(9736,15504,'cytosine:hydrogen ion symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).','2013-10-27','NSRP'),(9737,15505,'uracil:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).','2013-10-27','NSRP'),(9738,15506,'nucleoside:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).','2013-10-27','NSRP'),(9739,15507,'hydroxy/aromatic amino acid permease activity','F','OBSOLETE. Permease for hydroxy and aromatic amino acids.','2013-10-27','NSRP'),(9740,15513,'nitrite uptake transmembrane transporter activity','F','Catalysis of the transfer of nitrite from the outside of a cell to the inside of the cell across a membrane.','2013-10-27','NSRP'),(9741,15514,'nitrite efflux transmembrane transporter activity','F','Catalysis of the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(9742,15515,'citrate:succinate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).','2013-10-27','NSRP'),(9743,15516,'tartrate:succinate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).','2013-10-27','NSRP'),(9744,15517,'galactose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).','2013-10-27','NSRP'),(9745,15518,'arabinose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).','2013-10-27','NSRP'),(9746,15519,'D-xylose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).','2013-10-27','NSRP'),(9747,15520,'tetracycline:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).','2013-10-27','NSRP'),(9748,15521,'bicyclomycin/sulfathiazole:hydrogen antiporter activity','F','OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in).','2013-10-27','NSRP'),(9749,15522,'hydrophobic uncoupler:hydrogen antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.','2013-10-27','NSRP'),(9750,15523,'arabinose efflux transmembrane transporter activity','F','Catalysis of the transfer of arabinose from the inside of the cell to the outside of the cell across a membrane: H+(out) + arabinose(in) = H+(in) + arabinose(out).','2013-10-27','NSRP'),(9751,15524,'L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity','F','OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out).','2013-10-27','NSRP'),(9752,15525,'carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9753,15526,'hexose-phosphate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out).','2013-10-27','NSRP'),(9754,15527,'glycerol-phosphate:inorganic phosphate antiporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out).','2013-10-27','NSRP'),(9755,15528,'lactose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).','2013-10-27','NSRP'),(9756,15529,'raffinose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).','2013-10-27','NSRP'),(9757,15530,'shikimate transmembrane transporter activity','F','Catalysis of the transfer of shikimate from one side of the membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.','2013-10-27','NSRP'),(9758,15531,'citrate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).','2013-10-27','NSRP'),(9759,15532,'alpha-ketoglutarate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).','2013-10-27','NSRP'),(9760,15533,'shikimate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).','2013-10-27','NSRP'),(9761,15534,'proline/glycine/betaine:hydrogen/sodium symporter activity','F','OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).','2013-10-27','NSRP'),(9762,15535,'fucose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).','2013-10-27','NSRP'),(9763,15537,'xanthosine:hydrogen ion symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).','2013-10-27','NSRP'),(9764,15538,'sialic acid:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).','2013-10-27','NSRP'),(9765,15539,'hexuronate:cation symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.','2013-10-27','NSRP'),(9766,15540,'3-hydroxyphenyl propionate:hydrogen ion symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).','2013-10-27','NSRP'),(9767,15541,'secondary active cyanate uptake transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cyanate(out) = cyanate(in).','2013-10-27','NSRP'),(9768,15542,'sugar efflux transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(in) = sugar(out).','2013-10-27','NSRP'),(9769,15543,'lactose/glucose efflux transporter activity','F','OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out).','2013-10-27','NSRP'),(9770,15544,'phenyl propionate uptake uniporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenyl propionate(out) = phenyl propionate(in).','2013-10-27','NSRP'),(9771,15545,'bicyclomycin transporter activity','F','Enables the directed movement of bicyclomycin into, out of or within a cell, or between cells. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.','2013-10-27','NSRP'),(9772,15546,'sulfathiazole transmembrane transporter activity','F','Enables the directed movement of sulfathiazole across a membrane. Sulfathiazole is an antibacterial agent of the sulfonamide group.','2013-10-27','NSRP'),(9773,15547,'nalidixic acid transporter activity','F','Enables the directed movement of nalidixic acid into, out of or within a cell, or between cells. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.','2013-10-27','NSRP'),(9774,15548,'organomercurial transporter activity','F','Enables the directed movement of organomercurial compounds into, out of or within a cell, or between cells. Organomercurial substances are any organic compound containing a mercury atom.','2013-10-27','NSRP'),(9775,15549,'carbonyl cyanide m-chlorophenylhydrazone transporter activity','F','Enables the directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.','2013-10-27','NSRP'),(9776,15550,'galacturonate transmembrane transporter activity','F','Catalysis of the transfer of galacturonate from one side of the membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.','2013-10-27','NSRP'),(9777,15551,'3-hydroxyphenyl propanoate transmembrane transporter activity','F','Catalysis of the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other.','2013-10-27','NSRP'),(9778,15552,'propionate transmembrane transporter activity','F','Catalysis of the transfer of propionate from one side of the membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.','2013-10-27','NSRP'),(9779,15553,'xanthosine transmembrane transporter activity','F','Catalysis of the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.','2013-10-27','NSRP'),(9780,15554,'tartrate transmembrane transporter activity','F','Catalysis of the transfer of tartrate from one side of the membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.','2013-10-27','NSRP'),(9781,15556,'C4-dicarboxylate transmembrane transporter activity','F','Catalysis of the transfer of C4-dicarboxylate from one side of the membrane to the other.','2013-10-27','NSRP'),(9782,15557,'arginine targeting transmembrane transporter activity','F','Enables the directed movement of fully folded proteins into, out of or within a cell, or between cells, by targeting the proteins to the transporter via a specialized N-terminal twin arginine signal peptide.','2013-10-27','NSRP'),(9783,15558,'p-aminobenzoyl-glutamate uptake transmembrane transporter activity','F','Catalysis of the transfer of p-aminobenzoyl-glutamate from the outside of a cell to the inside of the cell across a membrane.','2013-10-27','NSRP'),(9784,15560,'L-idonate/D-gluconate:hydrogen symporter activity','F','OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in).','2013-10-27','NSRP'),(9785,15561,'rhamnose:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).','2013-10-27','NSRP'),(9786,15562,'efflux transmembrane transporter activity','F','Catalysis of the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(9787,15563,'uptake transmembrane transporter activity','F','Catalysis of the transfer of a specific substance or related group of substances from the outside of a cell to the inside across a membrane.','2013-10-27','NSRP'),(9788,15565,'threonine efflux transmembrane transporter activity','F','Catalysis of the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(9789,15566,'acriflavine transporter activity','F','Enables the directed movement of acriflavin into, out of or within a cell, or between cells. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.','2013-10-27','NSRP'),(9790,15567,'alkane transporter activity','F','Enables the directed movement of alkanes into, out of or within a cell, or between cells. Alkanes are saturated aliphatic hydrocarbon compounds.','2013-10-27','NSRP'),(9791,15568,'L-idonate transmembrane transporter activity','F','Catalysis of the transfer of L-idonate from one side of the membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.','2013-10-27','NSRP'),(9792,15569,'p-aminobenzoyl-glutamate transmembrane transporter activity','F','Catalysis of the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.','2013-10-27','NSRP'),(9793,15571,'N-acetylgalactosamine transmembrane transporter activity','F','Catalysis of the transfer of N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.','2013-10-27','NSRP'),(9794,15572,'N-acetylglucosamine transmembrane transporter activity','F','Catalysis of the transfer of N-acetylglucosamine from one side of the membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.','2013-10-27','NSRP'),(9795,15573,'beta-glucoside transmembrane transporter activity','F','Catalysis of the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.','2013-10-27','NSRP'),(9796,15574,'trehalose transmembrane transporter activity','F','Catalysis of the transfer of trehalose from one side of the membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.','2013-10-27','NSRP'),(9797,15575,'mannitol transmembrane transporter activity','F','Catalysis of the transfer of mannitol from one side of the membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.','2013-10-27','NSRP'),(9798,15576,'sorbitol transmembrane transporter activity','F','Catalysis of the transfer of sorbitol from one side of the membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.','2013-10-27','NSRP'),(9799,15577,'galactitol transmembrane transporter activity','F','Catalysis of the transfer of a galactitol from one side of the membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.','2013-10-27','NSRP'),(9800,15578,'mannose transmembrane transporter activity','F','Catalysis of the transfer of mannose from one side of the membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.','2013-10-27','NSRP'),(9801,15583,'beta-glucoside [arbutin-salicin-cellobiose] permease activity','F','OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose.','2013-10-27','NSRP'),(9802,15591,'D-ribose transmembrane transporter activity','F','Catalysis of the transfer of D-ribose from one side of the membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.','2013-10-27','NSRP'),(9803,15592,'methylgalactoside transmembrane transporter activity','F','Catalysis of the transfer of methylgalactoside from one side of the membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.','2013-10-27','NSRP'),(9804,15593,'allose transmembrane transporter activity','F','Catalysis of the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.','2013-10-27','NSRP'),(9805,15594,'putrescine-importing ATPase activity','F','Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).','2013-10-27','NSRP'),(9806,15595,'spermidine-importing ATPase activity','F','Catalysis of the reaction: ATP + H2O + spermidine(out) -> ADP + phosphate + spermidine(in).','2013-10-27','NSRP'),(9807,15596,'glycine betaine/proline porter activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).','2013-10-27','NSRP'),(9808,15597,'histidine/arginine/lysine/ornithine porter activity','F','OBSOLETE. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).','2013-10-27','NSRP'),(9809,15598,'arginine-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arginine(out) -> ADP + phosphate + arginine(in).','2013-10-27','NSRP'),(9810,15599,'glutamine-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).','2013-10-27','NSRP'),(9811,15600,'glutamate/aspartate porter activity','F','OBSOLETE. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).','2013-10-27','NSRP'),(9812,15601,'cystine/diaminopimelate porter activity','F','OBSOLETE. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).','2013-10-27','NSRP'),(9813,15602,'leucine/isoleucine/valine porter activity','F','OBSOLETE. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).','2013-10-27','NSRP'),(9814,15603,'iron chelate transmembrane transporter activity','F','Catalysis of the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.','2013-10-27','NSRP'),(9815,15604,'organic phosphonate transmembrane transporter activity','F','Catalysis of the transfer of phosphonate from one side of a membrane to the other. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).','2013-10-27','NSRP'),(9816,15605,'organophosphate ester transmembrane transporter activity','F','Catalysis of the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.','2013-10-27','NSRP'),(9817,15606,'spermidine transmembrane transporter activity','F','Catalysis of the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of the membrane to the other.','2013-10-27','NSRP'),(9818,15607,'fatty-acyl-CoA transporter activity','F','Enables the directed movement of a fatty acyl CoA group into, out of or within a cell, or between cells. A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.','2013-10-27','NSRP'),(9819,15608,'carbohydrate-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).','2013-10-27','NSRP'),(9820,15609,'maltooligosaccharide-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltooligosaccharide(out) -> ADP + phosphate + maltooligosaccharide(in).','2013-10-27','NSRP'),(9821,15610,'glycerol phosphate-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-phosphate(out) -> ADP + phosphate + glycerol-phosphate(in).','2013-10-27','NSRP'),(9822,15611,'D-ribose-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).','2013-10-27','NSRP'),(9823,15612,'L-arabinose-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in).','2013-10-27','NSRP'),(9824,15613,'galactose/glucose (methylgalactoside) porter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9825,15614,'D-xylose-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).','2013-10-27','NSRP'),(9826,15615,'D-allose-importing ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).','2013-10-27','NSRP'),(9827,15616,'DNA translocase activity','F','Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule.','2013-10-27','NSRP'),(9828,15617,'pilin/fimbrilin exporter activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9829,15619,'thiamine pyrophosphate-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine pyrophosphate(out) = ADP + phosphate + thiamine pyrophosphate(in).','2013-10-27','NSRP'),(9830,15620,'ferric-enterobactin transmembrane transporter activity','F','Catalysis of the transfer of ferric-enterobactin from one side of a membrane to the other.','2013-10-27','NSRP'),(9831,15621,'ferric triacetylfusarinine C transmembrane transporter activity','F','Catalysis of the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.','2013-10-27','NSRP'),(9832,15622,'ferric-hydroxamate transmembrane transporter activity','F','Catalysis of the transfer of ferric-hydroxamate from one side of a membrane to the other.','2013-10-27','NSRP'),(9833,15623,'iron-chelate-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + iron chelate(out) = ADP + phosphate + iron chelate(in). Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores are imported.','2013-10-27','NSRP'),(9834,15624,'ferric-enterobactin-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).','2013-10-27','NSRP'),(9835,15625,'ferric-hydroxamate-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).','2013-10-27','NSRP'),(9836,15626,'L-diaminopimelate transmembrane transporter activity','F','Catalysis of the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.','2013-10-27','NSRP'),(9837,15627,'type II protein secretion system complex','C','A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.','2013-10-27','NSRP'),(9838,15628,'protein secretion by the type II secretion system','P','The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.','2013-10-27','NSRP'),(9839,15629,'actin cytoskeleton','C','The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.','2013-10-27','NSRP'),(9840,15630,'microtubule cytoskeleton','C','The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.','2013-10-27','NSRP'),(9841,15631,'tubulin binding','F','Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.','2013-10-27','NSRP'),(9842,15633,'zinc transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).','2013-10-27','NSRP'),(9843,15634,'lipopolysaccharide exporter activity','F','Catalysis of the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.','2013-10-27','NSRP'),(9844,15635,'short-chain fatty acid transporter activity','F','Enables the directed movement of short-chain fatty acids into, out of or within a cell, or between cells. Short-chain fatty acids are fatty acids with a chain length of less than C6.','2013-10-27','NSRP'),(9845,15636,'short-chain fatty acid uptake transporter activity','F','Enables the directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.','2013-10-27','NSRP'),(9846,15638,'microcin uptake transporter activity','F','Catalysis of the transfer of a microcin from the outside of a cell to the inside of the cell across a membrane.','2013-10-27','NSRP'),(9847,15639,'ferrous iron uptake transmembrane transporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) + energy = Fe2+(in).','2013-10-27','NSRP'),(9848,15640,'peptidoglycan peptide transporter activity','F','Enables the directed movement of peptidoglycan peptides into, out of or within a cell, or between cells. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.','2013-10-27','NSRP'),(9849,15641,'lipoprotein toxin','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(9850,15642,'bacteriolytic toxin activity','F','OBSOLETE. Acts as to cause lysis of bacterial cells.','2013-10-27','NSRP'),(9851,15643,'toxic substance binding','F','Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.','2013-10-27','NSRP'),(9852,15644,'lipoprotein antitoxin','F','OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it.','2013-10-27','NSRP'),(9853,15645,'fatty acid ligase activity','F','Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.','2013-10-27','NSRP'),(9854,15647,'peptidoglycan transporter activity','F','Enables the directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9855,15648,'lipid-linked peptidoglycan transporter activity','F','Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(9856,15649,'2-keto-3-deoxygluconate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).','2013-10-27','NSRP'),(9857,15650,'lactate:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).','2013-10-27','NSRP'),(9858,15651,'quaternary ammonium group transmembrane transporter activity','F','Catalysis of the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.','2013-10-27','NSRP'),(9859,15652,'quaternary ammonium group:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).','2013-10-27','NSRP'),(9860,15653,'glycine betaine:hydrogen symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).','2013-10-27','NSRP'),(9861,15654,'tellurite uptake transmembrane transporter activity','F','Catalysis of the transfer of tellurite from the outside of a cell to the inside across a membrane: tellurite(out) + H+(out) = tellurite(in) + H+(in).','2013-10-27','NSRP'),(9862,15655,'alanine:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).','2013-10-27','NSRP'),(9863,15657,'branched-chain amino acid:sodium symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).','2013-10-27','NSRP'),(9864,15658,'branched-chain amino acid transmembrane transporter activity','F','Catalysis of the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.','2013-10-27','NSRP'),(9865,15659,'formate uptake transmembrane transporter activity','F','Catalysis of the transfer of formate from the outside of a cell to the inside of the cell across a membrane.','2013-10-27','NSRP'),(9866,15660,'formate efflux transmembrane transporter activity','F','Catalysis of the transfer of formate from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(9867,15661,'L-lysine efflux transmembrane transporter activity','F','Catalysis of the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.','2013-10-27','NSRP'),(9868,15662,'ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.','2013-10-27','NSRP'),(9869,15663,'nicotinamide mononucleotide transmembrane transporter activity','F','Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.','2013-10-27','NSRP'),(9870,15665,'alcohol transmembrane transporter activity','F','Catalysis of the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.','2013-10-27','NSRP'),(9871,15666,'restriction endodeoxyribonuclease activity','F','Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.','2013-10-27','NSRP'),(9872,15667,'site-specific DNA-methyltransferase (cytosine-N4-specific) activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.','2013-10-27','NSRP'),(9873,15668,'Type III site-specific deoxyribonuclease activity','F','Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5\'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.','2013-10-27','NSRP'),(9874,15669,'gas transport','P','The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9875,15670,'carbon dioxide transport','P','The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9876,15671,'oxygen transport','P','The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9877,15672,'monovalent inorganic cation transport','P','The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.','2013-10-27','NSRP'),(9878,15673,'silver ion transport','P','The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9879,15675,'nickel cation transport','P','The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9880,15676,'vanadium ion transport','P','The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9881,15677,'copper ion import','P','The directed movement of copper ions into a cell or organelle.','2013-10-27','NSRP'),(9882,15678,'high-affinity copper ion transport','P','The directed, high-affinity movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(9883,15679,'plasma membrane copper ion transport','P','The directed movement of copper ions across the plasma membrane.','2013-10-27','NSRP'),(9884,15680,'intracellular copper ion transport','P','The directed movement of copper (Cu) ions within a cell.','2013-10-27','NSRP'),(9885,15682,'ferric iron transport','P','The directed movement of ferric iron (Fe(III) or Fe3+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9886,15683,'high-affinity ferric iron transport','P','The directed, high-affinity movement of ferric (Fe(III) or Fe3+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.','2013-10-27','NSRP'),(9887,15684,'ferrous iron transport','P','The directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9888,15685,'ferric-enterobactin transport','P','The directed movement of ferric-enterobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9889,15686,'ferric triacetylfusarinine C transport','P','The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9890,15687,'ferric-hydroxamate transport','P','The directed movement of ferric-hydroxamate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9891,15688,'iron chelate transport','P','The directed movement of iron chelates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.','2013-10-27','NSRP'),(9892,15689,'molybdate ion transport','P','The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.','2013-10-27','NSRP'),(9893,15690,'aluminum cation transport','P','The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9894,15691,'cadmium ion transport','P','The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9895,15692,'lead ion transport','P','The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9896,15693,'magnesium ion transport','P','The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9897,15694,'mercury ion transport','P','The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9898,15695,'organic cation transport','P','The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.','2013-10-27','NSRP'),(9899,15696,'ammonium transport','P','The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.','2013-10-27','NSRP'),(9900,15697,'quaternary ammonium group transport','P','The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.','2013-10-27','NSRP'),(9901,15698,'inorganic anion transport','P','The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.','2013-10-27','NSRP'),(9902,15699,'antimonite transport','P','The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9903,15700,'arsenite transport','P','The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9904,15701,'bicarbonate transport','P','The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9905,15702,'chlorate transport','P','The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9906,15703,'chromate transport','P','The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9907,15704,'cyanate transport','P','The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9908,15705,'iodide transport','P','The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9909,15706,'nitrate transport','P','The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9910,15707,'nitrite transport','P','The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9911,15708,'silicate transport','P','The directed movement of silicates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.','2013-10-27','NSRP'),(9912,15709,'thiosulfate transport','P','The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9913,15710,'tellurite transport','P','The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9914,15711,'organic anion transport','P','The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.','2013-10-27','NSRP'),(9915,15712,'hexose phosphate transport','P','The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9916,15713,'phosphoglycerate transport','P','The directed movement of phosphoglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9917,15714,'phosphoenolpyruvate transport','P','The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9918,15715,'nucleotide-sulfate transport','P','The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9919,15716,'organic phosphonate transport','P','The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).','2013-10-27','NSRP'),(9920,15717,'triose phosphate transport','P','The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9921,15718,'monocarboxylic acid transport','P','The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9922,15719,'allantoate transport','P','The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9923,15720,'allantoin transport','P','The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9924,15721,'bile acid and bile salt transport','P','The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9925,15722,'canalicular bile acid transport','P','Catalysis of the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.','2013-10-27','NSRP'),(9926,15723,'bilirubin transport','P','The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9927,15724,'formate transport','P','The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9928,15725,'gluconate transport','P','The directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Gluconate is the aldonic acid derived from glucose.','2013-10-27','NSRP'),(9929,15726,'L-idonate transport','P','The directed movement of L-idonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.','2013-10-27','NSRP'),(9930,15727,'lactate transport','P','The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.','2013-10-27','NSRP'),(9931,15728,'mevalonate transport','P','The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9932,15729,'oxaloacetate transport','P','The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9933,15730,'propanoate transport','P','The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9934,15731,'3-hydroxyphenyl propanoate transport','P','The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9935,15732,'prostaglandin transport','P','The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9936,15733,'shikimate transport','P','The directed movement of shikimate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9937,15734,'taurine transport','P','The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9938,15735,'uronic acid transport','P','The directed movement of uronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9939,15736,'hexuronate transport','P','The directed movement of hexuronate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.','2013-10-27','NSRP'),(9940,15737,'galacturonate transport','P','The directed movement of galacturonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9941,15738,'glucuronate transport','P','The directed movement of glucuronate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9942,15739,'sialic acid transport','P','The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9943,15740,'C4-dicarboxylate transport','P','The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.','2013-10-27','NSRP'),(9944,15741,'fumarate transport','P','The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9945,15742,'alpha-ketoglutarate transport','P','The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9946,15743,'malate transport','P','The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9947,15744,'succinate transport','P','The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9948,15745,'tartrate transport','P','The directed movement of tartrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9949,15746,'citrate transport','P','The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9950,15747,'urate transport','P','The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9951,15748,'organophosphate ester transport','P','The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.','2013-10-27','NSRP'),(9952,15749,'monosaccharide transport','P','The directed movement of monosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.','2013-10-27','NSRP'),(9953,15750,'pentose transport','P','The directed movement of pentoses into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A pentose is any aldose with a chain of five carbon atoms in the molecule.','2013-10-27','NSRP'),(9954,15751,'arabinose transport','P','The directed movement of arabinose, a pentose monosaccharide that occurs in both D and L configurations, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9955,15752,'D-ribose transport','P','The directed movement of D-ribose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.','2013-10-27','NSRP'),(9956,15753,'D-xylose transport','P','The directed movement of D-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.','2013-10-27','NSRP'),(9957,15754,'allose transport','P','The directed movement of allose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.','2013-10-27','NSRP'),(9958,15755,'fructose transport','P','The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.','2013-10-27','NSRP'),(9959,15756,'fucose transport','P','The directed movement of fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.','2013-10-27','NSRP'),(9960,15757,'galactose transport','P','The directed movement of galactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.','2013-10-27','NSRP'),(9961,15758,'glucose transport','P','The directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9962,15759,'beta-glucoside transport','P','The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.','2013-10-27','NSRP'),(9963,15760,'glucose-6-phosphate transport','P','The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.','2013-10-27','NSRP'),(9964,15761,'mannose transport','P','The directed movement of mannose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.','2013-10-27','NSRP'),(9965,15762,'rhamnose transport','P','The directed movement of rhamnose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.','2013-10-27','NSRP'),(9966,15763,'N-acetylgalactosamine transport','P','The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.','2013-10-27','NSRP'),(9967,15764,'N-acetylglucosamine transport','P','The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9968,15765,'methylgalactoside transport','P','The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.','2013-10-27','NSRP'),(9969,15766,'disaccharide transport','P','The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.','2013-10-27','NSRP'),(9970,15767,'lactose transport','P','The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.','2013-10-27','NSRP'),(9971,15768,'maltose transport','P','The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.','2013-10-27','NSRP'),(9972,15769,'melibiose transport','P','The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.','2013-10-27','NSRP'),(9973,15770,'sucrose transport','P','The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.','2013-10-27','NSRP'),(9974,15771,'trehalose transport','P','The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.','2013-10-27','NSRP'),(9975,15772,'oligosaccharide transport','P','The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.','2013-10-27','NSRP'),(9976,15773,'raffinose transport','P','The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.','2013-10-27','NSRP'),(9977,15774,'polysaccharide transport','P','The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.','2013-10-27','NSRP'),(9978,15775,'beta-glucan transport','P','The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.','2013-10-27','NSRP'),(9979,15776,'capsular polysaccharide transport','P','The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.','2013-10-27','NSRP'),(9980,15777,'teichoic acid transport','P','The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.','2013-10-27','NSRP'),(9981,15778,'hexuronide transport','P','The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.','2013-10-27','NSRP'),(9982,15779,'glucuronoside transport','P','The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.','2013-10-27','NSRP'),(9983,15780,'nucleotide-sugar transport','P','The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5\'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.','2013-10-27','NSRP'),(9984,15781,'pyrimidine nucleotide-sugar transport','P','The directed movement of pyrimidine nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.','2013-10-27','NSRP'),(9985,15782,'CMP-N-acetylneuraminate transport','P','The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9986,15783,'GDP-fucose transport','P','The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.','2013-10-27','NSRP'),(9987,15784,'GDP-mannose transport','P','The directed movement of GDP-mannose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.','2013-10-27','NSRP'),(9988,15785,'UDP-galactose transport','P','The directed movement of UDP-galactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9989,15786,'UDP-glucose transport','P','The directed movement of UDP-glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9990,15787,'UDP-glucuronic acid transport','P','The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9991,15788,'UDP-N-acetylglucosamine transport','P','The directed movement of UDP-N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9992,15789,'UDP-N-acetylgalactosamine transport','P','The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9993,15790,'UDP-xylose transport','P','The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.','2013-10-27','NSRP'),(9994,15791,'polyol transport','P','The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(9995,15792,'arabinitol transport','P','The directed movement of arabitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.','2013-10-27','NSRP'),(9996,15793,'glycerol transport','P','The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.','2013-10-27','NSRP'),(9997,15794,'glycerol-3-phosphate transport','P','The directed movement of glycerol-3-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol-3-phosphate is a phosphoric monoester of glycerol.','2013-10-27','NSRP'),(9998,15795,'sorbitol transport','P','The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.','2013-10-27','NSRP'),(9999,15796,'galactitol transport','P','The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.','2013-10-27','NSRP'),(10000,15797,'mannitol transport','P','The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.','2013-10-27','NSRP'),(10001,15798,'myo-inositol transport','P','The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.','2013-10-27','NSRP'),(10002,15799,'propanediol transport','P','The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.','2013-10-27','NSRP'),(10003,15800,'acidic amino acid transport','P','The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10004,15801,'aromatic amino acid transport','P','The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10005,15802,'basic amino acid transport','P','The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10006,15803,'branched-chain amino acid transport','P','The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.','2013-10-27','NSRP'),(10007,15804,'neutral amino acid transport','P','The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10008,15805,'S-adenosyl-L-methionine transport','P','The directed movement of S-adenosylmethionine, S-(5\'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10009,15806,'S-methylmethionine transport','P','The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10010,15807,'L-amino acid transport','P','The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10011,15808,'L-alanine transport','P','The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10012,15809,'arginine transport','P','The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10013,15810,'aspartate transport','P','The directed movement of aspartate, the anion of aspartic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10014,15811,'L-cystine transport','P','The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10015,15812,'gamma-aminobutyric acid transport','P','The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10016,15813,'L-glutamate transport','P','The directed movement of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10017,15814,'p-aminobenzoyl-glutamate transport','P','The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10018,15816,'glycine transport','P','The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10019,15817,'histidine transport','P','The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10020,15818,'isoleucine transport','P','The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10021,15819,'lysine transport','P','The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10022,15820,'leucine transport','P','The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10023,15821,'methionine transport','P','The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10024,15822,'ornithine transport','P','The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10025,15823,'phenylalanine transport','P','The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10026,15824,'proline transport','P','The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10027,15825,'L-serine transport','P','The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10028,15826,'threonine transport','P','The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10029,15827,'tryptophan transport','P','The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10030,15828,'tyrosine transport','P','The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10031,15829,'valine transport','P','The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10032,15830,'diaminopimelate