','NSRP'),(9482,15214,'pyrimidine nucleoside transmembrane transporter activity','F','Catalysis of the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.','2013-10-27','NSRP'),(9483,15215,'nucleotide transmembrane transporter activity','F','Catalysis of the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.','2013-10-27','NSRP'),(9484,15216,'purine nucleotide transmembrane transporter activity','F','Catalysis of the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.','2013-10-27','NSRP'),(9485,15217,'ADP transmembrane transporter activity','F','Catalysis of the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.','2013-10-27','NSRP'),(9486,15218,'pyrimidine nucleotide transmembrane transporter activity','F','Catalysis of the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.','2013-10-27','NSRP'),(9487,15219,'protein-DNA complex transmembrane transporter activity','F','Catalysis of the transfer of protein-DNA complexes from one side of a membrane to the other.','2013-10-27','NSRP'),(9488,15220,'choline transmembrane transporter activity','F','Catalysis of the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.','2013-10-27','NSRP'),(9489,15221,'lipopolysaccharide transmembrane transporter activity','F','Catalysis of the transfer of lipopolysaccharides from one side of the membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.','2013-10-27','NSRP'),(9490,15222,'serotonin transmembrane transporter activity','F','Catalysis of the transfer of serotonin from one side of the membrane to the other. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.','2013-10-27','NSRP'),(9491,15223,'vitamin or cofactor transporter activity','F','OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9492,15224,'biopterin transporter activity','F','Enables the directed movement of biopterin into, out of or within a cell, or between cells. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.','2013-10-27','NSRP'),(9493,15225,'biotin transporter activity','F','Enables the directed movement of biotin into, out of or within a cell, or between cells. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.','2013-10-27','NSRP'),(9494,15226,'carnitine transmembrane transporter activity','F','Enables the directed movement of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.','2013-10-27','NSRP'),(9495,15227,'acyl carnitine transmembrane transporter activity','F','Enables the directed movement of acyl carnitine across a membrane. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.','2013-10-27','NSRP'),(9496,15228,'coenzyme A transmembrane transporter activity','F','Enables the directed movement of coenzyme A across a membrane into, out of or within a cell, or between cells. Coenzyme A, 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.','2013-10-27','NSRP'),(9497,15229,'L-ascorbic acid transporter activity','F','Enables the directed movement of L-ascorbate into, out of or within a cell, or between cells. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.','2013-10-27','NSRP'),(9498,15230,'FAD transmembrane transporter activity','F','Enables the directed movement of flavin-adenine dinucleotide (FAD) across a membrane into, out of or within a cell, or between cells. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.','2013-10-27','NSRP'),(9499,15231,'5-formyltetrahydrofolate transporter activity','F','Enables the directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells.','2013-10-27','NSRP'),(9500,15232,'heme transporter activity','F','Enables the directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9501,15233,'pantothenate transmembrane transporter activity','F','Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.','2013-10-27','NSRP'),(9502,15234,'thiamine transmembrane transporter activity','F','Catalysis of the transfer of thiamine from one side of the membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.','2013-10-27','NSRP'),(9503,15235,'cobalamin transporter activity','F','Enables the directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell.','2013-10-27','NSRP'),(9504,15238,'drug transmembrane transporter activity','F','Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.','2013-10-27','NSRP'),(9505,15240,'amiloride transporter activity','F','Enables the directed movement of amiloride into, out of or within a cell, or between cells. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.','2013-10-27','NSRP'),(9506,15241,'aminotriazole transporter activity','F','Enables the directed movement of aminotriazole into, out of or within a cell, or between cells. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.','2013-10-27','NSRP'),(9507,15242,'benomyl transporter activity','F','Enables the directed movement of benomyl into, out of or within a cell, or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.','2013-10-27','NSRP'),(9508,15243,'cycloheximide transporter activity','F','Enables the directed movement of cycloheximide into, out of or within a cell, or between cells. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.','2013-10-27','NSRP'),(9509,15244,'fluconazole transporter activity','F','Enables the directed movement of fluconazole into, out of or within a cell, or between cells. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.','2013-10-27','NSRP'),(9510,15245,'fatty acid transporter activity','F','Enables the directed movement of fatty acids into, out of or within a cell, or between cells. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.','2013-10-27','NSRP'),(9511,15246,'fatty-acyl group transporter activity','F','Enables the directed movement of a fatty acyl group into, out of or within a cell, or between cells. A fatty acyl group is any acyl group derived from a fatty acid.','2013-10-27','NSRP'),(9512,15247,'aminophospholipid transporter activity','F','Enables the directed movement of aminophospholipids into, out of or within a cell, or between cells. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.','2013-10-27','NSRP'),(9513,15248,'sterol transporter activity','F','Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.','2013-10-27','NSRP'),(9514,15250,'water channel activity','F','Transport systems of this type catalyze facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9515,15251,'ammonium channel activity','F','Catalysis of facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9516,15252,'hydrogen ion channel activity','F','Catalysis of facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9517,15253,'sugar/polyol channel activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9518,15254,'glycerol channel activity','F','Catalysis of facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9519,15255,'propanediol channel activity','F','Catalysis of facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9520,15256,'monocarboxylate channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9521,15257,'organic anion channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9522,15258,'gluconate channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9523,15259,'glutamate channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9524,15260,'isethionate channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9525,15261,'lactate channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9526,15262,'taurine channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9527,15263,'amine/amide/polyamine channel activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9528,15264,'methylammonium channel activity','F','Catalysis of facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2.','2013-10-27','NSRP'),(9529,15265,'urea channel activity','F','Catalysis of facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(9530,15266,'protein channel activity','F','Catalysis of energy-independent facilitated diffusion, mediated by passage of proteins through a transmembrane aqueous pore or channel.','2013-10-27','NSRP'),(9531,15267,'channel activity','F','Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.','2013-10-27','NSRP'),(9532,15269,'calcium-activated potassium channel activity','F','Catalysis of the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.','2013-10-27','NSRP'),(9533,15271,'outward rectifier potassium channel activity','F','Catalysis of the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.','2013-10-27','NSRP'),(9534,15272,'ATP-activated inward rectifier potassium channel activity','F','Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.','2013-10-27','NSRP'),(9535,15274,'organellar voltage-gated chloride channel activity','F','Catalysis of the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.','2013-10-27','NSRP'),(9536,15275,'stretch-activated, cation-selective, calcium channel activity','F','Catalysis of the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.','2013-10-27','NSRP'),(9537,15276,'ligand-gated ion channel activity','F','Catalysis of the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(9538,15277,'kainate selective glutamate receptor activity','F','An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.','2013-10-27','NSRP'),(9539,15278,'calcium-release channel activity','F','Catalysis of the transmembrane transfer of a calcium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(9540,15279,'store-operated calcium channel activity','F','A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.','2013-10-27','NSRP'),(9541,15280,'ligand-gated sodium channel activity','F','Catalysis of the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(9542,15282,'NADPH oxidase-associated cytochrome b558 hydrogen channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9543,15283,'apoptogenic cytochrome c release channel activity','F','OBSOLETE.','2013-10-27','NSRP'),(9544,15284,'fructose uniporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).','2013-10-27','NSRP'),(9545,15288,'porin activity','F','Catalysis of the transfer of substances, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.','2013-10-27','NSRP'),(9546,15289,'pore-forming toxin activity','F','OBSOLETE. Catalysis of the transport of electrolytes and other small molecules across a cell membrane. They are synthesized by one cell and secreted for insertion into the membrane of another cell where they form transmembrane pores. They may exert their toxic effects by allowing the free flow of electrolytes and other small molecules across the membrane, or they may allow entry into the target cell cytoplasm of a toxin protein that ultimately