(29028,60378,'regulation of brood size','P','Any process that modulates the extent of brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.','2013-10-27','NSRP'),(29029,60379,'cardiac muscle cell myoblast differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.','2013-10-27','NSRP'),(29030,60380,'regulation of single-stranded telomeric DNA binding','P','Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.','2013-10-27','NSRP'),(29031,60381,'positive regulation of single-stranded telomeric DNA binding','P','Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.','2013-10-27','NSRP'),(29032,60382,'regulation of DNA strand elongation','P','Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3\' end of an existing DNA stand.','2013-10-27','NSRP'),(29033,60383,'positive regulation of DNA strand elongation','P','Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3\' end of an existing DNA stand.','2013-10-27','NSRP'),(29034,60384,'innervation','P','The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.','2013-10-27','NSRP'),(29035,60385,'axonogenesis involved in innervation','P','The neurite development process that generates a long process of a neuron, as it invades a target tissue.','2013-10-27','NSRP'),(29036,60386,'synapse assembly involved in innervation','P','The assembly of a synapse within a target tissue in which a nerve is invading.','2013-10-27','NSRP'),(29037,60387,'fertilization envelope','C','A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.','2013-10-27','NSRP'),(29038,60388,'vitelline envelope','C','A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.','2013-10-27','NSRP'),(29039,60389,'pathway-restricted SMAD protein phosphorylation','P','The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.','2013-10-27','NSRP'),(29040,60390,'regulation of SMAD protein import into nucleus','P','Any process that modulates the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(29041,60391,'positive regulation of SMAD protein import into nucleus','P','Any process that increases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(29042,60392,'negative regulation of SMAD protein import into nucleus','P','Any process that decreases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(29043,60393,'regulation of pathway-restricted SMAD protein phosphorylation','P','Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(29044,60394,'negative regulation of pathway-restricted SMAD protein phosphorylation','P','Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.','2013-10-27','NSRP'),(29045,60395,'SMAD protein signal transduction','P','The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.','2013-10-27','NSRP'),(29046,60396,'growth hormone receptor signaling pathway','P','The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.','2013-10-27','NSRP'),(29047,60397,'JAK-STAT cascade involved in growth hormone signaling pathway','P','The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.','2013-10-27','NSRP'),(29048,60398,'regulation of growth hormone receptor signaling pathway','P','Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.','2013-10-27','NSRP'),(29049,60399,'positive regulation of growth hormone receptor signaling pathway','P','Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.','2013-10-27','NSRP'),(29050,60400,'negative regulation of growth hormone receptor signaling pathway','P','Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.','2013-10-27','NSRP'),(29051,60401,'cytosolic calcium ion transport','P','The directed movement of calcium ions (Ca2+) into, out of or within the cytosol.','2013-10-27','NSRP'),(29052,60402,'calcium ion transport into cytosol','P','The directed movement of calcium ions (Ca2+) into the cytosol.','2013-10-27','NSRP'),(29053,60403,'post-mating oviposition','P','The deposition of eggs, either fertilized or not, upon a surface or into a medium, following mating.','2013-10-27','NSRP'),(29054,60404,'axonemal microtubule depolymerization','P','The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.','2013-10-27','NSRP'),(29055,60405,'regulation of penile erection','P','Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.','2013-10-27','NSRP'),(29056,60406,'positive regulation of penile erection','P','Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.','2013-10-27','NSRP'),(29057,60407,'negative regulation of penile erection','P','Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.','2013-10-27','NSRP'),(29058,60408,'regulation of acetylcholine metabolic process','P','Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.','2013-10-27','NSRP'),(29059,60409,'positive regulation of acetylcholine metabolic process','P','Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.','2013-10-27','NSRP'),(29060,60410,'negative regulation of acetylcholine metabolic process','P','Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.','2013-10-27','NSRP'),(29061,60411,'cardiac septum morphogenesis','P','The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.','2013-10-27','NSRP'),(29062,60412,'ventricular septum morphogenesis','P','The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.','2013-10-27','NSRP'),(29063,60413,'atrial septum morphogenesis','P','The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.','2013-10-27','NSRP'),(29064,60414,'aorta smooth muscle tissue morphogenesis','P','The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.','2013-10-27','NSRP'),(29065,60415,'muscle tissue morphogenesis','P','The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.','2013-10-27','NSRP'),(29066,60416,'response to growth hormone stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.','2013-10-27','NSRP'),(29067,60417,'yolk','C','The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.','2013-10-27','NSRP'),(29068,60418,'yolk plasma','C','Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.','2013-10-27','NSRP'),(29069,60419,'heart growth','P','The increase in size or mass of the heart.','2013-10-27','NSRP'),(29070,60420,'regulation of heart growth','P','Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.','2013-10-27','NSRP'),(29071,60421,'positive regulation of heart growth','P','Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.','2013-10-27','NSRP'),(29072,60422,'peptidyl-dipeptidase inhibitor activity','F','Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.','2013-10-27','NSRP'),(29073,60423,'foregut regionalization','P','The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.','2013-10-27','NSRP'),(29074,60424,'lung field specification','P','The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.','2013-10-27','NSRP'),(29075,60425,'lung morphogenesis','P','The process in which the anatomical structures of the lung are generated and organized.','2013-10-27','NSRP'),(29076,60426,'lung vasculature development','P','The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.','2013-10-27','NSRP'),(29077,60427,'lung connective tissue development','P','The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.','2013-10-27','NSRP'),(29078,60428,'lung epithelium development','P','The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.','2013-10-27','NSRP'),(29079,60429,'epithelium development','P','The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.','2013-10-27','NSRP'),(29080,60430,'lung saccule development','P','The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.','2013-10-27','NSRP'),(29081,60431,'primary lung bud formation','P','The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.','2013-10-27','NSRP'),(29082,60432,'lung pattern specification process','P','Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.','2013-10-27','NSRP'),(29083,60433,'bronchus development','P','The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.','2013-10-27','NSRP'),(29084,60434,'bronchus morphogenesis','P','The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.','2013-10-27','NSRP'),(29085,60435,'bronchiole development','P','The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.','2013-10-27','NSRP'),(29086,60436,'bronchiole morphogenesis','P','The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.','2013-10-27','NSRP'),(29087,60437,'lung growth','P','The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.','2013-10-27','NSRP'),(29088,60438,'trachea development','P','The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.','2013-10-27','NSRP'),(29089,60439,'trachea morphogenesis','P','The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.','2013-10-27','NSRP'),(29090,60440,'trachea formation','P','The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.','2013-10-27','NSRP'),(29091,60441,'epithelial tube branching involved in lung morphogenesis','P','The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.','2013-10-27','NSRP'),(29092,60442,'branching involved in prostate gland morphogenesis','P','The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.','2013-10-27','NSRP'),(29093,60443,'mammary gland morphogenesis','P','The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.','2013-10-27','NSRP'),(29094,60444,'branching involved in mammary gland duct morphogenesis','P','The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.','2013-10-27','NSRP'),(29095,60445,'branching involved in salivary gland morphogenesis','P','The process in which the branching structure of the salivary gland is generated and organized.','2013-10-27','NSRP'),(29096,60446,'branching involved in open tracheal system development','P','The process in which the anatomical structures of branches in the open tracheal system are generated and organized.','2013-10-27','NSRP'),(29097,60447,'bud outgrowth involved in lung branching','P','The process in which a region of the lung epithelium initiates an outgrowth.','2013-10-27','NSRP'),(29098,60448,'dichotomous subdivision of terminal units involved in lung branching','P','The process in which a lung bud bifurcates.','2013-10-27','NSRP'),(29099,60449,'bud elongation involved in lung branching','P','The process in which a bud in the lung grows out from the point where it is formed.','2013-10-27','NSRP'),(29100,60450,'positive regulation of hindgut contraction','P','Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.','2013-10-27','NSRP'),(29101,60451,'negative regulation of hindgut contraction','P','Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.','2013-10-27','NSRP'),(29102,60452,'positive regulation of cardiac muscle contraction','P','Any process that increases the frequency, rate or extent of cardiac muscle contraction.','2013-10-27','NSRP'),(29103,60453,'regulation of gastric acid secretion','P','Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.','2013-10-27','NSRP'),(29104,60454,'positive regulation of gastric acid secretion','P','Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.','2013-10-27','NSRP'),(29105,60455,'negative regulation of gastric acid secretion','P','Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.','2013-10-27','NSRP'),(29106,60456,'positive regulation of digestive system process','P','Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.','2013-10-27','NSRP'),(29107,60457,'negative regulation of digestive system process','P','Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.','2013-10-27','NSRP'),(29108,60458,'right lung development','P','The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.','2013-10-27','NSRP'),(29109,60459,'left lung development','P','The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.','2013-10-27','NSRP'),(29110,60460,'left lung morphogenesis','P','The process in which anatomical structures of the left lung are generated and organized.','2013-10-27','NSRP'),(29111,60461,'right lung morphogenesis','P','The process in which anatomical structures of the right lung are generated and organized.','2013-10-27','NSRP'),(29112,60462,'lung lobe development','P','The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.','2013-10-27','NSRP'),(29113,60463,'lung lobe morphogenesis','P','The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.','2013-10-27','NSRP'),(29114,60464,'lung lobe formation','P','The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.','2013-10-27','NSRP'),(29115,60465,'pharynx development','P','The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.','2013-10-27','NSRP'),(29116,60466,'activation of meiosis involved in egg activation','P','Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.','2013-10-27','NSRP'),(29117,60467,'negative regulation of fertilization','P','Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).','2013-10-27','NSRP'),(29118,60468,'prevention of polyspermy','P','The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.','2013-10-27','NSRP'),(29119,60469,'positive regulation of transcription involved in egg activation','P','Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation.','2013-10-27','NSRP'),(29120,60470,'elevation of cytosolic calcium ion concentration involved in egg activation','P','The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.','2013-10-27','NSRP'),(29121,60471,'cortical granule exocytosis','P','The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.','2013-10-27','NSRP'),(29122,60472,'positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration','P','Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.','2013-10-27','NSRP'),(29123,60473,'cortical granule','C','A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.','2013-10-27','NSRP'),(29124,60474,'positive regulation of sperm motility involved in capacitation','P','The process in which the controlled movement of a sperm cell is initiated as part of the process required for sperm to reach fertilization competence.','2013-10-27','NSRP'),(29125,60475,'positive regulation of actin filament polymerization involved in acrosome reaction','P','Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.','2013-10-27','NSRP'),(29126,60476,'protein localization involved in acrosome reaction','P','The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.','2013-10-27','NSRP'),(29127,60477,'peptidyl-serine phosphorylation involved in acrosome reaction','P','The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction.','2013-10-27','NSRP'),(29128,60478,'acrosomal vesicle exocytosis','P','The release of intracellular molecules contained within the acrosomal granule by fusion of the vesicle with the plasma membrane of the oocyte, requiring calcium ions.','2013-10-27','NSRP'),(29129,60479,'lung cell differentiation','P','The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.','2013-10-27','NSRP'),(29130,60480,'lung goblet cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.','2013-10-27','NSRP'),(29131,60481,'lobar bronchus epithelium development','P','The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.','2013-10-27','NSRP'),(29132,60482,'lobar bronchus development','P','The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.','2013-10-27','NSRP'),(29133,60483,'lobar bronchus mesenchyme development','P','The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.','2013-10-27','NSRP'),(29134,60484,'lung-associated mesenchyme development','P','The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.','2013-10-27','NSRP'),(29135,60485,'mesenchyme development','P','The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.','2013-10-27','NSRP'),(29136,60486,'Clara cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.','2013-10-27','NSRP'),(29137,60487,'lung epithelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.','2013-10-27','NSRP'),(29138,60488,'orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis','P','The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.','2013-10-27','NSRP'),(29139,60489,'planar dichotomous subdivision of terminal units involved in lung branching morphogenesis','P','The process in which a lung bud bifurcates parallel to the plane of the previous bud.','2013-10-27','NSRP'),(29140,60490,'lateral sprouting involved in lung morphogenesis','P','The process in which a branch forms along the side of the lung epithelial tube.','2013-10-27','NSRP'),(29141,60491,'regulation of cell projection assembly','P','Any process that modulates the rate, frequency, or extent of cell projection assembly.','2013-10-27','NSRP'),(29142,60492,'lung induction','P','The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.','2013-10-27','NSRP'),(29143,60493,'mesenchymal-endodermal cell signaling involved in lung induction','P','Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.','2013-10-27','NSRP'),(29144,60494,'inductive mesenchymal-endodermal cell signaling','P','Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.','2013-10-27','NSRP'),(29145,60495,'cell-cell signaling involved in lung development','P','Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.','2013-10-27','NSRP'),(29146,60496,'mesenchymal-epithelial cell signaling involved in lung development','P','Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.','2013-10-27','NSRP'),(29147,60497,'mesenchymal-endodermal cell signaling','P','Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.','2013-10-27','NSRP'),(29148,60498,'retinoic acid receptor signaling pathway involved in lung bud formation','P','The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.','2013-10-27','NSRP'),(29149,60499,'fibroblast growth factor receptor signaling pathway involved in lung induction','P','The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.','2013-10-27','NSRP'),(29150,60500,'regulation of transcription from RNA polymerase II promoter involved in lung bud