transport','P','The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10033,15832,'holin','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10034,15833,'peptide transport','P','The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10035,15834,'peptidoglycan-associated peptide transport','P','The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.','2013-10-27','NSRP'),(10036,15835,'peptidoglycan transport','P','The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10037,15836,'lipid-linked peptidoglycan transport','P','The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10038,15837,'amine transport','P','The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10039,15838,'amino-acid betaine transport','P','The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10040,15839,'cadaverine transport','P','The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10041,15840,'urea transport','P','The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.','2013-10-27','NSRP'),(10042,15841,'chromaffin granule amine transport','P','The directed movement of amines into, out of or within chromaffin granules.','2013-10-27','NSRP'),(10043,15842,'synaptic vesicle amine transport','P','The directed movement of amines into, out of or within synaptic vesicles.','2013-10-27','NSRP'),(10044,15843,'methylammonium transport','P','The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10045,15844,'monoamine transport','P','The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10046,15846,'polyamine transport','P','The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10047,15847,'putrescine transport','P','The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.','2013-10-27','NSRP'),(10048,15848,'spermidine transport','P','The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10049,15849,'organic acid transport','P','The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10050,15850,'organic hydroxy compound transport','P','The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.','2013-10-27','NSRP'),(10051,15851,'nucleobase transport','P','The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10052,15853,'adenine transport','P','The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10053,15854,'guanine transport','P','The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10054,15855,'pyrimidine nucleobase transport','P','The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10055,15856,'cytosine transport','P','The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10056,15857,'uracil transport','P','The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10057,15858,'nucleoside transport','P','The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10058,15859,'intracellular nucleoside transport','P','The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.','2013-10-27','NSRP'),(10059,15860,'purine nucleoside transmembrane transport','P','The directed movement of a purine nucleoside across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.','2013-10-27','NSRP'),(10060,15861,'cytidine transport','P','The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10061,15862,'uridine transport','P','The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10062,15863,'xanthosine transport','P','The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10063,15864,'pyrimidine nucleoside transport','P','The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10064,15865,'purine nucleotide transport','P','The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.','2013-10-27','NSRP'),(10065,15866,'ADP transport','P','The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10066,15867,'ATP transport','P','The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10067,15868,'purine ribonucleotide transport','P','The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.','2013-10-27','NSRP'),(10068,15869,'protein-DNA complex transport','P','The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10069,15870,'acetylcholine transport','P','The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.','2013-10-27','NSRP'),(10070,15871,'choline transport','P','The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.','2013-10-27','NSRP'),(10071,15872,'dopamine transport','P','The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.','2013-10-27','NSRP'),(10072,15874,'norepinephrine transport','P','The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.','2013-10-27','NSRP'),(10073,15875,'vitamin or cofactor transport','P','OBSOLETE. The directed movement of vitamins or cofactors into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(10074,15876,'acetyl-CoA transport','P','The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.','2013-10-27','NSRP'),(10075,15877,'biopterin transport','P','The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.','2013-10-27','NSRP'),(10076,15878,'biotin transport','P','The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.','2013-10-27','NSRP'),(10077,15879,'carnitine transport','P','The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.','2013-10-27','NSRP'),(10078,15880,'coenzyme A transport','P','The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.','2013-10-27','NSRP'),(10079,15881,'creatine transport','P','The directed movement of creatine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.','2013-10-27','NSRP'),(10080,15882,'L-ascorbic acid transport','P','The directed movement of L-ascorbic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.','2013-10-27','NSRP'),(10081,15883,'FAD transport','P','The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.','2013-10-27','NSRP'),(10082,15884,'folic acid transport','P','The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.','2013-10-27','NSRP'),(10083,15885,'5-formyltetrahydrofolate transport','P','The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10084,15886,'heme transport','P','The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10085,15887,'pantothenate transmembrane transport','P','The directed movement of pantothenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.','2013-10-27','NSRP'),(10086,15888,'thiamine transport','P','The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.','2013-10-27','NSRP'),(10087,15889,'cobalamin transport','P','The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10088,15890,'nicotinamide mononucleotide transport','P','The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.','2013-10-27','NSRP'),(10089,15891,'siderophore transport','P','The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10090,15893,'drug transport','P','The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10091,15894,'acriflavine transport','P','The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.','2013-10-27','NSRP'),(10092,15895,'alkane transport','P','The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.','2013-10-27','NSRP'),(10093,15896,'nalidixic acid transport','P','The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.','2013-10-27','NSRP'),(10094,15897,'organomercurial transport','P','The directed movement of organomercurial compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organomercurial substances are any organic compound containing a mercury atom.','2013-10-27','NSRP'),(10095,15898,'amiloride transport','P','The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.','2013-10-27','NSRP'),(10096,15899,'aminotriazole transport','P','The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.','2013-10-27','NSRP'),(10097,15900,'benomyl transport','P','The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.','2013-10-27','NSRP'),(10098,15901,'cycloheximide transport','P','The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.','2013-10-27','NSRP'),(10099,15902,'carbonyl cyanide m-chlorophenylhydrazone transport','P','The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.','2013-10-27','NSRP'),(10100,15903,'fluconazole transport','P','The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.','2013-10-27','NSRP'),(10101,15904,'tetracycline transport','P','The directed movement of tetracycline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).','2013-10-27','NSRP'),(10102,15905,'bicyclomycin transport','P','The directed movement of bicyclomycin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.','2013-10-27','NSRP'),(10103,15906,'sulfathiazole transport','P','The directed movement of sulfathiazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sulfathiazole is an antibacterial agent of the sulfonamide group.','2013-10-27','NSRP'),(10104,15908,'fatty acid transport','P','The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.','2013-10-27','NSRP'),(10105,15909,'long-chain fatty acid transport','P','The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(10106,15910,'peroxisomal long-chain fatty acid import','P','The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(10107,15911,'plasma membrane long-chain fatty acid transport','P','The directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(10108,15912,'short-chain fatty acid transport','P','The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6.','2013-10-27','NSRP'),(10109,15913,'short-chain fatty acid import','P','The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.','2013-10-27','NSRP'),(10110,15914,'phospholipid transport','P','The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.','2013-10-27','NSRP'),(10111,15915,'fatty-acyl group transport','P','The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid.','2013-10-27','NSRP'),(10112,15916,'fatty-acyl-CoA transport','P','The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine (coenzyme A).','2013-10-27','NSRP'),(10113,15917,'aminophospholipid transport','P','The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.','2013-10-27','NSRP'),(10114,15918,'sterol transport','P','The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.','2013-10-27','NSRP'),(10115,15919,'peroxisomal membrane transport','P','The directed movement of substances to, from or across the peroxisomal membrane.','2013-10-27','NSRP'),(10116,15920,'lipopolysaccharide transport','P','The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.','2013-10-27','NSRP'),(10117,15921,'lipopolysaccharide export','P','The directed movement of lipopolysaccharides out of a cell or organelle.','2013-10-27','NSRP'),(10118,15922,'aspartate oxidase activity','F','Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide.','2013-10-27','NSRP'),(10119,15923,'mannosidase activity','F','Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.','2013-10-27','NSRP'),(10120,15924,'mannosyl-oligosaccharide mannosidase activity','F','Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.','2013-10-27','NSRP'),(10121,15925,'galactosidase activity','F','Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.','2013-10-27','NSRP'),(10122,15926,'glucosidase activity','F','Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.','2013-10-27','NSRP'),(10123,15927,'trehalase activity','F','Catalysis of the hydrolysis of trehalose or a trehalose derivative.','2013-10-27','NSRP'),(10124,15928,'fucosidase activity','F','Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.','2013-10-27','NSRP'),(10125,15929,'hexosaminidase activity','F','Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.','2013-10-27','NSRP'),(10126,15930,'glutamate synthase activity','F','Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.','2013-10-27','NSRP'),(10127,15931,'nucleobase-containing compound transport','P','The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10128,15932,'nucleobase-containing compound transmembrane transporter activity','F','Catalysis of the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.','2013-10-27','NSRP'),(10129,15933,'flavin-containing electron transporter','F','OBSOLETE. An oxidoreductase which contains either flavin-adenine dinucleotide or flavin mononucleotide as a prosthetic group, utilizes either NADH or NADPH and transfers electrons to other electron transfer proteins.','2013-10-27','NSRP'),(10130,15934,'large ribosomal subunit','C','The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).','2013-10-27','NSRP'),(10131,15935,'small ribosomal subunit','C','The smaller of the two subunits of a ribosome.','2013-10-27','NSRP'),(10132,15936,'coenzyme A metabolic process','P','The chemical reactions and pathways involving coenzyme A, 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.','2013-10-27','NSRP'),(10133,15937,'coenzyme A biosynthetic process','P','The chemical reactions and pathways resulting in the formation of coenzyme A, 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.','2013-10-27','NSRP'),(10134,15938,'coenzyme A catabolic process','P','The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3\'-phosphoadenosine-(5\')diphospho(4\')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.','2013-10-27','NSRP'),(10135,15939,'pantothenate metabolic process','P','The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.','2013-10-27','NSRP'),(10136,15940,'pantothenate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.','2013-10-27','NSRP'),(10137,15941,'pantothenate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.','2013-10-27','NSRP'),(10138,15942,'formate metabolic process','P','The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.','2013-10-27','NSRP'),(10139,15943,'formate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.','2013-10-27','NSRP'),(10140,15944,'formate oxidation','P','The chemical reactions and pathways by which formate is converted to CO2.','2013-10-27','NSRP'),(10141,15945,'methanol metabolic process','P','The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.','2013-10-27','NSRP'),(10142,15946,'methanol oxidation','P','The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.','2013-10-27','NSRP'),(10143,15947,'methane metabolic process','P','The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.','2013-10-27','NSRP'),(10144,15948,'methanogenesis','P','The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.','2013-10-27','NSRP'),(10145,15949,'nucleobase-containing small molecule interconversion','P','The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.','2013-10-27','NSRP'),(10146,15950,'purine nucleotide interconversion','P','The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.','2013-10-27','NSRP'),(10147,15951,'purine ribonucleotide interconversion','P','The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.','2013-10-27','NSRP'),(10148,15952,'purine deoxyribonucleotide interconversion','P','The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.','2013-10-27','NSRP'),(10149,15953,'pyrimidine nucleotide interconversion','P','The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.','2013-10-27','NSRP'),(10150,15954,'pyrimidine ribonucleotide interconversion','P','The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.','2013-10-27','NSRP'),(10151,15955,'pyrimidine deoxyribonucleotide interconversion','P','The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.','2013-10-27','NSRP'),(10152,15956,'bis(5\'-nucleosidyl) oligophosphate metabolic process','P','The chemical reactions and pathways involving a bis(5\'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5\' carbons by a chain of phosphate molecules.','2013-10-27','NSRP'),(10153,15957,'bis(5\'-nucleosidyl) oligophosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a bis(5\'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5\' carbons by a chain of phosphate molecules.','2013-10-27','NSRP'),(10154,15958,'bis(5\'-nucleosidyl) oligophosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a bis(5\'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5\' carbons by a chain of phosphate molecules.','2013-10-27','NSRP'),(10155,15959,'diadenosine polyphosphate metabolic process','P','The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.','2013-10-27','NSRP'),(10156,15960,'diadenosine polyphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.','2013-10-27','NSRP'),(10157,15961,'diadenosine polyphosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.','2013-10-27','NSRP'),(10158,15962,'diadenosine triphosphate metabolic process','P','The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.','2013-10-27','NSRP'),(10159,15963,'diadenosine triphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.','2013-10-27','NSRP'),(10160,15964,'diadenosine triphosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.','2013-10-27','NSRP'),(10161,15965,'diadenosine tetraphosphate metabolic process','P','The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.','2013-10-27','NSRP'),(10162,15966,'diadenosine tetraphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.','2013-10-27','NSRP'),(10163,15967,'diadenosine tetraphosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.','2013-10-27','NSRP'),(10164,15968,'stringent response','P','A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.','2013-10-27','NSRP'),(10165,15969,'guanosine tetraphosphate metabolic process','P','The chemical reactions and pathways involving guanine tetraphosphate (5\'-ppGpp-3\'), a derivative of guanine riboside with four phosphates.','2013-10-27','NSRP'),(10166,15970,'guanosine tetraphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5\'-ppGpp-3\'), a derivative of guanine riboside with four phosphates.','2013-10-27','NSRP'),(10167,15971,'guanosine tetraphosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5\'-ppGpp-3\'), a derivative of guanine riboside with four phosphates.','2013-10-27','NSRP'),(10168,15972,'guanosine pentaphosphate metabolic process','P','The chemical reactions and pathways involving guanine pentaphosphate (5\'-pppGpp-3\'), a derivative of guanine riboside with five phosphates.','2013-10-27','NSRP'),(10169,15973,'guanosine pentaphosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5\'-pppGpp-3\'), a derivative of guanine riboside with five phosphates.','2013-10-27','NSRP'),(10170,15974,'guanosine pentaphosphate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5\'-pppGpp-3\'), a derivative of guanine riboside with five phosphates.','2013-10-27','NSRP'),(10171,15975,'energy derivation by oxidation of reduced inorganic compounds','P','The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.','2013-10-27','NSRP'),(10172,15976,'carbon utilization','P','A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism\'s metabolism.','2013-10-27','NSRP'),(10173,15977,'carbon fixation','P','A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).','2013-10-27','NSRP'),(10174,15979,'photosynthesis','P','The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.','2013-10-27','NSRP'),(10175,15980,'energy derivation by oxidation of organic compounds','P','The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.','2013-10-27','NSRP'),(10176,15981,'passive proton transport, down the electrochemical gradient','P','OBSOLETE. The passive movement of protons from areas of high proton concentration and electrical potential to areas where concentration and electrical potential are low.','2013-10-27','NSRP'),(10177,15982,'antiport','P','OBSOLETE. The process of coupled solute translocation in which two solutes equilibrate across an osmotic barrier, the translocation of solute being coupled to the translocation of the other in the opposite direction.','2013-10-27','NSRP'),(10178,15983,'symport','P','OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction.','2013-10-27','NSRP'),(10179,15984,'uniport','P','OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion.','2013-10-27','NSRP'),(10180,15985,'energy coupled proton transport, down electrochemical gradient','P','The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.','2013-10-27','NSRP'),(10181,15986,'ATP synthesis coupled proton transport','P','The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.','2013-10-27','NSRP'),(10182,15987,'GTP synthesis coupled proton transport','P','The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.','2013-10-27','NSRP'),(10183,15988,'energy coupled proton transmembrane transport, against electrochemical gradient','P','The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.','2013-10-27','NSRP'),(10184,15989,'light-driven proton transport','P','The transport of protons against an electrochemical gradient, using energy from light.','2013-10-27','NSRP'),(10185,15990,'electron transport coupled proton transport','P','The transport of protons against an electrochemical gradient, using energy from electron transport.','2013-10-27','NSRP'),(10186,15991,'ATP hydrolysis coupled proton transport','P','The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis.','2013-10-27','NSRP'),(10187,15992,'proton transport','P','The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10188,15993,'molecular hydrogen transport','P','The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(10189,15994,'chlorophyll metabolic process','P','The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.','2013-10-27','NSRP'),(10190,15995,'chlorophyll biosynthetic process','P','The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.','2013-10-27','NSRP'),(10191,15996,'chlorophyll catabolic process','P','The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.','2013-10-27','NSRP'),(10192,15997,'ubiquinone biosynthetic process monooxygenase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10193,16002,'sulfite reductase activity','F','Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.','2013-10-27','NSRP'),(10194,16004,'phospholipase activator activity','F','Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.','2013-10-27','NSRP'),(10195,16005,'phospholipase A2 activator activity','F','Increases the activity of the enzyme phospholipase A2.','2013-10-27','NSRP'),(10196,16006,'Nebenkern','C','A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.','2013-10-27','NSRP'),(10197,16007,'mitochondrial derivative','C','The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.','2013-10-27','NSRP'),(10198,16008,'major mitochondrial derivative','C','The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.','2013-10-27','NSRP'),(10199,16009,'minor mitochondrial derivative','C','The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.','2013-10-27','NSRP'),(10200,16010,'dystrophin-associated glycoprotein complex','C','A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.','2013-10-27','NSRP'),(10201,16011,'dystroglycan complex','C','A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.','2013-10-27','NSRP'),(10202,16012,'sarcoglycan complex','C','A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.','2013-10-27','NSRP'),(10203,16013,'syntrophin complex','C','A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.','2013-10-27','NSRP'),(10204,16014,'dystrobrevin complex','C','A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.','2013-10-27','NSRP'),(10205,16015,'morphogen activity','F','Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.','2013-10-27','NSRP'),(10206,16016,'short-wave-sensitive opsin','F','OBSOLETE. An opsin with maximal absorption between 400 and 500 nm.','2013-10-27','NSRP'),(10207,16018,'cyclosporin A binding','F','Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.','2013-10-27','NSRP'),(10208,16019,'peptidoglycan receptor activity','F','Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.','2013-10-27','NSRP'),(10209,16020,'membrane','C','Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.','2013-10-27','NSRP'),(10210,16021,'integral to membrane','C','Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.','2013-10-27','NSRP'),(10211,16023,'cytoplasmic membrane-bounded vesicle','C','A membrane-bounded vesicle found in the cytoplasm of the cell.','2013-10-27','NSRP'),(10212,16024,'CDP-diacylglycerol biosynthetic process','P','The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.','2013-10-27','NSRP'),(10213,16025,'proteasome endopeptidase regulator','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10214,16026,'proteasome endopeptidase core','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10215,16027,'inaD signaling complex','C','A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.','2013-10-27','NSRP'),(10216,16028,'rhabdomere','C','The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.','2013-10-27','NSRP'),(10217,16029,'subrhabdomeral cisterna','C','A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.','2013-10-27','NSRP'),(10218,16030,'metarhodopsin binding','F','Interacting selectively and non-covalently with metarhodopsin, a transient intermediate produced upon irradiation of rhodopsin in the visual cycle and existing in two forms, metarhodopsins I and II. The latter dissociates to form opsin and all-trans retinal.','2012-03-14','NSRP'),(10219,16031,'tRNA import into mitochondrion','P','The directed movement of tRNA, transfer ribonucleic acid, from the cytoplasm into a mitochondrion.','2013-10-27','NSRP'),(10220,16032,'viral process','P','A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, \'complete\' its life cycle.','2013-10-27','NSRP'),(10221,16034,'maleylacetoacetate isomerase activity','F','Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.','2013-10-27','NSRP'),(10222,16035,'zeta DNA polymerase complex','C','A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.','2013-10-27','NSRP'),(10223,16036,'cellular response to phosphate starvation','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.','2013-10-27','NSRP'),(10224,16037,'light absorption','P','The reception of a photon by a cell.','2013-10-27','NSRP'),(10225,16038,'absorption of visible light','P','The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.','2013-10-27','NSRP'),(10226,16039,'absorption of UV light','P','The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.','2013-10-27','NSRP'),(10227,16040,'glutamate synthase (NADH) activity','F','Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH.','2013-10-27','NSRP'),(10228,16041,'glutamate synthase (ferredoxin) activity','F','Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.','2013-10-27','NSRP'),(10229,16042,'lipid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.','2013-10-27','NSRP'),(10230,16043,'cellular component organization','P','A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.','2013-10-27','NSRP'),(10231,16044,'cellular membrane organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.','2013-09-08','NSRP'),(10232,16045,'detection of bacterium','P','The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.','2013-10-27','NSRP'),(10233,16046,'detection of fungus','P','The series of events in which a stimulus from a fungus is received and converted into a molecular signal.','2013-10-27','NSRP'),(10234,16047,'detection of parasitic fungus','P','The series of events in which a stimulus from a parasitic fungus (a fungus which spends all or part of its life in or on another organism from which it obtains nourishment and/or protection) is received and converted into a molecular signal.','2013-10-27','NSRP'),(10235,16048,'detection of temperature stimulus','P','The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.','2013-10-27','NSRP'),(10236,16049,'cell growth','P','The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.','2013-10-27','NSRP'),(10237,16050,'vesicle organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.','2013-10-27','NSRP'),(10238,16051,'carbohydrate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.','2013-10-27','NSRP'),(10239,16052,'carbohydrate catabolic process','P','The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.','2013-10-27','NSRP'),(10240,16053,'organic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.','2013-10-27','NSRP'),(10241,16054,'organic acid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.','2013-10-27','NSRP'),(10242,16055,'Wnt receptor signaling pathway','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.','2013-10-27','NSRP'),(10243,16056,'rhodopsin mediated signaling pathway','P','The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.','2013-10-27','NSRP'),(10244,16057,'regulation of membrane potential in photoreceptor cell','P','Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.','2013-10-27','NSRP'),(10245,16058,'maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling','P','Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.','2013-10-27','NSRP'),(10246,16059,'deactivation of rhodopsin mediated signaling','P','The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).','2013-10-27','NSRP'),(10247,16060,'metarhodopsin inactivation','P','The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.','2013-10-27','NSRP'),(10248,16061,'regulation of light-activated channel activity','P','Any process that modulates the frequency, rate or extent of light-activated channel activity.','2013-10-27','NSRP'),(10249,16062,'adaptation of rhodopsin mediated signaling','P','The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.','2013-10-27','NSRP'),(10250,16063,'rhodopsin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.','2013-10-27','NSRP'),(10251,16064,'immunoglobulin mediated immune response','P','An immune response mediated by immunoglobulins, whether cell-bound or in solution.','2013-10-27','NSRP'),(10252,16065,'humoral defense mechanism (sensu Protostomia)','P','OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).','2013-10-27','NSRP'),(10253,16068,'type I hypersensitivity','P','An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.','2013-10-27','NSRP'),(10254,16070,'RNA metabolic process','P','The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3\',5\'-phosphodiester linkage.','2013-10-27','NSRP'),(10255,16071,'mRNA metabolic process','P','The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic \'message\', transcribed from DNA, to sites of protein assembly at the ribosomes.','2013-10-27','NSRP'),(10256,16072,'rRNA metabolic process','P','The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.','2013-10-27','NSRP'),(10257,16073,'snRNA metabolic process','P','The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.','2013-10-27','NSRP'),(10258,16074,'snoRNA metabolic process','P','The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.','2013-10-27','NSRP'),(10259,16075,'rRNA catabolic process','P','The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.','2013-10-27','NSRP'),(10260,16076,'snRNA catabolic process','P','The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.','2013-10-27','NSRP'),(10261,16077,'snoRNA catabolic process','P','The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.','2013-10-27','NSRP'),(10262,16078,'tRNA catabolic process','P','The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.','2013-10-27','NSRP'),(10263,16079,'synaptic vesicle exocytosis','P','Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.','2013-10-27','NSRP'),(10264,16080,'synaptic vesicle targeting','P','The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.','2013-10-27','NSRP'),(10265,16081,'synaptic vesicle docking involved in exocytosis','P','The initial attachment of a synaptic vesicle membrane to the presynaptic membrane, mediated by proteins protruding from the membrane of the synaptic vesicle and the target membrane.','2013-10-27','NSRP'),(10266,16082,'synaptic vesicle priming','P','The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.','2013-10-27','NSRP'),(10267,16083,'synaptic vesicle fusion','P','OBSOLETE. Fusion of the synaptic vesicle with the postsynaptic membrane.','2013-10-27','NSRP'),(10268,16084,'myostimulatory hormone activity','F','The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.','2013-10-27','NSRP'),(10269,16085,'myoinhibitory hormone activity','F','The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.','2013-10-27','NSRP'),(10270,16086,'allatostatin','F','OBSOLETE. Peptide hormones produced by the corpora allata of insects that reversibly inhibit the production of juvenile hormone.','2013-10-27','NSRP'),(10271,16087,'ecdysiostatic hormone activity','F','The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.','2013-10-27','NSRP'),(10272,16088,'insulin','F','OBSOLETE. A polypeptide hormone that stimulates glucose uptake by muscle and adipose tissue, and promotes glycogenesis, lipogenesis and the synthesis of proteins and nucleic acids.','2013-10-27','NSRP'),(10273,16090,'prenol metabolic process','P','The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.','2013-10-27','NSRP'),(10274,16091,'prenol biosynthetic process','P','The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.','2013-10-27','NSRP'),(10275,16092,'prenol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.','2013-10-27','NSRP'),(10276,16093,'polyprenol metabolic process','P','The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.','2013-10-27','NSRP'),(10277,16094,'polyprenol biosynthetic process','P','The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.','2013-10-27','NSRP'),(10278,16095,'polyprenol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.','2013-10-27','NSRP'),(10279,16098,'monoterpenoid metabolic process','P','The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.','2013-10-27','NSRP'),(10280,16099,'monoterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.','2013-10-27','NSRP'),(10281,16100,'monoterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.','2013-10-27','NSRP'),(10282,16101,'diterpenoid metabolic process','P','The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.','2013-10-27','NSRP'),(10283,16102,'diterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.','2013-10-27','NSRP'),(10284,16103,'diterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.','2013-10-27','NSRP'),(10285,16104,'triterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.','2013-10-27','NSRP'),(10286,16105,'triterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.','2013-10-27','NSRP'),(10287,16106,'sesquiterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.','2013-10-27','NSRP'),(10288,16107,'sesquiterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.','2013-10-27','NSRP'),(10289,16108,'tetraterpenoid metabolic process','P','The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.','2013-10-27','NSRP'),(10290,16109,'tetraterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.','2013-10-27','NSRP'),(10291,16110,'tetraterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.','2013-10-27','NSRP'),(10292,16111,'polyterpenoid metabolic process','P','The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units.','2013-10-27','NSRP'),(10293,16112,'polyterpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.','2013-10-27','NSRP'),(10294,16113,'polyterpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.','2013-10-27','NSRP'),(10295,16114,'terpenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.','2013-10-27','NSRP'),(10296,16115,'terpenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.','2013-10-27','NSRP'),(10297,16116,'carotenoid metabolic process','P','The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.','2013-10-27','NSRP'),(10298,16117,'carotenoid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.','2013-10-27','NSRP'),(10299,16118,'carotenoid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.','2013-10-27','NSRP'),(10300,16119,'carotene metabolic process','P','The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.','2013-10-27','NSRP'),(10301,16120,'carotene biosynthetic process','P','The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.','2013-10-27','NSRP'),(10302,16121,'carotene catabolic process','P','The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.','2013-10-27','NSRP'),(10303,16122,'xanthophyll metabolic process','P','The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.','2013-10-27','NSRP'),(10304,16123,'xanthophyll biosynthetic process','P','The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.','2013-10-27','NSRP'),(10305,16124,'xanthophyll catabolic process','P','The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.','2013-10-27','NSRP'),(10306,16125,'sterol metabolic process','P','The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.','2013-10-27','NSRP'),(10307,16126,'sterol biosynthetic process','P','The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.','2013-10-27','NSRP'),(10308,16127,'sterol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.','2013-10-27','NSRP'),(10309,16128,'phytosteroid metabolic process','P','The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.','2013-10-27','NSRP'),(10310,16129,'phytosteroid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.','2013-10-27','NSRP'),(10311,16130,'phytosteroid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.','2013-10-27','NSRP'),(10312,16131,'brassinosteroid metabolic process','P','The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.','2013-10-27','NSRP'),(10313,16132,'brassinosteroid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.','2013-10-27','NSRP'),(10314,16133,'brassinosteroid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.','2013-10-27','NSRP'),(10315,16134,'saponin metabolic process','P','The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.','2013-10-27','NSRP'),(10316,16135,'saponin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.','2013-10-27','NSRP'),(10317,16136,'saponin catabolic process','P','The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.','2013-10-27','NSRP'),(10318,16137,'glycoside metabolic process','P','The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.','2013-10-27','NSRP'),(10319,16138,'glycoside biosynthetic process','P','The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.','2013-10-27','NSRP'),(10320,16139,'glycoside catabolic process','P','The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.','2013-10-27','NSRP'),(10321,16140,'O-glycoside metabolic process','P','The chemical reactions and pathways involving O-glycosides, any compound in which a glycosyl group has been substituted into a hydroxyl group.','2012-03-14','NSRP'),(10322,16141,'O-glycoside biosynthetic process','P','The chemical reactions and pathways resulting in the formation of O-glycosides, any compound in which a glycosyl group has been substituted into a hydroxyl group.','2012-03-14','NSRP'),(10323,16142,'O-glycoside catabolic process','P','The chemical reactions and pathways resulting in the breakdown of O-glycosides, any compound in which a glycosyl group has been substituted into a hydroxyl group.','2012-03-14','NSRP'),(10324,16143,'S-glycoside metabolic process','P','The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.','2013-10-27','NSRP'),(10325,16144,'S-glycoside biosynthetic process','P','The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.','2013-10-27','NSRP'),(10326,16145,'S-glycoside catabolic process','P','The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.','2013-10-27','NSRP'),(10327,16146,'protein-synthesizing GTPase activity, initiation','F','OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.','2013-10-27','NSRP'),(10328,16147,'protein-synthesizing GTPase activity, elongation','F','OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.','2013-10-27','NSRP'),(10329,16148,'protein-synthesizing GTPase activity, termination','F','OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate.','2013-10-27','NSRP'),(10330,16149,'translation release factor activity, codon specific','F','A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.','2013-10-27','NSRP'),(10331,16150,'translation release factor activity, codon nonspecific','F','A translation release factor that is not specific to particular codons; binds to guanine nucleotides.','2013-10-27','NSRP'),(10332,16151,'nickel cation binding','F','Interacting selectively and non-covalently with