kills the cell.','2013-10-27','NSRP'),(9547,15291,'secondary active transmembrane transporter activity','F','Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.','2013-10-27','NSRP'),(9548,15292,'uniporter activity','F','Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.','2013-10-27','NSRP'),(9549,15293,'symporter activity','F','Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.','2013-10-27','NSRP'),(9550,15294,'solute:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).','2013-10-27','NSRP'),(9551,15295,'solute:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).','2013-10-27','NSRP'),(9552,15296,'anion:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).','2013-10-27','NSRP'),(9553,15297,'antiporter activity','F','Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).','2013-10-27','NSRP'),(9554,15298,'solute:cation antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out).','2013-10-27','NSRP'),(9555,15299,'solute:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).','2013-10-27','NSRP'),(9556,15300,'solute:solute antiporter activity','F','Catalysis of the reaction: solute A(out) + solute B(in) = solute A(in) + solute B(out).','2012-03-14','NSRP'),(9557,15301,'anion:anion antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).','2013-10-27','NSRP'),(9558,15303,'galactose, glucose uniporter activity','F','OBSOLETE. Catalysis of the reaction: galactose or glucose(out) = galactose or glucose(in).','2013-10-27','NSRP'),(9559,15304,'glucose uniporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in).','2013-10-27','NSRP'),(9560,15305,'lactose, galactose:hydrogen symporter activity','F','OBSOLETE. Catalysis of the reaction: (lactose or galactose)(out) + H+(out) = (lactose or galactose)(in) + H+(in).','2013-10-27','NSRP'),(9561,15306,'sialate:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).','2013-10-27','NSRP'),(9562,15307,'drug:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).','2013-10-27','NSRP'),(9563,15308,'amiloride:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out).','2013-10-27','NSRP'),(9564,15309,'cycloheximide:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).','2013-10-27','NSRP'),(9565,15310,'benomyl:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).','2013-10-27','NSRP'),(9566,15311,'monoamine:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).','2013-10-27','NSRP'),(9567,15312,'polyamine:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).','2013-10-27','NSRP'),(9568,15313,'fluconazole:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).','2013-10-27','NSRP'),(9569,15314,'aminotriazole:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).','2013-10-27','NSRP'),(9570,15315,'organophosphate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out).','2013-10-27','NSRP'),(9571,15316,'nitrite/nitrate porter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9572,15317,'phosphate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).','2013-10-27','NSRP'),(9573,15318,'inorganic solute uptake transmembrane transporter activity','F','Catalysis of the transfer of an inorganic solute from the outside of a cell to the inside of the cell across a membrane.','2013-10-27','NSRP'),(9574,15319,'sodium:inorganic phosphate symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in).','2013-10-27','NSRP'),(9575,15320,'phosphate ion carrier activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate (cyt) + H+ (cyt) = phosphate (mitochondrion) + H+ (mitochondrion).','2013-10-27','NSRP'),(9576,15321,'sodium-dependent phosphate transmembrane transporter activity','F','Catalysis of the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other, requiring sodium ions.','2013-10-27','NSRP'),(9577,15322,'secondary active oligopeptide transmembrane transporter activity','F','Catalysis of the transfer of an oligopeptide or oligopeptides from one side of the membrane to the other, up the solute\'s concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.','2013-10-27','NSRP'),(9578,15323,'type V protein secretor activity','F','OBSOLETE.','2013-10-27','NSRP'),(9579,15324,'peptide-acetyl-CoA secondary active transmembrane transporter activity','F','Catalysis of the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.','2013-10-27','NSRP'),(9580,15325,'acetyl-CoA:CoA antiporter activity','F','Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).','2013-10-27','NSRP'),(9581,15326,'cationic amino acid transmembrane transporter activity','F','Catalysis of the transfer of a positively charged amino acid from one side of the membrane to the other.','2013-10-27','NSRP'),(9582,15327,'cystine:glutamate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).','2013-10-27','NSRP'),(9583,15328,'cystine secondary active transmembrane transporter activity','F','Catalysis of the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.','2013-10-27','NSRP'),(9584,15330,'high affinity glutamine transmembrane transporter activity','F','Catalysis of the high affinity transfer of glutamine from one side of the membrane to the other.','2013-10-27','NSRP'),(9585,15331,'asparagine/glutamine permease activity','F','OBSOLETE. Catalysis of the stereospecific transfer of asparagine or glutamine across a biological membrane.','2013-10-27','NSRP'),(9586,15332,'leucine/valine/isoleucine permease activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9587,15333,'peptide:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in). Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.','2013-10-27','NSRP'),(9588,15334,'high affinity oligopeptide transporter activity','F','Catalysis of the transfer of oligopeptide from one side of the membrane to the other. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.','2013-10-27','NSRP'),(9589,15335,'heavy metal ion:hydrogen symporter activity','F','OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in), where Me2+ is Fe2+, Zn2+, Mn2+, Cu2+, Cd2+, Co2+, Ni2+ or Pb2+.','2013-10-27','NSRP'),(9590,15336,'high affinity metal ion uptake transporter activity','F','OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Fe2+, Mn2+, Zn2+, Cu2+, Cd2+, Ni2+ or Co2+.','2013-10-27','NSRP'),(9591,15337,'low affinity metal ion uptake transporter activity','F','OBSOLETE. Catalysis of the reaction: Me2+(out) + H+(out) = Me2+(in) + H+(in). Me can be Mn2+ or Cu2+.','2013-10-27','NSRP'),(9592,15339,'cobalt, zinc uptake permease activity','F','OBSOLETE. Catalysis of the reaction: (Zn2+ or Co2+)(out) = (Zn2+ or Co2+)(in). The activity is driven by proton motive force, possibly by proton symport.','2013-10-27','NSRP'),(9593,15340,'zinc, cadmium uptake permease activity','F','OBSOLETE. Catalysis of the reaction: (Zn2+ or Cd2+)(out) = (Zn2+ or Cd2+)(in). The activity is driven by proton motive force, possibly by proton symport.','2013-10-27','NSRP'),(9594,15341,'zinc efflux active transmembrane transporter activity','F','Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.','2013-10-27','NSRP'),(9595,15342,'zinc, iron permease activity','F','OBSOLETE. Catalysis of the reaction: (Zn2+ or Fe2+)(out) = (Zn2+ or Fe2+)(in), probably powered by proton motive force.','2013-10-27','NSRP'),(9596,15343,'siderophore transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).','2013-10-27','NSRP'),(9597,15344,'siderophore uptake transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).','2013-10-27','NSRP'),(9598,15345,'ferric enterobactin:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).','2013-10-27','NSRP'),(9599,15346,'ferric triacetylfusarinine C:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).','2013-10-27','NSRP'),(9600,15347,'sodium-independent organic anion transmembrane transporter activity','F','Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.','2013-10-27','NSRP'),(9601,15348,'prostaglandin/thromboxane transporter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9602,15349,'thyroid hormone transmembrane transporter activity','F','Catalysis of the transfer of thyroid hormones from one side of the membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.','2013-10-27','NSRP'),(9603,15350,'methotrexate transporter activity','F','Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.','2013-10-27','NSRP'),(9604,15351,'bilirubin secondary active transmembrane transporter activity','F','Catalysis of the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.','2013-10-27','NSRP'),(9605,15352,'secondary active sterol transmembrane transporter activity','F','Catalysis of the transfer of sterol from one side of the membrane to the other, up the solute\'s concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.','2013-10-27','NSRP'),(9606,15355,'secondary active monocarboxylate transmembrane transporter activity','F','Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.','2013-10-27','NSRP'),(9607,15356,'monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9608,15358,'amino acid/choline transmembrane transporter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9609,15360,'acetate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).','2013-10-27','NSRP'),(9610,15361,'low affinity sodium:dicarboxylate symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.','2013-10-27','NSRP'),(9611,15362,'high affinity sodium:dicarboxylate symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(9612,15363,'dicarboxylate (succinate/fumarate/malate) antiporter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9613,15364,'dicarboxylate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out).','2013-10-27','NSRP'),(9614,15366,'malate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).','2013-10-27','NSRP'),(9615,15367,'oxoglutarate:malate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).','2013-10-27','NSRP'),(9616,15368,'calcium:cation antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).','2013-10-27','NSRP'),(9617,15369,'calcium:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).','2013-10-27','NSRP'),(9618,15370,'solute:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).','2013-10-27','NSRP'),(9619,15371,'galactose:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).','2013-10-27','NSRP'),(9620,15372,'glutamate/aspartate:sodium symporter activity','F','OBSOLETE. Catalysis of the reaction: (glutamate or aspartate)(out) + Na+(out) = (glutamate or aspartate)(in) + Na+(in).','2013-10-27','NSRP'),(9621,15373,'monovalent anion:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in).','2013-10-27','NSRP'),(9622,15374,'neutral, cationic