formation','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed.','2013-10-27','NSRP'),(29151,60501,'positive regulation of epithelial cell proliferation involved in lung morphogenesis','P','Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.','2013-10-27','NSRP'),(29152,60502,'epithelial cell proliferation involved in lung morphogenesis','P','The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.','2013-10-27','NSRP'),(29153,60503,'bud dilation involved in lung branching','P','The process in which a bud in the lung increases radially.','2013-10-27','NSRP'),(29154,60504,'positive regulation of epithelial cell proliferation involved in lung bud dilation','P','Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.','2013-10-27','NSRP'),(29155,60505,'epithelial cell proliferation involved in lung bud dilation','P','The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.','2013-10-27','NSRP'),(29156,60506,'smoothened signaling pathway involved in lung development','P','The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.','2013-10-27','NSRP'),(29157,60507,'epidermal growth factor receptor signaling pathway involved in lung development','P','The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.','2013-10-27','NSRP'),(29158,60508,'lung basal cell differentiation','P','The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.','2013-10-27','NSRP'),(29159,60509,'Type I pneumocyte differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.','2013-10-27','NSRP'),(29160,60510,'Type II pneumocyte differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Type II pneumocyte. A Type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.','2013-10-27','NSRP'),(29161,60511,'creation of an inductive signal by a mesenchymal cell involved in lung induction','P','The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud.','2013-10-27','NSRP'),(29162,60512,'prostate gland morphogenesis','P','The process in which the anatomical structures of a prostate gland are generated and organized.','2013-10-27','NSRP'),(29163,60513,'prostatic bud formation','P','The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.','2013-10-27','NSRP'),(29164,60514,'prostate induction','P','The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.','2013-10-27','NSRP'),(29165,60515,'prostate field specification','P','The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.','2013-10-27','NSRP'),(29166,60516,'primary prostatic bud elongation','P','The increase in size of the prostatic bud as it forms.','2013-10-27','NSRP'),(29167,60517,'epithelial cell proliferation involved in prostatic bud elongation','P','The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.','2013-10-27','NSRP'),(29168,60518,'cell migration involved in prostatic bud elongation','P','The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.','2013-10-27','NSRP'),(29169,60519,'cell adhesion involved in prostatic bud elongation','P','The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.','2013-10-27','NSRP'),(29170,60520,'activation of prostate induction by androgen receptor signaling pathway','P','Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.','2013-10-27','NSRP'),(29171,60521,'mesenchymal-epithelial cell signaling involved in prostate induction','P','Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.','2013-10-27','NSRP'),(29172,60522,'inductive mesenchymal to epithelial cell signaling','P','Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.','2013-10-27','NSRP'),(29173,60523,'prostate epithelial cord elongation','P','The developmental growth process in which solid chords of prostate epithelium increase in length.','2013-10-27','NSRP'),(29174,60524,'dichotomous subdivision of prostate epithelial cord terminal unit','P','The process in which a prostate epithelial cord bifurcates at its end.','2013-10-27','NSRP'),(29175,60525,'prostate glandular acinus development','P','The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.','2013-10-27','NSRP'),(29176,60526,'prostate glandular acinus morphogenesis','P','The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.','2013-10-27','NSRP'),(29177,60527,'prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis','P','The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.','2013-10-27','NSRP'),(29178,60528,'secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development','P','The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.','2013-10-27','NSRP'),(29179,60529,'squamous basal epithelial stem cell differentiation involved in prostate gland acinus development','P','The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.','2013-10-27','NSRP'),(29180,60530,'smooth muscle cell differentiation involved in prostate glandular acinus development','P','The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.','2013-10-27','NSRP'),(29181,60531,'neuroendocrine cell differentiation involved in prostate gland acinus development','P','The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.','2013-10-27','NSRP'),(29182,60532,'bronchus cartilage development','P','The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(29183,60533,'bronchus cartilage morphogenesis','P','The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.','2013-10-27','NSRP'),(29184,60534,'trachea cartilage development','P','The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(29185,60535,'trachea cartilage morphogenesis','P','The process in which the anatomical structures of cartilage in the trachea are generated and organized.','2013-10-27','NSRP'),(29186,60536,'cartilage morphogenesis','P','The process in which the anatomical structures of cartilage are generated and organized.','2013-10-27','NSRP'),(29187,60537,'muscle tissue development','P','The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.','2013-10-27','NSRP'),(29188,60538,'skeletal muscle organ development','P','The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.','2013-10-27','NSRP'),(29189,60539,'diaphragm development','P','The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.','2013-10-27','NSRP'),(29190,60540,'diaphragm morphogenesis','P','The process in which the anatomical structures of the diaphragm are generated and organized.','2013-10-27','NSRP'),(29191,60541,'respiratory system development','P','The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.','2013-10-27','NSRP'),(29192,60542,'regulation of strand invasion','P','Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.','2013-10-27','NSRP'),(29193,60543,'negative regulation of strand invasion','P','Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.','2013-10-27','NSRP'),(29194,60544,'regulation of necroptosis','P','Any process that modulates the rate frequency or extent of necroptosis. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29195,60545,'positive regulation of necroptosis','P','Any process that increases the rate frequency or extent of necroptosis. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29196,60546,'negative regulation of necroptosis','P','Any process that decreases the rate frequency or extent of necroptosis. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29197,60547,'negative regulation of necrotic cell death','P','Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.','2013-10-27','NSRP'),(29198,60548,'negative regulation of cell death','P','Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.','2013-10-27','NSRP'),(29199,60549,'regulation of fructose 1,6-bisphosphate 1-phosphatase activity','P','Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.','2013-10-27','NSRP'),(29200,60550,'positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity','P','Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.','2013-10-27','NSRP'),(29201,60551,'regulation of fructose 1,6-bisphosphate metabolic process','P','Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.','2013-10-27','NSRP'),(29202,60552,'positive regulation of fructose 1,6-bisphosphate metabolic process','P','Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.','2013-10-27','NSRP'),(29203,60553,'activation of necroptosis','P','Any process that starts the inactive process of necroptosis. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29204,60554,'activation of necroptosis of activated-T cells','P','Any process that starts the inactive process of necroptosis in an activated T cell. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29205,60555,'activation of necroptosis by extracellular signals','P','Any process that starts the inactive process of necroptosis as a result of a signal outside the cell. Necroptosis is a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors and Toll-like receptors.','2013-10-27','NSRP'),(29206,60556,'regulation of vitamin D biosynthetic process','P','Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).','2013-10-27','NSRP'),(29207,60557,'positive regulation of vitamin D biosynthetic process','P','Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).','2013-10-27','NSRP'),(29208,60558,'regulation of calcidiol 1-monooxygenase activity','P','Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.','2013-10-27','NSRP'),(29209,60559,'positive regulation of calcidiol 1-monooxygenase activity','P','Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.','2013-10-27','NSRP'),(29210,60560,'developmental growth involved in morphogenesis','P','The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.','2013-10-27','NSRP'),(29211,60561,'apoptotic process involved in morphogenesis','P','Any apoptotic process that contributes to the shaping of an anatomical structure.','2013-10-27','NSRP'),(29212,60562,'epithelial tube morphogenesis','P','The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.','2013-10-27','NSRP'),(29213,60563,'neuroepithelial cell differentiation','P','The process in which epiblast cells acquire specialized features of neuroepithelial cells.','2013-10-27','NSRP'),(29214,60564,'negative regulation of mitotic anaphase-promoting complex activity','P','Any process that decreases the rate frequency or extent of anaphase-promoting complex activity regulating the mitotic cell cycle.','2013-10-27','NSRP'),(29215,60565,'inhibition of mitotic anaphase-promoting complex activity','P','Any process that prevents the activation of anaphase-promoting complex activity regulating the mitotic cell cycle.','2013-10-27','NSRP'),(29216,60566,'positive regulation of DNA-dependent transcription, termination','P','Any process that increases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.','2013-10-27','NSRP'),(29217,60567,'negative regulation of DNA-dependent transcription, termination','P','Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.','2013-10-27','NSRP'),(29218,60568,'regulation of peptide hormone processing','P','Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.','2013-10-27','NSRP'),(29219,60569,'positive regulation of peptide hormone processing','P','Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.','2013-10-27','NSRP'),(29220,60570,'negative regulation of peptide hormone processing','P','Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.','2013-10-27','NSRP'),(29221,60571,'morphogenesis of an epithelial fold','P','The morphogenetic process in which an epithelial sheet bends along a linear axis.','2013-10-27','NSRP'),(29222,60572,'morphogenesis of an epithelial bud','P','The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.','2013-10-27','NSRP'),(29223,60573,'cell fate specification involved in pattern specification','P','The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.','2013-10-27','NSRP'),(29224,60574,'intestinal epithelial cell maturation','P','The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.','2013-10-27','NSRP'),(29225,60575,'intestinal epithelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.','2013-10-27','NSRP'),(29226,60576,'intestinal epithelial cell development','P','The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29227,60577,'pulmonary vein morphogenesis','P','The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.','2013-10-27','NSRP'),(29228,60578,'superior vena cava morphogenesis','P','The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.','2013-10-27','NSRP'),(29229,60579,'ventral spinal cord interneuron fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.','2013-10-27','NSRP'),(29230,60580,'ventral spinal cord interneuron fate determination','P','The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.','2013-10-27','NSRP'),(29231,60581,'cell fate commitment involved in pattern specification','P','The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.','2013-10-27','NSRP'),(29232,60582,'cell fate determination involved in pattern specification','P','A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.','2013-10-27','NSRP'),(29233,60583,'regulation of actin cortical patch localization','P','Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.','2013-10-27','NSRP'),(29234,60584,'regulation of prostaglandin-endoperoxide synthase activity','P','Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.','2013-10-27','NSRP'),(29235,60585,'positive regulation of prostaglandin-endoperoxide synthase activity','P','Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.','2013-10-27','NSRP'),(29236,60586,'multicellular organismal iron ion homeostasis','P','Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.','2013-10-27','NSRP'),(29237,60587,'regulation of lipoprotein lipid oxidation','P','Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.','2013-10-27','NSRP'),(29238,60588,'negative regulation of lipoprotein lipid oxidation','P','Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.','2013-10-27','NSRP'),(29239,60589,'nucleoside-triphosphatase regulator activity','F','Modulates the rate of NTP hydrolysis by a NTPase.','2013-10-27','NSRP'),(29240,60590,'ATPase regulator activity','F','Modulates the rate of ATP hydrolysis by an ATPase.','2013-10-27','NSRP'),(29241,60591,'chondroblast differentiation','P','The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.','2013-10-27','NSRP'),(29242,60592,'mammary gland formation','P','The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.','2013-10-27','NSRP'),(29243,60593,'Wnt receptor signaling pathway involved in mammary gland specification','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.','2013-10-27','NSRP'),(29244,60594,'mammary gland specification','P','The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.','2013-10-27','NSRP'),(29245,60595,'fibroblast growth factor receptor signaling pathway involved in mammary gland specification','P','The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.','2013-10-27','NSRP'),(29246,60596,'mammary placode formation','P','The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.','2013-10-27','NSRP'),(29247,60597,'regulation of transcription from RNA polymerase II promoter involved in mammary gland formation','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud.','2013-10-27','NSRP'),(29248,60598,'dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis','P','The process in which the terminal end of a mammary duct bifurcates.','2013-10-27','NSRP'),(29249,60599,'lateral sprouting involved in mammary gland duct morphogenesis','P','The process in which a branch forms along the side of a mammary duct.','2013-10-27','NSRP'),(29250,60600,'dichotomous subdivision of an epithelial terminal unit','P','The process in which an epithelial cord, rod or tube bifurcates at its end.','2013-10-27','NSRP'),(29251,60601,'lateral sprouting from an epithelium','P','The process in which a branch forms along the side of an epithelium.','2013-10-27','NSRP'),(29252,60602,'branch elongation of an epithelium','P','The growth process in which a branch increases in length from its base to its tip.','2013-10-27','NSRP'),(29253,60603,'mammary gland duct morphogenesis','P','The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.','2013-10-27','NSRP'),(29254,60604,'mammary gland duct cavitation','P','Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.','2013-10-27','NSRP'),(29255,60605,'tube lumen cavitation','P','The formation of a lumen by hollowing out a solid rod or cord.','2013-10-27','NSRP'),(29256,60606,'tube closure','P','Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.','2013-10-27','NSRP'),(29257,60607,'cell-cell adhesion involved in sealing an epithelial fold','P','The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.','2013-10-27','NSRP'),(29258,60608,'cell-cell adhesion involved in neural tube closure','P','The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.','2013-10-27','NSRP'),(29259,60609,'apoptotic process involved in tube lumen cavitation','P','Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.','2013-10-27','NSRP'),(29260,60610,'mesenchymal cell differentiation involved in mammary gland development','P','The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.','2013-10-27','NSRP'),(29261,60611,'mammary gland fat development','P','The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.','2013-10-27','NSRP'),(29262,60612,'adipose tissue development','P','The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.','2013-10-27','NSRP'),(29263,60613,'fat pad development','P','The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.','2013-10-27','NSRP'),(29264,60614,'negative regulation of mammary gland development in males by androgen receptor signaling pathway','P','Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.','2013-10-27','NSRP'),(29265,60615,'mammary gland bud formation','P','The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.','2013-10-27','NSRP'),(29266,60616,'mammary