nickel (Ni) cations.','2013-10-27','NSRP'),(10333,16152,'mercury (II) reductase activity','F','Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH.','2013-10-27','NSRP'),(10334,16153,'urocanate hydratase activity','F','Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O.','2013-10-27','NSRP'),(10335,16154,'pyrimidine-nucleoside phosphorylase activity','F','Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.','2013-10-27','NSRP'),(10336,16155,'formyltetrahydrofolate dehydrogenase activity','F','Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH.','2013-10-27','NSRP'),(10337,16156,'fumarate reductase (NADH) activity','F','Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH.','2013-10-27','NSRP'),(10338,16157,'sucrose synthase activity','F','Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.','2013-10-27','NSRP'),(10339,16158,'3-phytase activity','F','Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.','2013-10-27','NSRP'),(10340,16159,'muconolactone delta-isomerase activity','F','Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate.','2013-10-27','NSRP'),(10341,16160,'amylase activity','F','Catalysis of the hydrolysis of amylose or an amylose derivative.','2013-10-27','NSRP'),(10342,16161,'beta-amylase activity','F','Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.','2013-10-27','NSRP'),(10343,16162,'cellulose 1,4-beta-cellobiosidase activity','F','Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.','2013-10-27','NSRP'),(10344,16163,'nitrogenase activity','F','Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.','2013-10-27','NSRP'),(10345,16164,'Mo-molybdopterin oxidoreductase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10346,16165,'linoleate 13S-lipoxygenase activity','F','Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.','2013-10-27','NSRP'),(10347,16166,'phytoene dehydrogenase activity','F','Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.','2013-10-27','NSRP'),(10348,16167,'glial cell-derived neurotrophic factor receptor activity','F','Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(10349,16168,'chlorophyll binding','F','Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.','2013-10-27','NSRP'),(10350,16169,'bacteriochlorophyll c binding','F','Interacting selectively and non-covalently with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.','2013-10-27','NSRP'),(10351,16170,'interleukin-15 receptor binding','F','Interacting selectively and non-covalently with the interleukin-15 receptor.','2013-10-27','NSRP'),(10352,16171,'cell surface antigen','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10353,16172,'antifreeze activity','F','OBSOLETE. Inhibits the formation of ice crystals in organismal fluid (e.g. blood) at below freezing exogenous temperatures.','2013-10-27','NSRP'),(10354,16173,'ice nucleation inhibitor activity','F','OBSOLETE. Inhibits the formation of ice crystals.','2013-10-27','NSRP'),(10355,16174,'NAD(P)H oxidase activity','F','Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.','2013-10-27','NSRP'),(10356,16175,'superoxide-generating NADPH oxidase activity','F','Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.','2013-10-27','NSRP'),(10357,16176,'superoxide-generating NADPH oxidase activator activity','F','Increases the activity of the enzyme superoxide-generating NADPH oxidase.','2013-10-27','NSRP'),(10358,16180,'snRNA processing','P','Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.','2013-10-27','NSRP'),(10359,16182,'synaptic vesicle budding from endosome','P','Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.','2013-10-27','NSRP'),(10360,16183,'synaptic vesicle coating','P','A protein coat is added to the synaptic vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.','2013-10-27','NSRP'),(10361,16184,'synaptic vesicle retrieval','P','OBSOLETE. Return of a vesicle from the postsynaptic membrane to presynaptic membrane.','2013-10-27','NSRP'),(10362,16185,'synaptic vesicle budding from presynaptic membrane','P','Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.','2013-10-27','NSRP'),(10363,16186,'synaptic vesicle fission','P','OBSOLETE. Separation of a synaptic vesicle from the presynaptic membrane.','2013-10-27','NSRP'),(10364,16187,'synaptic vesicle internalization','P','OBSOLETE. Internalization of the contents of a synaptic vesicle into the postsynaptic membrane following endocytosis.','2013-10-27','NSRP'),(10365,16188,'synaptic vesicle maturation','P','Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.','2013-10-27','NSRP'),(10366,16189,'synaptic vesicle to endosome fusion','P','Fusion of a synaptic vesicle with the membrane of an endosome.','2013-10-27','NSRP'),(10367,16191,'synaptic vesicle uncoating','P','The removal of the protein coat on a synaptic vesicle.','2013-10-27','NSRP'),(10368,16192,'vesicle-mediated transport','P','A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.','2013-10-27','NSRP'),(10369,16197,'endosomal transport','P','The directed movement of substances into, out of or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.','2013-10-27','NSRP'),(10370,16198,'axon choice point recognition','P','The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.','2013-10-27','NSRP'),(10371,16199,'axon midline choice point recognition','P','The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.','2013-10-27','NSRP'),(10372,16200,'synaptic target attraction','P','The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.','2013-10-27','NSRP'),(10373,16201,'synaptic target inhibition','P','The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.','2013-10-27','NSRP'),(10374,16202,'regulation of striated muscle tissue development','P','Any process that modulates the frequency, rate or extent of striated muscle development.','2013-10-27','NSRP'),(10375,16203,'muscle attachment','P','The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).','2013-10-27','NSRP'),(10376,16204,'determination of muscle attachment site','P','The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.','2013-10-27','NSRP'),(10377,16205,'selenocysteine methyltransferase activity','F','Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.','2013-10-27','NSRP'),(10378,16206,'catechol O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.','2013-10-27','NSRP'),(10379,16207,'4-coumarate-CoA ligase activity','F','Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.','2013-10-27','NSRP'),(10380,16208,'AMP binding','F','Interacting selectively and non-covalently with AMP, adenosine monophosphate.','2013-10-27','NSRP'),(10381,16209,'antioxidant activity','F','Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.','2013-10-27','NSRP'),(10382,16210,'naringenin-chalcone synthase activity','F','Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.','2013-10-27','NSRP'),(10383,16211,'ammonia ligase activity','F','Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.','2013-10-27','NSRP'),(10384,16212,'kynurenine-oxoglutarate transaminase activity','F','Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.','2013-10-27','NSRP'),(10385,16213,'linoleoyl-CoA desaturase activity','F','Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.','2013-10-27','NSRP'),(10386,16215,'acyl-CoA desaturase activity','F','Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.','2013-10-27','NSRP'),(10387,16216,'isopenicillin-N synthase activity','F','Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N.','2013-10-27','NSRP'),(10388,16217,'N-ethylammeline chlorohydrolase activity','F','Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.','2013-10-27','NSRP'),(10389,16218,'polyketide synthase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10390,16222,'procollagen-proline 4-dioxygenase complex','C','A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.','2013-10-27','NSRP'),(10391,16223,'beta-alanine-pyruvate transaminase activity','F','Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.','2013-10-27','NSRP'),(10392,16226,'iron-sulfur cluster assembly','P','The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.','2013-10-27','NSRP'),(10393,16227,'tRNA sulfurtransferase activity','F','OBSOLETE. Catalysis of the reaction: L-cysteine + \'activated\' tRNA = L-serine + tRNA containing a thionucleotide.','2013-10-27','NSRP'),(10394,16229,'steroid dehydrogenase activity','F','Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.','2013-10-27','NSRP'),(10395,16230,'sphingomyelin phosphodiesterase activator activity','F','Increases the activity of the enzyme sphingomyelin phosphodiesterase.','2013-10-27','NSRP'),(10396,16231,'beta-N-acetylglucosaminidase activity','F','Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.','2013-10-27','NSRP'),(10397,16232,'HNK-1 sulfotransferase activity','F','Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).','2013-10-27','NSRP'),(10398,16233,'telomere capping','P','A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.','2013-10-27','NSRP'),(10399,16234,'inclusion body','C','A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.','2013-10-27','NSRP'),(10400,16235,'aggresome','C','An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.','2013-10-27','NSRP'),(10401,16236,'macroautophagy','P','The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane-bounded autophagic bodies which are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.','2013-10-27','NSRP'),(10402,16237,'microautophagy','P','The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.','2013-10-27','NSRP'),(10403,16239,'positive regulation of macroautophagy','P','Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.','2013-10-27','NSRP'),(10404,16240,'autophagic vacuole docking','P','The initial attachment of an autophagic vacuole membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.','2013-10-27','NSRP'),(10405,16241,'regulation of macroautophagy','P','Any process that modulates the frequency, rate or extent of macroautophagy.','2013-10-27','NSRP'),(10406,16242,'negative regulation of macroautophagy','P','Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.','2013-10-27','NSRP'),(10407,16243,'regulation of autophagic vacuole size','P','Any process that modulates the size of the autophagic vacuole.','2013-10-27','NSRP'),(10408,16246,'RNA interference','P','The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation (\'silencing\') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.','2013-10-27','NSRP'),(10409,16247,'channel regulator activity','F','Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.','2013-10-27','NSRP'),(10410,16248,'channel inhibitor activity','F','Stops, prevents, or reduces the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.','2013-10-27','NSRP'),(10411,16250,'N-sulfoglucosamine sulfohydrolase activity','F','Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.','2013-10-27','NSRP'),(10412,16251,'general RNA polymerase II transcription factor activity','F','OBSOLETE. Any function that supports basal (unregulated) transcription of genes by core RNA polymerase II. Five general transcription factors are necessary and sufficient for such basal transcription in yeast: TFIIB, TFIID, TFIIE, TFIIF, TFIIH and TATA-binding protein (TBF).','2013-10-27','NSRP'),(10413,16252,'nonspecific RNA polymerase II transcription factor activity','F','OBSOLETE. Any function that supports transcription of genes by RNA polymerase II, and is not specific to a particular gene or gene set.','2013-10-27','NSRP'),(10414,16254,'preassembly of GPI anchor in ER membrane','P','The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.','2013-10-27','NSRP'),(10415,16255,'attachment of GPI anchor to protein','P','A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.','2013-10-27','NSRP'),(10416,16256,'N-glycan processing to lysosome','P','The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.','2013-10-27','NSRP'),(10417,16257,'N-glycan processing to secreted and cell-surface N-glycans','P','The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.','2013-10-27','NSRP'),(10418,16258,'N-glycan diversification','P','The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.','2013-10-27','NSRP'),(10419,16259,'selenocysteine metabolic process','P','The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.','2013-10-27','NSRP'),(10420,16260,'selenocysteine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.','2013-10-27','NSRP'),(10421,16261,'selenocysteine catabolic process','P','The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.','2013-10-27','NSRP'),(10422,16262,'protein N-acetylglucosaminyltransferase activity','F','Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.','2013-10-27','NSRP'),(10423,16263,'glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity','F','Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.','2013-10-27','NSRP'),(10424,16264,'gap junction assembly','P','Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.','2013-10-27','NSRP'),(10425,16265,'death','P','A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.','2013-10-27','NSRP'),(10426,16266,'O-glycan processing','P','The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.','2013-10-27','NSRP'),(10427,16267,'O-glycan processing, core 1','P','The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.','2013-10-27','NSRP'),(10428,16268,'O-glycan processing, core 2','P','The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.','2013-10-27','NSRP'),(10429,16269,'O-glycan processing, core 3','P','The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.','2013-10-27','NSRP'),(10430,16270,'O-glycan processing, core 4','P','The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.','2013-10-27','NSRP'),(10431,16271,'tissue death','P','A permanent cessation of all vital functions of a tissue.','2013-10-27','NSRP'),(10432,16272,'prefoldin complex','C','A multisubunit chaperone that acts to delivers unfolded proteins to cytosolic chaperonin. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits.','2013-10-27','NSRP'),(10433,16273,'arginine N-methyltransferase activity','F','Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.','2013-10-27','NSRP'),(10434,16274,'protein-arginine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.','2013-10-27','NSRP'),(10435,16275,'[cytochrome c]-arginine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine.','2013-10-27','NSRP'),(10436,16277,'[myelin basic protein]-arginine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.','2013-10-27','NSRP'),(10437,16278,'lysine N-methyltransferase activity','F','Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.','2013-10-27','NSRP'),(10438,16279,'protein-lysine N-methyltransferase activity','F','Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.','2013-10-27','NSRP'),(10439,16281,'eukaryotic translation initiation factor 4F complex','C','The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5\'-terminal secondary structure and recruitment of the mRNA to the ribosome.','2013-10-27','NSRP'),(10440,16282,'eukaryotic 43S preinitiation complex','C','A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.','2013-10-27','NSRP'),(10441,16284,'alanine aminopeptidase activity','F','OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from an oligopeptide or polypeptide.','2013-10-27','NSRP'),(10442,16285,'cytosol alanyl aminopeptidase activity','F','OBSOLETE. Catalysis of the release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.','2013-10-27','NSRP'),(10443,16286,'small conductance calcium-activated potassium channel activity','F','Catalysis of the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.','2013-10-27','NSRP'),(10444,16287,'glycerone-phosphate O-acyltransferase activity','F','Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.','2013-10-27','NSRP'),(10445,16289,'CoA hydrolase activity','F','Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.','2013-10-27','NSRP'),(10446,16290,'palmitoyl-CoA hydrolase activity','F','Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.','2013-10-27','NSRP'),(10447,16291,'acyl-CoA thioesterase activity','F','Catalysis of the reaction: acyl-CoA + H2O = corresponding fatty acid + CoA.','2012-03-14','NSRP'),(10448,16295,'myristoyl-[acyl-carrier-protein] hydrolase activity','F','Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate.','2013-10-27','NSRP'),(10449,16296,'palmitoyl-[acyl-carrier-protein] hydrolase activity','F','Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate.','2013-10-27','NSRP'),(10450,16297,'acyl-[acyl-carrier-protein] hydrolase activity','F','Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid.','2013-10-27','NSRP'),(10451,16298,'lipase activity','F','Catalysis of the hydrolysis of a lipid or phospholipid.','2013-10-27','NSRP'),(10452,16299,'regulator of G-protein signaling activity','F','OBSOLETE. Inhibits signal transduction the GTPase activity of G-protein alpha subunits, thereby driving them into their inactive GDP-bound form.','2013-10-27','NSRP'),(10453,16300,'tRNA (uracil) methyltransferase activity','F','Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.','2013-10-27','NSRP'),(10454,16301,'kinase activity','F','Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.','2013-10-27','NSRP'),(10455,16303,'1-phosphatidylinositol-3-kinase activity','F','Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(10456,16304,'phosphatidylinositol 3-kinase activity, class I','F','OBSOLETE. A heterodimeric phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol, phosphatidylinositol-4-phosphate or phosphatidylinositol-4,5-bisphosphate. Also possesses intrinsic protein kinase activity.','2013-10-27','NSRP'),(10457,16305,'phosphatidylinositol 3-kinase activity, class II','F','OBSOLETE. A phosphoinositide 3-kinase which can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate; the human form can phosphorylate phosphatidylinositol-4,5-bisphosphate in the presence of phosphatidylserine.','2013-10-27','NSRP'),(10458,16306,'phosphatidylinositol 3-kinase activity, class III','F','OBSOLETE. A phosphoinositide 3-kinase which can only phosphorylate phosphatidylinositol.','2013-10-27','NSRP'),(10459,16307,'phosphatidylinositol phosphate kinase activity','F','Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.','2013-10-27','NSRP'),(10460,16308,'1-phosphatidylinositol-4-phosphate 5-kinase activity','F','Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).','2013-10-27','NSRP'),(10461,16309,'1-phosphatidylinositol-5-phosphate 4-kinase activity','F','Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.','2013-10-27','NSRP'),(10462,16310,'phosphorylation','P','The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.','2013-10-27','NSRP'),(10463,16311,'dephosphorylation','P','The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.','2013-10-27','NSRP'),(10464,16312,'inositol bisphosphate phosphatase activity','F','Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.','2013-10-27','NSRP'),(10465,16313,'inositol-1,4,5-trisphosphate phosphatase','F','OBSOLETE. The removal of one of the phosphate groups from an inositol triphosphate to produce an inositol bisphosphate.','2013-10-27','NSRP'),(10466,16314,'phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity','F','Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.','2013-10-27','NSRP'),(10467,16316,'phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity','F','Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.','2013-10-27','NSRP'),(10468,16318,'ommatidial rotation','P','The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.','2013-10-27','NSRP'),(10469,16319,'mushroom body development','P','The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.','2013-10-27','NSRP'),(10470,16320,'endoplasmic reticulum membrane fusion','P','The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.','2013-10-27','NSRP'),(10471,16321,'female meiosis chromosome segregation','P','The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.','2013-10-27','NSRP'),(10472,16322,'neuron remodeling','P','The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.','2013-10-27','NSRP'),(10473,16323,'basolateral plasma membrane','C','The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.','2013-10-27','NSRP'),(10474,16324,'apical plasma membrane','C','The region of the plasma membrane located at the apical end of the cell.','2013-10-27','NSRP'),(10475,16325,'oocyte microtubule cytoskeleton organization','P','Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10476,16326,'kinesin motor activity','F','OBSOLETE. The hydrolysis of ATP (and GTP) that drives the microtubular motor along microtubules.','2013-10-27','NSRP'),(10477,16327,'apicolateral plasma membrane','C','The apical end of the lateral plasma membrane of epithelial cells.','2013-10-27','NSRP'),(10478,16328,'lateral plasma membrane','C','The membranes on the sides of epithelial cells which lie at the interface of adjacent cells.','2013-10-27','NSRP'),(10479,16329,'apoptosis regulator activity','F','OBSOLETE. The function held by products which directly regulate any step in the process of apoptosis.','2013-10-27','NSRP'),(10480,16330,'second mitotic wave involved in compound eye morphogenesis','P','A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.','2013-10-27','NSRP'),(10481,16331,'morphogenesis of embryonic epithelium','P','The process in which the anatomical structures of embryonic epithelia are generated and organized.','2013-10-27','NSRP'),(10482,16332,'establishment or maintenance of polarity of embryonic epithelium','P','Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.','2013-10-27','NSRP'),(10483,16333,'morphogenesis of follicular epithelium','P','The process in which the anatomical structures of a follicular epithelium are generated and organized.','2013-10-27','NSRP'),(10484,16334,'establishment or maintenance of polarity of follicular epithelium','P','Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.','2013-10-27','NSRP'),(10485,16335,'morphogenesis of larval imaginal disc epithelium','P','The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.','2013-10-27','NSRP'),(10486,16336,'establishment or maintenance of polarity of larval imaginal disc epithelium','P','Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.','2013-10-27','NSRP'),(10487,16337,'cell-cell adhesion','P','The attachment of one cell to another cell via adhesion molecules.','2013-10-27','NSRP'),(10488,16338,'calcium-independent cell-cell adhesion','P','The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.','2013-10-27','NSRP'),(10489,16339,'calcium-dependent cell-cell adhesion','P','The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.','2013-10-27','NSRP'),(10490,16340,'calcium-dependent cell-matrix adhesion','P','The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.','2013-10-27','NSRP'),(10491,16341,'other collagen','C','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10492,16342,'catenin complex','C','Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.','2013-10-27','NSRP'),(10493,16343,'cytoskeletal anchoring activity','F','OBSOLETE. The direct or indirect linkage of cytoskeletal filaments to the plasma membrane.','2013-10-27','NSRP'),(10494,16344,'meiotic chromosome movement towards spindle pole','P','The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.','2013-10-27','NSRP'),(10495,16345,'female meiotic chromosome movement towards spindle pole','P','The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.','2013-10-27','NSRP'),(10496,16346,'male meiotic chromosome movement towards spindle pole','P','The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.','2013-10-27','NSRP'),(10497,16347,'calcium-independent cell adhesion molecule activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10498,16348,'imaginal disc-derived leg joint morphogenesis','P','The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10499,16351,'drug susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10500,16352,'insecticide susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10501,16353,'carbamate susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10502,16354,'cyclodiene susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10503,16355,'DDT susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10504,16356,'organophosphorus susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10505,16357,'pyrethroid susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10506,16358,'dendrite development','P','The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell.','2013-10-27','NSRP'),(10507,16360,'sensory organ precursor cell fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.','2013-10-27','NSRP'),(10508,16361,'activin receptor activity, type I','F','Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.','2013-10-27','NSRP'),(10509,16362,'activin receptor activity, type II','F','Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.','2013-10-27','NSRP'),(10510,16363,'nuclear matrix','C','The dense fibrillar network lying on the inner side of the nuclear membrane.','2013-10-27','NSRP'),(10511,16401,'palmitoyl-CoA oxidase activity','F','Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.','2013-10-27','NSRP'),(10512,16402,'pristanoyl-CoA oxidase activity','F','Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.','2013-10-27','NSRP'),(10513,16403,'dimethylargininase activity','F','Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.','2013-10-27','NSRP'),(10514,16404,'15-hydroxyprostaglandin dehydrogenase (NAD+) activity','F','Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.','2013-10-27','NSRP'),(10515,16405,'CoA-ligase activity','F','Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.','2013-10-27','NSRP'),(10516,16406,'carnitine O-acyltransferase activity','F','Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.','2013-10-27','NSRP'),(10517,16407,'acetyltransferase activity','F','Catalysis of the transfer of an acetyl group to an acceptor molecule.','2013-10-27','NSRP'),(10518,16408,'C-acyltransferase activity','F','Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.','2013-10-27','NSRP'),(10519,16409,'palmitoyltransferase activity','F','Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.','2013-10-27','NSRP'),(10520,16410,'N-acyltransferase activity','F','Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.','2013-10-27','NSRP'),(10521,16411,'acylglycerol O-acyltransferase activity','F','Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.','2013-10-27','NSRP'),(10522,16412,'serine O-acyltransferase activity','F','Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule.','2013-10-27','NSRP'),(10523,16413,'O-acetyltransferase activity','F','Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(10524,16414,'O-octanoyltransferase activity','F','Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(10525,16415,'octanoyltransferase activity','F','Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.','2013-10-27','NSRP'),(10526,16416,'O-palmitoyltransferase activity','F','Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(10527,16417,'S-acyltransferase activity','F','Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.','2013-10-27','NSRP'),(10528,16418,'S-acetyltransferase activity','F','Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.','2013-10-27','NSRP'),(10529,16419,'S-malonyltransferase activity','F','Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.','2013-10-27','NSRP'),(10530,16420,'malonyltransferase activity','F','Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.','2013-10-27','NSRP'),(10531,16421,'CoA carboxylase activity','F','Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10532,16422,'mRNA (2\'-O-methyladenosine-N6-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5\')pppAm = S-adenosyl-L-homocysteine + m(7)G(5\')pppm(6)Am.','2013-10-27','NSRP'),(10533,16423,'tRNA (guanine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.','2013-10-27','NSRP'),(10534,16426,'tRNA (adenine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.','2013-10-27','NSRP'),(10535,16427,'tRNA (cytosine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.','2013-10-27','NSRP'),(10536,16428,'tRNA (cytosine-5-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.','2013-10-27','NSRP'),(10537,16429,'tRNA (adenine-N1-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine.','2013-10-27','NSRP'),(10538,16430,'tRNA (adenine-N6-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.','2013-10-27','NSRP'),(10539,16432,'tRNA-uridine aminocarboxypropyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5\'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.','2013-10-27','NSRP'),(10540,16433,'rRNA (adenine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.','2013-10-27','NSRP'),(10541,16434,'rRNA (cytosine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.','2013-10-27','NSRP'),(10542,16435,'rRNA (guanine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.','2013-10-27','NSRP'),(10543,16436,'rRNA (uridine) methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.','2013-10-27','NSRP'),(10544,16437,'tRNA cytidylyltransferase activity','F','Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1).','2013-10-27','NSRP'),(10545,16438,'tRNA-queuosine beta-mannosyltransferase activity','F','Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5\'\'-beta-D-mannosylqueuosine.','2013-10-27','NSRP'),(10546,16441,'posttranscriptional gene silencing','P','The inactivation of gene expression by a posttranscriptional mechanism.','2013-10-27','NSRP'),(10547,16442,'RISC complex','C','A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.','2013-10-27','NSRP'),(10548,16443,'bidentate ribonuclease III activity','F','Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.','2013-10-27','NSRP'),(10549,16444,'somatic cell DNA recombination','P','Recombination occurring within or between DNA molecules in somatic cells.','2013-10-27','NSRP'),(10550,16445,'somatic diversification of immunoglobulins','P','The somatic process that results in the generation of sequence diversity of immunoglobulins.','2013-10-27','NSRP'),(10551,16446,'somatic hypermutation of immunoglobulin genes','P','Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.','2013-10-27','NSRP'),(10552,16447,'somatic recombination of immunoglobulin gene segments','P','The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.','2013-10-27','NSRP'),(10553,16453,'C-acetyltransferase activity','F','Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.','2013-10-27','NSRP'),(10554,16454,'C-palmitoyltransferase activity','F','Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.','2013-10-27','NSRP'),(10555,16456,'X chromosome located dosage compensation complex, transcription activating','C','An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10556,16457,'dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome','P','The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10557,16458,'gene silencing','P','Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.','2013-10-27','NSRP'),(10558,16459,'myosin complex','C','A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.','2013-10-27','NSRP'),(10559,16460,'myosin II complex','C','A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.','2013-10-27','NSRP'),(10560,16461,'unconventional myosin complex','C','A portmanteau term for myosins other than myosin II.','2013-10-27','NSRP'),(10561,16462,'pyrophosphatase activity','F','Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.','2013-10-27','NSRP'),(10562,16463,'zinc-exporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).','2013-10-27','NSRP'),(10563,16464,'chloroplast protein-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.','2013-10-27','NSRP'),(10564,16465,'chaperonin ATPase complex','C','Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.','2013-10-27','NSRP'),(10565,16466,'hydrogen-translocating A-type ATPase activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in archae.','2013-10-27','NSRP'),(10566,16467,'hydrogen-translocating F-type ATPase activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.','2013-10-27','NSRP'),(10567,16468,'sodium-translocating F-type ATPase activity','F','OBSOLETE. Catalysis of the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out). Found in eukaryotic mitochondria and chloroplasts and in bacteria.','2013-10-27','NSRP'),(10568,16469,'proton-transporting two-sector ATPase complex','C','A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.','2013-10-27','NSRP'),(10569,16471,'vacuolar proton-transporting V-type ATPase complex','C','A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.','2013-10-27','NSRP'),(10570,16472,'sodium ion-transporting two-sector ATPase complex','C','A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.','2013-10-27','NSRP'),(10571,16473,'sodium ion-transporting F-type ATPase complex','C','A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.','2013-10-27','NSRP'),(10572,16474,'sodium ion-transporting V-type ATPase complex','C','A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.','2013-10-27','NSRP'),(10573,16475,'detection of nuclear:cytoplasmic ratio','P','The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.','2013-10-27','NSRP'),(10574,16476,'regulation of embryonic cell shape','P','Any process that modulates the surface configuration of an embryonic cell.','2013-10-27','NSRP'),(10575,16477,'cell migration','P','The orderly movement of a cell from one site to another, often during the development of a multicellular organism or multicellular structure.','2013-10-27','NSRP'),(10576,16479,'negative regulation of transcription from RNA polymerase I promoter','P','Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter.','2013-10-27','NSRP'),(10577,16480,'negative regulation of transcription from RNA polymerase III promoter','P','Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter.','2013-10-27','NSRP'),(10578,16482,'cytoplasmic transport','P','The directed movement of substances (such as macromolecules, small molecules, ions) into, out of, or within the cytoplasm of a cell.','2013-10-27','NSRP'),(10579,16483,'tryptophan hydroxylase activator activity','F','Increases the activity of the enzyme tryptophase hydroxylase.','2013-10-27','NSRP'),(10580,16484,'proprotein convertase 2 activator activity','F','OBSOLETE. Required for the maturation and activation of proprotein convertase 2.','2013-10-27','NSRP'),(10581,16485,'protein processing','P','Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.','2013-10-27','NSRP'),(10582,16486,'peptide hormone processing','P','The generation of a mature peptide hormone by posttranslational processing of a prohormone.','2013-10-27','NSRP'),(10583,16487,'farnesol metabolic process','P','The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.','2013-10-27','NSRP'),(10584,16488,'farnesol catabolic process','P','The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.','2013-10-27','NSRP'),(10585,16490,'structural constituent of peritrophic membrane','F','The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10586,16491,'oxidoreductase activity','F','Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.','2013-10-27','NSRP'),(10587,16492,'G-protein coupled neurotensin receptor activity','F','Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.','2013-10-27','NSRP'),(10588,16493,'C-C chemokine receptor activity','F','Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.','2013-10-27','NSRP'),(10589,16494,'C-X-C chemokine receptor activity','F','Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.','2013-10-27','NSRP'),(10590,16495,'C-X3-C chemokine receptor activity','F','Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.','2013-10-27','NSRP'),(10591,16496,'substance P receptor activity','F','Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.','2013-10-27','NSRP'),(10592,16497,'substance K receptor activity','F','Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.','2013-10-27','NSRP'),(10593,16498,'neuromedin K receptor activity','F','Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.','2013-10-27','NSRP'),(10594,16499,'orexin receptor activity','F','Combining with orexin to initiate a change in cell activity.','2013-10-27','NSRP'),(10595,16500,'protein-hormone receptor activity','F','Combining with a protein hormone to initiate a change in cell activity.','2013-10-27','NSRP'),(10596,16501,'prostacyclin receptor activity','F','Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.','2013-10-27','NSRP'),(10597,16502,'nucleotide receptor activity','F','Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.','2013-10-27','NSRP'),(10598,16503,'pheromone receptor activity','F','Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.','2013-10-27','NSRP'),(10599,16504,'peptidase activator activity','F','Increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.','2013-10-27','NSRP'),(10600,16505,'peptidase activator activity involved in apoptotic process','F','Increases the activity of a peptidase that is involved in the apoptotic process.','2013-10-27','NSRP'),(10601,16506,'apoptosis activator activity','F','OBSOLETE. The function held by products which directly activate any step in the process of apoptosis.','2013-10-27','NSRP'),(10602,16507,'mitochondrial fatty acid beta-oxidation multienzyme complex','C','A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix.','2013-10-27','NSRP'),(10603,16508,'long-chain-enoyl-CoA hydratase activity','F','Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms.','2013-10-27','NSRP'),(10604,16509,'long-chain-3-hydroxyacyl-CoA dehydrogenase activity','F','Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.','2013-10-27','NSRP'),(10605,16511,'endothelin-converting enzyme activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10606,16512,'endothelin-converting enzyme 1 activity','F','OBSOLETE. Catalysis of the formation of endothelin 1 by cleavage of the Trp21-Val22 bond in the precursor.','2013-10-27','NSRP'),(10607,16513,'core-binding factor complex','C','A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5\'-YGYGGTY-3\' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.','2013-10-27','NSRP'),(10608,16514,'SWI/SNF complex','C','A SWI/SNF-type complex that contains nine or more proteins, including both conserved (core) and nonconserved components; the Swi2/Snf2 ATPase is one of the core components.','2013-10-27','NSRP'),(10609,16515,'interleukin-13 receptor activity','F','Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(10610,16516,'interleukin-4 receptor complex','C','A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.','2013-10-27','NSRP'),(10611,16517,'interleukin-12 receptor activity','F','Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(10612,16518,'interleukin-14 receptor activity','F','Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(10613,16519,'gastric inhibitory peptide receptor activity','F','Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.','2013-10-27','NSRP'),(10614,16520,'growth hormone-releasing hormone receptor activity','F','Combining with growth hormone-releasing hormone to initiate a change in cell activity.','2013-10-27','NSRP'),(10615,16521,'pituitary adenylate cyclase activating polypeptide activity','F','The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.','2013-10-27','NSRP'),(10616,16524,'latrotoxin receptor activity','F','Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(10617,16525,'negative regulation of angiogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.','2013-10-27','NSRP'),(10618,16527,'brain-specific angiogenesis inhibitor activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10619,16528,'sarcoplasm','C','The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.','2013-10-27','NSRP'),(10620,16529,'sarcoplasmic