amino acid:sodium:chloride symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/cationic amino acid(out) + Na+(out) + Cl-(out) = neutral/cationic amino acid(in) + Na+(in) + Cl-(in).','2013-10-27','NSRP'),(9623,15375,'glycine:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).','2013-10-27','NSRP'),(9624,15376,'betaine/GABA:sodium symporter activity','F','OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in).','2013-10-27','NSRP'),(9625,15377,'cation:chloride symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).','2013-10-27','NSRP'),(9626,15378,'sodium:chloride symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).','2013-10-27','NSRP'),(9627,15379,'potassium:chloride symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).','2013-10-27','NSRP'),(9628,15381,'high affinity sulfate transmembrane transporter activity','F','Catalysis of the secondary active high affinity transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(9629,15382,'sodium:sulfate symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).','2013-10-27','NSRP'),(9630,15383,'sulfate:bicarbonate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).','2013-10-27','NSRP'),(9631,15385,'sodium:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).','2013-10-27','NSRP'),(9632,15386,'potassium:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).','2013-10-27','NSRP'),(9633,15387,'potassium:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).','2013-10-27','NSRP'),(9634,15388,'potassium uptake transmembrane transporter activity','F','Catalysis of the transfer of potassium from the outside of a cell to the inside of the cell across a membrane: K+(out) + energy = K+(in).','2013-10-27','NSRP'),(9635,15389,'pyrimidine- and adenine-specific:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in).','2013-10-27','NSRP'),(9636,15390,'purine-specific nucleoside:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).','2013-10-27','NSRP'),(9637,15391,'nucleobase:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).','2013-10-27','NSRP'),(9638,15393,'uracil/uridine permease activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9639,15394,'uridine:hydrogen ion symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).','2013-10-27','NSRP'),(9640,15395,'nucleoside transmembrane transporter activity, down a concentration gradient','F','Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.','2013-10-27','NSRP'),(9641,15398,'high affinity secondary active ammonium transmembrane transporter activity','F','Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(9642,15399,'primary active transmembrane transporter activity','F','Catalysis of the transfer of a solute from one side of the membrane to the other, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.','2013-10-27','NSRP'),(9643,15400,'low affinity secondary active ammonium transmembrane transporter activity','F','Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In low affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.','2013-10-27','NSRP'),(9644,15401,'urea:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).','2013-10-27','NSRP'),(9645,15403,'thiamine uptake transmembrane transporter activity','F','Catalysis of the transfer of thiamine from the outside of a cell to the inside across a membrane.','2013-10-27','NSRP'),(9646,15405,'P-P-bond-hydrolysis-driven transmembrane transporter activity','F','Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.','2013-10-27','NSRP'),(9647,15406,'ABC-type uptake permease activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9648,15407,'monosaccharide-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.','2013-10-27','NSRP'),(9649,15408,'ferric-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).','2013-10-27','NSRP'),(9650,15410,'manganese-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).','2013-10-27','NSRP'),(9651,15411,'taurine-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).','2013-10-27','NSRP'),(9652,15412,'molybdate transmembrane-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).','2013-10-27','NSRP'),(9653,15413,'nickel-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).','2013-10-27','NSRP'),(9654,15414,'nitrate transmembrane-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).','2013-10-27','NSRP'),(9655,15415,'phosphate ion transmembrane-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).','2013-10-27','NSRP'),(9656,15416,'organic phosphonate transmembrane-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).','2013-10-27','NSRP'),(9657,15417,'polyamine-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).','2013-10-27','NSRP'),(9658,15418,'quaternary-ammonium-compound-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).','2013-10-27','NSRP'),(9659,15419,'sulfate transmembrane-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).','2013-10-27','NSRP'),(9660,15420,'cobalamin-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + cob(III)alamin(out) = ADP + phosphate + cob(III)alamin(in). Cobalamin is also known as vitamin