gland cord formation','P','The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.','2013-10-27','NSRP'),(29267,60617,'positive regulation of mammary placode formation by mesenchymal-epithelial signaling','P','Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.','2013-10-27','NSRP'),(29268,60618,'nipple development','P','The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.','2013-10-27','NSRP'),(29269,60619,'cell migration involved in mammary placode formation','P','The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.','2013-10-27','NSRP'),(29270,60620,'regulation of cholesterol import','P','Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.','2013-10-27','NSRP'),(29271,60621,'negative regulation of cholesterol import','P','Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.','2013-10-27','NSRP'),(29272,60622,'regulation of ascospore wall beta-glucan biosynthetic process','P','Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.','2013-10-27','NSRP'),(29273,60623,'regulation of chromosome condensation','P','Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.','2013-10-27','NSRP'),(29274,60624,'regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process','P','Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.','2013-10-27','NSRP'),(29275,60625,'regulation of protein deneddylation','P','Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.','2013-10-27','NSRP'),(29276,60626,'regulation of cullin deneddylation','P','Any process that modulates the rate, frequency or extent of cullin deneddylation, the modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1).','2013-10-27','NSRP'),(29277,60627,'regulation of vesicle-mediated transport','P','Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.','2013-10-27','NSRP'),(29278,60628,'regulation of ER to Golgi vesicle-mediated transport','P','Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.','2013-10-27','NSRP'),(29279,60629,'regulation of homologous chromosome segregation','P','Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.','2013-10-27','NSRP'),(29280,60630,'regulation of M/G1 transition of mitotic cell cycle','P','OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle.','2013-10-27','NSRP'),(29281,60631,'regulation of meiosis I','P','Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.','2013-10-27','NSRP'),(29282,60632,'regulation of microtubule-based movement','P','Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.','2013-10-27','NSRP'),(29283,60633,'negative regulation of transcription initiation from RNA polymerase II promoter','P','Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.','2013-10-27','NSRP'),(29284,60634,'regulation of 4,6-pyruvylated galactose residue biosynthetic process','P','Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.','2013-10-27','NSRP'),(29285,60635,'positive regulation of (1->3)-beta-D-glucan biosynthetic process','P','Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.','2013-10-27','NSRP'),(29286,60636,'negative regulation of (1->3)-beta-D-glucan biosynthetic process','P','Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.','2013-10-27','NSRP'),(29287,60637,'positive regulation of lactation by mesenchymal-epithelial cell signaling','P','The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.','2013-10-27','NSRP'),(29288,60638,'mesenchymal-epithelial cell signaling','P','Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.','2013-10-27','NSRP'),(29289,60639,'positive regulation of salivary gland formation by mesenchymal-epithelial signaling','P','Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.','2013-10-27','NSRP'),(29290,60640,'positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling','P','Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.','2013-10-27','NSRP'),(29291,60641,'mammary gland duct regression in males','P','The process in which the epithelium of the mammary duct is destroyed in males.','2013-10-27','NSRP'),(29292,60642,'white fat cell differentiation involved in mammary gland fat development','P','The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.','2013-10-27','NSRP'),(29293,60643,'epithelial cell differentiation involved in mammary gland bud morphogenesis','P','The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.','2013-10-27','NSRP'),(29294,60644,'mammary gland epithelial cell differentiation','P','The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.','2013-10-27','NSRP'),(29295,60645,'peripheral mammary gland bud epithelial cell differentiation','P','The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.','2013-10-27','NSRP'),(29296,60646,'internal mammary gland bud epithelial cell differentiation','P','The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.','2013-10-27','NSRP'),(29297,60647,'mesenchymal cell condensation involved in mammary fat development','P','The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.','2013-10-27','NSRP'),(29298,60648,'mammary gland bud morphogenesis','P','The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.','2013-10-27','NSRP'),(29299,60649,'mammary gland bud elongation','P','The process in which the mammary gland bud grows along its axis.','2013-10-27','NSRP'),(29300,60650,'epithelial cell proliferation involved in mammary gland bud elongation','P','The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.','2013-10-27','NSRP'),(29301,60651,'regulation of epithelial cell proliferation involved in mammary gland bud elongation','P','Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.','2013-10-27','NSRP'),(29302,60652,'mammary gland cord morphogenesis','P','The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.','2013-10-27','NSRP'),(29303,60653,'epithelial cell differentiation involved in mammary gland cord morphogenesis','P','The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.','2013-10-27','NSRP'),(29304,60654,'mammary gland cord elongation','P','The process in which the mammary gland sprout grows along its axis.','2013-10-27','NSRP'),(29305,60655,'branching involved in mammary gland cord morphogenesis','P','The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.','2013-10-27','NSRP'),(29306,60656,'regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling','P','Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.','2013-10-27','NSRP'),(29307,60657,'regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling','P','Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.','2013-10-27','NSRP'),(29308,60658,'nipple morphogenesis','P','The process in which the nipple is generated and organized.','2013-10-27','NSRP'),(29309,60659,'nipple sheath formation','P','The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.','2013-10-27','NSRP'),(29310,60660,'epidermis morphogenesis involved in nipple formation','P','The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.','2013-10-27','NSRP'),(29311,60661,'submandibular salivary gland formation','P','The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.','2013-10-27','NSRP'),(29312,60662,'salivary gland cavitation','P','The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.','2013-10-27','NSRP'),(29313,60663,'apoptotic process involved in salivary gland cavitation','P','Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.','2013-10-27','NSRP'),(29314,60664,'epithelial cell proliferation involved in salivary gland morphogenesis','P','The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.','2013-10-27','NSRP'),(29315,60665,'regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling','P','Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.','2013-10-27','NSRP'),(29316,60666,'dichotomous subdivision of terminal units involved in salivary gland branching','P','The process in which a salivary epithelial cord bifurcates at its end.','2013-10-27','NSRP'),(29317,60667,'branch elongation involved in salivary gland morphogenesis','P','The differential growth of the salivary branches along their axis, resulting in the growth of a branch.','2013-10-27','NSRP'),(29318,60668,'regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling','P','Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.','2013-10-27','NSRP'),(29319,60669,'embryonic placenta morphogenesis','P','The process in which the embryonic placenta is generated and organized.','2013-10-27','NSRP'),(29320,60670,'branching involved in labyrinthine layer morphogenesis','P','The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.','2013-10-27','NSRP'),(29321,60671,'epithelial cell differentiation involved in embryonic placenta development','P','The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.','2013-10-27','NSRP'),(29322,60672,'epithelial cell morphogenesis involved in placental branching','P','The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.','2013-10-27','NSRP'),(29323,60673,'cell-cell signaling involved in placenta development','P','Any process that mediates the transfer of information from one cell to another.','2013-10-27','NSRP'),(29324,60674,'placenta blood vessel development','P','The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29325,60675,'ureteric bud morphogenesis','P','The process in which the ureteric bud is generated and organized.','2013-10-27','NSRP'),(29326,60676,'ureteric bud formation','P','The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.','2013-10-27','NSRP'),(29327,60677,'ureteric bud elongation','P','The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.','2013-10-27','NSRP'),(29328,60678,'dichotomous subdivision of terminal units involved in ureteric bud branching','P','The process in which a ureteric bud bifurcates at its end.','2013-10-27','NSRP'),(29329,60679,'trifid subdivision of terminal units involved in ureteric bud branching','P','The process in which a ureteric bud splits into three units at its end.','2013-10-27','NSRP'),(29330,60680,'lateral sprouting involved in ureteric bud morphogenesis','P','The process in which a branch forms along the side of a ureteric bud.','2013-10-27','NSRP'),(29331,60681,'branch elongation involved in ureteric bud branching','P','The growth of a branch of the ureteric bud along its axis.','2013-10-27','NSRP'),(29332,60682,'primary ureteric bud growth','P','The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.','2013-10-27','NSRP'),(29333,60683,'regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling','P','Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.','2013-10-27','NSRP'),(29334,60684,'epithelial-mesenchymal cell signaling','P','Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.','2013-10-27','NSRP'),(29335,60685,'regulation of prostatic bud formation','P','Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.','2013-10-27','NSRP'),(29336,60686,'negative regulation of prostatic bud formation','P','Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.','2013-10-27','NSRP'),(29337,60687,'regulation of branching involved in prostate gland morphogenesis','P','Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.','2013-10-27','NSRP'),(29338,60688,'regulation of morphogenesis of a branching structure','P','Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.','2013-10-27','NSRP'),(29339,60689,'cell differentiation involved in salivary gland development','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.','2013-10-27','NSRP'),(29340,60690,'epithelial cell differentiation involved in salivary gland development','P','The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.','2013-10-27','NSRP'),(29341,60691,'epithelial cell maturation involved in salivary gland development','P','The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.','2013-10-27','NSRP'),(29342,60692,'mesenchymal cell differentiation involved in salivary gland development','P','The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.','2013-10-27','NSRP'),(29343,60693,'regulation of branching involved in salivary gland morphogenesis','P','Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.','2013-10-27','NSRP'),(29344,60694,'regulation of cholesterol transporter activity','P','Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.','2013-10-27','NSRP'),(29345,60695,'negative regulation of cholesterol transporter activity','P','Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.','2013-10-27','NSRP'),(29346,60696,'regulation of phospholipid catabolic process','P','Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.','2013-10-27','NSRP'),(29347,60697,'positive regulation of phospholipid catabolic process','P','Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.','2013-10-27','NSRP'),(29348,60698,'endoribonuclease inhibitor activity','F','Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.','2013-10-27','NSRP'),(29349,60699,'regulation of endoribonuclease activity','P','Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.','2013-10-27','NSRP'),(29350,60700,'regulation of ribonuclease activity','P','Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.','2013-10-27','NSRP'),(29351,60701,'negative regulation of ribonuclease activity','P','Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.','2013-10-27','NSRP'),(29352,60702,'negative regulation of endoribonuclease activity','P','Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.','2013-10-27','NSRP'),(29353,60703,'deoxyribonuclease inhibitor activity','F','Stops, prevents or reduces the activity of deoxyribonuclease.','2013-10-27','NSRP'),(29354,60704,'acinar cell differentiation involved in salivary gland development','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.','2013-10-27','NSRP'),(29355,60705,'neuron differentiation involved in salivary gland development','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.','2013-10-27','NSRP'),(29356,60706,'cell differentiation involved in embryonic placenta development','P','The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.','2013-10-27','NSRP'),(29357,60707,'trophoblast giant cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.','2013-10-27','NSRP'),(29358,60708,'spongiotrophoblast differentiation','P','The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.','2013-10-27','NSRP'),(29359,60709,'glycogen cell differentiation involved in embryonic placenta development','P','The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.','2013-10-27','NSRP'),(29360,60710,'chorio-allantoic fusion','P','The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.','2013-10-27','NSRP'),(29361,60711,'labyrinthine layer development','P','The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.','2013-10-27','NSRP'),(29362,60712,'spongiotrophoblast layer development','P','The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.','2013-10-27','NSRP'),(29363,60713,'labyrinthine layer morphogenesis','P','The process in which the labyrinthine layer of the placenta is generated and organized.','2013-10-27','NSRP'),(29364,60714,'labyrinthine layer formation','P','The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.','2013-10-27','NSRP'),(29365,60715,'syncytiotrophoblast cell differentiation involved in labyrinthine layer development','P','The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.','2013-10-27','NSRP'),(29366,60716,'labyrinthine layer blood vessel development','P','The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.','2013-10-27','NSRP'),(29367,60717,'chorion development','P','The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.','2013-10-27','NSRP'),(29368,60718,'chorionic trophoblast cell differentiation','P','The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.','2013-10-27','NSRP'),(29369,60719,'chorionic trophoblast cell development','P','The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.','2013-10-27','NSRP'),(29370,60720,'spongiotrophoblast cell proliferation','P','The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.','2013-10-27','NSRP'),(29371,60721,'regulation of spongiotrophoblast cell proliferation','P','Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.','2013-10-27','NSRP'),(29372,60722,'cell proliferation involved in embryonic placenta development','P','The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.','2013-10-27','NSRP'),(29373,60723,'regulation of cell proliferation involved in embryonic placenta development','P','Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.','2013-10-27','NSRP'),(29374,60724,'coreceptor activity involved in epidermal growth factor receptor signaling pathway','F','Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway.','2013-10-27','NSRP'),(29375,60725,'regulation of coreceptor activity','P','Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.','2013-10-27','NSRP'),(29376,60726,'regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway','P','Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.','2013-10-27','NSRP'),(29377,60727,'positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway','P','Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.','2013-10-27','NSRP'),(29378,60728,'negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway','P','Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.','2013-10-27','NSRP'),(29379,60729,'intestinal epithelial structure maintenance','P','A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.','2013-10-27','NSRP'),(29380,60730,'regulation of intestinal epithelial structure maintenance','P','Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.','2013-10-27','NSRP'),(29381,60731,'positive regulation of intestinal epithelial structure maintenance','P','Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.','2013-10-27','NSRP'),(29382,60732,'positive