reticulum','C','A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.','2013-10-27','NSRP'),(10621,16530,'metallochaperone activity','F','Assists in the delivery of metal ions to target proteins or compartments.','2013-10-27','NSRP'),(10622,16531,'copper chaperone activity','F','Assists in the delivery of copper ions to target proteins or compartments.','2013-10-27','NSRP'),(10623,16532,'superoxide dismutase copper chaperone activity','F','A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase.','2013-10-27','NSRP'),(10624,16533,'cyclin-dependent protein kinase 5 holoenzyme complex','C','A protein complex that activates cyclin-dependent kinase 5; composed of regulatory and catalytic subunits.','2013-10-27','NSRP'),(10625,16534,'cyclin-dependent protein kinase 5 activator activity','F','Increases the activity of cyclin-dependent protein kinase 5.','2013-10-27','NSRP'),(10626,16536,'cyclin-dependent protein kinase 5 activator regulator activity','F','Modulation of the activity of cyclin-dependent protein kinase 5 activator.','2013-10-27','NSRP'),(10627,16538,'cyclin-dependent protein serine/threonine kinase regulator activity','F','Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.','2013-10-27','NSRP'),(10628,16539,'intein-mediated protein splicing','P','The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.','2013-10-27','NSRP'),(10629,16540,'protein autoprocessing','P','Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.','2013-10-27','NSRP'),(10630,16541,'intein','F','OBSOLETE. Intervening protein sequence excised from a protein precursor in protein splicing; inteins catalyze their own excision and many also possess endonuclease activity.','2013-10-27','NSRP'),(10631,16543,'male courtship behavior, orientation prior to leg tapping and wing vibration','P','The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10632,16544,'male courtship behavior, tapping to detect pheromone','P','The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10633,16545,'male courtship behavior, veined wing vibration','P','The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10634,16546,'male courtship behavior, proboscis-mediated licking','P','The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.','2013-10-27','NSRP'),(10635,16550,'insertion or deletion editing','P','OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during or after transcription.','2013-10-27','NSRP'),(10636,16551,'posttranscriptional insertion or deletion editing','P','OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place after transcription.','2013-10-27','NSRP'),(10637,16552,'cotranscriptional insertion or deletion editing','P','OBSOLETE. The insertion into or deletion from an RNA molecule of nucleotide residues not encoded in DNA; takes place during transcription.','2013-10-27','NSRP'),(10638,16553,'base conversion or substitution editing','P','Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).','2013-10-27','NSRP'),(10639,16554,'cytidine to uridine editing','P','The conversion of a cytosine residue to uridine in an RNA molecule by deamination.','2013-10-27','NSRP'),(10640,16555,'uridine to cytidine editing','P','The conversion of a uridine residue to cytosine in an RNA molecule by amination.','2013-10-27','NSRP'),(10641,16556,'mRNA modification','P','The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.','2013-10-27','NSRP'),(10642,16557,'peroxisome membrane biogenesis','P','The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.','2013-10-27','NSRP'),(10643,16558,'protein import into peroxisome matrix','P','The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.','2013-10-27','NSRP'),(10644,16559,'peroxisome fission','P','The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.','2013-10-27','NSRP'),(10645,16560,'protein import into peroxisome matrix, docking','P','The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the preoxisomal membrane.','2013-10-27','NSRP'),(10646,16561,'protein import into peroxisome matrix, translocation','P','The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.','2013-10-27','NSRP'),(10647,16562,'protein import into peroxisome matrix, receptor recycling','P','The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.','2013-10-27','NSRP'),(10648,16563,'transcription activator activity','F','OBSOLETE. Any transcription regulator activity required for initiation or upregulation of transcription.','2013-10-27','NSRP'),(10649,16564,'transcription repressor activity','F','OBSOLETE. Any transcription regulator activity that prevents or downregulates transcription.','2013-10-27','NSRP'),(10650,16565,'general transcriptional repressor activity','F','OBSOLETE. Any activity that stops or downregulates transcription of genes globally, and is not specific to a particular gene or gene set.','2013-10-27','NSRP'),(10651,16566,'specific transcriptional repressor activity','F','OBSOLETE. Any activity that stops or downregulates transcription of specific genes or sets of genes.','2013-10-27','NSRP'),(10652,16567,'protein ubiquitination','P','The process in which one or more ubiquitin groups are added to a protein.','2013-10-27','NSRP'),(10653,16568,'chromatin modification','P','The alteration of DNA, protein, or sometimes RNA, in chromatin, which may result in changing the chromatin structure.','2013-10-27','NSRP'),(10654,16569,'covalent chromatin modification','P','The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.','2013-10-27','NSRP'),(10655,16570,'histone modification','P','The covalent alteration of one or more amino acid residues within a histone protein.','2013-10-27','NSRP'),(10656,16571,'histone methylation','P','The modification of histones by addition of methyl groups.','2013-10-27','NSRP'),(10657,16572,'histone phosphorylation','P','The modification of histones by addition of phosphate groups.','2013-10-27','NSRP'),(10658,16573,'histone acetylation','P','The modification of a histone by the addition of an acetyl group.','2013-10-27','NSRP'),(10659,16574,'histone ubiquitination','P','The modification of histones by addition of ubiquitin groups.','2013-10-27','NSRP'),(10660,16575,'histone deacetylation','P','The modification of histones by removal of acetyl groups.','2013-10-27','NSRP'),(10661,16576,'histone dephosphorylation','P','The modification of histones by removal of phosphate groups.','2013-10-27','NSRP'),(10662,16577,'histone demethylation','P','The modification of histones by removal of methyl groups.','2013-10-27','NSRP'),(10663,16578,'histone deubiquitination','P','The modification of histones by removal of ubiquitin groups.','2013-10-27','NSRP'),(10664,16579,'protein deubiquitination','P','The removal of one or more ubiquitin groups from a protein.','2013-10-27','NSRP'),(10665,16580,'Sin3 complex','C','A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.','2013-10-27','NSRP'),(10666,16581,'NuRD complex','C','An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.','2013-10-27','NSRP'),(10667,16582,'non-covalent chromatin modification','P','The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups.','2013-10-27','NSRP'),(10668,16583,'nucleosome modeling','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10669,16584,'nucleosome positioning','P','Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.','2013-10-27','NSRP'),(10670,16585,'chromatin remodeling complex','C','OBSOLETE: Any complex that mediates dynamic changes in eukaryotic chromatin.','2013-10-27','NSRP'),(10671,16586,'RSC complex','C','A protein complex similar to, but more abundant than, the Swi/Snf complex. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.','2013-10-27','NSRP'),(10672,16587,'Isw1 complex','C','A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.','2013-10-27','NSRP'),(10673,16589,'NURF complex','C','An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.','2013-10-27','NSRP'),(10674,16590,'ACF complex','C','An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.','2013-10-27','NSRP'),(10675,16591,'DNA-directed RNA polymerase II, holoenzyme','C','Large protein complex composed of the RNA polymerase core complex and a variety of other proteins including transcription factor complexes TFIIA, D, E, F, and H which are required for promoter recognition, and the Mediator subcomplex. Catalyzes the synthesis of eukaryotic pre-mRNA.','2013-10-27','NSRP'),(10676,16592,'mediator complex','C','A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.','2013-10-27','NSRP'),(10677,16593,'Cdc73/Paf1 complex','C','A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.','2013-10-27','NSRP'),(10678,16594,'glycine binding','F','Interacting selectively and non-covalently with glycine, aminoethanoic acid.','2013-10-27','NSRP'),(10679,16595,'glutamate binding','F','Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.','2013-10-27','NSRP'),(10680,16596,'thienylcyclohexylpiperidine binding','F','Interacting selectively and non-covalently with thienylcyclohexylpiperidine.','2013-10-27','NSRP'),(10681,16597,'amino acid binding','F','Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.','2013-10-27','NSRP'),(10682,16598,'protein arginylation','P','The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.','2013-10-27','NSRP'),(10683,16600,'flotillin complex','C','A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.','2013-10-27','NSRP'),(10684,16601,'Rac protein signal transduction','P','A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.','2013-10-27','NSRP'),(10685,16602,'CCAAT-binding factor complex','C','A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; in Saccharomyces it activates the transcription of genes in response to growth in a nonfermentable carbon source; consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.','2013-10-27','NSRP'),(10686,16603,'glutaminyl-peptide cyclotransferase activity','F','Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.','2013-10-27','NSRP'),(10687,16604,'nuclear body','C','Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.','2013-10-27','NSRP'),(10688,16605,'PML body','C','A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.','2013-10-27','NSRP'),(10689,16606,'LYSP100-associated nuclear domain','C','A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.','2013-10-27','NSRP'),(10690,16607,'nuclear speck','C','A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.','2013-10-27','NSRP'),(10691,16608,'growth hormone-releasing hormone activity','F','The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.','2013-10-27','NSRP'),(10692,16610,'nitrogenase complex','C','An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.','2013-10-27','NSRP'),(10693,16611,'iron-iron nitrogenase complex','C','An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.','2013-10-27','NSRP'),(10694,16612,'molybdenum-iron nitrogenase complex','C','An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.','2013-10-27','NSRP'),(10695,16613,'vanadium-iron nitrogenase complex','C','An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.','2013-10-27','NSRP'),(10696,16614,'oxidoreductase activity, acting on CH-OH group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10697,16615,'malate dehydrogenase activity','F','Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.','2013-10-27','NSRP'),(10698,16616,'oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.','2013-10-27','NSRP'),(10699,16617,'4-oxoproline reductase activity','F','Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.','2013-10-27','NSRP'),(10700,16618,'hydroxypyruvate reductase activity','F','Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.','2013-10-27','NSRP'),(10701,16619,'malate dehydrogenase (oxaloacetate-decarboxylating) activity','F','Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. Also decarboxylates oxaloacetate.','2013-10-27','NSRP'),(10702,16620,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10703,16621,'cinnamoyl-CoA reductase activity','F','Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+.','2013-10-27','NSRP'),(10704,16622,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10705,16623,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10706,16624,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.','2013-10-27','NSRP'),(10707,16625,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10708,16626,'oxidoreductase activity, acting on the aldehyde or oxo group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an acceptor other than NAD, NADP, oxygen, an iron-sulfur protein, disulphide or a cytochrome.','2013-10-27','NSRP'),(10709,16627,'oxidoreductase activity, acting on the CH-CH group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10710,16628,'oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10711,16629,'12-oxophytodienoate reductase activity','F','Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH.','2013-10-27','NSRP'),(10712,16630,'protochlorophyllide reductase activity','F','Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.','2013-10-27','NSRP'),(10713,16631,'enoyl-[acyl-carrier-protein] reductase activity','F','Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.','2013-10-27','NSRP'),(10714,16632,'oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10715,16633,'galactonolactone dehydrogenase activity','F','Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.','2013-10-27','NSRP'),(10716,16634,'oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10717,16635,'oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.','2013-10-27','NSRP'),(10718,16636,'oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10719,16637,'oxidoreductase activity, acting on the CH-CH group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or related compound, a cytochrome, an iron-sulfur protein, NAD, NADP or oxygen.','2013-10-27','NSRP'),(10720,16638,'oxidoreductase activity, acting on the CH-NH2 group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10721,16639,'oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.','2013-10-27','NSRP'),(10722,16640,'oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.','2013-10-27','NSRP'),(10723,16641,'oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.','2013-10-27','NSRP'),(10724,16642,'oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.','2013-10-27','NSRP'),(10725,16643,'oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10726,16644,'oxidoreductase activity, acting on the CH-NH2 group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, an iron-sulfur protein, NAD, NADP or oxygen.','2013-10-27','NSRP'),(10727,16645,'oxidoreductase activity, acting on the CH-NH group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10728,16646,'oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10729,16647,'oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10730,16648,'oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.','2013-10-27','NSRP'),(10731,16649,'oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.','2013-10-27','NSRP'),(10732,16650,'oxidoreductase activity, acting on the CH-NH group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or similar compound, disulfide, NAD, NADP, oxygen or a flavin.','2013-10-27','NSRP'),(10733,16651,'oxidoreductase activity, acting on NAD(P)H','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10734,16652,'oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.','2013-10-27','NSRP'),(10735,16653,'oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.','2013-10-27','NSRP'),(10736,16655,'oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.','2013-10-27','NSRP'),(10737,16656,'monodehydroascorbate reductase (NADH) activity','F','Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.','2013-10-27','NSRP'),(10738,16657,'oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.','2013-10-27','NSRP'),(10739,16658,'oxidoreductase activity, acting on NADH or NADPH, flavin as acceptor','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10740,16659,'oxidoreductase activity, acting on NADH or NADPH, other acceptor','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, a heme protein, NAD, NADP, a nitrogenous group, a quinone or similar compound or oxygen.','2013-10-27','NSRP'),(10741,16661,'oxidoreductase activity, acting on other nitrogenous compounds as donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10742,16662,'oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10743,16663,'oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10744,16664,'oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10745,16665,'oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, oxygen, NAD or NADP.','2013-10-27','NSRP'),(10746,16667,'oxidoreductase activity, acting on a sulfur group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10747,16668,'oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10748,16669,'oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10749,16670,'oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10750,16671,'oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.','2013-10-27','NSRP'),(10751,16672,'oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.','2013-10-27','NSRP'),(10752,16673,'oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10753,16674,'oxidoreductase activity, acting on sulfur group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an acceptor other than quinone or a related compound, oxygen, NAD, NADP, an iron-sulfur protein, disulfide or a cytochrome.','2013-10-27','NSRP'),(10754,16675,'oxidoreductase activity, acting on a heme group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10755,16676,'oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10756,16677,'oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.','2013-10-27','NSRP'),(10757,16678,'oxidoreductase activity, acting on heme group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces an acceptor other than a nitrogenous group or oxygen.','2013-10-27','NSRP'),(10758,16679,'oxidoreductase activity, acting on diphenols and related substances as donors','F','Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10759,16680,'oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10760,16681,'oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10761,16682,'oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.','2013-10-27','NSRP'),(10762,16683,'oxidoreductase activity, acting on diphenols and related substances as donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, NAD, NADP or oxygen.','2013-10-27','NSRP'),(10763,16684,'oxidoreductase activity, acting on peroxide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10764,16688,'L-ascorbate peroxidase activity','F','Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.','2013-10-27','NSRP'),(10765,16689,'manganese peroxidase activity','F','Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.','2013-10-27','NSRP'),(10766,16690,'diarylpropane peroxidase activity','F','Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.','2013-10-27','NSRP'),(10767,16691,'chloride peroxidase activity','F','Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O.','2013-10-27','NSRP'),(10768,16692,'NADH peroxidase activity','F','Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+).','2013-10-27','NSRP'),(10769,16694,'bacterial catalase-peroxidase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10770,16695,'oxidoreductase activity, acting on hydrogen as donor','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.','2013-10-27','NSRP'),(10771,16696,'oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10772,16697,'oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.','2013-10-27','NSRP'),(10773,16699,'oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.','2013-10-27','NSRP'),(10774,16700,'oxidoreductase activity, acting on hydrogen as donor, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which hydrogen is the electron donor and reduces an acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP or a quinone or similar compound.','2013-10-27','NSRP'),(10775,16701,'oxidoreductase activity, acting on single donors with incorporation of molecular oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.','2013-10-27','NSRP'),(10776,16702,'oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.','2013-10-27','NSRP'),(10777,16703,'oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.','2013-10-27','NSRP'),(10778,16704,'oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, miscellaneous','F','OBSOLETE. A grouping term for oxidoreductases acting on single donors with incorporation of molecular oxygen that cannot be more accurated categorized.','2013-10-27','NSRP'),(10779,16705,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.','2013-10-27','NSRP'),(10780,16706,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors','F','Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.','2013-10-27','NSRP'),(10781,16707,'gibberellin 3-beta-dioxygenase activity','F','Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.','2013-10-27','NSRP'),(10782,16708,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.','2013-10-27','NSRP'),(10783,16709,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10784,16710,'trans-cinnamate 4-monooxygenase activity','F','Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.','2013-10-27','NSRP'),(10785,16711,'flavonoid 3\'-monooxygenase activity','F','Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3\'-hydroxyflavonoid + NADP+ + H2O.','2013-10-27','NSRP'),(10786,16712,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10787,16713,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10788,16714,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10789,16715,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10790,16716,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.','2013-10-27','NSRP'),(10791,16717,'oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water','F','Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.','2013-10-27','NSRP'),(10792,16718,'oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, miscellaneous','F','OBSOLETE. A grouping term for oxidoreductases, acting on paired donors with incorporation or reduction of molecular oxygen, that cannot be more accurately categorized.','2013-10-27','NSRP'),(10793,16719,'carotene 7,8-desaturase activity','F','Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.','2013-10-27','NSRP'),(10794,16720,'delta12-fatty acid dehydrogenase activity','F','Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O.','2013-10-27','NSRP'),(10795,16721,'oxidoreductase activity, acting on superoxide radicals as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10796,16722,'oxidoreductase activity, oxidizing metal ions','F','Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.','2013-10-27','NSRP'),(10797,16723,'oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor.','2013-10-27','NSRP'),(10798,16724,'oxidoreductase activity, oxidizing metal ions, oxygen as acceptor','F','Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.','2013-10-27','NSRP'),(10799,16725,'oxidoreductase activity, acting on CH or CH2 groups','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10800,16726,'oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.','2013-10-27','NSRP'),(10801,16727,'oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.','2013-10-27','NSRP'),(10802,16728,'oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.','2013-10-27','NSRP'),(10803,16729,'oxidoreductase activity, acting on CH2 groups, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an acceptor other than disulfide, NAD, NADP or oxygen.','2013-10-27','NSRP'),(10804,16730,'oxidoreductase activity, acting on iron-sulfur proteins as donors','F','Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10805,16731,'oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.','2013-10-27','NSRP'),(10806,16732,'oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.','2013-10-27','NSRP'),(10807,16733,'iron-iron nitrogenase activity','F','OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.','2013-10-27','NSRP'),(10808,16734,'molybdenum-iron nitrogenase activity','F','OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + N2 + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.','2013-10-27','NSRP'),(10809,16735,'vanadium-iron nitrogenase activity','F','OBSOLETE. Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.','2013-10-27','NSRP'),(10810,16737,'oxidoreductase activity, acting on reduced flavodoxin as donor','F','Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10811,16738,'oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.','2013-10-27','NSRP'),(10812,16739,'oxidoreductase activity, acting on other substrates','F','OBSOLETE. A grouping term for oxidoreductase that cannot be more accurately categorized.','2013-10-27','NSRP'),(10813,16740,'transferase activity','F','Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.','2013-10-27','NSRP'),(10814,16741,'transferase activity, transferring one-carbon groups','F','Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10815,16742,'hydroxymethyl-, formyl- and related transferase activity','F','Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10816,16743,'carboxyl- or carbamoyltransferase activity','F','Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10817,16744,'transferase activity, transferring aldehyde or ketonic groups','F','Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10818,16746,'transferase activity, transferring acyl groups','F','Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10819,16747,'transferase activity, transferring acyl groups other than amino-acyl groups','F','Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10820,16748,'succinyltransferase activity','F','Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.','2013-10-27','NSRP'),(10821,16749,'N-succinyltransferase activity','F','Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.','2013-10-27','NSRP'),(10822,16750,'O-succinyltransferase activity','F','Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(10823,16751,'S-succinyltransferase activity','F','Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.','2013-10-27','NSRP'),(10824,16752,'sinapoyltransferase activity','F','Catalysis of the transfer of a sinapoyl group to an acceptor molecule.','2013-10-27','NSRP'),(10825,16753,'O-sinapoyltransferase activity','F','Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.','2013-10-27','NSRP'),(10826,16754,'sinapoylglucose-malate O-sinapoyltransferase activity','F','Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.','2013-10-27','NSRP'),(10827,16755,'transferase activity, transferring amino-acyl groups','F','Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10828,16756,'glutathione gamma-glutamylcysteinyltransferase activity','F','Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.','2013-10-27','NSRP'),(10829,16757,'transferase activity, transferring glycosyl groups','F','Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10830,16758,'transferase activity, transferring hexosyl groups','F','Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10831,16759,'cellulose synthase activity','F','Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).','2013-10-27','NSRP'),(10832,16760,'cellulose synthase (UDP-forming) activity','F','Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).','2013-10-27','NSRP'),(10833,16761,'cellulose synthase (GDP-forming) activity','F','Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).','2013-10-27','NSRP'),(10834,16762,'xyloglucan:xyloglucosyl transferase activity','F','Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.','2013-10-27','NSRP'),(10835,16763,'transferase activity, transferring pentosyl groups','F','Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10836,16764,'transferase activity, transferring other glycosyl groups','F','OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10837,16765,'transferase activity, transferring alkyl or aryl (other than methyl) groups','F','Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10838,16767,'geranylgeranyl-diphosphate geranylgeranyltransferase activity','F','Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.','2013-10-27','NSRP'),(10839,16768,'spermine synthase activity','F','Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5\'-methylthioadenosine + spermine.','2013-10-27','NSRP'),(10840,16769,'transferase activity, transferring nitrogenous groups','F','Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10841,16770,'oximinotransaminase activity','F','Catalysis of the reversible transfer of an oxime group to an acceptor.','2013-10-27','NSRP'),(10842,16771,'transferase activity, transferring other nitrogenous groups','F','OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10843,16772,'transferase activity, transferring phosphorus-containing groups','F','Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10844,16773,'phosphotransferase activity, alcohol group as acceptor','F','Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).','2013-10-27','NSRP'),(10845,16774,'phosphotransferase activity, carboxyl group as acceptor','F','Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).','2013-10-27','NSRP'),(10846,16775,'phosphotransferase activity, nitrogenous group as acceptor','F','Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).','2013-10-27','NSRP'),(10847,16776,'phosphotransferase activity, phosphate group as acceptor','F','Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).','2013-10-27','NSRP'),(10848,16778,'diphosphotransferase activity','F','Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).','2013-10-27','NSRP'),(10849,16779,'nucleotidyltransferase activity','F','Catalysis of the transfer of a nucleotidyl group to a reactant.','2013-10-27','NSRP'),(10850,16780,'phosphotransferase activity, for other substituted phosphate groups','F','Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).','2013-10-27','NSRP'),(10851,16781,'phosphotransferase activity, paired acceptors','F','Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.','2013-10-27','NSRP'),(10852,16782,'transferase activity, transferring sulfur-containing groups','F','Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10853,16783,'sulfurtransferase activity','F','Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10854,16784,'3-mercaptopyruvate sulfurtransferase activity','F','Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.','2013-10-27','NSRP'),(10855,16785,'transferase activity, transferring selenium-containing groups','F','Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).','2013-10-27','NSRP'),(10856,16787,'hydrolase activity','F','Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.','2013-10-27','NSRP'),(10857,16788,'hydrolase activity, acting on ester bonds','F','Catalysis of the hydrolysis of any ester bond.','2013-10-27','NSRP'),(10858,16790,'thiolester hydrolase activity','F','Catalysis of the reaction: RCO-SR\' + H2O = RCOOH + HSR\'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR\'), such as that found in acetyl-coenzyme A.','2013-10-27','NSRP'),(10859,16791,'phosphatase activity','F','Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.','2013-10-27','NSRP'),(10860,16793,'triphosphoric monoester hydrolase activity','F','Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.','2013-10-27','NSRP'),(10861,16794,'diphosphoric monoester hydrolase activity','F','Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.','2013-10-27','NSRP'),(10862,16795,'phosphoric triester hydrolase activity','F','Catalysis of the hydrolysis of a phosphoric triester.','2013-10-27','NSRP'),(10863,16796,'exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3\' or 5\' end to yield 5\' phosphomonoesters.','2013-10-27','NSRP'),(10864,16797,'exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3\' or 5\' end to yield 3\' phosphomonoesters.','2013-10-27','NSRP'),(10865,16798,'hydrolase activity, acting on glycosyl bonds','F','Catalysis of the hydrolysis of any glycosyl bond.','2013-10-27','NSRP'),(10866,16799,'hydrolase activity, hydrolyzing N-glycosyl compounds','F','Catalysis of the hydrolysis of any N-glycosyl bond.','2013-10-27','NSRP'),(10867,16801,'hydrolase activity, acting on ether bonds','F','Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.','2013-10-27','NSRP'),(10868,16802,'trialkylsulfonium hydrolase activity','F','Catalysis of the hydrolysis of a thioether bond, -S-.','2013-10-27','NSRP'),(10869,16803,'ether hydrolase activity','F','Catalysis of the hydrolysis of an ether bond, -O-.','2013-10-27','NSRP'),(10870,16804,'prolyl aminopeptidase activity','F','OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide.','2013-10-27','NSRP'),(10871,16805,'dipeptidase activity','F','Catalysis of the hydrolysis of a dipeptide.','2013-10-27','NSRP'),(10872,16806,'dipeptidyl-peptidase and tripeptidyl-peptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain.','2013-10-27','NSRP'),(10873,16807,'cysteine-type carboxypeptidase activity','F','Catalysis of the hydrolysis of C-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.','2013-10-27','NSRP'),(10874,16808,'proprotein convertase activity','F','OBSOLETE. Was not defined before being made obsolete.','2013-10-27','NSRP'),(10875,16810,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds','F','Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.','2013-10-27','NSRP'),(10876,16811,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides','F','Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.','2013-10-27','NSRP'),(10877,16812,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides','F','Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.','2013-10-27','NSRP'),(10878,16813,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines','F','Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.','2013-10-27','NSRP'),(10879,16814,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines','F','Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.','2013-10-27','NSRP'),(10880,16815,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles','F','Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.','2013-10-27','NSRP'),(10881,16816,'hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds','F','OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.','2013-10-27','NSRP'),(10882,16817,'hydrolase activity, acting on acid anhydrides','F','Catalysis of the hydrolysis of any acid anhydride.','2013-10-27','NSRP'),(10883,16818,'hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides','F','Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.','2013-10-27','NSRP'),(10884,16819,'hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides','F','Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.','2013-10-27','NSRP'),(10885,16820,'hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances','F','Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane.','2013-10-27','NSRP'),(10886,16821,'hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10887,16822,'hydrolase activity, acting on acid carbon-carbon bonds','F','Catalysis of the hydrolysis of any acid carbon-carbon bond.','2013-10-27','NSRP'),(10888,16823,'hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances','F','Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.','2013-10-27','NSRP'),(10889,16824,'hydrolase activity, acting on acid halide bonds','F','Catalysis of the hydrolysis of any acid halide bond.','2013-10-27','NSRP'),(10890,16825,'hydrolase activity, acting on acid phosphorus-nitrogen bonds','F','Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond.','2013-10-27','NSRP'),(10891,16826,'hydrolase activity, acting on acid sulfur-nitrogen bonds','F','Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.','2013-10-27','NSRP'),(10892,16827,'hydrolase activity, acting on acid carbon-phosphorus bonds','F','Catalysis of the hydrolysis of any acid carbon-phosphorus bond.','2013-10-27','NSRP'),(10893,16828,'hydrolase activity, acting on acid sulfur-sulfur bonds','F','Catalysis of the hydrolysis of any acid sulfur-sulfur bond.','2013-10-27','NSRP'),(10894,16829,'lyase activity','F','Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.','2013-10-27','NSRP'),(10895,16830,'carbon-carbon lyase activity','F','Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.','2013-10-27','NSRP'),(10896,16831,'carboxy-lyase activity','F','Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.','2013-10-27','NSRP'),(10897,16832,'aldehyde-lyase activity','F','Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.','2013-10-27','NSRP'),(10898,16833,'oxo-acid-lyase activity','F','Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.','2013-10-27','NSRP'),(10899,16834,'other carbon-carbon lyase activity','F','OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10900,16835,'carbon-oxygen lyase activity','F','Catalysis of the breakage of a carbon-oxygen bond.','2013-10-27','NSRP'),(10901,16836,'hydro-lyase activity','F','Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.','2013-10-27','NSRP'),(10902,16837,'carbon-oxygen lyase activity, acting on polysaccharides','F','Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.','2013-10-27','NSRP'),(10903,16838,'carbon-oxygen lyase activity, acting on phosphates','F','Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.','2013-10-27','NSRP'),(10904,16839,'other carbon-oxygen lyase activity','F','OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are \'miscellaneous\' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.','2013-10-27','NSRP'),(10905,16840,'carbon-nitrogen lyase activity','F','Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).','2013-10-27','NSRP'),(10906,16841,'ammonia-lyase activity','F','Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.','2013-10-27','NSRP'),(10907,16842,'amidine-lyase activity','F','Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.','2013-10-27','NSRP'),(10908,16843,'amine-lyase activity','F','Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.','2013-10-27','NSRP'),(10909,16844,'strictosidine synthase activity','F','Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine.','2013-10-27','NSRP'),(10910,16845,'other carbon-nitrogen lyase activity','F','OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are \'miscellaneous\' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.','2013-10-27','NSRP'),(10911,16846,'carbon-sulfur lyase activity','F','Catalysis of the elimination of hydrogen sulfide or substituted H2S.','2013-10-27','NSRP'),(10912,16847,'1-aminocyclopropane-1-carboxylate synthase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5\'-thioadenosine + H(+).','2013-10-27','NSRP'),(10913,16848,'carbon-halide lyase activity','F','Catalysis of the breakage of a bond between carbon and any halogen atom.','2013-10-27','NSRP'),(10914,16849,'phosphorus-oxygen lyase activity','F','Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.','2013-10-27','NSRP'),(10915,16850,'other lyase activity','F','OBSOLETE. A grouping term for lyases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10916,16851,'magnesium chelatase activity','F','Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate.','2013-10-27','NSRP'),(10917,16852,'sirohydrochlorin cobaltochelatase activity','F','Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.','2013-10-27','NSRP'),(10918,16853,'isomerase activity','F','Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.','2013-10-27','NSRP'),(10919,16854,'racemase and epimerase activity','F','Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.','2013-10-27','NSRP'),(10920,16855,'racemase and epimerase activity, acting on amino acids and derivatives','F','Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.','2013-10-27','NSRP'),(10921,16856,'racemase and epimerase activity, acting on hydroxy acids and