B12.','2013-10-27','NSRP'),(9661,15421,'oligopeptide-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).','2013-10-27','NSRP'),(9662,15422,'oligosaccharide-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).','2013-10-27','NSRP'),(9663,15423,'maltose-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).','2013-10-27','NSRP'),(9664,15424,'amino acid-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).','2013-10-27','NSRP'),(9665,15425,'nonpolar-amino acid-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).','2013-10-27','NSRP'),(9666,15426,'polar-amino acid-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).','2013-10-27','NSRP'),(9667,15427,'ABC-type efflux porter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9668,15428,'type I protein secretor activity','F','OBSOLETE.','2013-10-27','NSRP'),(9669,15429,'peroxisomal fatty acyl transporter','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9670,15430,'glycerol-3-phosphate-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).','2013-10-27','NSRP'),(9671,15431,'glutathione S-conjugate-exporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).','2013-10-27','NSRP'),(9672,15432,'bile acid-exporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.','2013-10-27','NSRP'),(9673,15433,'peptide antigen-transporting ATPase activity','F','Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.','2013-10-27','NSRP'),(9674,15434,'cadmium-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).','2013-10-27','NSRP'),(9675,15435,'ABC-type efflux permease activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9676,15436,'capsular-polysaccharide-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).','2013-10-27','NSRP'),(9677,15437,'lipopolysaccharide-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipopolysaccharide(in) = ADP + phosphate + lipopolysaccharide(out).','2013-10-27','NSRP'),(9678,15438,'teichoic-acid-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).','2013-10-27','NSRP'),(9679,15439,'heme-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).','2013-10-27','NSRP'),(9680,15440,'peptide-transporting ATPase activity','F','Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.','2013-10-27','NSRP'),(9681,15441,'beta-glucan-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).','2013-10-27','NSRP'),(9682,15442,'hydrogen-/sodium-translocating ATPase activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + (Na+ or H+)(in) = ADP + phosphate + (Na+ or H+)(out).','2013-10-27','NSRP'),(9683,15443,'sodium-transporting two-sector ATPase activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out).','2013-10-27','NSRP'),(9684,15444,'magnesium-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in).','2013-10-27','NSRP'),(9685,15445,'silver-exporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out).','2013-10-27','NSRP'),(9686,15446,'arsenite-transmembrane transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).','2013-10-27','NSRP'),(9687,15447,'type II protein secretor activity','F','OBSOLETE.','2013-10-27','NSRP'),(9688,15448,'type III protein (virulence-related) secretor activity','F','OBSOLETE.','2013-10-27','NSRP'),(9689,15449,'type IV protein (DNA-protein) secretor activity','F','OBSOLETE.','2013-10-27','NSRP'),(9690,15450,'P-P-bond-hydrolysis-driven protein transmembrane transporter activity','F','Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.','2013-10-27','NSRP'),(9691,15451,'decarboxylation-driven active transmembrane transporter activity','F','Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.','2013-10-27','NSRP'),(9692,15452,'methyl transfer-driven active transmembrane transporter activity','F','Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.','2013-10-27','NSRP'),(9693,15453,'oxidoreduction-driven active transmembrane transporter activity','F','Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.','2013-10-27','NSRP'),(9694,15454,'light-driven active transmembrane transporter activity','F','Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute\'s concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.','2013-10-27','NSRP'),(9695,15459,'potassium channel regulator activity','F','Modulates the activity of a potassium channel.','2013-10-27','NSRP'),(9696,15461,'endosomal oligosaccharide transporter','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9697,15462,'protein-transmembrane transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).','2013-10-27','NSRP'),(9698,15464,'acetylcholine receptor activity','F','Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(9699,15465,'lysin activity','F','OBSOLETE. An agent that can lyse cells.','2013-10-27','NSRP'),(9700,15466,'autolysin activity','F','OBSOLETE. An agent that can lyse the cell in which it is synthesized.','2013-10-27','NSRP'),(9701,15467,'G-protein activated inward rectifier potassium channel activity','F','Catalysis of the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.','2013-10-27','NSRP'),(9702,15468,'colicin','F','OBSOLETE. Plasmid-encoded bacteriocins which are produced by enteric bacteria. Exert a lethal effect on other bacteria including E. coli strains that lack the Col plasmid. Bind to a cell surface receptor and are transported into the periplasm via an energy-dependent process involving a TonB- or TolA-dependent hetero-oligomeric protein complex. Some colicins kill their target cell by inserting into the cytoplasmic