regulation of inositol phosphate biosynthetic process','P','Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.','2013-10-27','NSRP'),(29383,60733,'regulation of eIF2 alpha phosphorylation by amino acid starvation','P','Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation.','2013-10-27','NSRP'),(29384,60734,'regulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress','P','Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.','2013-10-27','NSRP'),(29385,60735,'regulation of eIF2 alpha phosphorylation by dsRNA','P','Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.','2013-10-27','NSRP'),(29386,60736,'prostate gland growth','P','The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.','2013-10-27','NSRP'),(29387,60737,'prostate gland morphogenetic growth','P','The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.','2013-10-27','NSRP'),(29388,60738,'epithelial-mesenchymal signaling involved in prostate gland development','P','Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29389,60739,'mesenchymal-epithelial cell signaling involved in prostate gland development','P','Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29390,60740,'prostate gland epithelium morphogenesis','P','The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.','2013-10-27','NSRP'),(29391,60741,'prostate gland stromal morphogenesis','P','The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.','2013-10-27','NSRP'),(29392,60742,'epithelial cell differentiation involved in prostate gland development','P','The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.','2013-10-27','NSRP'),(29393,60743,'epithelial cell maturation involved in prostate gland development','P','The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.','2013-10-27','NSRP'),(29394,60744,'mammary gland branching involved in thelarche','P','The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.','2013-10-27','NSRP'),(29395,60745,'mammary gland branching involved in pregnancy','P','The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.','2013-10-27','NSRP'),(29396,60746,'parental behavior','P','A reproductive behavior in which a parent cares for and rears offspring.','2013-10-27','NSRP'),(29397,60747,'oral incubation','P','A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.','2013-10-27','NSRP'),(29398,60748,'tertiary branching involved in mammary gland duct morphogenesis','P','The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.','2013-10-27','NSRP'),(29399,60749,'mammary gland alveolus development','P','The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.','2013-10-27','NSRP'),(29400,60750,'epithelial cell proliferation involved in mammary gland duct elongation','P','The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.','2013-10-27','NSRP'),(29401,60751,'branch elongation involved in mammary gland duct branching','P','The developmental growth process in which a branch of a mammary gland duct elongates.','2013-10-27','NSRP'),(29402,60752,'intestinal phytosterol absorption','P','Any process in which phytosterols are taken up from the contents of the intestine.','2013-10-27','NSRP'),(29403,60753,'regulation of mast cell chemotaxis','P','Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.','2013-10-27','NSRP'),(29404,60754,'positive regulation of mast cell chemotaxis','P','Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.','2013-10-27','NSRP'),(29405,60755,'negative regulation of mast cell chemotaxis','P','Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.','2013-10-27','NSRP'),(29406,60756,'foraging behavior','P','Behavior by which an organism locates food.','2013-10-27','NSRP'),(29407,60757,'adult foraging behavior','P','Behavior by which an adult locates food.','2013-10-27','NSRP'),(29408,60758,'foraging behavior by probing substrate','P','Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.','2013-10-27','NSRP'),(29409,60759,'regulation of response to cytokine stimulus','P','Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.','2013-10-27','NSRP'),(29410,60760,'positive regulation of response to cytokine stimulus','P','Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.','2013-10-27','NSRP'),(29411,60761,'negative regulation of response to cytokine stimulus','P','Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.','2013-10-27','NSRP'),(29412,60762,'regulation of branching involved in mammary gland duct morphogenesis','P','Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.','2013-10-27','NSRP'),(29413,60763,'mammary duct terminal end bud growth','P','The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.','2013-10-27','NSRP'),(29414,60764,'cell-cell signaling involved in mammary gland development','P','Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.','2013-10-27','NSRP'),(29415,60765,'regulation of androgen receptor signaling pathway','P','Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.','2013-10-27','NSRP'),(29416,60766,'negative regulation of androgen receptor signaling pathway','P','Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.','2013-10-27','NSRP'),(29417,60767,'epithelial cell proliferation involved in prostate gland development','P','The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29418,60768,'regulation of epithelial cell proliferation involved in prostate gland development','P','Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29419,60769,'positive regulation of epithelial cell proliferation involved in prostate gland development','P','Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29420,60770,'negative regulation of epithelial cell proliferation involved in prostate gland development','P','Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29421,60771,'phyllotactic patterning','P','The radial pattern formation process that results in the formation of leaf or flower primordia around the center of a shoot apical meristem.','2013-10-27','NSRP'),(29422,60772,'leaf phyllotactic patterning','P','The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.','2013-10-27','NSRP'),(29423,60773,'flower phyllotactic patterning','P','The radial pattern formation process that results in the formation of flower primordia around the center of a shoot apical meristem.','2013-10-27','NSRP'),(29424,60774,'auxin mediated signaling pathway involved in phyllotactic patterning','P','The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.','2013-10-27','NSRP'),(29425,60775,'planar cell polarity pathway involved in gastrula mediolateral intercalation','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.','2013-10-27','NSRP'),(29426,60776,'simple leaf morphogenesis','P','The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.','2013-10-27','NSRP'),(29427,60777,'compound leaf morphogenesis','P','The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.','2013-10-27','NSRP'),(29428,60778,'primary leaflet morphogenesis','P','The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.','2013-10-27','NSRP'),(29429,60779,'secondary leaflet morphogenesis','P','The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.','2013-10-27','NSRP'),(29430,60780,'intercalary leaflet morphogenesis','P','The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.','2013-10-27','NSRP'),(29431,60781,'mesenchymal cell proliferation involved in prostate gland development','P','The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.','2013-10-27','NSRP'),(29432,60782,'regulation of mesenchymal cell proliferation involved in prostate gland development','P','Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.','2013-10-27','NSRP'),(29433,60783,'mesenchymal smoothened signaling pathway involved in prostate gland development','P','The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.','2013-10-27','NSRP'),(29434,60784,'regulation of cell proliferation involved in tissue homeostasis','P','Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.','2013-10-27','NSRP'),(29435,60785,'regulation of apoptosis involved in tissue homeostasis','P','Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.','2013-10-27','NSRP'),(29436,60786,'regulation of cell differentiation involved in tissue homeostasis','P','Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.','2013-10-27','NSRP'),(29437,60787,'positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway','P','Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.','2013-10-27','NSRP'),(29438,60788,'ectodermal placode formation','P','The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.','2013-10-27','NSRP'),(29439,60789,'hair follicle placode formation','P','The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.','2013-10-27','NSRP'),(29440,60790,'tooth placode formation','P','The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.','2013-10-27','NSRP'),(29441,60791,'sebaceous gland placode formation','P','The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.','2013-10-27','NSRP'),(29442,60792,'sweat gland development','P','The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.','2013-10-27','NSRP'),(29443,60793,'sweat gland placode formation','P','The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.','2013-10-27','NSRP'),(29444,60794,'leaflet morphogenesis','P','The process in which the anatomical structures of the leaflet are generated and organized.','2013-10-27','NSRP'),(29445,60795,'cell fate commitment involved in formation of primary germ layer','P','The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.','2013-10-27','NSRP'),(29446,60796,'regulation of transcription involved in primary germ layer cell fate commitment','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate.','2013-10-27','NSRP'),(29447,60797,'transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment','P','A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.','2013-10-27','NSRP'),(29448,60798,'transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification','P','The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate.','2013-10-27','NSRP'),(29449,60799,'transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification','P','The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.','2013-10-27','NSRP'),(29450,60800,'regulation of cell differentiation involved in embryonic placenta development','P','Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.','2013-10-27','NSRP'),(29451,60801,'negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway','P','The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast.','2013-10-27','NSRP'),(29452,60802,'epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification','P','Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.','2013-10-27','NSRP'),(29453,60803,'BMP signaling pathway involved in mesodermal cell fate specification','P','A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate.','2013-10-27','NSRP'),(29454,60804,'positive regulation of Wnt receptor signaling pathway by BMP signaling pathway','P','A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt receptor signaling pathway.','2013-10-27','NSRP'),(29455,60805,'negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter','P','Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast.','2013-10-27','NSRP'),(29456,60806,'negative regulation of cell differentiation involved in embryonic placenta development','P','Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.','2013-10-27','NSRP'),(29457,60807,'regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.','2013-10-27','NSRP'),(29458,60808,'positive regulation of mesodermal to mesenchymal transition involved in gastrulation','P','Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.','2013-10-27','NSRP'),(29459,60809,'mesodermal to mesenchymal transition involved in gastrulation','P','The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.','2013-10-27','NSRP'),(29460,60810,'intracellular mRNA localization involved in pattern specification process','P','Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.','2013-10-27','NSRP'),(29461,60811,'intracellular mRNA localization involved in anterior/posterior axis specification','P','Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.','2013-10-27','NSRP'),(29462,60812,'orthodenticle mRNA localization','P','Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.','2013-10-27','NSRP'),(29463,60813,'anterior mRNA localization involved in anterior/posterior axis specification','P','Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.','2013-10-27','NSRP'),(29464,60814,'posterior mRNA localization involved in anterior/posterior axis specification','P','Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.','2013-10-27','NSRP'),(29465,60815,'regulation of translation involved in anterior/posterior axis specification','P','Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.','2013-10-27','NSRP'),(29466,60816,'random inactivation of X chromosome','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.','2013-10-27','NSRP'),(29467,60817,'inactivation of paternal X chromosome','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.','2013-10-27','NSRP'),(29468,60818,'inactivation of paternal X chromosome by genetic imprinting','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting.','2013-10-27','NSRP'),(29469,60819,'inactivation of X chromosome by genetic imprinting','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting.','2013-10-27','NSRP'),(29470,60820,'inactivation of X chromosome by heterochromatin assembly','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.','2013-10-27','NSRP'),(29471,60821,'inactivation of X chromosome by DNA methylation','P','Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation.','2013-10-27','NSRP'),(29472,60822,'transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification','P','The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate.','2013-10-27','NSRP'),(29473,60823,'canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.','2013-10-27','NSRP'),(29474,60824,'retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.','2013-10-27','NSRP'),(29475,60825,'fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.','2013-10-27','NSRP'),(29476,60826,'transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern.','2013-10-27','NSRP'),(29477,60827,'regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','Any process that modulates the rate, frequency, or extent of Wnt receptor signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.','2013-10-27','NSRP'),(29478,60828,'regulation of canonical Wnt receptor signaling pathway','P','Any process that modulates the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.','2013-10-27','NSRP'),(29479,60829,'negative regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation','P','Any process that decreases the rate, frequency, or extent of the Wnt receptor signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.','2013-10-27','NSRP'),(29480,60830,'ciliary receptor clustering involved in smoothened signaling pathway','P','Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.','2013-10-27','NSRP'),(29481,60831,'smoothened signaling pathway involved in dorsal/ventral neural tube patterning','P','The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.','2013-10-27','NSRP'),(29482,60832,'oocyte animal/vegetal axis specification','P','The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.','2013-10-27','NSRP'),(29483,60833,'Wnt receptor signaling pathway involved in animal/vegetal axis specification','P','The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.','2013-10-27','NSRP'),(29484,60834,'oral/aboral axis specification','P','The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.','2013-10-27','NSRP'),(29485,60835,'transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification','P','A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis.','2013-10-27','NSRP'),(29486,60836,'lymphatic endothelial cell differentiation','P','The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.','2013-10-27','NSRP'),(29487,60837,'blood vessel endothelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.','2013-10-27','NSRP'),(29488,60838,'lymphatic endothelial cell fate commitment','P','The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.','2013-10-27','NSRP'),(29489,60839,'endothelial cell fate commitment','P','The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.','2013-10-27','NSRP'),(29490,60840,'artery development','P','The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.','2013-10-27','NSRP'),(29491,60841,'venous blood vessel development','P','The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.','2013-10-27','NSRP'),(29492,60842,'arterial endothelial cell differentiation','P','The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.','2013-10-27','NSRP'),(29493,60843,'venous endothelial cell differentiation','P','The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.','2013-10-27','NSRP'),(29494,60844,'arterial endothelial cell fate commitment','P','The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.','2013-10-27','NSRP'),(29495,60845,'venous endothelial cell fate commitment','P','The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.','2013-10-27','NSRP'),(29496,60846,'blood vessel endothelial cell fate commitment','P','The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.','2013-10-27','NSRP'),(29497,60847,'endothelial cell fate specification','P','The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.','2013-10-27','NSRP'),(29498,60848,'endothelial cell fate determination','P','A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.','2013-10-27','NSRP'),(29499,60849,'regulation of transcription involved in lymphatic endothelial cell fate commitment','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.','2013-10-27','NSRP'),(29500,60850,'regulation of transcription involved in cell fate commitment','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.','2013-10-27','NSRP'),(29501,60851,'vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment','P','The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.','2013-10-27','NSRP'),(29502,60852,'regulation of transcription involved in venous endothelial cell fate commitment','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate.','2013-10-27','NSRP'),(29503,60853,'Notch signaling pathway involved in arterial endothelial cell fate commitment','P','The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.','2013-10-27','NSRP'),(29504,60854,'patterning of lymph vessels','P','The process that regulates the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.','2013-10-27','NSRP'),(29505,60855,'venous endothelial cell migration involved in lymph vessel development','P','The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.','2013-10-27','NSRP'),(29506,60856,'establishment of blood-brain barrier','P','Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.','2013-10-27','NSRP'),(29507,60857,'establishment of glial blood-brain barrier','P','Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.','2013-10-27','NSRP'),(29508,60858,'vesicle-mediated transport involved in floral organ abscission','P','The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.','2013-10-27','NSRP'),(29509,60859,'regulation of vesicle-mediated transport involved in floral organ abscission','P','Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.','2013-10-27','NSRP'),(29510,60860,'regulation of floral organ abscission','P','Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.','2013-10-27','NSRP'),(29511,60861,'positive regulation of floral organ abscission','P','Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.','2013-10-27','NSRP'),(29512,60862,'negative regulation of floral organ abscission','P','Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.','2013-10-27','NSRP');