derivatives','F','Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.','2013-10-27','NSRP'),(10922,16857,'racemase and epimerase activity, acting on carbohydrates and derivatives','F','Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.','2013-10-27','NSRP'),(10923,16858,'racemase and epimerase activity, acting on other compounds','F','OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.','2013-10-27','NSRP'),(10924,16859,'cis-trans isomerase activity','F','Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.','2013-10-27','NSRP'),(10925,16860,'intramolecular oxidoreductase activity','F','Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.','2013-10-27','NSRP'),(10926,16861,'intramolecular oxidoreductase activity, interconverting aldoses and ketoses','F','Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.','2013-10-27','NSRP'),(10927,16862,'intramolecular oxidoreductase activity, interconverting keto- and enol-groups','F','Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.','2013-10-27','NSRP'),(10928,16863,'intramolecular oxidoreductase activity, transposing C=C bonds','F','Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.','2013-10-27','NSRP'),(10929,16864,'intramolecular oxidoreductase activity, transposing S-S bonds','F','Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.','2013-10-27','NSRP'),(10930,16865,'intramolecular oxidoreductase activity, other intramolecular oxidoreductases','F','OBSOLETE. A grouping term for intramolecular oxidoreductases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10931,16866,'intramolecular transferase activity','F','Catalysis of the transfer of a functional group from one position to another within a single molecule.','2013-10-27','NSRP'),(10932,16867,'intramolecular transferase activity, transferring acyl groups','F','Catalysis of the transfer of an acyl group from one position to another within a single molecule.','2013-10-27','NSRP'),(10933,16868,'intramolecular transferase activity, phosphotransferases','F','Catalysis of the transfer of a phosphate group from one position to another within a single molecule.','2013-10-27','NSRP'),(10934,16869,'intramolecular transferase activity, transferring amino groups','F','Catalysis of the transfer of an amino group from one position to another within a single molecule.','2013-10-27','NSRP'),(10935,16870,'intramolecular transferase activity, transferring other groups','F','OBSOLETE. A grouping term for intramolecular transferases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10936,16871,'cycloartenol synthase activity','F','Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.','2013-10-27','NSRP'),(10937,16872,'intramolecular lyase activity','F','The catalysis of certain rearrangements of a molecule to break or form a ring.','2013-10-27','NSRP'),(10938,16873,'other isomerase activity','F','OBSOLETE. A grouping term for isomerases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10939,16874,'ligase activity','F','Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10940,16875,'ligase activity, forming carbon-oxygen bonds','F','Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10941,16876,'ligase activity, forming aminoacyl-tRNA and related compounds','F','Catalysis of the joining of an amino acid and a nucleic acid (usually tRNA) or poly(ribitol phosphate), with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. The reaction forms an aminoacyl-tRNA or a related compound.','2013-10-27','NSRP'),(10942,16877,'ligase activity, forming carbon-sulfur bonds','F','Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10943,16878,'acid-thiol ligase activity','F','Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10944,16879,'ligase activity, forming carbon-nitrogen bonds','F','Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10945,16880,'acid-ammonia (or amide) ligase activity','F','Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10946,16881,'acid-amino acid ligase activity','F','Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10947,16882,'cyclo-ligase activity','F','Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10948,16883,'other carbon-nitrogen ligase activity','F','OBSOLETE. A grouping term for carbon-nitrogen ligases that cannot be more accurately categorized.','2013-10-27','NSRP'),(10949,16884,'carbon-nitrogen ligase activity, with glutamine as amido-N-donor','F','Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.','2013-10-27','NSRP'),(10950,16885,'ligase activity, forming carbon-carbon bonds','F','Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10951,16886,'ligase activity, forming phosphoric ester bonds','F','Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.','2013-10-27','NSRP'),(10952,16887,'ATPase activity','F','Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.','2013-10-27','NSRP'),(10953,16888,'endodeoxyribonuclease activity, producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5\'-phosphomonoesters.','2013-10-27','NSRP'),(10954,16889,'endodeoxyribonuclease activity, producing 3\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3\'-phosphomonoesters.','2013-10-27','NSRP'),(10955,16890,'site-specific endodeoxyribonuclease activity, specific for altered base','F','Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.','2013-10-27','NSRP'),(10956,16891,'endoribonuclease activity, producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5\'-phosphomonoesters.','2013-10-27','NSRP'),(10957,16892,'endoribonuclease activity, producing 3\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3\'-phosphomonoesters.','2013-10-27','NSRP'),(10958,16893,'endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5\'-phosphomonoesters.','2013-10-27','NSRP'),(10959,16894,'endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3\'-phosphomonoesters.','2013-10-27','NSRP'),(10960,16895,'exodeoxyribonuclease activity, producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3\' or 5\' end to yield 5\' phosphomonoesters.','2013-10-27','NSRP'),(10961,16896,'exoribonuclease activity, producing 5\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3\' or 5\' end to yield 5\' phosphomonoesters.','2013-10-27','NSRP'),(10962,16897,'exoribonuclease activity, producing 3\'-phosphomonoesters','F','Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3\' or 5\' end to yield 3\' phosphomonoesters.','2013-10-27','NSRP'),(10963,16898,'oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.','2013-10-27','NSRP'),(10964,16899,'oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.','2013-10-27','NSRP'),(10965,16900,'oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule.','2013-10-27','NSRP'),(10966,16901,'oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor','F','Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.','2013-10-27','NSRP'),(10967,16902,'oxidoreductase activity, acting on the CH-OH group of donors, other acceptors','F','OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an acceptor other than a cytochrome, disulfide, NAD, NADP, oxygen or a quinone or similar compound.','2013-10-27','NSRP'),(10968,16903,'oxidoreductase activity, acting on the aldehyde or oxo group of donors','F','Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.','2013-10-27','NSRP'),(10969,16905,'myosin heavy chain kinase activity','F','Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.','2013-10-27','NSRP'),(10970,16906,'sterol 3-beta-glucosyltransferase activity','F','Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.','2013-10-27','NSRP'),(10971,16907,'G-protein coupled acetylcholine receptor activity','F','Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.','2013-10-27','NSRP'),(10972,16909,'SAP kinase activity','F','Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.','2013-10-27','NSRP'),(10973,16910,'SAP kinase 3 activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10974,16911,'SAP kinase 4 activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10975,16912,'SAP kinase 5 activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(10976,16913,'follicle-stimulating hormone activity','F','The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.','2013-10-27','NSRP'),(10977,16914,'follicle-stimulating hormone complex','C','A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.','2013-10-27','NSRP'),(10978,16915,'activin','F','OBSOLETE. A nonsteroidal regulator, composed of two covalently linked beta subunits, that is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.','2013-10-27','NSRP'),(10979,16916,'inhibin','F','OBSOLETE. Either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.','2013-10-27','NSRP'),(10980,16917,'GABA receptor activity','F','Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.','2013-10-27','NSRP'),(10981,16918,'retinal binding','F','Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.','2013-10-27','NSRP'),(10982,16919,'nardilysin activity','F','OBSOLETE. Catalysis of the hydrolysis of polypeptides, preferably at the first bond of Xaa-Arg-Lys, and less commonly at the first bond of Arg-Arg-Xaa, in which Xaa is not Arg or Lys.','2013-10-27','NSRP'),(10983,16920,'pyroglutamyl-peptidase activity','F','Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.','2013-10-27','NSRP'),(10984,16921,'pyroglutamyl-peptidase II activity','F','OBSOLETE. Catalysis of the release of the N-terminal pyroglutamyl group from pGlu-His-Xaa tripeptides and pGlu-His-Xaa-Gly tetrapeptides.','2013-10-27','NSRP'),(10985,16922,'ligand-dependent nuclear receptor binding','F','Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.','2013-10-27','NSRP'),(10986,16923,'ligand-dependent thyroid hormone receptor interactor activity','F','OBSOLETE. Ligand dependent interaction with the thyroid hormone receptor.','2013-10-27','NSRP'),(10987,16925,'protein sumoylation','P','The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.','2013-10-27','NSRP'),(10988,16926,'protein desumoylation','P','The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.','2013-10-27','NSRP'),(10989,16929,'SUMO-specific protease activity','F','Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates.','2013-10-27','NSRP'),(10990,16933,'extracellular-glycine-gated ion channel activity','F','Catalysis of the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(10991,16934,'extracellular-glycine-gated chloride channel activity','F','Catalysis of the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(10992,16935,'glycine-gated chloride channel complex','C','A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(10993,16936,'galactoside binding','F','Interacting selectively and non-covalently with any glycoside in which the sugar group is galactose.','2013-10-27','NSRP'),(10994,16937,'short-branched-chain-acyl-CoA dehydrogenase activity','F','Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue.','2013-10-27','NSRP'),(10995,16938,'kinesin I complex','C','A complex of two kinesin heavy chains and two kinesin light chains.','2013-10-27','NSRP'),(10996,16939,'kinesin II complex','C','A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.','2013-10-27','NSRP'),(10997,16941,'natriuretic peptide receptor activity','F','Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.','2013-10-27','NSRP'),(10998,16942,'insulin-like growth factor binding protein complex','C','A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.','2013-10-27','NSRP'),(10999,16943,'RNA polymerase I transcription elongation factor activity','F','OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase I following transcription initiation.','2013-10-27','NSRP'),(11000,16944,'RNA polymerase II transcription elongation factor activity','F','OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase II following transcription initiation.','2013-10-27','NSRP'),(11001,16945,'RNA polymerase III transcription elongation factor activity','F','OBSOLETE. Any activity that modulates the rate of transcription elongation, the addition of ribonucleotides to an RNA molecule catalyzed by RNA polymerase III following transcription initiation.','2013-10-27','NSRP'),(11002,16946,'cathepsin F activity','F','OBSOLETE. Catalysis of the hydrolysis of peptide bonds. Cleavage of substrates with Phe and Leu in P2.','2013-10-27','NSRP'),(11003,16962,'receptor-associated protein activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11004,16963,'alpha-2 macroglobulin receptor-associated protein activity','F','OBSOLETE. Interaction with the alpha-2 macroglobulin receptor and glycoprotein gp330 forming a complex with the alpha-2 macroglobulin receptor light and heavy chains.','2013-10-27','NSRP'),(11005,16964,'alpha-2 macroglobulin receptor activity','F','Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.','2013-10-27','NSRP'),(11006,16966,'nitric oxide reductase activity','F','Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.','2013-10-27','NSRP'),(11007,16969,'hemerythrin','F','OBSOLETE. An oxygen carrier found in a few groups of invertebrates, e.g. sipunculid worms, certain molluscs, and crustaceans.','2013-10-27','NSRP'),(11008,16970,'hemocyanin','F','OBSOLETE. A blue, copper-containing oxygen carrier present in many molluscs and arthropods.','2013-10-27','NSRP'),(11009,16971,'flavin-linked sulfhydryl oxidase activity','F','Catalysis of the formation of disulfide bridges.','2013-10-27','NSRP'),(11010,16972,'thiol oxidase activity','F','Catalysis of the reaction: 4 R\'C(R)SH + O2 = 2 R\'C(R)S-S(R)CR\' + 2 H2O.','2013-10-27','NSRP'),(11011,16973,'poly(A)+ mRNA export from nucleus','P','The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.','2013-10-27','NSRP'),(11012,16975,'alpha-2 macroglobulin','F','OBSOLETE. Inhibition of proteinase by a mechanism involving a bait region which contains specific sites, cleavage of which induces a conformational change that results in trapping of the proteinase; following cleavage in the bait region a thiolester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase; subsequently epsilon-amino groups of the proteinase react with thiolester linkages in the inhibitor to form stable amide links; the entrapped proteinase can now only act on low molecular mass substrates.','2013-10-27','NSRP'),(11013,16977,'chitosanase activity','F','Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.','2013-10-27','NSRP'),(11014,16979,'lipoate-protein ligase activity','F','Catalysis of the formation of carbon-nitrogen bonds between lipoate (5-(1,2-dithiolan-3-yl)pentanoate) and a protein.','2013-10-27','NSRP'),(11015,16980,'creatinase activity','F','Catalysis of the reaction: creatine + H(2)O = sarcosine + urea.','2013-10-27','NSRP'),(11016,16984,'ribulose-bisphosphate carboxylase activity','F','Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate.','2013-10-27','NSRP'),(11017,16985,'mannan endo-1,4-beta-mannosidase activity','F','Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.','2013-10-27','NSRP'),(11018,16986,'transcription initiation factor activity','F','OBSOLETE. Plays a role in regulating transcription initiation.','2013-10-27','NSRP'),(11019,16987,'sigma factor activity','F','A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promoter elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes.','2013-10-27','NSRP'),(11020,16988,'transcription initiation factor antagonist activity','F','OBSOLETE. The function of binding to a transcription factor and stopping, preventing or reducing the rate of its transcriptional activity.','2013-10-27','NSRP'),(11021,16989,'sigma factor antagonist activity','F','The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.','2013-10-27','NSRP'),(11022,16990,'arginine deiminase activity','F','Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.','2013-10-27','NSRP'),(11023,16992,'lipoate synthase activity','F','Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5\'-deoxyadenosyl.','2013-10-27','NSRP'),(11024,16993,'precorrin-8X methylmutase activity','F','Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.','2013-10-27','NSRP'),(11025,16994,'precorrin-6A reductase activity','F','Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.','2013-10-27','NSRP'),(11026,16995,'cholesterol oxidase activity','F','Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.','2013-10-27','NSRP'),(11027,16996,'endo-alpha-(2,8)-sialidase activity','F','Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.','2013-10-27','NSRP'),(11028,16997,'alpha-sialidase activity','F','Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.','2013-10-27','NSRP'),(11029,16998,'cell wall macromolecule catabolic process','P','The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.','2013-10-27','NSRP'),(11030,16999,'antibiotic metabolic process','P','The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.','2013-10-27','NSRP'),(11031,17000,'antibiotic biosynthetic process','P','The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.','2013-10-27','NSRP'),(11032,17001,'antibiotic catabolic process','P','The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.','2013-10-27','NSRP'),(11033,17002,'activin-activated receptor activity','F','Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.','2013-10-27','NSRP'),(11034,17003,'protein-heme linkage','P','The covalent linkage of heme and a protein.','2013-10-27','NSRP'),(11035,17004,'cytochrome complex assembly','P','The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.','2013-10-27','NSRP'),(11036,17005,'3\'-tyrosyl-DNA phosphodiesterase activity','F','Catalysis of the hydrolysis of 3\'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.','2013-10-27','NSRP'),(11037,17006,'protein-tetrapyrrole linkage','P','The covalent linking of a tetrapyrrole to a protein.','2013-10-27','NSRP'),(11038,17007,'protein-bilin linkage','P','The covalent linkage of bilin and a protein.','2013-10-27','NSRP'),(11039,17008,'protein-phycobiliviolin linkage','P','The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.','2013-10-27','NSRP'),(11040,17009,'protein-phycocyanobilin linkage','P','The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.','2013-10-27','NSRP'),(11041,17010,'protein-phycourobilin linkage','P','The linkage of the chromophore phycourobilin to phycoerythrins.','2013-10-27','NSRP'),(11042,17011,'protein-phycoerythrobilin linkage','P','The linkage of the chromophore phycoerythrobilin to phycoerythrins.','2013-10-27','NSRP'),(11043,17012,'protein-phytochromobilin linkage','P','The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.','2013-10-27','NSRP'),(11044,17013,'protein flavinylation','P','The addition of a flavin group to a protein amino acid.','2013-10-27','NSRP'),(11045,17014,'protein nitrosylation','P','The covalent addition of a nitric oxide group to an amino acid within a protein.','2013-10-27','NSRP'),(11046,17015,'regulation of transforming growth factor beta receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.','2013-10-27','NSRP'),(11047,17016,'Ras GTPase binding','F','Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.','2013-10-27','NSRP'),(11048,17017,'MAP kinase tyrosine/serine/threonine phosphatase activity','F','Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.','2013-10-27','NSRP'),(11049,17018,'myosin phosphatase activity','F','Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.','2013-10-27','NSRP'),(11050,17020,'myosin phosphatase regulator activity','F','Modulation of the activity of the enzyme myosin phosphatase.','2013-10-27','NSRP'),(11051,17021,'myosin phosphatase myosin binding','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11052,17022,'myosin binding','F','Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.','2013-10-27','NSRP'),(11053,17023,'myosin phosphatase complex','C','An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin.','2013-10-27','NSRP'),(11054,17024,'myosin I binding','F','Interacting selectively and non-covalently with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.','2013-10-27','NSRP'),(11055,17025,'TBP-class protein binding','F','Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).','2013-10-27','NSRP'),(11056,17026,'procollagen C-endopeptidase activity','F','OBSOLETE. Catalysis of the cleavage of the C-terminal propeptide at Ala-Asp in type I and II procollagens and at Arg-Asp in type III.','2013-10-27','NSRP'),(11057,17027,'transmembrane receptor protein serine/threonine kinase receptor-associated protein activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11058,17028,'protein stabilization activity','F','OBSOLETE. Strengthening of a bond between proteins. Proteins are large molecules composed of one or more chains of amino acids. The amino acids are joined in a specific order by peptide bonds.','2013-10-27','NSRP'),(11059,17029,'lysosomal protein stabilization','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11060,17030,'beta-galactosidase stabilization activity','F','OBSOLETE. Stabilization of the structure of beta-galactosidase.','2013-10-27','NSRP'),(11061,17032,'potassium:amino acid symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).','2013-10-27','NSRP'),(11062,17033,'DNA topoisomerase I binding','F','Interacting selectively and non-covalently with the enzyme DNA topoisomerase I.','2012-03-14','NSRP'),(11063,17034,'Rap guanyl-nucleotide exchange factor activity','F','Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rap family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.','2013-10-27','NSRP'),(11064,17038,'protein import','P','The directed movement of proteins into a cell or organelle.','2013-10-27','NSRP'),(11065,17039,'dipeptidyl-peptidase III activity','F','OBSOLETE. Catalysis of the release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity; also acts on dipeptidyl 2-naphthylamides.','2013-10-27','NSRP'),(11066,17040,'ceramidase activity','F','Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.','2013-10-27','NSRP'),(11067,17041,'galactosylgalactosylglucosylceramidase activity','F','Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose.','2013-10-27','NSRP'),(11068,17042,'glycosylceramidase activity','F','Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.','2013-10-27','NSRP'),(11069,17043,'adrenocorticotropin','F','OBSOLETE. A polypeptide hormone which stimulates the adrenal cortex to synthesize and secrete glucocorticoid hormones.','2013-10-27','NSRP'),(11070,17044,'melanocyte-stimulating hormone activity','F','The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.','2013-10-27','NSRP'),(11071,17045,'corticotropin-releasing hormone activity','F','The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.','2013-10-27','NSRP'),(11072,17046,'peptide hormone binding','F','Interacting selectively and non-covalently with any peptide with hormonal activity in animals.','2013-10-27','NSRP'),(11073,17048,'Rho GTPase binding','F','Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.','2013-10-27','NSRP'),(11074,17049,'GTP-Rho binding','F','Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.','2013-10-27','NSRP'),(11075,17050,'D-erythro-sphingosine kinase activity','F','Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.','2013-10-27','NSRP'),(11076,17051,'retinol dehydratase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + retinol = adenosine 3\',5\'-bisphosphate + anhydroretinol.','2013-10-27','NSRP'),(11077,17052,'insulin-like growth factor binding protein','C','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11078,17053,'transcriptional repressor complex','C','A protein complex that possesses activity that prevents or downregulates transcription.','2013-10-27','NSRP'),(11079,17054,'negative cofactor 2 complex','C','A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.','2013-10-27','NSRP'),(11080,17055,'negative regulation of RNA polymerase II transcriptional preinitiation complex assembly','P','Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.','2013-10-27','NSRP'),(11081,17056,'structural constituent of nuclear pore','F','The action of a molecule that contributes to the structural integrity of the nuclear pore complex.','2013-10-27','NSRP'),(11082,17057,'6-phosphogluconolactonase activity','F','Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+).','2013-10-27','NSRP'),(11083,17058,'FH1 domain binding','F','Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.','2013-10-27','NSRP'),(11084,17059,'serine C-palmitoyltransferase complex','C','An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.','2013-10-27','NSRP'),(11085,17060,'3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity','F','Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.','2013-10-27','NSRP'),(11086,17061,'S-methyl-5-thioadenosine phosphorylase activity','F','Catalysis of the reaction: 5\'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.','2013-10-27','NSRP'),(11087,17062,'respiratory chain complex III assembly','P','The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.','2013-10-27','NSRP'),(11088,17063,'phosphatidylserine-specific phospholipase A1 activity','F','OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a fatty acid anion.','2013-10-27','NSRP'),(11089,17064,'fatty acid amide hydrolase activity','F','Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.','2013-10-27','NSRP'),(11090,17065,'single-strand selective uracil DNA N-glycosylase activity','F','Catalysis of the cleavage of the N-C1\' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.','2013-10-27','NSRP'),(11091,17067,'tyrosine-ester sulfotransferase activity','F','Catalysis of the reaction: 3\'-phospho-5\'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3\',5\'-diphosphate + H(+).','2013-10-27','NSRP'),(11092,17069,'snRNA binding','F','Interacting selectively and non-covalently with a small nuclear RNA (snRNA).','2013-10-27','NSRP'),(11093,17070,'U6 snRNA binding','F','Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA).','2013-10-27','NSRP'),(11094,17071,'intracellular cyclic nucleotide activated cation channel complex','C','A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.','2013-10-27','NSRP'),(11095,17072,'tubulin-specific chaperone activity','F','OBSOLETE. Assists in the correct, non-covalent assembly of tubulin-containing structures in vivo, but is not a component of the assembled structures when performing its normal biological function.','2013-10-27','NSRP'),(11096,17074,'procollagen N-endopeptidase activity','F','OBSOLETE. Catalysis of the cleavage of the N-propeptide of collagen chain alpha-1(I) at Pro-Gln and of alpha-1(II) and alpha-2(I) chains at Ala-Gln.','2013-10-27','NSRP'),(11097,17075,'syntaxin-1 binding','F','Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.','2013-10-27','NSRP'),(11098,17076,'purine nucleotide binding','F','Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.','2013-10-27','NSRP'),(11099,17077,'oxidative phosphorylation uncoupler activity','F','Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.','2013-10-27','NSRP'),(11100,17078,'Hsc70 protein regulator activity','F','OBSOLETE. Binds to and modulates the activity of the molecular chaperone Hsc70.','2013-10-27','NSRP'),(11101,17080,'sodium channel regulator activity','F','Modulates the activity of a sodium channel.','2013-10-27','NSRP'),(11102,17081,'chloride channel regulator activity','F','Modulates the activity of a chloride channel.','2013-10-27','NSRP'),(11103,17082,'mineralocorticoid receptor activity','F','Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.','2013-10-27','NSRP'),(11104,17083,'4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity','F','Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.','2013-10-27','NSRP'),(11105,17084,'delta1-pyrroline-5-carboxylate synthetase activity','F','Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.','2013-10-27','NSRP'),(11106,17085,'response to insecticide','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.','2013-10-27','NSRP'),(11107,17086,'3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex','C','A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate.','2013-10-27','NSRP'),(11108,17087,'mitochondrial processing peptidase complex','C','A protein complex that consists of a catalytic alpha subunit (alpha-MPP) and a regulatory beta subunit (beta-MPP), and catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.','2013-10-27','NSRP'),(11109,17088,'X-Pro dipeptidyl-peptidase activity','F','OBSOLETE. Catalysis of the hydrolysis of the terminal bond of Xaa-Pro-Xaa motifs to release unblocked, N-terminal dipeptides from substrates including Ala-Pro-para-nitroanilide and (sequentially, at the second, fourth and sixth bonds) of the motif Tyr-Pro-Phe-Pro-Gly-Pro-Ile.','2013-10-27','NSRP'),(11110,17089,'glycolipid transporter activity','F','Enables the directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells.','2013-10-27','NSRP'),(11111,17090,'meprin A complex','C','A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.','2013-10-27','NSRP'),(11112,17091,'AU-rich element binding','F','Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.','2013-10-27','NSRP'),(11113,17092,'sterol regulatory element-binding protein site 2 protease activity','F','OBSOLETE. Catalysis of the cleavage, within the membrane-spanning helix, of the amino-terminal half (the intermediate form) of sterol regulatory element binding protein (SREBP). This activity releases the transcription factor domain of SREBP from the membrane, freeing it to enter the nucleus.','2013-10-27','NSRP'),(11114,17093,'sterol regulatory element-binding protein protease activity','F','OBSOLETE. Catalysis of the hydrolysis of peptide bonds within a sterol regulatory element binding protein (SREBP). SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.','2013-10-27','NSRP'),(11115,17094,'sterol regulatory element-binding protein site 1 protease activity','F','OBSOLETE. Catalysis of the cleavage of a Leu-Ser bond within the luminal loop of a sterol regulatory element binding protein (SREBP). This activity is the first of two sequential cleavage reactions and cleaves SREBP into two membrane-bound halves.','2013-10-27','NSRP'),(11116,17095,'heparan sulfate 6-O-sulfotransferase activity','F','Catalysis of the reaction: 3\'-phosphoadenosine 5\'-phosphosulfate + heparan sulfate = adenosine 3\',5\'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.','2013-10-27','NSRP'),(11117,17096,'acetylserotonin O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.','2013-10-27','NSRP'),(11118,17098,'sulfonylurea receptor binding','F','Interacting selectively and non-covalently with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.','2013-10-27','NSRP'),(11119,17099,'very-long-chain-acyl-CoA dehydrogenase activity','F','Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.','2013-10-27','NSRP'),(11120,17101,'aminoacyl-tRNA synthetase multienzyme complex','C','A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2\'- or 3\'-hydroxyl of the 3\'-terminal adenosine of tRNA, but using different substrates.','2013-10-27','NSRP'),(11121,17102,'methionyl glutamyl tRNA synthetase complex','C','A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.','2013-10-27','NSRP'),(11122,17103,'UTP:galactose-1-phosphate uridylyltransferase activity','F','Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.','2013-10-27','NSRP'),(11123,17105,'acyl-CoA delta11-desaturase activity','F','Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O.','2013-10-27','NSRP'),(11124,17106,'activin inhibitor activity','F','OBSOLETE. Acts to negatively regulate the activity of activin, a nonsteroidal regulator synthesized in the pituitary gland and gonads that stimulates the secretion of follicle-stimulating hormone.','2013-10-27','NSRP'),(11125,17107,'anion exchanger adaptor activity','F','The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way.','2013-10-27','NSRP'),(11126,17108,'5\'-flap endonuclease activity','F','Catalysis of the cleavage of a 5\' flap structure in DNA, but not other DNA structures; processes the 5\' ends of Okazaki fragments in lagging strand DNA synthesis.','2013-10-27','NSRP'),(11127,17109,'glutamate-cysteine ligase complex','C','An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.','2013-10-27','NSRP'),(11128,17110,'nucleoside-diphosphatase activity','F','Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.','2013-10-27','NSRP'),(11129,17111,'nucleoside-triphosphatase activity','F','Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.','2013-10-27','NSRP'),(11130,17112,'Rab guanyl-nucleotide exchange factor activity','F','Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.','2013-10-27','NSRP'),(11131,17113,'dihydropyrimidine dehydrogenase (NADP+) activity','F','Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.','2013-10-27','NSRP'),(11132,17114,'wide-spectrum protease inhibitor activity','F','OBSOLETE. Stops, prevents or reduces the activity of a protease by a wide-spectrum protease inhibitor. A wide-spectrum protease inhibitor is a protein having a peptide stretch which contains specific cleavage sites for different proteinases enabling inhibition of all four classes of proteinases by formation of a covalent bond between the inhibitor and the protease.','2013-10-27','NSRP'),(11133,17116,'single-stranded DNA-dependent ATP-dependent DNA helicase activity','F','Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.','2013-10-27','NSRP'),(11134,17117,'single-stranded DNA-dependent ATP-dependent DNA helicase complex','C','A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.','2013-10-27','NSRP'),(11135,17118,'lipoyltransferase activity','F','Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme.','2013-10-27','NSRP'),(11136,17119,'Golgi transport complex','C','A complex of proteins that, in vitro, stimulates intra-Golgi transport; a 13S complex, about 800 kDa in size and consists of at least five polypeptides. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p).','2013-10-27','NSRP'),(11137,17120,'polyphosphatidylinositol phosphatase activity','F','OBSOLETE. Catalysis of the conversion of phosphatidylinositol-3-phosphate, phosphatidylinositol-4-phosphate, and phosphatidylinositol-3,5-bisphosphate, but not PI-4,5-bisphosphate, to phosphatidylinositol; PPIPase activity is a key regulator of membrane trafficking and actin cytoskeleton organization.','2013-10-27','NSRP'),(11138,17121,'phospholipid scrambling','P','The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).','2013-10-27','NSRP'),(11139,17122,'protein N-acetylglucosaminyltransferase complex','C','Heterotrimeric enzyme complex, which in humans is composed of two large subunits of the same size, and one smaller subunit. Functions in the addition of nucleotide-activated sugars onto the polypeptide.','2013-10-27','NSRP'),(11140,17123,'Ral GTPase activator activity','F','Increases the rate of GTP hydrolysis by a GTPase of the Ral family.','2013-10-27','NSRP'),(11141,17124,'SH3 domain binding','F','Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.','2013-10-27','NSRP'),(11142,17125,'deoxycytidyl transferase activity','F','Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.','2013-10-27','NSRP'),(11143,17126,'nucleologenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.','2013-10-27','NSRP'),(11144,17127,'cholesterol transporter activity','F','Enables the directed movement of cholesterol into, out of or within a cell, or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.','2013-10-27','NSRP'),(11145,17128,'phospholipid scramblase activity','F','Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.','2013-10-27','NSRP'),(11146,17129,'triglyceride binding','F','Interacting selectively and non-covalently with any triester of glycerol.','2013-10-27','NSRP'),(11147,17130,'poly(C) RNA binding','F','Interacting selectively and non-covalently with a sequence of cytosine residues in an RNA molecule.','2013-10-27','NSRP'),(11148,17131,'uridine-rich cytoplasmic polyadenylylation element binding','F','Interacting selectively and non-covalently with U-rich sequence in the 3\'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.','2013-10-27','NSRP'),(11149,17132,'cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity','F','Stimulates the exchange of guanyl nucleotides associated with a GTPase; dependent on the presence of a cyclic nucleotide.','2013-10-27','NSRP'),(11150,17133,'mitochondrial electron transfer flavoprotein complex','C','A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.','2013-10-27','NSRP'),(11151,17134,'fibroblast growth factor binding','F','Interacting selectively and non-covalently with a fibroblast growth factor.','2013-10-27','NSRP'),(11152,17135,'membrane-associated protein with guanylate kinase activity interacting','F','OBSOLETE. The interaction with synapse-associated membrane-associated protein with guanylate kinase activity.','2013-10-27','NSRP'),(11153,17136,'NAD-dependent histone deacetylase activity','F','Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.','2013-10-27','NSRP'),(11154,17137,'Rab GTPase binding','F','Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.','2013-10-27','NSRP'),(11155,17139,'arsenate sensitivity/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11156,17141,'antibiotic susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11157,17142,'toxin susceptibility/resistance','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11158,17143,'insecticide metabolic process','P','The chemical reactions and pathways involving insecticides, chemicals used to kill insects.','2013-10-27','NSRP'),(11159,17144,'drug metabolic process','P','The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.','2013-10-27','NSRP'),(11160,17145,'stem cell division','P','The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.','2013-10-27','NSRP'),(11161,17146,'N-methyl-D-aspartate selective glutamate receptor complex','C','An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.','2013-10-27','NSRP'),(11162,17147,'Wnt-protein binding','F','Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling.','2013-10-27','NSRP'),(11163,17148,'negative regulation of translation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.','2013-10-27','NSRP'),(11164,17149,'protein biosynthetic process inhibitor activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11165,17150,'tRNA dihydrouridine synthase activity','F','Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.','2013-10-27','NSRP'),(11166,17151,'DEAD/H-box RNA helicase binding','F','Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.','2013-10-27','NSRP'),(11167,17153,'sodium:dicarboxylate symporter activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).','2013-10-27','NSRP'),(11168,17154,'semaphorin receptor activity','F','Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(11169,17155,'sodium:hydrogen antiporter regulator activity','F','OBSOLETE.','2013-10-27','NSRP'),(11170,17156,'calcium ion-dependent exocytosis','P','The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, requiring the presence of calcium ions.','2013-10-27','NSRP'),(11171,17157,'regulation of exocytosis','P','Any process that modulates the frequency, rate or extent of exocytosis.','2013-10-27','NSRP'),(11172,17158,'regulation of calcium ion-dependent exocytosis','P','Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.','2013-10-27','NSRP'),(11173,17159,'pantetheine hydrolase activity','F','Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine.','2013-10-27','NSRP'),(11174,17160,'Ral GTPase binding','F','Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases.','2013-10-27','NSRP'),(11175,17161,'inositol-1,3,4-trisphosphate 4-phosphatase activity','F','Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.','2013-10-27','NSRP'),(11176,17162,'aryl hydrocarbon receptor binding','F','Interacting selectively and non-covalently with an aryl hydrocarbon receptor.','2013-10-27','NSRP'),(11177,17163,'basal transcription repressor