membrane where they form voltage-sensitive (trans-negative) channels that depolarize and deenergize the cell, and thereby kill it.','2013-10-27','NSRP'),(9703,15469,'channel-forming toxin activity','F','OBSOLETE. A toxin that exerts its effects by forming a channel in a membrane that allows the unregulated passage of substances into and out of the cell.','2013-10-27','NSRP'),(9704,15470,'bacteriocin activity','F','OBSOLETE. Polypeptide antibiotic secreted by bacteria and able to kill bacteria of susceptible strains after absorption by specific cell surface receptor.','2013-10-27','NSRP'),(9705,15471,'nucleoside-specific channel forming porin activity','F','Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.','2013-10-27','NSRP'),(9706,15472,'fimbrium-specific chaperone activity','F','OBSOLETE. Assists in the correct assembly of fimbria, extracellular organelles that are used to attach a bacterial cell to a surface, but is not a component of the fimbrium when performing its normal biological function.','2013-10-27','NSRP'),(9707,15473,'fimbrial usher porin activity','F','A porin that acts in the assembly of fimbria together with fimbrial chaperone.','2013-10-27','NSRP'),(9708,15474,'autotransporter activity','F','Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.','2013-10-27','NSRP'),(9709,15475,'adhesin autotransporter activity','F','Catalysis of the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.','2013-10-27','NSRP'),(9710,15476,'hemaglutinin autotransporter activity','F','Catalysis of the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.','2013-10-27','NSRP'),(9711,15477,'receptor porin activity','F','OBSOLETE. A porin of the bacterial outer membrane that forms transmembrane pores and transports relatively large molecules from the external milieu to the periplasm in an energized process. Energizing of transport across the outer membrane requires a heterotrimeric complex of proteins, the TonB-ExbB-ExbD complex, or in some cases, the TolA-TolQ-TolR complex. Energizing requires proton motive force across the cytoplasmic membrane.','2013-10-27','NSRP'),(9712,15478,'oligosaccharide transporting porin activity','F','Catalysis of the transfer of oligosaccharide, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.','2013-10-27','NSRP'),(9713,15479,'outer membrane exporter porin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9714,15480,'secretin (sensu Bacteria)','F','OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm).','2013-10-27','NSRP'),(9715,15481,'maltose transporting porin activity','F','Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.','2013-10-27','NSRP'),(9716,15482,'voltage-gated anion channel porin activity','F','OBSOLETE.','2013-10-27','NSRP'),(9717,15483,'long-chain fatty acid transporting porin activity','F','Catalysis of the transfer of long-chain fatty acids from one side of the membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.','2013-10-27','NSRP'),(9718,15484,'hemolysin activity','F','OBSOLETE. Any substance that causes the lysis of red blood cells.','2013-10-27','NSRP'),(9719,15485,'cholesterol binding','F','Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(9720,15486,'glycoside-pentoside-hexuronide:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.','2013-10-27','NSRP'),(9721,15487,'melibiose:monovalent cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).','2013-10-27','NSRP'),(9722,15488,'glucuronide:monovalent cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).','2013-10-27','NSRP'),(9723,15489,'putrescine transmembrane transporter activity','F','Catalysis of the transfer of putrescine from one side of the membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.','2013-10-27','NSRP'),(9724,15490,'cadaverine transmembrane transporter activity','F','Catalysis of the transfer of cadaverine, 1,5-pentanediamine, from one side of the membrane to the other.','2013-10-27','NSRP'),(9725,15491,'cation:cation antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).','2013-10-27','NSRP'),(9726,15492,'phenylalanine:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).','2013-10-27','NSRP'),(9727,15493,'lysine:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).','2013-10-27','NSRP'),(9728,15494,'aromatic amino acid:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).','2013-10-27','NSRP'),(9729,15495,'gamma-aminobutyric acid:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).','2013-10-27','NSRP'),(9730,15496,'putrescine:ornithine antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).','2013-10-27','NSRP'),(9731,15498,'pantothenate:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).','2013-10-27','NSRP'),(9732,15499,'formate transmembrane transporter activity','F','Catalysis of the transfer of formate from one side of the membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.','2013-10-27','NSRP'),(9733,15500,'threonine/serine:sodium symporter activity','F','OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in).','2013-10-27','NSRP'),(9734,15501,'glutamate:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).','2013-10-27','NSRP'),(9735,15503,'glutathione-regulated potassium exporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.','2013-10-27','NSRP'),