INSERT INTO `GO` VALUES (29513,60863,'regulation of floral organ abscission by signal transduction','P','The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.','2013-10-27','NSRP'),(29514,60864,'positive regulation of floral organ abscission by small GTPase mediated signal transduction','P','Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission.','2013-10-27','NSRP'),(29515,60865,'negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway','P','The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.','2013-10-27','NSRP'),(29516,60866,'leaf abscission','P','The controlled shedding of a leaf.','2013-10-27','NSRP'),(29517,60867,'fruit abscission','P','The controlled shedding of a fruit.','2013-10-27','NSRP'),(29518,60868,'regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction','P','Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission.','2013-10-27','NSRP'),(29519,60869,'transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission','P','A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.','2013-10-27','NSRP'),(29520,60870,'cell wall disassembly involved in floral organ abscission','P','A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.','2013-10-27','NSRP'),(29521,60871,'cellular cell wall disassembly','P','A cellular process that results in the breakdown of the cell wall.','2012-03-14','NSRP'),(29522,60872,'semicircular canal development','P','The progression of the semicircular canal from its initial formation to the mature structure.','2013-10-27','NSRP'),(29523,60873,'anterior semicircular canal development','P','The progession of the anterior semicircular canal from its initial formation to the mature structure.','2013-10-27','NSRP'),(29524,60874,'posterior semicircular canal development','P','The progession of the posterior semicircular canal from its initial formation to the mature structure.','2013-10-27','NSRP'),(29525,60875,'lateral semicircular canal development','P','The progession of the lateral semicircular canal from its initial formation to the mature structure.','2013-10-27','NSRP'),(29526,60876,'semicircular canal formation','P','The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.','2013-10-27','NSRP'),(29527,60877,'regionalization involved in semicircular canal formation','P','The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.','2013-10-27','NSRP'),(29528,60878,'pouch outgrowth involved in semicircular canal formation','P','The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.','2013-10-27','NSRP'),(29529,60879,'semicircular canal fusion','P','Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms ruing the process of semicircular canal formation.','2013-10-27','NSRP'),(29530,60880,'cell morphogenesis involved in semicircular canal fusion','P','The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.','2013-10-27','NSRP'),(29531,60881,'basal lamina disassembly','P','A process that results in the breakdown of the basal lamina.','2013-10-27','NSRP'),(29532,60882,'basal lamina disassembly involved in semicircular canal fusion','P','A process that results in the breakdown of the basal lamina that contributes to the process of semicircular canal fusion.','2013-10-27','NSRP'),(29533,60883,'regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication','P','Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basal lamina disassembly involved in semicircular canal fusion.','2013-10-27','NSRP'),(29534,60884,'clearance of cells from fusion plate','P','The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.','2013-10-27','NSRP'),(29535,60885,'clearance of cells from fusion plate by apoptotic process','P','Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.','2013-10-27','NSRP'),(29536,60886,'clearance of cells from fusion plate by epithelial to mesenchymal transition','P','The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.','2013-10-27','NSRP'),(29537,60887,'limb epidermis development','P','The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.','2013-10-27','NSRP'),(29538,60888,'limb epidermis stratification','P','The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.','2013-10-27','NSRP'),(29539,60889,'limb basal epidermal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.','2013-10-27','NSRP'),(29540,60890,'limb spinous cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.','2013-10-27','NSRP'),(29541,60891,'limb granular cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.','2013-10-27','NSRP'),(29542,60892,'limb basal epidermal cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(29543,60893,'limb granular cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(29544,60894,'limb spinous cell fate specification','P','The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.','2013-10-27','NSRP'),(29545,60895,'retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning','P','The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.','2013-10-27','NSRP'),(29546,60896,'neural plate pattern specification','P','The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.','2013-10-27','NSRP'),(29547,60897,'neural plate regionalization','P','The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.','2013-10-27','NSRP'),(29548,60898,'eye field cell fate commitment involved in camera-type eye formation','P','The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.','2013-10-27','NSRP'),(29549,60899,'regulation of transcription involved in eye field cell fate commitment of camera-type eye','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle.','2013-10-27','NSRP'),(29550,60900,'embryonic camera-type eye formation','P','The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.','2013-10-27','NSRP'),(29551,60901,'regulation of hair cycle by canonical Wnt receptor signaling pathway','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.','2013-10-27','NSRP'),(29552,60902,'regulation of hair cycle by BMP signaling pathway','P','A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.','2013-10-27','NSRP'),(29553,60903,'positive regulation of meiosis I','P','Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.','2013-10-27','NSRP'),(29554,60904,'regulation of protein folding in endoplasmic reticulum','P','Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).','2013-10-27','NSRP'),(29555,60905,'regulation of induction of conjugation upon nitrogen starvation','P','Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.','2013-10-27','NSRP'),(29556,60906,'negative regulation of chromatin silencing by small RNA','P','Any process that decreases the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.','2013-10-27','NSRP'),(29557,60907,'positive regulation of macrophage cytokine production','P','Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(29558,60908,'plasmid copy number maintenance','P','The maintenance of the number of copies of extrachromosomal plasmid DNA.','2013-10-27','NSRP'),(29559,60909,'regulation of DNA replication initiation involved in plasmid copy number maintenance','P','Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.','2013-10-27','NSRP'),(29560,60910,'negative regulation of DNA replication initiation involved in plasmid copy number maintenance','P','Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.','2013-10-27','NSRP'),(29561,60911,'cardiac cell fate commitment','P','The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.','2013-10-27','NSRP'),(29562,60912,'cardiac cell fate specification','P','The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.','2013-10-27','NSRP'),(29563,60913,'cardiac cell fate determination','P','The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.','2013-10-27','NSRP'),(29564,60914,'heart formation','P','The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.','2013-10-27','NSRP'),(29565,60915,'mesenchymal cell differentiation involved in lung development','P','The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.','2013-10-27','NSRP'),(29566,60916,'mesenchymal cell proliferation involved in lung development','P','The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.','2013-10-27','NSRP'),(29567,60917,'regulation of (1->6)-beta-D-glucan biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.','2013-10-27','NSRP'),(29568,60918,'auxin transport','P','The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(29569,60919,'auxin influx','P','The process involved in the transport of auxin into the cell.','2013-10-27','NSRP'),(29570,60920,'cardiac pacemaker cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.','2013-10-27','NSRP'),(29571,60921,'sinoatrial node cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.','2013-10-27','NSRP'),(29572,60922,'atrioventricular node cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.','2013-10-27','NSRP'),(29573,60923,'cardiac muscle cell fate commitment','P','The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.','2013-10-27','NSRP'),(29574,60924,'atrial cardiac muscle cell fate commitment','P','The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.','2013-10-27','NSRP'),(29575,60925,'ventricular cardiac muscle cell fate commitment','P','The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.','2013-10-27','NSRP'),(29576,60926,'cardiac pacemaker cell development','P','The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.','2013-10-27','NSRP'),(29577,60927,'cardiac pacemaker cell fate commitment','P','The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.','2013-10-27','NSRP'),(29578,60928,'atrioventricular node cell development','P','The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.','2013-10-27','NSRP'),(29579,60929,'atrioventricular node cell fate commitment','P','The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.','2013-10-27','NSRP'),(29580,60930,'sinoatrial node cell fate commitment','P','The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.','2013-10-27','NSRP'),(29581,60931,'sinoatrial node cell development','P','The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.','2013-10-27','NSRP'),(29582,60932,'His-Purkinje system cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.','2013-10-27','NSRP'),(29583,60933,'His-Purkinje system cell development','P','The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.','2013-10-27','NSRP'),(29584,60934,'His-Purkinje system cell fate commitment','P','The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.','2013-10-27','NSRP'),(29585,60935,'cardiac fibroblast cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29586,60936,'cardiac fibroblast cell development','P','The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29587,60937,'cardiac fibroblast cell fate commitment','P','The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29588,60938,'epicardium-derived cardiac fibroblast cell differentiation','P','The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29589,60939,'epicardium-derived cardiac fibroblast cell development','P','The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29590,60940,'epithelial to mesenchymal transition involved in cardiac fibroblast development','P','A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.','2013-10-27','NSRP'),(29591,60941,'epicardium-derived cardiac fibroblast cell fate commitment','P','The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29592,60942,'neural crest-derived cardiac fibroblast cell differentiation','P','The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29593,60943,'neural crest-derived cardiac fibroblast cell development','P','The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29594,60944,'neural crest-derived cardiac fibroblast cell fate commitment','P','The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.','2013-10-27','NSRP'),(29595,60945,'cardiac neuron differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.','2013-10-27','NSRP'),(29596,60946,'cardiac blood vessel endothelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.','2013-10-27','NSRP'),(29597,60947,'cardiac vascular smooth muscle cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.','2013-10-27','NSRP'),(29598,60948,'cardiac vascular smooth muscle cell development','P','The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.','2013-10-27','NSRP'),(29599,60949,'cardiac vascular smooth muscle cell fate commitment','P','The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.','2013-10-27','NSRP'),(29600,60950,'cardiac glial cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.','2013-10-27','NSRP'),(29601,60951,'neural crest-derived cardiac glial cell differentiation','P','The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.','2013-10-27','NSRP'),(29602,60952,'cardiac glial cell development','P','The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.','2013-10-27','NSRP'),(29603,60953,'cardiac glial cell fate commitment','P','The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.','2013-10-27','NSRP'),(29604,60954,'neural crest-derived cardiac glial cell development','P','The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.','2013-10-27','NSRP'),(29605,60955,'neural crest-derived cardiac glial cell fate commitment','P','The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.','2013-10-27','NSRP'),(29606,60956,'endocardial cell differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.','2013-10-27','NSRP'),(29607,60957,'endocardial cell fate commitment','P','The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.','2013-10-27','NSRP'),(29608,60958,'endocardial cell development','P','The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.','2013-10-27','NSRP'),(29609,60959,'cardiac neuron development','P','The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.','2013-10-27','NSRP'),(29610,60960,'cardiac neuron fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.','2013-10-27','NSRP'),(29611,60961,'phospholipase D inhibitor activity','F','Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.','2013-10-27','NSRP'),(29612,60962,'regulation of ribosomal protein gene transcription from RNA polymerase II promoter','P','Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.','2013-10-27','NSRP'),(29613,60963,'positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter','P','Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.','2013-10-27','NSRP'),(29614,60964,'regulation of gene silencing by miRNA','P','Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.','2013-10-27','NSRP'),(29615,60965,'negative regulation of gene silencing by miRNA','P','Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.','2013-10-27','NSRP'),(29616,60966,'regulation of gene silencing by RNA','P','Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.','2013-10-27','NSRP'),(29617,60967,'negative regulation of gene silencing by RNA','P','Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.','2013-10-27','NSRP'),(29618,60968,'regulation of gene silencing','P','Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.','2013-10-27','NSRP'),(29619,60969,'negative regulation of gene silencing','P','Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.','2013-10-27','NSRP'),(29620,60970,'embryonic heart tube dorsal/ventral pattern formation','P','The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.','2013-10-27','NSRP'),(29621,60971,'embryonic heart tube left/right pattern formation','P','The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.','2013-10-27','NSRP'),(29622,60972,'left/right