activity','F','OBSOLETE. Any transcription regulator activity that prevents or downregulates basal transcription. Basal transcription results from transcription that is controlled by the minimal complement of proteins necessary to reconstitute transcription from a minimal promoter.','2013-10-27','NSRP'),(11178,17164,'nicotinic acetylcholine receptor-associated protein activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11179,17165,'dipeptidase E activity','F','OBSOLETE. Catalysis of the hydrolysis of dipeptides Asp-Xaa; does not act on peptides with N-terminal Glu, Asn or Gln, nor does it cleave isoaspartyl peptides.','2013-10-27','NSRP'),(11180,17166,'vinculin binding','F','Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.','2013-10-27','NSRP'),(11181,17168,'5-oxoprolinase (ATP-hydrolyzing) activity','F','Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.','2013-10-27','NSRP'),(11182,17169,'CDP-alcohol phosphatidyltransferase activity','F','Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.','2013-10-27','NSRP'),(11183,17170,'KU70 binding','F','OBSOLETE. Interacting selectively and non-covalently with Ku70, a protein involved in non-homologous DNA end joining.','2013-10-27','NSRP'),(11184,17171,'serine hydrolase activity','F','Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).','2013-10-27','NSRP'),(11185,17172,'cysteine dioxygenase activity','F','Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+).','2013-10-27','NSRP'),(11186,17174,'glycine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.','2013-10-27','NSRP'),(11187,17175,'IMP-GMP specific 5\'-nucleotidase activity','F','OBSOLETE. Catalysis of the conversion of 5\'-ribonucleotides to ribonucleosides and phosphate, with specificity for IMP or GMP 5\'-ribonucleotides and H2O as a nucleophile.','2013-10-27','NSRP'),(11188,17176,'phosphatidylinositol N-acetylglucosaminyltransferase activity','F','Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.','2013-10-27','NSRP'),(11189,17177,'glucosidase II complex','C','A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.','2013-10-27','NSRP'),(11190,17178,'diphthine-ammonia ligase activity','F','Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate.','2013-10-27','NSRP'),(11191,17179,'peptidyl-diphthine metabolic process','P','The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue.','2013-10-27','NSRP'),(11192,17180,'peptidyl-diphthine biosynthetic process from peptidyl-histidine','P','The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine.','2013-10-27','NSRP'),(11193,17181,'peptidyl-diphthine catabolic process','P','The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue.','2013-10-27','NSRP'),(11194,17182,'peptidyl-diphthamide metabolic process','P','The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.','2013-10-27','NSRP'),(11195,17183,'peptidyl-diphthamide biosynthetic process from peptidyl-histidine','P','The modification of peptidyl-histidine to 2\'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor eEF-2.','2013-10-27','NSRP'),(11196,17184,'peptidyl-diphthamide catabolic process','P','The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue.','2013-10-27','NSRP'),(11197,17185,'peptidyl-lysine hydroxylation','P','The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.','2013-10-27','NSRP'),(11198,17186,'peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase','P','The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.','2013-10-27','NSRP'),(11199,17187,'peptidyl-glutamic acid carboxylation','P','The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.','2013-10-27','NSRP'),(11200,17188,'aspartate N-acetyltransferase activity','F','Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+).','2013-10-27','NSRP'),(11201,17189,'N-terminal peptidyl-alanine acetylation','P','The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.','2013-10-27','NSRP'),(11202,17190,'N-terminal peptidyl-aspartic acid acetylation','P','The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.','2013-10-27','NSRP'),(11203,17192,'N-terminal peptidyl-glutamine acetylation','P','The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.','2013-10-27','NSRP'),(11204,17193,'N-terminal peptidyl-glycine acetylation','P','The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.','2013-10-27','NSRP'),(11205,17194,'N-terminal peptidyl-isoleucine acetylation','P','The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.','2013-10-27','NSRP'),(11206,17195,'N-terminal peptidyl-lysine N2-acetylation','P','The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.','2013-10-27','NSRP'),(11207,17196,'N-terminal peptidyl-methionine acetylation','P','The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.','2013-10-27','NSRP'),(11208,17197,'N-terminal peptidyl-proline acetylation','P','The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.','2013-10-27','NSRP'),(11209,17198,'N-terminal peptidyl-serine acetylation','P','The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.','2013-10-27','NSRP'),(11210,17199,'N-terminal peptidyl-threonine acetylation','P','The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.','2013-10-27','NSRP'),(11211,18000,'N-terminal peptidyl-tyrosine acetylation','P','The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.','2013-10-27','NSRP'),(11212,18001,'N-terminal peptidyl-valine acetylation','P','The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.','2013-10-27','NSRP'),(11213,18002,'N-terminal peptidyl-glutamic acid acetylation','P','The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.','2013-10-27','NSRP'),(11214,18003,'peptidyl-lysine N6-acetylation','P','The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.','2013-10-27','NSRP'),(11215,18004,'N-terminal protein formylation','P','The formylation of the N-terminal amino acid of proteins.','2013-10-27','NSRP'),(11216,18005,'N-terminal peptidyl-glycine N-formylation','P','The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.','2013-10-27','NSRP'),(11217,18006,'N-terminal protein amino acid glucuronylation','P','The glucuronylation of the N-terminal amino acid of proteins.','2013-10-27','NSRP'),(11218,18007,'N-terminal peptidyl-glycine N-glucuronylation','P','The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.','2013-10-27','NSRP'),(11219,18008,'N-terminal peptidyl-glycine N-myristoylation','P','The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.','2013-10-27','NSRP'),(11220,18009,'N-terminal peptidyl-L-cysteine N-palmitoylation','P','The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.','2013-10-27','NSRP'),(11221,18010,'glycoprotein N-palmitoyltransferase activity','F','Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.','2013-10-27','NSRP'),(11222,18011,'N-terminal peptidyl-alanine methylation','P','The methylation of the N-terminal alanine of proteins.','2013-10-27','NSRP'),(11223,18012,'N-terminal peptidyl-alanine trimethylation','P','The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.','2013-10-27','NSRP'),(11224,18013,'N-terminal peptidyl-glycine methylation','P','The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.','2013-10-27','NSRP'),(11225,18014,'N-terminal peptidyl-methionine methylation','P','The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.','2013-10-27','NSRP'),(11226,18015,'N-terminal peptidyl-phenylalanine methylation','P','The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.','2013-10-27','NSRP'),(11227,18016,'N-terminal peptidyl-proline dimethylation','P','The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.','2013-10-27','NSRP'),(11228,18019,'N-terminal peptidyl-glutamine methylation','P','The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.','2013-10-27','NSRP'),(11229,18020,'peptidyl-glutamic acid methylation','P','The addition of a methyl group to a glutamic acid residue in a protein.','2013-10-27','NSRP'),(11230,18021,'peptidyl-histidine methylation','P','The methylation of peptidyl-L-histidine to form peptidyl-L-1\'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3\'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).','2013-10-27','NSRP'),(11231,18022,'peptidyl-lysine methylation','P','The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.','2013-10-27','NSRP'),(11232,18023,'peptidyl-lysine trimethylation','P','The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.','2013-10-27','NSRP'),(11233,18024,'histone-lysine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.','2013-10-27','NSRP'),(11234,18025,'calmodulin-lysine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.','2013-10-27','NSRP'),(11235,18026,'peptidyl-lysine monomethylation','P','The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.','2013-10-27','NSRP'),(11236,18027,'peptidyl-lysine dimethylation','P','The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.','2013-10-27','NSRP'),(11237,18028,'peptidyl-lysine myristoylation','P','The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.','2013-10-27','NSRP'),(11238,18029,'peptidyl-lysine palmitoylation','P','The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.','2013-10-27','NSRP'),(11239,18030,'peptidyl-lysine N6-myristoyltransferase activity','F','Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.','2013-10-27','NSRP'),(11240,18031,'peptidyl-lysine N6-palmitoyltransferase activity','F','Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.','2013-10-27','NSRP'),(11241,18032,'protein amidation','P','Addition of an amide group from a glycine to a protein amino acid.','2013-10-27','NSRP'),(11242,18033,'protein C-terminal amidation','P','The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.','2013-10-27','NSRP'),(11243,18034,'C-terminal peptidyl-alanine amidation','P','The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11244,18035,'C-terminal peptidyl-arginine amidation','P','The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11245,18036,'C-terminal peptidyl-asparagine amidation','P','The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11246,18037,'C-terminal peptidyl-aspartic acid amidation','P','The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11247,18038,'C-terminal peptidyl-cysteine amidation','P','The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11248,18039,'C-terminal peptidyl-glutamine amidation','P','The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11249,18040,'C-terminal peptidyl-glutamic acid amidation','P','The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11250,18041,'C-terminal peptidyl-glycine amidation','P','The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11251,18042,'C-terminal peptidyl-histidine amidation','P','The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11252,18043,'C-terminal peptidyl-isoleucine amidation','P','The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11253,18044,'C-terminal peptidyl-leucine amidation','P','The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11254,18045,'C-terminal peptidyl-lysine amidation','P','The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11255,18046,'C-terminal peptidyl-methionine amidation','P','The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11256,18047,'C-terminal peptidyl-phenylalanine amidation','P','The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11257,18048,'C-terminal peptidyl-proline amidation','P','The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11258,18049,'C-terminal peptidyl-serine amidation','P','The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11259,18050,'C-terminal peptidyl-threonine amidation','P','The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11260,18051,'C-terminal peptidyl-tryptophan amidation','P','The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11261,18052,'C-terminal peptidyl-tyrosine amidation','P','The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11262,18053,'C-terminal peptidyl-valine amidation','P','The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.','2013-10-27','NSRP'),(11263,18054,'peptidyl-lysine biotinylation','P','The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.','2013-10-27','NSRP'),(11264,18055,'peptidyl-lysine lipoylation','P','The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.','2013-10-27','NSRP'),(11265,18057,'peptidyl-lysine oxidation','P','The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.','2013-10-27','NSRP'),(11266,18058,'N-terminal protein amino acid deamination, from amino carbon','P','The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.','2013-10-27','NSRP'),(11267,18059,'N-terminal peptidyl-serine deamination','P','The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.','2013-10-27','NSRP'),(11268,18060,'N-terminal peptidyl-cysteine deamination','P','The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.','2013-10-27','NSRP'),(11269,18061,'peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine','P','The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.','2013-10-27','NSRP'),(11270,18062,'peptidyl-tryptophan succinylation','P','The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.','2013-10-27','NSRP'),(11271,18063,'cytochrome c-heme linkage','P','The linkage of cytochromes and other heme proteins to heme.','2013-10-27','NSRP'),(11272,18064,'protein-histidine N-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine.','2013-10-27','NSRP'),(11273,18065,'protein-cofactor linkage','P','The covalent attachment of a cofactor to a protein.','2013-10-27','NSRP'),(11274,18067,'peptidyl-L-3\',4\'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine','P','The modification of protein tyrosine to peptidyl-L-3\',4\'-dihydroxyphenylalanine (DOPA).','2013-10-27','NSRP'),(11275,18068,'peptidyl-L-2\',4\',5\'-topaquinone biosynthetic process from peptidyl-tyrosine','P','The modification of protein tyrosine to L-2\',4\',5\'-topaquinone, characteristic of the active site of copper amine oxidases.','2013-10-27','NSRP'),(11276,18069,'peptide cross-linking via 4\'-(L-tryptophan)-L-tryptophyl quinone','P','The cross-linking of a tryptophan residue to tryptophyl quinone to form 4\'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.','2013-10-27','NSRP'),(11277,18070,'peptidyl-serine phosphopantetheinylation','P','The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.','2013-10-27','NSRP'),(11278,18071,'NAD(P)-cysteine ADP-ribosyltransferase activity','F','Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine.','2013-10-27','NSRP'),(11279,18072,'peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid','P','The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.','2013-10-27','NSRP'),(11280,18073,'protein bromination','P','The addition of one or more bromine atoms to an amino acid residue in a protein.','2013-10-27','NSRP'),(11281,18074,'peptidyl-histidine bromination','P','The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown.','2013-10-27','NSRP'),(11282,18075,'peptidyl-phenylalanine bromination','P','The bromination of phenylalanine.','2013-10-27','NSRP'),(11283,18076,'N-terminal peptidyl-lysine acetylation','P','The acetylation of the N-terminal lysine of proteins.','2013-10-27','NSRP'),(11284,18077,'protein iodination','P','The addition of one or more iodine atoms to an amino acid residue in a protein.','2013-10-27','NSRP'),(11285,18078,'peptidyl-thyronine iodination','P','The iodination of peptidyl-thyronine, formed from tyrosine.','2013-10-27','NSRP'),(11286,18079,'protein halogenation','P','The addition of a halogen to a protein amino acid.','2013-10-27','NSRP'),(11287,18080,'peptidyl-tryptophan bromination','P','The bromination of peptidyl-tryptophan, to form peptidyl-L-6\'-bromotryptophan.','2013-10-27','NSRP'),(11288,18081,'peptide cross-linking via lanthionine or 3-methyl-lanthionine','P','The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.','2013-10-27','NSRP'),(11289,18082,'peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine','P','The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.','2013-10-27','NSRP'),(11290,18083,'peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine','P','The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.','2013-10-27','NSRP'),(11291,18084,'peptidyl-lactic acid biosynthetic process from peptidyl-serine','P','The modification of N-terminal peptidyl-serine to lactic acid.','2013-10-27','NSRP'),(11292,18085,'peptidyl-L-amino acid racemization','P','The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.','2013-10-27','NSRP'),(11293,18086,'alanine racemization','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11294,18091,'peptidyl-asparagine racemization','P','The racemization of peptidyl-asparagine.','2013-10-27','NSRP'),(11295,18094,'protein polyglycylation','P','The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.','2013-10-27','NSRP'),(11296,18095,'protein polyglutamylation','P','The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.','2013-10-27','NSRP'),(11297,18096,'peptide cross-linking via S-(2-aminovinyl)-D-cysteine','P','The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine.','2013-10-27','NSRP'),(11298,18097,'protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine','P','The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine.','2013-10-27','NSRP'),(11299,18101,'protein citrullination','P','The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.','2013-10-27','NSRP'),(11300,18102,'peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine','P','The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.','2013-10-27','NSRP'),(11301,18103,'protein C-linked glycosylation','P','A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.','2013-10-27','NSRP'),(11302,18104,'peptidoglycan-protein cross-linking','P','The process of covalently linking peptidoglycan (murein) to proteins.','2013-10-27','NSRP'),(11303,18105,'peptidyl-serine phosphorylation','P','The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.','2013-10-27','NSRP'),(11304,18106,'peptidyl-histidine phosphorylation','P','The phosphorylation of peptidyl-histidine to form peptidyl-1\'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3\'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).','2013-10-27','NSRP'),(11305,18107,'peptidyl-threonine phosphorylation','P','The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.','2013-10-27','NSRP'),(11306,18108,'peptidyl-tyrosine phosphorylation','P','The phosphorylation of peptidyl-tyrosine to form peptidyl-O4\'-phospho-L-tyrosine.','2013-10-27','NSRP'),(11307,18109,'peptidyl-arginine phosphorylation','P','The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.','2013-10-27','NSRP'),(11308,18110,'histone arginine kinase activity','F','Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+).','2013-10-27','NSRP'),(11309,18111,'methionine racemase activity','F','Catalysis of the reaction: L-methionine = D-methionine.','2013-10-27','NSRP'),(11310,18112,'proline racemase activity','F','Catalysis of the reaction: L-proline = D-proline.','2013-10-27','NSRP'),(11311,18113,'lysine racemase activity','F','Catalysis of the reaction: L-lysine = D-lysine.','2013-10-27','NSRP'),(11312,18114,'threonine racemase activity','F','Catalysis of the reaction: L-threonine = D-threonine.','2013-10-27','NSRP'),(11313,18115,'peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine','P','The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.','2013-10-27','NSRP'),(11314,18116,'peptidyl-lysine adenylylation','P','The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5\'-adenosine)-L-lysine.','2013-10-27','NSRP'),(11315,18117,'protein adenylylation','P','The addition of an adenylyl group (adenosine 5\'-monophosphate; AMP) to a protein amino acid.','2013-10-27','NSRP'),(11316,18118,'peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide.','2013-10-27','NSRP'),(11317,18119,'peptidyl-cysteine S-nitrosylation','P','The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.','2013-10-27','NSRP'),(11318,18120,'peptidyl-arginine ADP-ribosylation','P','The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.','2013-10-27','NSRP'),(11319,18121,'NAD(P)-asparagine ADP-ribosyltransferase activity','F','Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine.','2013-10-27','NSRP'),(11320,18122,'peptidyl-asparagine ADP-ribosylation','P','The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine.','2013-10-27','NSRP'),(11321,18123,'peptidyl-cysteine ADP-ribosylation','P','The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine.','2013-10-27','NSRP'),(11322,18124,'peptide cross-linking via 5\'-(N6-L-lysine)-L-topaquinone','P','The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.','2013-10-27','NSRP'),(11323,18125,'peptidyl-cysteine methylation','P','The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.','2013-10-27','NSRP'),(11324,18126,'protein hydroxylation','P','The addition of a hydroxy group to a protein amino acid.','2013-10-27','NSRP'),(11325,18127,'NAD(P)-serine ADP-ribosyltransferase activity','F','Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine.','2013-10-27','NSRP'),(11326,18128,'peptidyl-serine cyclase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11327,18129,'peptidyl-oxazoline dehydrogenase activity','F','Catalysis of the reduction of a peptide-linked oxazoline to oxazole.','2013-10-27','NSRP'),(11328,18130,'heterocycle biosynthetic process','P','The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).','2013-10-27','NSRP'),(11329,18131,'oxazole or thiazole biosynthetic process','P','The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.','2013-10-27','NSRP'),(11330,18132,'peptide cross-linking via L-cysteine oxazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11331,18133,'peptide cross-linking via L-cysteine oxazolinecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.','2013-10-27','NSRP'),(11332,18134,'peptide cross-linking via glycine oxazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11333,18135,'peptidyl-cysteine cyclase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11334,18136,'peptidyl-thiazoline dehydrogenase activity','F','Catalysis of the reduction of a peptide-linked thiazoline to thiazole.','2013-10-27','NSRP'),(11335,18137,'peptide cross-linking via glycine thiazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11336,18138,'peptide cross-linking via L-serine thiazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11337,18139,'peptide cross-linking via L-phenylalanine thiazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11338,18140,'peptide cross-linking via L-cysteine thiazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11339,18141,'peptide cross-linking via L-lysine thiazolecarboxylic acid','P','The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11340,18142,'protein-DNA covalent cross-linking','P','The formation of a covalent cross-link between DNA and a protein.','2013-10-27','NSRP'),(11341,18143,'nucleic acid-protein covalent cross-linking','P','The formation of a covalent cross-link between a nucleic acid and a protein.','2013-10-27','NSRP'),(11342,18144,'RNA-protein covalent cross-linking','P','The formation of a covalent cross-link between RNA and a protein.','2013-10-27','NSRP'),(11343,18145,'protein-DNA covalent cross-linking via peptidyl-serine','P','The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5\'-DNA)-L-serine.','2013-10-27','NSRP'),(11344,18146,'keratan sulfate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.','2013-10-27','NSRP'),(11345,18147,'molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)','P','The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).','2013-10-27','NSRP'),(11346,18148,'RNA-protein covalent cross-linking via peptidyl-tyrosine','P','The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4\'-(phospho-5\'-RNA)-L-tyrosine.','2013-10-27','NSRP'),(11347,18149,'peptide cross-linking','P','The formation of a covalent cross-link between or within protein chains.','2013-10-27','NSRP'),(11348,18150,'peptide cross-linking via 3-(3\'-L-histidyl)-L-tyrosine','P','The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3\'-L-histidyl)-L-tyrosine protein cross-link.','2013-10-27','NSRP'),(11349,18151,'peptide cross-linking via L-histidyl-L-tyrosine','P','The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link.','2013-10-27','NSRP'),(11350,18152,'peptide cross-linking via 3\'-(1\'-L-histidyl)-L-tyrosine','P','The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3\'-(1\'-L-histidyl)-L-tyrosine protein cross-link.','2013-10-27','NSRP'),(11351,18153,'isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine','P','The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.','2013-10-27','NSRP'),(11352,18154,'peptide cross-linking via (2R,6R)-lanthionine','P','The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).','2013-10-27','NSRP'),(11353,18155,'peptide cross-linking via sn-(2S,6R)-lanthionine','P','The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).','2013-10-27','NSRP'),(11354,18156,'peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine','P','The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).','2013-10-27','NSRP'),(11355,18157,'peptide cross-linking via an oxazole or thiazole','P','The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.','2013-10-27','NSRP'),(11356,18158,'protein oxidation','P','The modification of a protein amino acid by oxidation.','2013-10-27','NSRP'),(11357,18159,'peptidyl-methionine oxidation','P','The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.','2013-10-27','NSRP'),(11358,18160,'peptidyl-pyrromethane cofactor linkage','P','The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.','2013-10-27','NSRP'),(11359,18161,'dipyrrin biosynthetic process','P','The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.','2013-10-27','NSRP'),(11360,18162,'peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine','P','The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.','2013-10-27','NSRP'),(11361,18163,'protein-DNA covalent cross-linking via the 5\'-end to peptidyl-tyrosine','P','The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4\'-(phospho-5\'-DNA)-L-tyrosine.','2013-10-27','NSRP'),(11362,18164,'protein-DNA covalent cross-linking via peptidyl-threonine','P','The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5\'-DNA)-L-threonine.','2013-10-27','NSRP'),(11363,18165,'peptidyl-tyrosine uridylylation','P','The uridylylation of peptidyl-tyrosine to form peptidyl-O4\'-(phospho-5\'-uridine)-L-tyrosine, found in glutamine synthetase.','2013-10-27','NSRP'),(11364,18166,'C-terminal protein-tyrosinylation','P','The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.','2013-10-27','NSRP'),(11365,18167,'protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine','P','The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.','2013-10-27','NSRP'),(11366,18168,'protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine','P','The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.','2013-10-27','NSRP'),(11367,18169,'ribosomal S6-glutamic acid ligase activity','F','Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.','2013-10-27','NSRP'),(11368,18170,'C-terminal peptidyl-polyglutamic acid amidation','P','The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.','2013-10-27','NSRP'),(11369,18171,'peptidyl-cysteine oxidation','P','The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.','2013-10-27','NSRP'),(11370,18172,'peptidyl-L-3\',4\',5\'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine','P','The modification of protein tyrosine to peptidyl-L-3\',4\',5\'-dihydroxyphenylalanine.','2013-10-27','NSRP'),(11371,18173,'peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine','P','The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.','2013-10-27','NSRP'),(11372,18174,'protein-heme P460 linkage','P','The linkage of protein to heme P460.','2013-10-27','NSRP'),(11373,18175,'protein nucleotidylation','P','The addition of a nucleotide to a protein amino acid.','2013-10-27','NSRP'),(11374,18177,'protein uridylylation','P','The addition of phospho-uridine to a protein amino acid.','2013-10-27','NSRP'),(11375,18178,'peptidyl-threonine adenylylation','P','The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5\'-adenosine)-L-threonine.','2013-10-27','NSRP'),(11376,18179,'peptidyl-cysteine desulfurization','P','OBSOLETE. The desulfurization of peptidyl-L-cysteine to yield L-alanine and elemental sulfur; peptidyl-L-cysteine persulfide is an intermediate.','2013-10-27','NSRP'),(11377,18180,'protein desulfurization','P','The removal of a sulfur group from a protein amino acid.','2013-10-27','NSRP'),(11378,18181,'peptidyl-arginine C5-methylation','P','The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine.','2013-10-27','NSRP'),(11379,18182,'protein-heme linkage via 3\'-L-histidine','P','The covalent linkage of heme and a protein via 3\'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).','2013-10-27','NSRP'),(11380,18183,'enzyme active site formation via S-selenyl-L-cysteine','P','OBSOLETE. The transient selenylation of peptidyl-cysteine to form S-selenyl-L-cysteine.','2013-10-27','NSRP'),(11381,18184,'protein polyamination','P','The modification of a protein amino acid by polyamination.','2013-10-27','NSRP'),(11382,18185,'poly-N-methyl-propylamination','P','The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.','2013-10-27','NSRP'),(11383,18186,'peroxidase-heme linkage','P','The covalent linkage of heme to peroxidase.','2013-10-27','NSRP'),(11384,18187,'molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide','P','The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.','2013-10-27','NSRP'),(11385,18188,'peptidyl-proline di-hydroxylation','P','The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.','2013-10-27','NSRP'),(11386,18189,'pyrroloquinoline quinone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.','2013-10-27','NSRP'),(11387,18190,'protein octanoylation','P','The modification of a protein amino acid by formation of an ester or amide with octanoic acid.','2013-10-27','NSRP'),(11388,18191,'peptidyl-serine octanoylation','P','The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.','2013-10-27','NSRP'),(11389,18192,'enzyme active site formation via L-cysteine persulfide','P','The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide. A persulfurated cysteine promotes active site reactivity in Azotobacter vinelandii Rhodanese.','2013-10-27','NSRP'),(11390,18193,'peptidyl-amino acid modification','P','The alteration of an amino acid residue in a peptide.','2013-10-27','NSRP'),(11391,18194,'peptidyl-alanine modification','P','The modification of peptidyl-alanine.','2013-10-27','NSRP'),(11392,18195,'peptidyl-arginine modification','P','The modification of peptidyl-arginine.','2013-10-27','NSRP'),(11393,18196,'peptidyl-asparagine modification','P','The modification of peptidyl-asparagine.','2013-10-27','NSRP'),(11394,18197,'peptidyl-aspartic acid modification','P','The modification of peptidyl-aspartic acid.','2013-10-27','NSRP'),(11395,18198,'peptidyl-cysteine modification','P','The modification of peptidyl-cysteine.','2013-10-27','NSRP'),(11396,18199,'peptidyl-glutamine modification','P','The modification of peptidyl-glutamine.','2013-10-27','NSRP'),(11397,18200,'peptidyl-glutamic acid modification','P','The modification of peptidyl-glutamic acid.','2013-10-27','NSRP'),(11398,18201,'peptidyl-glycine modification','P','The modification of peptidyl-glycine.','2013-10-27','NSRP'),(11399,18202,'peptidyl-histidine modification','P','The modification of peptidyl-histidine.','2013-10-27','NSRP'),(11400,18203,'peptidyl-isoleucine modification','P','The modification of peptidyl-isoleucine.','2013-10-27','NSRP'),(11401,18204,'peptidyl-leucine modification','P','The modification of peptidyl-leucine.','2013-10-27','NSRP'),(11402,18205,'peptidyl-lysine modification','P','The modification of peptidyl-lysine.','2013-10-27','NSRP'),(11403,18206,'peptidyl-methionine modification','P','The modification of peptidyl-methionine.','2013-10-27','NSRP'),(11404,18207,'peptidyl-phenylalanine modification','P','The modification of peptidyl-phenylalanine.','2013-10-27','NSRP'),(11405,18208,'peptidyl-proline modification','P','The modification of peptidyl-proline.','2013-10-27','NSRP'),(11406,18209,'peptidyl-serine modification','P','The modification of peptidyl-serine.','2013-10-27','NSRP'),(11407,18210,'peptidyl-threonine modification','P','The modification of peptidyl-threonine.','2013-10-27','NSRP'),(11408,18211,'peptidyl-tryptophan modification','P','The chemical alteration of a tryptophan residue in a peptide.','2013-10-27','NSRP'),(11409,18212,'peptidyl-tyrosine modification','P','The modification of peptidyl-tyrosine.','2013-10-27','NSRP'),(11410,18213,'peptidyl-valine modification','P','The modification of peptidyl-valine.','2013-10-27','NSRP'),(11411,18214,'protein carboxylation','P','The addition of a carboxy group to a protein amino acid.','2013-10-27','NSRP'),(11412,18215,'protein phosphopantetheinylation','P','The modification of a protein amino acid by phosphopantetheinylation.','2013-10-27','NSRP'),(11413,18216,'peptidyl-arginine methylation','P','The addition of a methyl group to an arginine residue in a protein.','2013-10-27','NSRP'),(11414,18217,'peptidyl-aspartic acid phosphorylation','P','The phosphorylation of peptidyl-aspartic acid.','2013-10-27','NSRP'),(11415,18218,'peptidyl-cysteine phosphorylation','P','The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.','2013-10-27','NSRP'),(11416,18219,'peptidyl-cysteine S-acetylation','P','The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.','2013-10-27','NSRP'),(11417,18220,'peptidyl-threonine palmitoylation','P','The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.','2013-10-27','NSRP'),(11418,18221,'peptidyl-serine palmitoylation','P','The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.','2013-10-27','NSRP'),(11419,18222,'peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide.','2013-10-27','NSRP'),(11420,18226,'peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.','2013-10-27','NSRP'),(11421,18227,'peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.','2013-10-27','NSRP'),(11422,18228,'peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.','2013-10-27','NSRP'),(11423,18229,'peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine','P','The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester.','2013-10-27','NSRP'),(11424,18230,'peptidyl-L-cysteine S-palmitoylation','P','The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.','2013-10-27','NSRP'),(11425,18231,'peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine','P','The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3\') and unsaturated (generally at 2\') fatty acids.','2013-10-27','NSRP'),(11426,18232,'peptide cross-linking via S-(L-isoglutamyl)-L-cysteine','P','The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.','2013-10-27','NSRP'),(11427,18233,'peptide cross-linking via 2\'-(S-L-cysteinyl)-L-histidine','P','The modification of peptidyl-histidine and peptidyl-cysteine to form a 2\'-(S-L-cysteinyl)-L-histidine protein cross-link.','2013-10-27','NSRP'),(11428,18234,'peptide cross-linking via 3\'-(S-L-cysteinyl)-L-tyrosine','P','The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3\'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.','2013-10-27','NSRP'),(11429,18235,'peptidyl-lysine carboxylation','P','The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.','2013-10-27','NSRP'),(11430,18237,'urease activator activity','F','Increases the activity of urease by promoting the incorporation of nickel into the active site.','2013-10-27','NSRP'),(11431,18238,'peptidyl-lysine carboxyethylation','P','The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.','2013-10-27','NSRP'),(11432,18240,'protein S-linked glycosylation via cysteine','P','The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.','2013-10-27','NSRP'),(11433,18241,'protein O-linked glycosylation via hydroxylysine','P','The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.','2013-10-27','NSRP'),(11434,18242,'protein O-linked glycosylation via serine','P','The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.','2013-10-27','NSRP'),(11435,18243,'protein O-linked glycosylation via threonine','P','The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.','2013-10-27','NSRP'),(11436,18244,'protein N-linked glycosylation via tryptophan','P','The glycosylation of protein via peptidyl-tryptophan, 1\'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.','2013-10-27','NSRP'),(11437,18245,'protein O-linked glycosylation via tyrosine','P','The glycosylation of protein via the O4\' atom of peptidyl-tyrosine, O4\'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.','2013-10-27','NSRP'),(11438,18246,'protein-coenzyme A linkage','P','The formation of a linkage between a protein amino acid and coenzyme A.','2013-10-27','NSRP'),(11439,18247,'protein-phosphoribosyl dephospho-coenzyme A linkage','P','The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2\' or the 3\' position.','2013-10-27','NSRP'),(11440,18248,'enzyme active site formation via S-sulfo-L-cysteine','P','The transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.','2013-10-27','NSRP'),(11441,18249,'protein dehydration','P','The removal of a water group from a protein amino acid.','2013-10-27','NSRP'),(11442,18250,'peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine','P','The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.','2013-10-27','NSRP'),(11443,18251,'peptidyl-tyrosine dehydrogenation','P','The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.','2013-10-27','NSRP'),(11444,18252,'peptide cross-linking via L-seryl-5-imidazolinone glycine','P','The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.','2013-10-27','NSRP'),(11445,18253,'peptide cross-linking via 5-imidazolinone glycine','P','The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.','2013-10-27','NSRP'),(11446,18254,'peptidyl-tyrosine adenylylation','P','The adenylylation of peptidyl-tyrosine to form peptidyl-O4\'-(phospho-5\'-adenosine)-L-tyrosine.','2013-10-27','NSRP'),(11447,18255,'peptide cross-linking via S-glycyl-L-cysteine','P','The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins.','2013-10-27','NSRP'),(11448,18256,'protein formylation','P','The addition of a formyl group to a protein amino acid.','2013-10-27','NSRP'),(11449,18257,'peptidyl-lysine formylation','P','The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.','2013-10-27','NSRP'),(11450,18258,'protein O-linked glycosylation via hydroxyproline','P','The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.','2013-10-27','NSRP'),(11451,18259,'RNA-protein covalent cross-linking via peptidyl-serine','P','The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5\'-5NA)-L-serine.','2013-10-27','NSRP'),(11452,18260,'protein guanylylation','P','The addition of phospho-guanosine to a protein amino acid.','2013-10-27','NSRP'),(11453,18261,'peptidyl-lysine guanylylation','P','The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5\'-guanosine)-L-lysine.','2013-10-27','NSRP'),(11454,18262,'isopeptide cross-linking','P','The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.','2013-10-27','NSRP'),(11455,18263,'isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine','P','The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.','2013-10-27','NSRP'),(11456,18264,'isopeptide cross-linking via N-(L-isoaspartyl)-glycine','P','The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine.','2013-10-27','NSRP'),(11457,18265,'GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11458,18266,'GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11459,18267,'GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11460,18268,'GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11461,18269,'GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11462,18270,'GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine','P','The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11463,18271,'biotin-protein