pattern formation','P','The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.','2013-10-27','NSRP'),(29623,60973,'cell migration involved in heart development','P','The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.','2013-10-27','NSRP'),(29624,60974,'cell migration involved in heart formation','P','The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.','2013-10-27','NSRP'),(29625,60975,'cardioblast migration to the midline involved in heart field formation','P','The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.','2013-10-27','NSRP'),(29626,60976,'coronary vasculature development','P','The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29627,60977,'coronary vasculature morphogenesis','P','The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.','2013-10-27','NSRP'),(29628,60978,'angiogenesis involved in coronary vascular morphogenesis','P','Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.','2013-10-27','NSRP'),(29629,60979,'vasculogenesis involved in coronary vascular morphogenesis','P','The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.','2013-10-27','NSRP'),(29630,60980,'cell migration involved in coronary vasculogenesis','P','The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.','2013-10-27','NSRP'),(29631,60981,'cell migration involved in coronary angiogenesis','P','The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.','2013-10-27','NSRP'),(29632,60982,'coronary artery morphogenesis','P','The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.','2013-10-27','NSRP'),(29633,60983,'epicardium-derived cardiac vascular smooth muscle cell differentiation','P','The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.','2013-10-27','NSRP'),(29634,60984,'epicardium-derived cardiac vascular smooth muscle cell development','P','The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.','2013-10-27','NSRP'),(29635,60985,'epicardium-derived cardiac vascular smooth muscle cell fate commitment','P','The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.','2013-10-27','NSRP'),(29636,60986,'endocrine hormone secretion','P','The regulated release of a hormone into the circulatory system.','2013-10-27','NSRP'),(29637,60987,'lipid tube','C','A macromolecular complex that contains a tube of lipid surrounded by a protein coat.','2013-10-27','NSRP'),(29638,60988,'lipid tube assembly','P','The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as the fuse or undergo fission.','2013-10-27','NSRP'),(29639,60989,'lipid tube assembly involved in organelle fusion','P','The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.','2013-10-27','NSRP'),(29640,60990,'lipid tube assembly involved in organelle fission','P','The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.','2013-10-27','NSRP'),(29641,60991,'lipid tube assembly involved in cytokinesis','P','The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in cytokinesis.','2013-10-27','NSRP'),(29642,60992,'response to fungicide','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.','2013-10-27','NSRP'),(29643,60993,'kidney morphogenesis','P','Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.','2013-10-27','NSRP'),(29644,60994,'regulation of transcription from RNA polymerase II promoter involved in kidney development','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state.','2013-10-27','NSRP'),(29645,60995,'cell-cell signaling involved in kidney development','P','Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.','2013-10-27','NSRP'),(29646,60996,'dendritic spine development','P','The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.','2013-10-27','NSRP'),(29647,60997,'dendritic spine morphogenesis','P','The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.','2013-10-27','NSRP'),(29648,60998,'regulation of dendritic spine development','P','Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29649,60999,'positive regulation of dendritic spine development','P','Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29650,61000,'negative regulation of dendritic spine development','P','Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29651,61001,'regulation of dendritic spine morphogenesis','P','Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.','2013-10-27','NSRP'),(29652,61002,'negative regulation of dendritic spine morphogenesis','P','Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.','2013-10-27','NSRP'),(29653,61003,'positive regulation of dendritic spine morphogenesis','P','Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.','2013-10-27','NSRP'),(29654,61004,'pattern specification involved in kidney development','P','Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.','2013-10-27','NSRP'),(29655,61005,'cell differentiation involved in kidney development','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29656,61006,'regulation of cell proliferation involved in kidney morphogenesis','P','Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.','2013-10-27','NSRP'),(29657,61007,'hepaticobiliary system process','P','An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.','2013-10-27','NSRP'),(29658,61008,'hepaticobiliary system development','P','The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.','2013-10-27','NSRP'),(29659,61009,'common bile duct development','P','The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.','2013-10-27','NSRP'),(29660,61010,'gall bladder development','P','The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.','2013-10-27','NSRP'),(29661,61011,'hepatic duct development','P','The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.','2013-10-27','NSRP'),(29662,61013,'regulation of mRNA catabolic process','P','Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3\',5\'-phosphodiester linkage.','2013-10-27','NSRP'),(29663,61014,'positive regulation of mRNA catabolic process','P','Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3\',5\'-phosphodiester linkage.','2013-10-27','NSRP'),(29664,61015,'snRNA import into nucleus','P','The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.','2013-10-27','NSRP'),(29665,61016,'snRNA import into Cajal body','P','The directed movement of snRNA, small nuclear ribonucleic acid, into a Cajal body.','2013-10-27','NSRP'),(29666,61017,'hepatoblast differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.','2013-10-27','NSRP'),(29667,61024,'membrane organization','P','A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.','2013-10-27','NSRP'),(29668,61025,'membrane fusion','P','The membrane organization process that joins two lipid bilayers to form a single membrane.','2013-10-27','NSRP'),(29669,61026,'cardiac muscle tissue regeneration','P','The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.','2013-10-27','NSRP'),(29670,61027,'umbilical cord development','P','The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.','2013-10-27','NSRP'),(29671,61028,'establishment of endothelial barrier','P','The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.','2013-10-27','NSRP'),(29672,61029,'eyelid development in camera-type eye','P','The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.','2013-10-27','NSRP'),(29673,61030,'epithelial cell differentiation involved in mammary gland alveolus development','P','The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.','2013-10-27','NSRP'),(29674,61031,'endodermal digestive tract morphogenesis','P','The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.','2013-10-27','NSRP'),(29675,61032,'visceral serous pericardium development','P','The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.','2013-10-27','NSRP'),(29676,61033,'secretion by lung epithelial cell involved in lung growth','P','The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.','2013-10-27','NSRP'),(29677,61034,'olfactory bulb mitral cell layer development','P','The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.','2013-10-27','NSRP'),(29678,61035,'regulation of cartilage development','P','Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(29679,61036,'positive regulation of cartilage development','P','Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(29680,61037,'negative regulation of cartilage development','P','Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.','2013-10-27','NSRP'),(29681,61038,'uterus morphogenesis','P','The process in which anatomical structures of the uterus are generated and organized.','2013-10-27','NSRP'),(29682,61039,'ovum-producing ovary development','P','The process whose specific outcome is the progression of an ovary that produces an ovum over time, from its formation to the mature structure.','2012-03-14','NSRP'),(29683,61040,'female gonad morphogenesis','P','The process in which a female gonad is generated and organized.','2013-10-27','NSRP'),(29684,61041,'regulation of wound healing','P','Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.','2013-10-27','NSRP'),(29685,61042,'vascular wound healing','P','Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.','2013-10-27','NSRP'),(29686,61043,'regulation of vascular wound healing','P','Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.','2013-10-27','NSRP'),(29687,61044,'negative regulation of vascular wound healing','P','Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.','2013-10-27','NSRP'),(29688,61045,'negative regulation of wound healing','P','Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.','2013-10-27','NSRP'),(29689,61046,'regulation of branching involved in lung morphogenesis','P','Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.','2013-10-27','NSRP'),(29690,61047,'positive regulation of branching involved in lung morphogenesis','P','Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.','2013-10-27','NSRP'),(29691,61048,'negative regulation of branching involved in lung morphogenesis','P','Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.','2013-10-27','NSRP'),(29692,61049,'cell growth involved in cardiac muscle cell development','P','The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.','2013-10-27','NSRP'),(29693,61050,'regulation of cell growth involved in cardiac muscle cell development','P','Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.','2013-10-27','NSRP'),(29694,61051,'positive regulation of cell growth involved in cardiac muscle cell development','P','Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.','2013-10-27','NSRP'),(29695,61052,'negative regulation of cell growth involved in cardiac muscle cell development','P','Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.','2013-10-27','NSRP'),(29696,61053,'somite development','P','The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.','2013-10-27','NSRP'),(29697,61054,'dermatome development','P','The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.','2013-10-27','NSRP'),(29698,61055,'myotome development','P','The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.','2013-10-27','NSRP'),(29699,61056,'sclerotome development','P','The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.','2013-10-27','NSRP'),(29700,61057,'peptidoglycan recognition protein signaling pathway','P','A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.','2013-10-27','NSRP'),(29701,61058,'regulation of peptidoglycan recognition protein signaling pathway','P','Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.','2013-10-27','NSRP'),(29702,61059,'positive regulation of peptidoglycan recognition protein signaling pathway','P','Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.','2013-10-27','NSRP'),(29703,61060,'negative regulation of peptidoglycan recognition protein signaling pathway','P','Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.','2013-10-27','NSRP'),(29704,61061,'muscle structure development','P','The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.','2013-10-27','NSRP'),(29705,61062,'regulation of nematode larval development','P','Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.','2013-10-27','NSRP'),(29706,61063,'positive regulation of nematode larval development','P','Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.','2013-10-27','NSRP'),(29707,61064,'negative regulation of nematode larval development','P','Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.','2013-10-27','NSRP'),(29708,61065,'regulation of dauer larval development','P','Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.','2013-10-27','NSRP'),(29709,61066,'positive regulation of dauer larval development','P','Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.','2013-10-27','NSRP'),(29710,61067,'negative regulation of dauer larval development','P','Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.','2013-10-27','NSRP'),(29711,61068,'urethra development','P','The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.','2013-10-27','NSRP'),(29712,61069,'male urethra development','P','The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.','2013-10-27','NSRP'),(29713,61070,'female urethra development','P','The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.','2013-10-27','NSRP'),(29714,61071,'urethra epithelium development','P','The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.','2013-10-27','NSRP'),(29715,61072,'iris morphogenesis','P','The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.','2013-10-27','NSRP'),(29716,61073,'ciliary body morphogenesis','P','The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.','2013-10-27','NSRP'),(29717,61074,'regulation of neural retina development','P','Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.','2013-10-27','NSRP'),(29718,61075,'positive regulation of neural retina development','P','Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.','2013-10-27','NSRP'),(29719,61076,'negative regulation of neural retina development','P','Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.','2013-10-27','NSRP'),(29720,61077,'chaperone-mediated protein folding','P','The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.','2013-10-27','NSRP'),(29721,61078,'positive regulation of prostaglandin secretion involved in immune response','P','Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.','2013-10-27','NSRP'),(29722,61079,'left horn of sinus venosus development','P','The progression of the left horn of the sinus venosus from its initial formation to the mature structure.','2013-10-27','NSRP'),(29723,61080,'right horn of sinus venosus development','P','The progression of the right horn of the sinus venosus from its formation to the mature structure.','2013-10-27','NSRP'),(29724,61081,'positive regulation of myeloid leukocyte cytokine production involved in immune response','P','Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.','2013-10-27','NSRP'),(29725,61082,'myeloid leukocyte cytokine production','P','Any process that contributes to cytokine production by a myeloid cell.','2013-10-27','NSRP'),(29726,61083,'regulation of protein refolding','P','Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.','2013-10-27','NSRP'),(29727,61084,'negative regulation of protein refolding','P','Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.','2013-10-27','NSRP'),(29728,61085,'regulation of histone H3-K27 methylation','P','Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.','2013-10-27','NSRP'),(29729,61086,'negative regulation of histone H3-K27 methylation','P','Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.','2013-10-27','NSRP'),(29730,61087,'positive regulation of histone H3-K27 methylation','P','Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.','2013-10-27','NSRP'),(29731,61088,'regulation of sequestering of zinc ion','P','Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(29732,61089,'negative regulation of sequestering of zinc ion','P','Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(29733,61090,'positive regulation of sequestering of zinc ion','P','Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.','2013-10-27','NSRP'),(29734,61091,'regulation of phospholipid translocation','P','Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.','2013-10-27','NSRP'),(29735,61092,'positive regulation of phospholipid translocation','P','Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.','2013-10-27','NSRP'),(29736,61093,'negative regulation of phospholipid translocation','P','Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.','2013-10-27','NSRP'),(29737,61094,'regulation of turning behavior involved in mating','P','Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner\'s vulva. Turning occurs via a sharp ventral coil of the male\'s tail.','2013-10-27','NSRP'),(29738,61095,'positive regulation of turning behavior involved in mating','P','Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner\'s vulva. Turning occurs via a sharp ventral coil of the male\'s tail.','2013-10-27','NSRP'),(29739,61096,'negative regulation of turning behavior involved in mating','P','Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner\'s vulva. Turning occurs via a sharp ventral coil of the male\'s tail.','2013-10-27','NSRP'),(29740,61097,'regulation of protein tyrosine kinase activity','P','Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.','2013-10-27','NSRP'),(29741,61098,'positive regulation of protein tyrosine kinase activity','P','Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.','2013-10-27','NSRP'),(29742,61099,'negative regulation of protein tyrosine kinase activity','P','Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.','2013-10-27','NSRP'),(29743,61100,'lung