ligase activity','F','Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.','2013-10-27','NSRP'),(11464,18272,'protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine','P','The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.','2013-10-27','NSRP'),(11465,18273,'protein-chromophore linkage via peptidyl-N6-retinal-L-lysine','P','The modification of peptidyl-lysine to form N6-retinal-L-lysine.','2013-10-27','NSRP'),(11466,18274,'peptide cross-linking via L-lysinoalanine','P','The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.','2013-10-27','NSRP'),(11467,18275,'N-terminal peptidyl-cysteine acetylation','P','The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.','2013-10-27','NSRP'),(11468,18276,'isopeptide cross-linking via N6-glycyl-L-lysine','P','The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.','2013-10-27','NSRP'),(11469,18277,'protein deamination','P','The removal of an amino group from a protein amino acid.','2013-10-27','NSRP'),(11470,18278,'N-terminal peptidyl-threonine deamination','P','The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.','2013-10-27','NSRP'),(11471,18279,'protein N-linked glycosylation via asparagine','P','The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.','2013-10-27','NSRP'),(11472,18280,'protein S-linked glycosylation','P','A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.','2013-10-27','NSRP'),(11473,18281,'GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine','P','The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.','2013-10-27','NSRP'),(11474,18282,'metal incorporation into metallo-sulfur cluster','P','The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.','2013-10-27','NSRP'),(11475,18283,'iron incorporation into metallo-sulfur cluster','P','The incorporation of iron into a metallo-sulfur cluster.','2013-10-27','NSRP'),(11476,18284,'iron incorporation into protein via tetrakis-L-cysteinyl iron','P','The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).','2013-10-27','NSRP'),(11477,18285,'iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide','P','The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.','2013-10-27','NSRP'),(11478,18286,'iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide','P','OBSOLETE. The incorporation of iron into a 3Fe-3S iron-sulfur cluster via hexakis-L-cysteinyl triiron trisulfide. The three-iron three-sulfur cluster probably does not exist except as an intermediate form.','2013-10-27','NSRP'),(11479,18287,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide','P','The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.','2013-10-27','NSRP'),(11480,18288,'iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.','2013-10-27','NSRP'),(11481,18289,'molybdenum incorporation into metallo-sulfur cluster','P','The incorporation of molybdenum into a metallo-sulfur cluster.','2013-10-27','NSRP'),(11482,18290,'iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide','P','The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.','2013-10-27','NSRP'),(11483,18291,'molybdenum incorporation into iron-sulfur cluster','P','The incorporation of molybdenum into an iron-sulfur cluster.','2013-10-27','NSRP'),(11484,18292,'molybdenum incorporation via L-cysteinyl molybdopterin','P','The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.','2013-10-27','NSRP'),(11485,18293,'protein-FAD linkage','P','The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).','2013-10-27','NSRP'),(11486,18294,'protein-FAD linkage via S-(8alpha-FAD)-L-cysteine','P','The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine.','2013-10-27','NSRP'),(11487,18295,'protein-FAD linkage via 3\'-(8alpha-FAD)-L-histidine','P','The formation of a protein-FAD linkage via 3\'-(8-alpha-FAD)-L-histidine.','2013-10-27','NSRP'),(11488,18296,'protein-FAD linkage via O4\'-(8alpha-FAD)-L-tyrosine','P','The formation of a protein-FAD linkage via O4\'-(8-alpha-FAD)-L-tyrosine.','2013-10-27','NSRP'),(11489,18297,'protein-FAD linkage via 1\'-(8alpha-FAD)-L-histidine','P','The formation of a protein-FAD linkage via 1\'-(8-alpha-FAD)-L-histidine.','2013-10-27','NSRP'),(11490,18298,'protein-chromophore linkage','P','The covalent or noncovalent attachment of a chromophore to a protein.','2013-10-27','NSRP'),(11491,18299,'iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide','P','The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.','2013-10-27','NSRP'),(11492,18300,'iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl hexairon hexasulfide','P','OBSOLETE. The incorporation of iron into a 6Fe-6S cluster by hexakis-L-cysteinyl hexairon hexasulfide.','2013-10-27','NSRP'),(11493,18301,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon','P','The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.','2013-10-27','NSRP'),(11494,18302,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1\'-histidino tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1\'-histidino tetrairon tetrasulfide.','2013-10-27','NSRP'),(11495,18303,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3\'-histidino tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3\'-histidino tetrairon tetrasulfide.','2013-10-27','NSRP'),(11496,18304,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.','2013-10-27','NSRP'),(11497,18305,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.','2013-10-27','NSRP'),(11498,18306,'iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3\'-histidino-L-serinyl tetrairon tetrasulfide','P','The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3\'-histidino-L-serinyl tetrairon tetrasulfide.','2013-10-27','NSRP'),(11499,18307,'enzyme active site formation','P','The modification of part of an enzyme to form the active site.','2013-10-27','NSRP'),(11500,18308,'enzyme active site formation via N6-pyruvic acid 2-iminyl-L-lysine','P','OBSOLETE. The transient modification of lysine by pyruvate to form N6-pyruvic acid 2-iminyl-L-lysine, found in the active site of dihydrodipicolinate synthase.','2013-10-27','NSRP'),(11501,18309,'protein-FMN linkage','P','The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN).','2013-10-27','NSRP'),(11502,18310,'protein-FMN linkage via S-(6-FMN)-L-cysteine','P','The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine.','2013-10-27','NSRP'),(11503,18311,'peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine','P','The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine.','2013-10-27','NSRP'),(11504,18312,'peptidyl-serine ADP-ribosylation','P','The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine.','2013-10-27','NSRP'),(11505,18313,'peptide cross-linking via L-alanyl-5-imidazolinone glycine','P','The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.','2013-10-27','NSRP'),(11506,18314,'protein-pyrroloquinoline-quinone linkage','P','OBSOLETE. The covalent cross-linking of pyrroloquinoline-quinone to peptidyl-glutamic acid and peptidyl-tyrosine.','2013-10-27','NSRP'),(11507,18315,'molybdenum incorporation into molybdenum-molybdopterin complex','P','The incorporation of molybdenum into a molybdenum-molybdopterin complex.','2013-10-27','NSRP'),(11508,18316,'peptide cross-linking via L-cystine','P','The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.','2013-10-27','NSRP'),(11509,18317,'protein C-linked glycosylation via tryptophan','P','The glycosylation of a carbon atom of a peptidyl-tryptophan residue.','2013-10-27','NSRP'),(11510,18320,'enzyme active site formation via S-methyl-L-cysteine','P','The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine.','2013-10-27','NSRP'),(11511,18321,'protein glucuronylation','P','The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.','2013-10-27','NSRP'),(11512,18322,'protein tyrosinylation','P','The addition of a tyrosine molecule to a protein amino acid.','2013-10-27','NSRP'),(11513,18323,'enzyme active site formation via L-cysteine sulfinic acid','P','The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid.','2013-10-27','NSRP'),(11514,18324,'enzyme active site formation via L-cysteine sulfenic acid','P','The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.','2013-10-27','NSRP'),(11515,18325,'enzyme active site formation via S-phospho-L-cysteine','P','The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine.','2013-10-27','NSRP'),(11516,18326,'enzyme active site formation via S-acetyl-L-cysteine','P','The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine.','2013-10-27','NSRP'),(11517,18327,'enzyme active site formation via 1\'-phospho-L-histidine','P','The transient phosphorylation of peptidyl-histidine to form 1\'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).','2013-10-27','NSRP'),(11518,18328,'enzyme active site formation via 3\'-phospho-L-histidine','P','The transient phosphorylation of peptidyl-histidine to form 3\'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).','2013-10-27','NSRP'),(11519,18329,'enzyme active site formation via N6-(phospho-5\'-adenosine)-L-lysine','P','The transient adenylylation of lysine to form N6-(phospho-5\'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.','2013-10-27','NSRP'),(11520,18330,'enzyme active site formation via N6-(phospho-5\'-guanosine)-L-lysine','P','The transient guanylylation of lysine to form N6-(phospho-5\'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.','2013-10-27','NSRP'),(11521,18331,'enzyme active site formation via O-phospho-L-serine','P','The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine.','2013-10-27','NSRP'),(11522,18332,'enzyme active site formation via O-(phospho-5\'-adenosine)-L-threonine','P','The transient adenylylation of threonine to form N6-(phospho-5\'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.','2013-10-27','NSRP'),(11523,18333,'enzyme active site formation via O-phospho-L-threonine','P','The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine.','2013-10-27','NSRP'),(11524,18334,'enzyme active site formation via O4\'-phospho-L-tyrosine','P','The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine.','2013-10-27','NSRP'),(11525,18335,'protein succinylation','P','The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.','2013-10-27','NSRP'),(11526,18336,'peptidyl-tyrosine hydroxylation','P','The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.','2013-10-27','NSRP'),(11527,18337,'enzyme active site formation via L-2\',4\',5\'-topaquinone','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11528,18338,'protein amino acid cinnamylation','P','OBSOLETE. The modification of a protein amino acid by cinnamylation.','2013-10-27','NSRP'),(11529,18339,'peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid','P','The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.','2013-10-27','NSRP'),(11530,18340,'peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine','P','The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine.','2013-10-27','NSRP'),(11531,18341,'peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine','P','The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine.','2013-10-27','NSRP'),(11532,18342,'protein prenylation','P','The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.','2013-10-27','NSRP'),(11533,18343,'protein farnesylation','P','The covalent attachment of a farnesyl group to a protein.','2013-10-27','NSRP'),(11534,18344,'protein geranylgeranylation','P','The covalent attachment of a geranylgeranyl group to a protein.','2013-10-27','NSRP'),(11535,18345,'protein palmitoylation','P','The covalent attachment of a palmitoyl group to a protein.','2013-10-27','NSRP'),(11536,18350,'protein esterification','P','The addition of an ester group to a protein amino acid.','2013-10-27','NSRP'),(11537,18351,'peptidyl-cysteine esterification','P','The addition of an ester group to a cysteine residue in a protein.','2013-10-27','NSRP'),(11538,18352,'protein-pyridoxal-5-phosphate linkage','P','The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.','2013-10-27','NSRP'),(11539,18353,'protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine','P','The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.','2013-10-27','NSRP'),(11540,18355,'protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine','P','The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.','2013-10-27','NSRP'),(11541,18356,'protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine','P','The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.','2013-10-27','NSRP'),(11542,18357,'protein-phycourobilin linkage via phycourobilin-bis-L-cysteine','P','The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.','2013-10-27','NSRP'),(11543,18358,'protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine','P','The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.','2013-10-27','NSRP'),(11544,18359,'protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine','P','The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.','2013-10-27','NSRP'),(11545,18360,'protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine','P','The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine.','2013-10-27','NSRP'),(11546,18361,'peptidyl-glutamine 2-methylation','P','The methylation of glutamine to form 2-methyl-L-glutamine.','2013-10-27','NSRP'),(11547,18362,'peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester','P','The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.','2013-10-27','NSRP'),(11548,18363,'peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium','P','The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.','2013-10-27','NSRP'),(11549,18364,'peptidyl-glutamine methylation','P','The addition of a methyl group to a glutamine residue in a protein.','2013-10-27','NSRP'),(11550,18365,'protein-serine epimerase activity','F','Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.','2013-10-27','NSRP'),(11551,18366,'chiral amino acid racemization','P','The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.','2013-10-27','NSRP'),(11552,18367,'free L-amino acid racemization','P','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11553,18376,'peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine','P','The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).','2013-10-27','NSRP'),(11554,18377,'protein myristoylation','P','The covalent attachment of a myristoyl group to a protein.','2013-10-27','NSRP'),(11555,18378,'cytochrome c-heme linkage via heme-L-cysteine','P','The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine.','2013-10-27','NSRP'),(11556,18379,'cytochrome c-heme linkage via heme-bis-L-cysteine','P','The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.','2013-10-27','NSRP'),(11557,18386,'N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine','P','The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.','2013-10-27','NSRP'),(11558,18387,'N-terminal peptidyl-amino acid deamination to pyruvic acid','P','The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.','2013-10-27','NSRP'),(11559,18388,'N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine','P','The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.','2013-10-27','NSRP'),(11560,18389,'N-terminal peptidyl-valine deamination','P','The deamination of the N-terminal valine residue of a protein to form isobutyrate.','2013-10-27','NSRP'),(11561,18390,'peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine','P','The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester.','2013-10-27','NSRP'),(11562,18391,'C-terminal peptidyl-glutamic acid tyrosinylation','P','The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.','2013-10-27','NSRP'),(11563,18392,'glycoprotein 3-alpha-L-fucosyltransferase activity','F','Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+).','2013-10-27','NSRP'),(11564,18393,'internal peptidyl-lysine acetylation','P','The addition of an acetyl group to a non-terminal lysine residue in a protein.','2013-10-27','NSRP'),(11565,18394,'peptidyl-lysine acetylation','P','The acetylation of peptidyl-lysine.','2013-10-27','NSRP'),(11566,18395,'peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine','P','The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.','2013-10-27','NSRP'),(11567,18396,'peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine','P','The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.','2013-10-27','NSRP'),(11568,18397,'peptidyl-phenylalanine bromination to L-2\'-bromophenylalanine','P','The bromination of peptidyl-phenylalanine to form L-2\'-bromophenylalanine.','2013-10-27','NSRP'),(11569,18398,'peptidyl-phenylalanine bromination to L-3\'-bromophenylalanine','P','The bromination of peptidyl-phenylalanine to form L-3\'-bromophenylalanine.','2013-10-27','NSRP'),(11570,18399,'peptidyl-phenylalanine bromination to L-4\'-bromophenylalanine','P','The bromination of peptidyl-phenylalanine to form L-4\'-bromophenylalanine.','2013-10-27','NSRP'),(11571,18400,'peptidyl-proline hydroxylation to 3-hydroxy-L-proline','P','The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.','2013-10-27','NSRP'),(11572,18401,'peptidyl-proline hydroxylation to 4-hydroxy-L-proline','P','The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.','2013-10-27','NSRP'),(11573,18402,'protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine','P','Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.','2013-10-27','NSRP'),(11574,18403,'protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine','P','Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.','2013-10-27','NSRP'),(11575,18404,'protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine','P','Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.','2013-10-27','NSRP'),(11576,18405,'protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine','P','Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.','2013-10-27','NSRP'),(11577,18406,'protein C-linked glycosylation via 2\'-alpha-mannosyl-L-tryptophan','P','The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.','2013-10-27','NSRP'),(11578,18407,'peptidyl-thyronine iodination to form 3\',3\'\',5\'-triiodo-L-thyronine','P','The iodination of peptidyl-thyronine to form peptidyl-3\',3\'\',5\'-triiodo-L-thyronine (triiodothyronine).','2013-10-27','NSRP'),(11579,18408,'peptidyl-thyronine iodination to form 3\',3\'\',5\',5\'\'-tetraiodo-L-thyronine','P','The iodination of peptidyl-thyronine to form peptidyl-3\',3\'\',5\',5\'\'-tetraiodo-L-thyronine (L-thyroxine).','2013-10-27','NSRP'),(11580,18410,'C-terminal protein amino acid modification','P','The alteration of the C-terminal amino acid residue in a protein.','2013-10-27','NSRP'),(11581,18411,'protein glucuronidation','P','The modification of a protein by amino acid glucuronidation.','2013-10-27','NSRP'),(11582,18412,'protein O-glucuronidation','P','The modification of a protein by glucuronidation on an amino acid oxygen atom.','2013-10-27','NSRP'),(11583,18413,'peptidyl-serine O-glucuronidation','P','The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.','2013-10-27','NSRP'),(11584,18414,'nickel incorporation into metallo-sulfur cluster','P','The incorporation of nickel into a metallo-sulfur cluster.','2013-10-27','NSRP'),(11585,18415,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide','P','The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.','2013-10-27','NSRP'),(11586,18416,'nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide','P','The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.','2013-10-27','NSRP'),(11587,18417,'iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide','P','The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.','2013-10-27','NSRP'),(11588,18418,'nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide','P','The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.','2013-10-27','NSRP'),(11589,18419,'protein catenane formation','P','The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.','2013-10-27','NSRP'),(11590,18420,'peptide cross-linking via N6-(L-isoaspartyl)-L-lysine','P','The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues.','2013-10-27','NSRP'),(11591,18421,'UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity','F','Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.','2013-10-27','NSRP'),(11592,18422,'GDP-mannose:serine-protein mannose-1-phosphotransferase activity','F','Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.','2013-10-27','NSRP'),(11593,18423,'protein C-terminal leucine carboxyl O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.','2013-10-27','NSRP'),(11594,18424,'peptidyl-glutamic acid poly-ADP-ribosylation','P','This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.','2013-10-27','NSRP'),(11595,18425,'O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.','2013-10-27','NSRP'),(11596,18426,'O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.','2013-10-27','NSRP'),(11597,18427,'copper incorporation into metallo-sulfur cluster','P','The incorporation of copper into a metallo-sulfur cluster.','2013-10-27','NSRP'),(11598,18428,'copper incorporation into copper-sulfur cluster','P','The incorporation of copper into a copper-sulfur cluster.','2013-10-27','NSRP'),(11599,18429,'copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide','P','The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.','2013-10-27','NSRP'),(11600,18439,'peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine','P','The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester.','2013-10-27','NSRP'),(11601,18441,'iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide','P','The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.','2013-10-27','NSRP'),(11602,18442,'peptidyl-glutamic acid esterification','P','The addition of an ester group to a glutamic acid residue in a protein.','2013-10-27','NSRP'),(11603,18443,'enzyme active site formation via L-aspartic 4-phosphoric anhydride','P','The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride.','2013-10-27','NSRP'),(11604,18444,'translation release factor complex','C','A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.','2013-10-27','NSRP'),(11605,18445,'prothoracicotrophic hormone activity','F','The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.','2013-10-27','NSRP'),(11606,18446,'pinocarveol dehydrogenase activity','F','Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.','2013-10-27','NSRP'),(11607,18447,'chloral hydrate dehydrogenase activity','F','Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.','2013-10-27','NSRP'),(11608,18448,'hydroxymethylmethylsilanediol oxidase activity','F','Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.','2013-10-27','NSRP'),(11609,18449,'1-phenylethanol dehydrogenase activity','F','Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.','2013-10-27','NSRP'),(11610,18450,'myrtenol dehydrogenase activity','F','Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.','2013-10-27','NSRP'),(11611,18451,'epoxide dehydrogenase activity','F','Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA.','2013-10-27','NSRP'),(11612,18452,'5-exo-hydroxycamphor dehydrogenase activity','F','Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.','2013-10-27','NSRP'),(11613,18453,'2-hydroxytetrahydrofuran dehydrogenase activity','F','Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone.','2013-10-27','NSRP'),(11614,18454,'acetoacetyl-CoA reductase activity','F','Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.','2013-10-27','NSRP'),(11615,18455,'alcohol dehydrogenase [NAD(P)+] activity','F','Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.','2013-10-27','NSRP'),(11616,18456,'aryl-alcohol dehydrogenase (NAD+) activity','F','Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.','2013-10-27','NSRP'),(11617,18457,'perillyl-alcohol dehydrogenase activity','F','Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde.','2013-10-27','NSRP'),(11618,18458,'isopiperitenol dehydrogenase activity','F','Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH.','2013-10-27','NSRP'),(11619,18459,'carveol dehydrogenase activity','F','Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH.','2013-10-27','NSRP'),(11620,18460,'cyclohexanol dehydrogenase activity','F','Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.','2013-10-27','NSRP'),(11621,18461,'fluoren-9-ol dehydrogenase activity','F','Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.','2013-10-27','NSRP'),(11622,18462,'4-(hydroxymethyl)benzenesulfonate dehydrogenase activity','F','Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH.','2013-10-27','NSRP'),(11623,18463,'6-hydroxyhexanoate dehydrogenase activity','F','Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH.','2013-10-27','NSRP'),(11624,18464,'3-hydroxypimeloyl-CoA dehydrogenase activity','F','Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH.','2013-10-27','NSRP'),(11625,18465,'vanillyl-alcohol oxidase activity','F','Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin.','2013-10-27','NSRP'),(11626,18466,'limonene-1,2-diol dehydrogenase activity','F','Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.','2013-10-27','NSRP'),(11627,18467,'formaldehyde dehydrogenase activity','F','Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.','2013-10-27','NSRP'),(11628,18468,'alcohol dehydrogenase (acceptor) activity','F','Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor.','2013-10-27','NSRP'),(11629,18469,'myrtenal dehydrogenase activity','F','Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.','2013-10-27','NSRP'),(11630,18470,'4-hydroxybutaraldehyde dehydrogenase activity','F','Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.','2013-10-27','NSRP'),(11631,18471,'4-chlorobenzaldehyde oxidase activity','F','Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.','2013-10-27','NSRP'),(11632,18472,'1-hydroxy-2-naphthaldehyde dehydrogenase activity','F','Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.','2013-10-27','NSRP'),(11633,18473,'cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity','F','Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.','2013-10-27','NSRP'),(11634,18474,'2-carboxybenzaldehyde dehydrogenase activity','F','Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.','2013-10-27','NSRP'),(11635,18475,'trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity','F','Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.','2013-10-27','NSRP'),(11636,18477,'benzaldehyde dehydrogenase (NADP+) activity','F','Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.','2013-10-27','NSRP'),(11637,18478,'malonate-semialdehyde dehydrogenase (acetylating) activity','F','Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+.','2013-10-27','NSRP'),(11638,18479,'benzaldehyde dehydrogenase (NAD+) activity','F','Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.','2013-10-27','NSRP'),(11639,18480,'5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity','F','Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.','2013-10-27','NSRP'),(11640,18481,'4-hydroxymuconic-semialdehyde dehydrogenase activity','F','Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH.','2013-10-27','NSRP'),(11641,18482,'4-formylbenzenesulfonate dehydrogenase activity','F','Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH.','2013-10-27','NSRP'),(11642,18483,'6-oxohexanoate dehydrogenase activity','F','Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.','2013-10-27','NSRP'),(11643,18484,'4-hydroxybenzaldehyde dehydrogenase activity','F','Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.','2013-10-27','NSRP'),(11644,18485,'salicylaldehyde dehydrogenase activity','F','Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.','2013-10-27','NSRP'),(11645,18486,'2-butanone oxidase activity','F','Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate.','2013-10-27','NSRP'),(11646,18487,'vanillate O-demethylase (anaerobic) activity','F','Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.','2013-10-27','NSRP'),(11647,18488,'aryl-aldehyde oxidase activity','F','Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.','2013-10-27','NSRP'),(11648,18489,'vanillate monooxygenase activity','F','Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+).','2013-10-27','NSRP'),(11649,18490,'4-hydroxyphenylpyruvate oxidase activity','F','Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2).','2013-10-27','NSRP'),(11650,18491,'2-oxobutyrate synthase activity','F','Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.','2013-10-27','NSRP'),(11651,18492,'carbon-monoxide dehydrogenase (acceptor) activity','F','Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.','2013-10-27','NSRP'),(11652,18493,'formylmethanofuran dehydrogenase activity','F','Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran.','2013-10-27','NSRP'),(11653,18494,'carvone reductase activity','F','Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.','2013-10-27','NSRP'),(11654,18495,'2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity','F','Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.','2013-10-27','NSRP'),(11655,18496,'2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity','F','Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.','2013-10-27','NSRP'),(11656,18497,'1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity','F','Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.','2013-10-27','NSRP'),(11657,18498,'2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity','F','Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.','2013-10-27','NSRP'),(11658,18499,'cis-2,3-dihydrodiol DDT dehydrogenase activity','F','Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.','2013-10-27','NSRP'),(11659,18500,'trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity','F','Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.','2013-10-27','NSRP'),(11660,18501,'cis-chlorobenzene dihydrodiol dehydrogenase activity','F','Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.','2013-10-27','NSRP'),(11661,18502,'2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity','F','Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.','2013-10-27','NSRP'),(11662,18503,'trans-1,2-dihydrodiolphenanthrene dehydrogenase activity','F','Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.','2013-10-27','NSRP'),(11663,18504,'cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.','2013-10-27','NSRP'),(11664,18505,'cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.','2013-10-27','NSRP'),(11665,18506,'maleylacetate reductase activity','F','Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.','2013-10-27','NSRP'),(11666,18507,'cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity','F','Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol.','2013-10-27','NSRP'),(11667,18508,'cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.','2013-10-27','NSRP'),(11668,18509,'cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity','F','Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.','2013-10-27','NSRP'),(11669,18510,'phloroglucinol reductase activity','F','Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol.','2013-10-27','NSRP'),(11670,18511,'2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity','F','Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH.','2013-10-27','NSRP'),(11671,18512,'1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate dehydrogenase activity','F','OBSOLETE. Catalysis of the reaction: 1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ = 3-methylcatechol + CO2 + NADH + H+.','2013-10-27','NSRP'),(11672,18513,'dibenzothiophene dihydrodiol dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH.','2013-10-27','NSRP'),(11673,18515,'pimeloyl-CoA dehydrogenase activity','F','Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH.','2013-10-27','NSRP'),(11674,18516,'2,4-dichlorobenzoyl-CoA reductase activity','F','Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH.','2013-10-27','NSRP'),(11675,18517,'phthalate 4,5-cis-dihydrodiol dehydrogenase activity','F','Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH.','2013-10-27','NSRP'),(11676,18518,'5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity','F','Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH.','2013-10-27','NSRP'),(11677,18519,'cis-dihydroethylcatechol dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH.','2013-10-27','NSRP'),(11678,18520,'cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity','F','Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.','2013-10-27','NSRP'),(11679,18521,'1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity','F','Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH.','2013-10-27','NSRP'),(11680,18522,'benzoyl-CoA reductase activity','F','Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin.','2013-10-27','NSRP'),(11681,18523,'quinoline 2-oxidoreductase activity','F','Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.','2013-10-27','NSRP'),(11682,18524,'acetophenone carboxylase activity','F','Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.','2013-10-27','NSRP'),(11683,18525,'4-hydroxybenzoyl-CoA reductase activity','F','Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.','2013-10-27','NSRP'),(11684,18526,'2-aminobenzoyl-CoA reductase activity','F','Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.','2013-10-27','NSRP'),(11685,18527,'cyclohexylamine oxidase activity','F','Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide.','2013-10-27','NSRP'),(11686,18528,'iminodiacetate dehydrogenase activity','F','Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.','2013-10-27','NSRP'),(11687,18529,'nitrilotriacetate monooxygenase activity','F','Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.','2013-10-27','NSRP'),(11688,18530,'(R)-6-hydroxynicotine oxidase activity','F','Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).','2013-10-27','NSRP'),(11689,18531,'(S)-6-hydroxynicotine oxidase activity','F','Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).','2013-10-27','NSRP'),(11690,18532,'5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity','F','Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.','2013-10-27','NSRP'),(11691,18533,'peptidyl-cysteine acetylation','P','The acetylation of peptidyl-cysteine.','2013-10-27','NSRP'),(11692,18534,'nitrilotriacetate dehydrogenase activity','F','Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.','2013-10-27','NSRP'),(11693,18535,'nicotine dehydrogenase activity','F','Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.','2013-10-27','NSRP'),(11694,18537,'coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity','F','Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.','2013-10-27','NSRP'),(11695,18538,'epoxide carboxylase activity','F','Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.','2013-10-27','NSRP'),(11696,18541,'p-benzoquinone reductase (NADPH) activity','F','Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+).','2013-10-27','NSRP'),(11697,18542,'2,3-dihydroxy DDT 1,2-dioxygenase activity','F','Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.','2013-10-27','NSRP'),(11698,18543,'4-amino-2-nitroso-6-nitrotoluene reductase activity','F','Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.','2013-10-27','NSRP'),(11699,18544,'4-carboxy-4\'-sulfoazobenzene reductase activity','F','Catalysis of the reaction: 4-carboxy-4\'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.','2013-10-27','NSRP'),(11700,18545,'NAD(P)H nitroreductase activity','F','Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.','2013-10-27','NSRP'),(11701,18546,'nitrobenzene nitroreductase activity','F','Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.','2013-10-27','NSRP'),(11702,18547,'nitroglycerin reductase activity','F','Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.','2013-10-27','NSRP'),(11703,18548,'pentaerythritol trinitrate reductase activity','F','Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.','2013-10-27','NSRP'),(11704,18549,'methanethiol oxidase activity','F','Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.','2013-10-27','NSRP'),(11705,18550,'tetrachloro-p-hydroquinone reductive dehalogenase activity','F','Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.','2013-10-27','NSRP'),(11706,18551,'hydrogensulfite reductase activity','F','Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.','2013-10-27','NSRP'),(11707,18553,'3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity','F','Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.','2013-10-27','NSRP'),(11708,18554,'1,2-dihydroxynaphthalene dioxygenase activity','F','Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.','2013-10-27','NSRP'),(11709,18555,'phenanthrene dioxygenase activity','F','Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.','2013-10-27','NSRP'),(11710,18556,'2,2\',3-trihydroxybiphenyl dioxygenase activity','F','Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2\',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2\',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).','2013-10-27','NSRP'),(11711,18557,'1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity','F','Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.','2013-10-27','NSRP'),(11712,18558,'5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity','F','Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.','2013-10-27','NSRP'),(11713,18559,'1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity','F','Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4\'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.','2013-10-27','NSRP'),(11714,18560,'protocatechuate 3,4-dioxygenase type II activity','F','Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate.','2013-10-27','NSRP'),(11715,18561,'2\'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity','F','Catalysis of the reaction: 2\'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2\'-aminophenyl)-hexa-2,4-dienoate.','2013-10-27','NSRP'),(11716,18562,'3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity','F','Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.','2013-10-27','NSRP'),(11717,18563,'2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity','F','Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.','2013-10-27','NSRP'),(11718,18564,'carbazole 1,9a-dioxygenase activity','F','Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2\'-aminobiphenyl-2,3-diol.','2013-10-27','NSRP'),(11719,18565,'dihydroxydibenzothiophene dioxygenase activity','F','Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.','2013-10-27','NSRP'),(11720,18566,'1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity','F','Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.','2013-10-27','NSRP'),(11721,18567,'styrene dioxygenase activity','F','Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.','2013-10-27','NSRP'),(11722,18568,'3,4-dihydroxyphenanthrene dioxygenase activity','F','Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.','2013-10-27','NSRP'),(11723,18569,'hydroquinone 1,2-dioxygenase activity','F','Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.','2013-10-27','NSRP'),(11724,18570,'p-cumate 2,3-dioxygenase activity','F','Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.','2013-10-27','NSRP'),(11725,18571,'2,3-dihydroxy-p-cumate dioxygenase activity','F','Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.','2013-10-27','NSRP'),(11726,18572,'3,5-dichlorocatechol 1,2-dioxygenase activity','F','Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate.','2013-10-27','NSRP'),(11727,18573,'2-aminophenol 1,6-dioxygenase activity','F','Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde.','2013-10-27','NSRP'),(11728,18574,'2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity','F','Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.','2013-10-27','NSRP'),(11729,18575,'chlorocatechol 1,2-dioxygenase activity','F','Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.','2013-10-27','NSRP'),(11730,18576,'catechol 1,2-dioxygenase activity','F','Catalysis of the reaction: catechol + O2 = cis,cis-muconate.','2013-10-27','NSRP'),(11731,18577,'catechol 2,3-dioxygenase activity','F','Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.','2013-10-27','NSRP'),(11732,18578,'protocatechuate 3,4-dioxygenase activity','F','Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.','2013-10-27','NSRP'),(11733,18579,'protocatechuate 4,5-dioxygenase activity','F','Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.','2013-10-27','NSRP'),(11734,18580,'nitronate monooxygenase activity','F','Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite.','2013-10-27','NSRP'),(11735,18581,'hydroxyquinol 1,2-dioxygenase activity','F','Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.','2013-10-27','NSRP'),(11736,18582,'1-hydroxy-2-naphthoate 1,2-dioxygenase activity','F','Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.','2013-10-27','NSRP'),(11737,18583,'biphenyl-2,3-diol 1,2-dioxygenase activity','F','Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.','2013-10-27','NSRP'),(11738,18584,'2,4,5-trichlorophenoxyacetic acid oxygenase activity','F','Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.','2013-10-27','NSRP'),(11739,18585,'fluorene oxygenase activity','F','Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.','2013-10-27','NSRP'),(11740,18586,'mono-butyltin dioxygenase activity','F','Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin.','2013-10-27','NSRP'),(11741,18587,'limonene 8-monooxygenase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11742,18588,'tri-n-butyltin dioxygenase activity','F','Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin.','2013-10-27','NSRP'),(11743,18589,'di-n-butyltin dioxygenase activity','F','Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.','2013-10-27','NSRP'),(11744,18590,'methylsilanetriol hydroxylase activity','F','Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.','2013-10-27','NSRP'),(11745,18591,'methyl tertiary butyl ether 3-monooxygenase activity','F','Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde.','2013-10-27','NSRP'),(11746,18592,'4-nitrocatechol 4-monooxygenase activity','F','Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.','2013-10-27','NSRP'),(11747,18593,'4-chlorophenoxyacetate monooxygenase activity','F','Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol.','2013-10-27','NSRP'),(11748,18594,'tert-butanol 2-monooxygenase activity','F','Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol.','2013-10-27','NSRP'),(11749,18595,'alpha-pinene monooxygenase activity','F','Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol.','2013-10-27','NSRP'),(11750,18596,'dimethylsilanediol hydroxylase activity','F','Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.','2013-10-27','NSRP'),(11751,18597,'ammonia monooxygenase activity','F','Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.','2013-10-27','NSRP'),(11752,18598,'hydroxymethylsilanetriol oxidase activity','F','Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol.','2013-10-27','NSRP'),(11753,18599,'2-hydroxyisobutyrate 3-monooxygenase activity','F','Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate.','2013-10-27','NSRP'),(11754,18600,'alpha-pinene dehydrogenase activity','F','Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol.','2013-10-27','NSRP'),(11755,18601,'4-nitrophenol 2-monooxygenase activity','F','Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+).','2013-10-27','NSRP'),(11756,18602,'2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity','F','Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.','2013-10-27','NSRP'),(11757,18603,'nitrobenzene 1,2-dioxygenase activity','F','Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.','2013-10-27','NSRP'),(11758,18604,'4-aminobenzoate 3,4-dioxygenase (deaminating) activity','F','Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate.','2013-10-27','NSRP'),(11759,18606,'benzenesulfonate dioxygenase activity','F','Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.','2013-10-27','NSRP'),(11760,18607,'1-indanone monooxygenase activity','F','Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.','2013-10-27','NSRP'),(11761,18608,'1-indanone dioxygenase activity','F','Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.','2013-10-27','NSRP'),(11762,18609,'chlorobenzene dioxygenase activity','F','Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).','2013-10-27','NSRP'),(11763,18610,'dibenzofuran 4,4a-dioxygenase activity','F','Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2\',3-trihydroxybiphenyl + NAD+.','2013-10-27','NSRP'),(11764,18611,'toluate dioxygenase activity','F','Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.','2013-10-27','NSRP'),(11765,18612,'dibenzothiophene dioxygenase activity','F','Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.','2013-10-27','NSRP'),(11766,18613,'9-fluorenone dioxygenase activity','F','Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.','2013-10-27','NSRP'),(11767,18614,'ethylbenzene dioxygenase activity','F','Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.','2013-10-27','NSRP'),(11768,18615,'2-indanone monooxygenase activity','F','Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone.','2013-10-27','NSRP'),(11769,18616,'trihydroxytoluene dioxygenase activity','F','Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.','2013-10-27','NSRP'),(11770,18617,'4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity','F','Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol.','2013-10-27','NSRP'),(11771,18618,'anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity','F','Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.','2013-10-27','NSRP'),(11772,18619,'benzene 1,2-dioxygenase activity','F','Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).','2013-10-27','NSRP'),(11773,18620,'phthalate 4,5-dioxygenase activity','F','Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+).','2013-10-27','NSRP'),(11774,18621,'4-sulfobenzoate 3,4-dioxygenase activity','F','Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite.','2013-10-27','NSRP'),(11775,18622,'4-chlorophenylacetate 3,4-dioxygenase activity','F','Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+).','2013-10-27','NSRP'),(11776,18623,'benzoate 1,2-dioxygenase activity','F','Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.','2013-10-27','NSRP'),(11777,18624,'toluene dioxygenase activity','F','Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).','2013-10-27','NSRP'),(11778,18625,'naphthalene 1,2-dioxygenase activity','F','Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.','2013-10-27','NSRP'),(11779,18626,'2-chlorobenzoate 1,2-dioxygenase activity','F','Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.','2013-10-27','NSRP'),(11780,18627,'2-aminobenzenesulfonate 2,3-dioxygenase activity','F','Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.','2013-10-27','NSRP'),(11781,18628,'terephthalate 1,2-dioxygenase activity','F','Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+).','2013-10-27','NSRP'),(11782,18629,'2-hydroxyquinoline 5,6-dioxygenase activity','F','Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.','2013-10-27','NSRP'),(11783,18630,'3,5-xylenol methylhydroxylase activity','F','Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.','2013-10-27','NSRP'),(11784,18631,'phenylacetate hydroxylase activity','F','Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate.','2013-10-27','NSRP'),(11785,18632,'4-nitrophenol 4-monooxygenase activity','F','Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.','2013-10-27','NSRP'),(11786,18633,'dimethyl sulfide monooxygenase activity','F','Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.','2013-10-27','NSRP'),(11787,18634,'alpha-pinene monooxygenase [NADH] activity','F','Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.','2013-10-27','NSRP'),(11788,18635,'(R)-limonene 1,2-monooxygenase activity','F','Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.','2013-10-27','NSRP'),(11789,18636,'phenanthrene 9,10-monooxygenase activity','F','Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.','2013-10-27','NSRP'),(11790,18637,'1-hydroxy-2-naphthoate hydroxylase activity','F','Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.','2013-10-27','NSRP'),(11791,18638,'toluene 4-monooxygenase activity','F','Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene.','2013-10-27','NSRP'),(11792,18639,'xylene monooxygenase activity','F','Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.','2013-10-27','NSRP'),(11793,18640,'dibenzothiophene monooxygenase activity','F','Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.','2013-10-27','NSRP'),(11794,18641,'6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity','F','Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.','2013-10-27','NSRP'),(11795,18642,'chlorophenol 4-monooxygenase activity','F','Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.','2013-10-27','NSRP'),(11796,18643,'carbon disulfide oxygenase activity','F','Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.','2013-10-27','NSRP'),(11797,18644,'toluene 2-monooxygenase activity','F','Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene.','2013-10-27','NSRP'),(11798,18645,'alkene monooxygenase activity','F','Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.','2013-10-27','NSRP'),(11799,18646,'1-hydroxy-2-oxolimonene 1,2-monooxygenase activity','F','Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.','2013-10-27','NSRP'),(11800,18647,'phenanthrene 1,2-monooxygenase activity','F','Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.','2013-10-27','NSRP'),(11801,18648,'methanesulfonate monooxygenase activity','F','Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.','2013-10-27','NSRP'),(11802,18649,'tetrahydrofuran hydroxylase activity','F','Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran.','2013-10-27','NSRP'),(11803,18650,'styrene monooxygenase activity','F','Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.','2013-10-27','NSRP'),(11804,18651,'toluene-4-sulfonate monooxygenase activity','F','Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene.','2013-10-27','NSRP'),(11805,18652,'toluene-sulfonate methyl-monooxygenase activity','F','Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.','2013-10-27','NSRP'),(11806,18653,'3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity','F','Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.','2013-10-27','NSRP'),(11807,18654,'2-hydroxy-phenylacetate hydroxylase activity','F','Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate.','2013-10-27','NSRP'),(11808,18655,'2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity','F','Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.','2013-10-27','NSRP'),(11809,18656,'phenanthrene 3,4-monooxygenase activity','F','Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide.','2013-10-27','NSRP'),(11810,18657,'toluene 3-monooxygenase activity','F','Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene.','2013-10-27','NSRP'),(11811,18658,'salicylate 1-monooxygenase activity','F','Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.','2013-10-27','NSRP'),(11812,18659,'4-hydroxybenzoate 3-monooxygenase activity','F','Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.','2013-10-27','NSRP'),(11813,18660,'4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity','F','Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.','2013-10-27','NSRP'),(11814,18661,'orcinol 2-monooxygenase activity','F','Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+).','2013-10-27','NSRP'),(11815,18662,'phenol 2-monooxygenase activity','F','Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.','2013-10-27','NSRP'),(11816,18663,'2,6-dihydroxypyridine 3-monooxygenase activity','F','Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+).','2013-10-27','NSRP'),(11817,18664,'benzoate 4-monooxygenase activity','F','Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+).','2013-10-27','NSRP'),(11818,18665,'4-hydroxyphenylacetate 1-monooxygenase activity','F','Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.','2013-10-27','NSRP'),(11819,18666,'2,4-dichlorophenol 6-monooxygenase activity','F','Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.','2013-10-27','NSRP'),(11820,18667,'cyclohexanone monooxygenase activity','F','Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.','2013-10-27','NSRP'),(11821,18668,'3-hydroxybenzoate 4-monooxygenase activity','F','Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+).','2013-10-27','NSRP'),(11822,18669,'3-hydroxybenzoate 6-monooxygenase activity','F','Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+).','2013-10-27','NSRP'),(11823,18670,'4-aminobenzoate 1-monooxygenase activity','F','Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.','2013-10-27','NSRP'),(11824,18671,'4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity','F','Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.','2013-10-27','NSRP'),(11825,18672,'anthranilate 3-monooxygenase (deaminating) activity','F','Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+).','2013-10-27','NSRP'),(11826,18673,'anthraniloyl-CoA monooxygenase activity','F','Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.','2013-10-27','NSRP'),(11827,18674,'(S)-limonene 3-monooxygenase activity','F','Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+).','2013-10-27','NSRP'),(11828,18675,'(S)-limonene 6-monooxygenase activity','F','Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O.','2013-10-27','NSRP'),(11829,18676,'(S)-limonene 7-monooxygenase activity','F','Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+).','2013-10-27','NSRP'),(11830,18677,'pentachlorophenol monooxygenase activity','F','Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.','2013-10-27','NSRP'),(11831,18678,'4-hydroxybenzoate 1-hydroxylase activity','F','Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.','2013-10-27','NSRP'),(11832,18679,'dibenzothiophene-5,5-dioxide monooxygenase activity','F','Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2\'-hydroxybiphenyl-2-sulfinate.','2013-10-27','NSRP'),(11833,18680,'deethylatrazine monooxygenase activity','F','Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.','2013-10-27','NSRP'),(11834,18681,'deisopropylatrazine monooxygenase activity','F','Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.','2013-10-27','NSRP'),(11835,18682,'atrazine N-dealkylase activity','F','Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.','2013-10-27','NSRP'),(11836,18683,'camphor 5-monooxygenase activity','F','Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.','2013-10-27','NSRP'),(11837,18684,'camphor 1,2-monooxygenase activity','F','Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O.','2013-10-27','NSRP'),(11838,18685,'alkane 1-monooxygenase activity','F','Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.','2013-10-27','NSRP'),(11839,18686,'6-hydroxy pseudo-oxynicotine monooxygenase activity','F','Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.','2013-10-27','NSRP'),(11840,18687,'biphenyl 2,3-dioxygenase activity','F','Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.','2013-10-27','NSRP'),(11841,18688,'DDT 2,3-dioxygenase activity','F','Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.','2013-10-27','NSRP'),(11842,18689,'naphthalene disulfonate 1,2-dioxygenase activity','F','Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).','2013-10-27','NSRP'),(11843,18690,'4-methoxybenzoate monooxygenase (O-demethylating) activity','F','Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O.','2013-10-27','NSRP'),(11844,18693,'ethylbenzene hydroxylase activity','F','Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2).','2013-10-27','NSRP'),(11845,18694,'p-cymene methyl hydroxylase activity','F','Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.','2013-10-27','NSRP'),(11846,18695,'4-cresol dehydrogenase (hydroxylating) activity','F','Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.','2013-10-27','NSRP'),(11847,18697,'carbonyl sulfide nitrogenase activity','F','Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.','2013-10-27','NSRP'),(11848,18698,'vinyl chloride reductive dehalogenase activity','F','Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.','2013-10-27','NSRP'),(11849,18699,'1,1,1-trichloroethane reductive dehalogenase activity','F','Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.','2013-10-27','NSRP'),(11850,18700,'2-chloro-N-isopropylacetanilide reductive dehalogenase activity','F','Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.','2013-10-27','NSRP'),(11851,18701,'2,5-dichlorohydroquinone reductive dehalogenase activity','F','Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).','2013-10-27','NSRP'),(11852,18702,'1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity','F','Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.','2013-10-27','NSRP'),(11853,18703,'2,4-dichlorophenoxyacetate dehalogenase activity','F','Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.','2013-10-27','NSRP'),(11854,18704,'5-chloro-2-hydroxymuconic semialdehyde dehalogenase activity','F','Catalysis of the reaction: 5-chloro-2-hydroxymuconic semialdehyde + H+ + 2 e- = Cl- + 2-hydroxymuconic semialdehyde.','2013-10-27','NSRP'),(11855,18705,'1,2-dichloroethene reductive dehalogenase activity','F','Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.','2013-10-27','NSRP'),(11856,18706,'pyrogallol hydroxytransferase activity','F','Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.','2013-10-27','NSRP'),(11857,18707,'1-phenanthrol methyltransferase activity','F','Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.','2013-10-27','NSRP'),(11858,18708,'thiol S-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.','2013-10-27','NSRP'),(11859,18710,'acetone carboxylase activity','F','Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate.','2013-10-27','NSRP'),(11860,18711,'benzoyl acetate-CoA thiolase activity','F','Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA.','2013-10-27','NSRP'),(11861,18712,'3-hydroxybutyryl-CoA thiolase activity','F','Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.','2013-10-27','NSRP'),(11862,18713,'3-ketopimelyl-CoA thiolase activity','F','Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.','2013-10-27','NSRP'),(11863,18715,'9-phenanthrol UDP-glucuronosyltransferase activity','F','Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.','2013-10-27','NSRP'),(11864,18716,'1-phenanthrol glycosyltransferase activity','F','Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.','2013-10-27','NSRP'),(11865,18717,'9-phenanthrol glycosyltransferase activity','F','Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O.','2013-10-27','NSRP'),(11866,18718,'1,2-dihydroxy-phenanthrene glycosyltransferase activity','F','Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.','2013-10-27','NSRP'),(11867,18719,'6-aminohexanoate transaminase activity','F','Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate.','2013-10-27','NSRP'),(11868,18720,'phenol kinase activity','F','Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.','2013-10-27','NSRP'),(11869,18721,'trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity','F','Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.','2013-10-27','NSRP'),(11870,18722,'1-phenanthrol sulfotransferase activity','F','Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.','2013-10-27','NSRP'),(11871,18723,'3-phenanthrol sulfotransferase activity','F','Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate.','2013-10-27','NSRP'),(11872,18724,'4-phenanthrol sulfotransferase activity','F','Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.','2013-10-27','NSRP'),(11873,18725,'trans-3,4-dihydrodiolphenanthrene sulfotransferase activity','F','Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.','2013-10-27','NSRP'),(11874,18726,'9-phenanthrol sulfotransferase activity','F','Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.','2013-10-27','NSRP'),(11875,18727,'2-phenanthrol sulfotransferase activity','F','Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.','2013-10-27','NSRP'),(11876,18729,'propionate CoA-transferase activity','F','Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.','2013-10-27','NSRP'),(11877,18730,'glutaconate CoA-transferase activity','F','Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.','2013-10-27','NSRP'),(11878,18731,'1-oxa-2-oxocycloheptane lactonase activity','F','Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.','2013-10-27','NSRP'),(11879,18732,'sulfolactone hydrolase activity','F','Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.','2013-10-27','NSRP'),(11880,18733,'3,4-dihydrocoumarin hydrolase activity','F','Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.','2013-10-27','NSRP'),(11881,18734,'butyrolactone hydrolase activity','F','Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.','2013-10-27','NSRP'),(11882,18736,'6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity','F','Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.','2013-10-27','NSRP'),(11883,18737,'2-ketocyclohexane-1-carboxyl-CoA hydrolase activity','F','Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.','2013-10-27','NSRP'),(11884,18738,'S-formylglutathione hydrolase activity','F','Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+).','2013-10-27','NSRP'),(11885,18739,'4-hydroxybenzoyl-CoA thioesterase activity','F','Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+).','2013-10-27','NSRP'),(11886,18740,'2\'-hydroxybiphenyl-2-sulfinate desulfinase activity','F','Catalysis of the reaction: 2\'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite.','2013-10-27','NSRP'),(11887,18741,'alkyl sulfatase activity','F','Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol.','2013-10-27','NSRP'),(11888,18742,'epoxide hydrolase B activity','F','Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.','2013-10-27','NSRP'),(11889,18743,'phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity','F','Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.','2013-10-27','NSRP'),(11890,18744,'limonene-1,2-epoxide hydrolase activity','F','Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.','2013-10-27','NSRP'),(11891,18745,'epoxide hydrolase A activity','F','Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.','2013-10-27','NSRP'),(11892,18746,'phenanthrene-3,4-epoxide hydrolase activity','F','Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.','2013-10-27','NSRP'),(11893,18747,'phenanthrene-1,2-epoxide hydrolase activity','F','Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.','2013-10-27','NSRP'),(11894,18748,'iprodione amidohydrolase activity','F','Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate.','2013-10-27','NSRP'),(11895,18749,'(3,5-dichlorophenylurea)acetate amidohydrolase activity','F','Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.','2013-10-27','NSRP'),(11896,18750,'biuret amidohydrolase activity','F','Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.','2013-10-27','NSRP'),(11897,18751,'3,5-dichlorophenylcarboximide hydrolase activity','F','Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.','2013-10-27','NSRP'),(11898,18752,'epsilon-caprolactam lactamase activity','F','Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.','2013-10-27','NSRP'),(11899,18753,'cyanuric acid amidohydrolase activity','F','Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2.','2013-10-27','NSRP'),(11900,18754,'ammelide aminohydrolase activity','F','Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.','2013-10-27','NSRP'),(11901,18755,'2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity','F','Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.','2013-10-27','NSRP'),(11902,18756,'ammeline aminohydrolase activity','F','Catalysis of the reaction: ammeline + H2O = ammelide + NH3.','2013-10-27','NSRP'),(11903,18757,'deisopropylhydroxyatrazine aminohydrolase activity','F','Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N\'-ethyl)amino-1,3,5-triazine.','2013-10-27','NSRP'),(11904,18758,'2,4-dihydroxy-6-(N\'-ethyl)amino-1,3,5-triazine aminohydrolase activity','F','Catalysis of the reaction: 2,4-dihydroxy-6-(N\'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.','2013-10-27','NSRP'),(11905,18759,'methenyltetrahydromethanopterin cyclohydrolase activity','F','Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+).','2013-10-27','NSRP'),(11906,18760,'thiocyanate hydrolase activity','F','Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+).','2013-10-27','NSRP'),(11907,18761,'bromoxynil nitrilase activity','F','Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil.','2013-10-27','NSRP'),(11908,18762,'aliphatic nitrilase activity','F','Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.','2013-10-27','NSRP'),(11909,18763,'hydroxydechloroatrazine ethylaminohydrolase activity','F','Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.','2013-10-27','NSRP'),(11910,18764,'N-isopropylammelide isopropylaminohydrolase activity','F','Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.','2013-10-27','NSRP'),(11911,18765,'2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity','F','Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.','2013-10-27','NSRP'),(11912,18766,'dihydrophloroglucinol hydrolase activity','F','Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.','2013-10-27','NSRP'),(11913,18767,'2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity','F','Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.','2013-10-27','NSRP'),(11914,18768,'2-hydroxy-6-oxo-6-(2\'-aminophenyl)hexa-2,4-dienoate hydrolase activity','F','Catalysis of the reaction: 2-hydroxy-6-oxo-(2\'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.','2013-10-27','NSRP'),(11915,18769,'2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity','F','Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.','2013-10-27','NSRP'),(11916,18770,'6-oxo-2-hydroxy-7-(4\'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity','F','Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4\'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4\'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.','2013-10-27','NSRP'),(11917,18771,'2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity','F','Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.','2013-10-27','NSRP'),(11918,18772,'trioxoheptanoate hydrolase activity','F','Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.','2013-10-27','NSRP'),(11919,18773,'acetylpyruvate hydrolase activity','F','Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate.','2013-10-27','NSRP'),(11920,18774,'2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity','F','Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate.','2013-10-27','NSRP'),(11921,18775,'2-hydroxymuconate-semialdehyde hydrolase activity','F','Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.','2013-10-27','NSRP'),(11922,18776,'trans-chloroacrylic acid dehalogenase activity','F','Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde.','2013-10-27','NSRP'),(11923,18777,'1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity','F','Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).','2013-10-27','NSRP'),(11924,18778,'DL-2 haloacid dehalogenase activity','F','Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.','2013-10-27','NSRP'),(11925,18779,'2-chloro-4,6-dihydroxy-1,3,5-triazine hydrolase activity','F','OBSOLETE (was not defined before being made obsolete).','2013-10-27','NSRP'),(11926,18780,'dichloroacetate halidohydrolase activity','F','Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate.','2013-10-27','NSRP'),(11927,18781,'S-triazine hydrolase activity','F','Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.','2013-10-27','NSRP'),(11928,18782,'cis-chloroacrylic acid dehalogenase activity','F','Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde.','2013-10-27','NSRP'),(11929,18783,'deisopropyldeethylatrazine hydrolase activity','F','Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.','2013-10-27','NSRP'),(11930,18784,'(S)-2-haloacid dehalogenase activity','F','Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.','2013-10-27','NSRP'),(11931,18785,'haloacetate dehalogenase activity','F','Catalysis of the reaction: haloacetate + H2O = glycolate + halide.','2013-10-27','NSRP'),(11932,18786,'haloalkane dehalogenase activity','F','Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.','2013-10-27','NSRP'),(11933,18787,'4-chlorobenzoyl-CoA dehalogenase activity','F','Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.','2013-10-27','NSRP'),(11934,18788,'atrazine chlorohydrolase activity','F','Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+).','2013-10-27','NSRP'),(11935,18789,'cyclamate sulfohydrolase activity','F','Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate.','2013-10-27','NSRP'),(11936,18791,'2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity','F','Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.','2013-10-27','NSRP'),(11937,18792,'bis(4-chlorophenyl)acetate decarboxylase activity','F','Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.','2013-10-27','NSRP'),(11938,18793,'3,5-dibromo-4-hydroxybenzoate decarboxylase activity','F','Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.','2013-10-27','NSRP'),(11939,18794,'2-hydroxyisobutyrate decarboxylase activity','F','Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.','2013-10-27','NSRP'),(11940,18795,'2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity','F','Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.','2013-10-27','NSRP'),(11941,18796,'4,5-dihydroxyphthalate decarboxylase activity','F','Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.','2013-10-27','NSRP'),(11942,18798,'gallate decarboxylase activity','F','Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol.','2013-10-27','NSRP'),(11943,18799,'4-hydroxybenzoate decarboxylase activity','F','Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol.','2013-10-27','NSRP'),(11944,18800,'5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity','F','Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.','2013-10-27','NSRP'),(11945,18801,'glutaconyl-CoA decarboxylase activity','F','Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2).','2013-10-27','NSRP'),(11946,18802,'2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity','F','Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.','2013-10-27','NSRP'),(11947,18803,'4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity','F','Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.','2013-10-27','NSRP'),(11948,18805,'benzylsuccinate synthase activity','F','Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.','2013-10-27','NSRP'),(11949,18807,'6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity','F','Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.','2013-10-27','NSRP'),(11950,18808,'trans-4-(1\'-hydroxynaphth-2\'-yl)-2-oxobut-3-enoate hydratase-aldolase activity','F','Catalysis of the reaction: trans-4-(1\'-hydroxynaphth-2\'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.','2013-10-27','NSRP'),(11951,18809,'E-phenylitaconyl-CoA hydratase activity','F','Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA.','2013-10-27','NSRP'),(11952,18810,'trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity','F','Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.','2013-10-27','NSRP'),(11953,18811,'cyclohex-1-ene-1-carboxyl-CoA hydratase activity','F','Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.','2013-10-27','NSRP'),(11954,18812,'3-hydroxyacyl-CoA dehydratase activity','F','Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).','2013-10-27','NSRP'),(11955,18813,'trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity','F','Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).','2013-10-27','NSRP'),(11956,18814,'phenylacetaldoxime dehydratase activity','F','Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile.','2013-10-27','NSRP'),(11957,18815,'3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity','F','Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.','2013-10-27','NSRP'),(11958,18816,'2-hydroxyisobutyrate dehydratase activity','F','Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.','2013-10-27','NSRP'),(11959,18817,'2-oxo-hept-3-ene-1,7-dioate hydratase activity','F','Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.','2013-10-27','NSRP'),(11960,18818,'acetylene hydratase activity','F','Catalysis of the reaction: acetaldehyde = acetylene + H(2)O.','2013-10-27','NSRP'),(11961,18819,'lactoyl-CoA dehydratase activity','F','Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.','2013-10-27','NSRP'),(11962,18820,'cyanamide hydratase activity','F','Catalysis of the reaction: urea = cyanamide + H(2)O.','2013-10-27','NSRP'),(11963,18822,'nitrile hydratase activity','F','Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.','2013-10-27','NSRP'),(11964,18823,'cyclohexa-1,5-dienecarbonyl-CoA hydratase activity','F','Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA.','2013-10-27','NSRP'),(11965,18824,'(hydroxyamino)benzene mutase activity','F','Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol.','2013-10-27','NSRP'),(11966,18825,'triethanolamine lyase activity','F','Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.','2013-10-27','NSRP'),(11967,18826,'methionine gamma-lyase activity','F','Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.','2013-10-27','NSRP'),(11968,18827,'1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity','F','Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.','2013-10-27','NSRP'),(11969,18828,'halohydrin hydrogen-halide-lyase A activity','F','Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.','2013-10-27','NSRP'),(11970,18829,'1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity','F','Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.','2013-10-27','NSRP'),(11971,18830,'gamma-hexachlorocyclohexane dehydrochlorinase activity','F','Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.','2013-10-27','NSRP'),(11972,18831,'5-chloro-1,2,4-trihydroxybenzene dechlorinase activity','F','Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.','2013-10-27','NSRP'),(11973,18832,'halohydrin hydrogen-halide-lyase B activity','F','Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.','2013-10-27','NSRP'),(11974,18833,'DDT-dehydrochlorinase activity','F','Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+).','2013-10-27','NSRP'),(11975,18834,'dichloromethane dehalogenase activity','F','Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+).','2013-10-27','NSRP'),(11976,18835,'carbon phosphorus lyase activity','F','Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).','2013-10-27','NSRP'),(11977,18836,'alkylmercury lyase activity','F','Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+.','2013-10-27','NSRP'),(11978,18837,'2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity','F','Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1\'-hydroxynaphth-2\'-yl)-2-oxobut-3-enoate.','2013-10-27','NSRP'),(11979,18838,'mandelate racemase activity','F','Catalysis of the reaction: (S)-mandelate = (R)-mandelate.','2013-10-27','NSRP'),(11980,18839,'cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity','F','Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.','2013-10-27','NSRP'),(11981,18842,'3-carboxymuconate cycloisomerase type II activity','F','Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone.','2013-10-27','NSRP'),(11982,18844,'2-hydroxytetrahydrofuran isomerase activity','F','Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde.','2013-10-27','NSRP'),(11983,18845,'2-hydroxychromene-2-carboxylate isomerase activity','F','Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.','2013-10-27','NSRP'),(11984,18846,'styrene-oxide isomerase activity','F','Catalysis of the reaction: styrene oxide = phenylacetaldehyde.','2013-10-27','NSRP'),(11985,18847,'alpha-pinene lyase activity','F','Catalysis of the reaction: alpha-pinene = limonene.','2013-10-27','NSRP'),(11986,18848,'pinocarveol isomerase activity','F','Catalysis of the reaction: pinocarveol = carveol.','2013-10-27','NSRP'),(11987,18849,'muconate cycloisomerase activity','F','Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.','2013-10-27','NSRP'),(11988,18850,'chloromuconate cycloisomerase activity','F','Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.','2013-10-27','NSRP'),(11989,18851,'alpha-pinene-oxide decyclase activity','F','Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.','2013-10-27','NSRP'),(11990,18852,'dichloromuconate cycloisomerase activity','F','Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.','2013-10-27','NSRP'),(11991,18853,'perillyl-CoA synthetase activity','F','OBSOLETE. Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + perillyl-CoA.','2013-10-27','NSRP'),(11992,18854,'3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity','F','Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.','2013-10-27','NSRP'),(11993,18855,'2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity','F','Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.','2013-10-27','NSRP'),(11994,18856,'benzoyl acetate-CoA ligase activity','F','Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.','2013-10-27','NSRP'),(11995,18857,'2,4-dichlorobenzoate-CoA ligase activity','F','Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.','2013-10-27','NSRP'),(11996,18858,'benzoate-CoA ligase activity','F','Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate + H(+).','2013-10-27','NSRP'),(11997,18859,'4-hydroxybenzoate-CoA ligase activity','F','Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.','2013-10-27','NSRP'),(11998,18860,'anthranilate-CoA ligase activity','F','Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.','2013-10-27','NSRP'),(11999,18861,'4-chlorobenzoate-CoA ligase activity','F','Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.','2013-10-27','NSRP'),(12000,18862,'phenylphosphate carboxylase activity','F','Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate.','2013-10-27','NSRP'),(12001,18863,'phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity','F','Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.','2013-10-27','NSRP'),(12002,18864,'acetylene metabolic process','P','The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.','2013-10-27','NSRP'),(12003,18865,'acrylonitrile metabolic process','P','The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.','2013-10-27','NSRP'),(12004,18866,'adamantanone metabolic process','P','The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.','2013-10-27','NSRP'),(12005,18867,'alpha-pinene metabolic process','P','The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.','2013-10-27','NSRP'),(12006,18868,'2-aminobenzenesulfonate metabolic process','P','The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.','2013-10-27','NSRP'),(12007,18870,'anaerobic 2-aminobenzoate metabolic process','P','The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.','2013-10-27','NSRP'),(12008,18871,'1-aminocyclopropane-1-carboxylate metabolic process','P','The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.','2013-10-27','NSRP'),