neuroendocrine cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.','2013-10-27','NSRP'),(29744,61101,'neuroendocrine cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.','2013-10-27','NSRP'),(29745,61102,'stomach neuroendocrine cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.','2013-10-27','NSRP'),(29746,61103,'carotid body glomus cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.','2013-10-27','NSRP'),(29747,61104,'adrenal chromaffin cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.','2013-10-27','NSRP'),(29748,61105,'regulation of stomach neuroendocrine cell differentiation','P','Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.','2013-10-27','NSRP'),(29749,61106,'negative regulation of stomach neuroendocrine cell differentiation','P','Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.','2013-10-27','NSRP'),(29750,61107,'seminal vesicle development','P','The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.','2013-10-27','NSRP'),(29751,61108,'seminal vesicle epithelium development','P','The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29752,61109,'dense core granule organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.','2013-10-27','NSRP'),(29753,61110,'dense core granule biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.','2013-10-27','NSRP'),(29754,61111,'epithelial-mesenchymal cell signaling involved in lung development','P','Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.','2013-10-27','NSRP'),(29755,61112,'negative regulation of bud outgrowth involved in lung branching','P','Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.','2013-10-27','NSRP'),(29756,61113,'pancreas morphogenesis','P','Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.','2013-10-27','NSRP'),(29757,61114,'branching involved in pancreas morphogenesis','P','The process in which the branches of the pancreas are generated and organized.','2013-10-27','NSRP'),(29758,61115,'lung proximal/distal axis specification','P','The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.','2013-10-27','NSRP'),(29759,61116,'ductus venosus closure','P','The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.','2013-10-27','NSRP'),(29760,61117,'negative regulation of heart growth','P','Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.','2013-10-27','NSRP'),(29761,61118,'regulation of positive chemotaxis to cAMP','P','Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP.','2013-10-27','NSRP'),(29762,61119,'regulation of positive chemotaxis to cAMP by chlorinated alkylphenone','P','Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.','2013-10-27','NSRP'),(29763,61120,'regulation of positive chemotaxis to cAMP by DIF-1','P','Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29764,61121,'regulation of positive chemotaxis to cAMP by DIF-2','P','Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29765,61122,'positive regulation of positive chemotaxis to cAMP','P','Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP.','2013-10-27','NSRP'),(29766,61123,'negative regulation of positive chemotaxis to cAMP','P','Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP.','2013-10-27','NSRP'),(29767,61124,'positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone','P','Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.','2013-10-27','NSRP'),(29768,61125,'negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone','P','Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.','2013-10-27','NSRP'),(29769,61126,'positive regulation of positive chemotaxis to cAMP by DIF-1','P','Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29770,61127,'negative regulation of positive chemotaxis to cAMP by DIF-1','P','Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29771,61128,'positive regulation of chemotaxis to cAMP by DIF-2','P','Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29772,61129,'negative regulation of positive chemotaxis to cAMP by DIF-2','P','Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3\',5\'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.','2013-10-27','NSRP'),(29773,61130,'pancreatic bud formation','P','The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.','2013-10-27','NSRP'),(29774,61131,'pancreas field specification','P','The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.','2013-10-27','NSRP'),(29775,61132,'pancreas induction','P','The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.','2013-10-27','NSRP'),(29776,61133,'endopeptidase activator activity','F','Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.','2013-10-27','NSRP'),(29777,61134,'peptidase regulator activity','F','Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.','2013-10-27','NSRP'),(29778,61135,'endopeptidase regulator activity','F','Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.','2013-10-27','NSRP'),(29779,61136,'regulation of proteasomal protein catabolic process','P','Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.','2013-10-27','NSRP'),(29780,61137,'bud dilation','P','The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.','2013-10-27','NSRP'),(29781,61138,'morphogenesis of a branching epithelium','P','The process in which the anatomical structures of a branched epithelium are generated and organized.','2013-10-27','NSRP'),(29782,61139,'bud field specification','P','The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(29783,61140,'lung secretory cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.','2013-10-27','NSRP'),(29784,61141,'lung ciliated cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains a motile cilium for moving substances released from lung secretory cells.','2013-10-27','NSRP'),(29785,61142,'mesothelial-mesenchymal cell signaling involved in early lung development','P','Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.','2013-10-27','NSRP'),(29786,61143,'alveolar primary septum development','P','The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.','2013-10-27','NSRP'),(29787,61144,'alveolar secondary septum development','P','The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.','2013-10-27','NSRP'),(29788,61145,'lung smooth muscle development','P','The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29789,61146,'Peyer\'s patch morphogenesis','P','The process in which a Peyer\'s patch is generated and organized. Peyer\'s patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.','2013-10-27','NSRP'),(29790,61147,'endocardial endothelium development','P','The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.','2013-10-27','NSRP'),(29791,61148,'extracellular matrix organization involved in endocardium development','P','A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.','2013-10-27','NSRP'),(29792,61149,'BMP signaling pathway involved in ureter morphogenesis','P','A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.','2013-10-27','NSRP'),(29793,61150,'renal system segmentation','P','The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.','2013-10-27','NSRP'),(29794,61151,'BMP signaling pathway involved in renal system segmentation','P','A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.','2013-10-27','NSRP'),(29795,61152,'trachea submucosa development','P','The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.','2013-10-27','NSRP'),(29796,61153,'trachea gland development','P','The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.','2013-10-27','NSRP'),(29797,61154,'endothelial tube morphogenesis','P','The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.','2013-10-27','NSRP'),(29798,61155,'pulmonary artery endothelial tube morphogenesis','P','The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.','2013-10-27','NSRP'),(29799,61156,'pulmonary artery morphogenesis','P','The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.','2013-10-27','NSRP'),(29800,61157,'mRNA destabilization','P','Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.','2013-10-27','NSRP'),(29801,61158,'3\'-UTR-mediated mRNA destabilization','P','An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3\'-untranslated region (UTR) of an mRNA.','2013-10-27','NSRP'),(29802,61159,'establishment of bipolar cell polarity involved in cell morphogenesis','P','The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.','2013-10-27','NSRP'),(29803,61160,'regulation of establishment of bipolar cell polarity regulating cell shape','P','Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.','2013-10-27','NSRP'),(29804,61161,'positive regulation of establishment of bipolar cell polarity regulating cell shape','P','Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.','2013-10-27','NSRP'),(29805,61162,'establishment of monopolar cell polarity','P','The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.','2013-10-27','NSRP'),(29806,61163,'endoplasmic reticulum polarization','P','The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell.','2013-10-27','NSRP'),(29807,61164,'transitional endoplasmic reticulum polarization at cell division site','P','The endoplasmic reticulum polarization process that results in the structure being polarized at the site of future cell division.','2013-10-27','NSRP'),(29808,61165,'endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site','P','The process in which endoplasmic reticulum is transiently localized to the site where a cell will divide.','2013-10-27','NSRP'),(29809,61166,'establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site','P','The directed movement of the endoplasmic reticulum to the site where a cell will divide.','2013-10-27','NSRP'),(29810,61167,'maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site','P','The process in which the endoplasmic reticulum is maintained at the site of cell division and is prevented from moving elsewhere.','2013-10-27','NSRP'),(29811,61168,'regulation of hair follicle placode formation','P','Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.','2013-10-27','NSRP'),(29812,61169,'positive regulation of hair placode formation','P','Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.','2013-10-27','NSRP'),(29813,61170,'negative regulation of hair follicle placode formation','P','Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.','2013-10-27','NSRP'),(29814,61171,'establishment of bipolar cell polarity','P','The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.','2013-10-27','NSRP'),(29815,61172,'regulation of establishment of bipolar cell polarity','P','Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.','2013-10-27','NSRP'),(29816,61173,'positive regulation of establishment of bipolar cell polarity','P','Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.','2013-10-27','NSRP'),(29817,61174,'type I terminal bouton','C','Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.','2013-10-27','NSRP'),(29818,61175,'type II terminal bouton','C','Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.','2013-10-27','NSRP'),(29819,61176,'type Ib terminal bouton','C','Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.','2013-10-27','NSRP'),(29820,61177,'type Is terminal bouton','C','Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.','2013-10-27','NSRP'),(29821,61178,'regulation of insulin secretion involved in cellular response to glucose stimulus','P','Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.','2013-10-27','NSRP'),(29822,61179,'negative regulation of insulin secretion involved in cellular response to glucose stimulus','P','Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.','2013-10-27','NSRP'),(29823,61180,'mammary gland epithelium development','P','The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.','2013-10-27','NSRP'),(29824,61181,'regulation of chondrocyte development','P','Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.','2013-10-27','NSRP'),(29825,61182,'negative regulation of chondrocyte development','P','Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.','2013-10-27','NSRP'),(29826,61183,'regulation of dermatome development','P','Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.','2013-10-27','NSRP'),(29827,61184,'positive regulation of dermatome development','P','Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.','2013-10-27','NSRP'),(29828,61185,'negative regulation of dermatome development','P','Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.','2013-10-27','NSRP'),(29829,61186,'negative regulation of chromatin silencing at silent mating-type cassette','P','Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.','2013-10-27','NSRP'),(29830,61187,'regulation of chromatin silencing at rDNA','P','Any process that modulates the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin.','2013-10-27','NSRP'),(29831,61188,'negative regulation of chromatin silencing at rDNA','P','Any process that decreases the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin.','2013-10-27','NSRP'),(29832,61189,'positive regulation of sclerotome development','P','Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.','2013-10-27','NSRP'),(29833,61190,'regulation of sclerotome development','P','Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.','2013-10-27','NSRP'),(29834,61191,'positive regulation of vacuole fusion, non-autophagic','P','Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.','2013-10-27','NSRP'),(29835,61192,'negative regulation of vacuole fusion, non-autophagic','P','Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.','2013-10-27','NSRP'),(29836,61193,'taste bud development','P','The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.','2013-10-27','NSRP'),(29837,61194,'taste bud morphogenesis','P','The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.','2013-10-27','NSRP'),(29838,61195,'taste bud formation','P','The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.','2013-10-27','NSRP'),(29839,61196,'fungiform papilla development','P','The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.','2013-10-27','NSRP'),(29840,61197,'fungiform papilla morphogenesis','P','The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.','2013-10-27','NSRP'),(29841,61198,'fungiform papilla formation','P','The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.','2013-10-27','NSRP'),(29842,61199,'striated muscle contraction involved in embryonic body morphogenesis','P','The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo\'s characteristic body morphology.','2013-10-27','NSRP'),(29843,61200,'clathrin-sculpted gamma-aminobutyric acid transport vesicle','C','A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.','2013-10-27','NSRP'),(29844,61201,'clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen','C','The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.','2013-10-27','NSRP'),(29845,61202,'clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane','C','The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.','2013-10-27','NSRP'),(29846,61203,'striated muscle paramyosin thick filament assembly','P','The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.','2013-10-27','NSRP'),(29847,61204,'paramyosin filament assembly or disassembly','P','The formation or disassembly of a filament composed of paramyosin molecules.','2013-10-27','NSRP'),(29848,61205,'paramesonephric duct development','P','The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.','2013-10-27','NSRP'),(29849,61206,'mesonephros morphogenesis','P','The process in which the anatomical structures of the mesonephros are generated and organized.','2013-10-27','NSRP'),(29850,61207,'mesonephric juxtaglomerulus cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29851,61208,'cell differentiation involved in mesonephros development','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29852,61209,'cell proliferation involved in mesonephros development','P','The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.','2013-10-27','NSRP'),(29853,61210,'cell-cell signaling involved in mesonephros development','P','Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.','2013-10-27','NSRP'),(29854,61211,'mesonephric collecting duct development','P','The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.','2013-10-27','NSRP'),(29855,61212,'mesonephric juxtaglomerular apparatus development','P','The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.','2013-10-27','NSRP'),(29856,61213,'positive regulation of mesonephros development','P','Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.','2013-10-27','NSRP'),(29857,61214,'mesonephric smooth muscle tissue development','P','The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29858,61215,'mesonephric nephron development','P','The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.','2013-10-27','NSRP'),(29859,61216,'regulation of transcription from RNA polymerase II promoter involved in mesonephros development','P','Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state.','2013-10-27','NSRP'),(29860,61217,'regulation of mesonephros development','P','Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.','2013-10-27','NSRP'),(29861,61218,'negative regulation of mesonephros development','P','Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.','2013-10-27','NSRP'),(29862,61219,'mesonephric mesenchyme development','P','The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.','2013-10-27','NSRP'),(29863,61220,'mesonephric macula densa development','P','The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.','2013-10-27','NSRP'),(29864,61221,'mesonephric mesenchyme morphogenesis','P','The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.','2013-10-27','NSRP'),(29865,61222,'mesonephric mesenchymal cell proliferation involved in mesonephros development','P','The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.','2013-10-27','NSRP'),(29866,61223,'mesonephric mesenchymal cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29867,61224,'mesonephric glomerulus development','P','The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman\'s capsule in nephrons of the mature vertebrate kidney, or mesonephros.','2013-10-27','NSRP'),(29868,61225,'mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development','P','The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.','2013-10-27','NSRP'),(29869,61226,'proximal/distal pattern formation involved in mesonephric nephron development','P','The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).','2013-10-27','NSRP'),(29870,61227,'pattern specification involved in mesonephros development','P','Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.','2013-10-27','NSRP'),(29871,61228,'mesonephric nephron morphogenesis','P','The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.','2013-10-27','NSRP'),(29872,61229,'mesonephric juxtaglomerulus cell development','P','The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29873,61230,'mesonephric juxtaglomerulus cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.','2013-10-27','NSRP'),(29874,61231,'mesonephric glomerulus vasculature development','P','The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.','2013-10-27','NSRP'),(29875,61232,'mesonephric glomerular epithelium development','P','The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.','2013-10-27','NSRP'),(29876,61233,'mesonephric glomerular basement membrane development','P','The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.','2013-10-27','NSRP'),(29877,61234,'mesonephric glomerulus morphogenesis','P','The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman\'s capsule in nephrons of the vertebrate mesonephros.','2013-10-27','NSRP'),(29878,61235,'mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis','P','The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.','2013-10-27','NSRP'),(29879,61236,'mesonephric comma-shaped body morphogenesis','P','The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.','2013-10-27','NSRP'),(29880,61237,'convergent extension involved in mesonephric nephron morphogenesis','P','The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.','2013-10-27','NSRP'),(29881,61238,'establishment of planar polarity involved in mesonephric nephron morphogenesis','P','Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.','2013-10-27','NSRP'),(29882,61239,'mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis','P','The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.','2013-10-27','NSRP'),(29883,61240,'mesonephric nephron tubule morphogenesis','P','The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.','2013-10-27','NSRP'),(29884,61241,'mesonephric nephron epithelium development','P','The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.','2013-10-27','NSRP'),(29885,61242,'mesonephric nephron tubule development','P','The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.','2013-10-27','NSRP'),(29886,61243,'mesonephric renal vesicle morphogenesis','P','The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.','2013-10-27','NSRP'),(29887,61244,'mesonephric S-shaped body morphogenesis','P','The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.','2013-10-27','NSRP'),(29888,61245,'establishment or maintenance of bipolar cell polarity','P','Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.','2013-10-27','NSRP'),(29889,61246,'establishment or maintenance of bipolar cell polarity regulating cell shape','P','Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.','2013-10-27','NSRP'),(29890,61247,'mesonephric glomerular mesangium development','P','The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.','2013-10-27','NSRP'),(29891,61248,'mesonephric glomerulus vasculature morphogenesis','P','The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.','2013-10-27','NSRP'),(29892,61249,'mesonephric glomerular capillary formation','P','The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.','2013-10-27','NSRP'),(29893,61250,'mesonephric glomerular epithelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.','2013-10-27','NSRP'),(29894,61251,'mesonephric glomerular epithelial cell development','P','The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.','2013-10-27','NSRP'),(29895,61252,'mesonephric glomerular epithelial cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.','2013-10-27','NSRP'),(29896,61253,'mesonephric glomerular parietal epithelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.','2013-10-27','NSRP'),(29897,61254,'mesonephric glomerular parietal epithelial cell development','P','The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.','2013-10-27','NSRP'),(29898,61255,'mesonephric glomerular parietal epithelial cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.','2013-10-27','NSRP'),(29899,61256,'mesonephric glomerular visceral epithelial cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.','2013-10-27','NSRP'),(29900,61257,'mesonephric glomerular visceral epithelial cell development','P','The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.','2013-10-27','NSRP'),(29901,61258,'mesonephric glomerular visceral epithelial cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.','2013-10-27','NSRP'),(29902,61259,'mesonephric glomerular mesangial cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29903,61260,'mesonephric mesangial cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29904,61261,'mesenchymal to epithelial transition involved in mesonephros morphogenesis','P','A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.','2013-10-27','NSRP'),(29905,61262,'mesonephric renal vesicle formation','P','The developmental process pertaining to the initial formation of the mesonephros.','2013-10-27','NSRP'),(29906,61263,'mesonephric glomerular mesangial cell development','P','The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29907,61264,'mesonephric glomerular mesangial cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.','2013-10-27','NSRP'),(29908,61265,'mesonephric nephron tubule epithelial cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29909,61266,'mesonephric interstitial cell differentiation','P','The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial cells of the mesonephros as it progresses from its formation to the mature state.','2013-10-27','NSRP'),(29910,61267,'mesonephric interstitial cell development','P','The process whose specific outcome is the progression of a mesonephric interstitial cell over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29911,61268,'mesonephric interstitial cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial cell.','2013-10-27','NSRP'),(29912,61269,'mesonephric glomerular mesangial cell proliferation involved in mesonephros development','P','The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.','2013-10-27','NSRP'),(29913,61270,'mesonephric intraglomerular mesangial cell proliferation','P','The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.','2013-10-27','NSRP'),(29914,61271,'mesenchymal to epithelial transition involved in mesonephric renal vesicle formation','P','A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.','2013-10-27','NSRP'),(29915,61272,'mesonephric connecting tubule development','P','The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.','2013-10-27','NSRP'),(29916,61273,'mesonephric distal tubule morphogenesis','P','The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.','2013-10-27','NSRP'),(29917,61274,'mesonephric distal tubule development','P','The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.','2013-10-27','NSRP'),(29918,61275,'mesonephric proximal tubule development','P','The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.','2013-10-27','NSRP'),(29919,61276,'mesonephric proximal tubule morphogenesis','P','The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.','2013-10-27','NSRP'),(29920,61277,'mesonephric nephron tubule formation','P','The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.','2013-10-27','NSRP'),(29921,61278,'epithelial cell migration involved in mesonephric nephron tubule morphogenesis','P','The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.','2013-10-27','NSRP'),(29922,61279,'epithelial cell migration involved in mesonephric distal tubule morphogenesis','P','The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.','2013-10-27','NSRP'),(29923,61280,'epithelial cell migration involved in mesonephric proximal tubule morphogenesis','P','The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.','2013-10-27','NSRP'),(29924,61281,'specification of mesonephric connecting tubule identity','P','The process in which the connecting tubule of the mesonephric nephron acquires its identity.','2013-10-27','NSRP'),(29925,61282,'specification of mesonephric nephron tubule identity','P','The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.','2013-10-27','NSRP'),(29926,61283,'specification of mesonephric distal tubule identity','P','The process in which the distal tubule of the mesonephric nephron acquires its identity.','2013-10-27','NSRP'),(29927,61284,'specification of mesonephric proximal tubule identity','P','The process in which the proximal tubule of the mesonephric nephron acquires its identity.','2013-10-27','NSRP'),(29928,61285,'mesonephric capsule development','P','The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.','2013-10-27','NSRP'),(29929,61286,'mesonephric capsule morphogenesis','P','The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.','2013-10-27','NSRP'),(29930,61287,'mesonephric capsule formation','P','The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.','2013-10-27','NSRP'),(29931,61288,'mesonephric capsule specification','P','The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.','2013-10-27','NSRP'),(29932,61289,'Wnt receptor signaling pathway involved in kidney development','P','The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.','2013-10-27','NSRP'),(29933,61290,'canonical Wnt receptor signaling pathway involved in metanephric kidney development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29934,61291,'canonical Wnt receptor signaling pathway involved in ureteric bud branching','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29935,61292,'canonical Wnt receptor signaling pathway involved in mesonephros development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29936,61293,'canonical Wnt receptor signaling pathway involved in mesonephric nephron development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29937,61294,'mesonephric renal vesicle induction','P','Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.','2013-10-27','NSRP'),(29938,61295,'regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis','P','Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.','2013-10-27','NSRP'),(29939,61296,'negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis','P','Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.','2013-10-27','NSRP'),(29940,61297,'positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis','P','Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.','2013-10-27','NSRP'),(29941,61298,'retina vasculature development in camera-type eye','P','The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29942,61299,'retina vasculature morphogenesis in camera-type eye','P','The process in which the vasculature of the retina is generated and organized.','2013-10-27','NSRP'),(29943,61300,'cerebellum vasculature development','P','The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29944,61301,'cerebellum vasculature morphogenesis','P','The process in which the vasculature of the cerebellum is generated and organized.','2013-10-27','NSRP'),(29945,61302,'smooth muscle cell-matrix adhesion','P','The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.','2013-10-27','NSRP'),(29946,61303,'cornea development in camera-type eye','P','The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.','2013-10-27','NSRP'),(29947,61304,'retinal blood vessel morphogenesis','P','The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.','2013-10-27','NSRP'),(29948,61305,'maintenance of bipolar cell polarity regulating cell shape','P','The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.','2013-10-27','NSRP'),(29949,61306,'DNA strand renaturation involved in double-strand break repair','P','The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair.','2013-10-27','NSRP'),(29950,61307,'cardiac neural crest cell differentiation involved in heart development','P','The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.','2013-10-27','NSRP'),(29951,61308,'cardiac neural crest cell development involved in heart development','P','The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.','2013-10-27','NSRP'),(29952,61309,'cardiac neural crest cell development involved in outflow tract morphogenesis','P','The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.','2013-10-27','NSRP'),(29953,61310,'canonical Wnt receptor signaling pathway involved in cardiac neural crest cell differentiation involved in heart development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.','2013-10-27','NSRP'),(29954,61311,'cell surface receptor signaling pathway involved in heart development','P','Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time.','2013-10-27','NSRP'),(29955,61312,'BMP signaling pathway involved in heart development','P','A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.','2013-10-27','NSRP'),(29956,61313,'fibroblast growth factor receptor signaling pathway involved in heart development','P','The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.','2013-10-27','NSRP'),(29957,61314,'Notch signaling involved in heart development','P','The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.','2013-10-27','NSRP'),(29958,61315,'canonical Wnt receptor signaling pathway involved in positive regulation of cardiac muscle cell proliferation','P','The canonical Wnt receptor signaling pathway that contributes to an expansion of the population of cardiac muscle cells.','2013-10-27','NSRP'),(29959,61316,'canonical Wnt receptor signaling pathway involved in heart development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29960,61317,'canonical Wnt receptor signaling pathway involved in cardiac muscle cell fate commitment','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.','2013-10-27','NSRP'),(29961,61318,'renal filtration cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.','2013-10-27','NSRP'),(29962,61319,'nephrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.','2013-10-27','NSRP'),(29963,61320,'pericardial nephrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.','2013-10-27','NSRP'),(29964,61321,'garland nephrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.','2013-10-27','NSRP'),(29965,61322,'disseminated nephrocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.','2013-10-27','NSRP'),(29966,61323,'cell proliferation involved in heart morphogenesis','P','The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.','2013-10-27','NSRP'),(29967,61324,'canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation','P','The canonical Wnt receptor signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.','2013-10-27','NSRP'),(29968,61325,'cell proliferation involved in outflow tract morphogenesis','P','The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.','2013-10-27','NSRP'),(29969,61326,'renal tubule development','P','The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.','2013-10-27','NSRP'),(29970,61327,'anterior Malpighian tubule development','P','The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.','2013-10-27','NSRP'),(29971,61328,'posterior Malpighian tubule development','P','The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.','2013-10-27','NSRP'),(29972,61329,'Malpighian tubule principal cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.','2013-10-27','NSRP'),(29973,61330,'Malpighian tubule stellate cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.','2013-10-27','NSRP'),(29974,61331,'epithelial cell proliferation involved in Malpighian tubule morphogenesis','P','The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.','2013-10-27','NSRP'),(29975,61332,'Malpighian tubule bud morphogenesis','P','The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.','2013-10-27','NSRP'),(29976,61333,'renal tubule morphogenesis','P','The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.','2013-10-27','NSRP'),(29977,61334,'cell rearrangement involved in Malpighian tubule morphogenesis','P','The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.','2013-10-27','NSRP'),(29978,61335,'cell growth involved in Malpighian tubule morphogenesis','P','The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.','2013-10-27','NSRP'),(29979,61336,'cell morphogenesis involved in Malpighian tubule morphogenesis','P','The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.','2013-10-27','NSRP'),(29980,61337,'cardiac conduction','P','Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.','2013-10-27','NSRP'),(29981,61338,'atrioventricular node impulse conduction delay','P','Obsolete. A heart process that modulates the propagation of the signal that causes the heart muscle to contract.','2013-10-27','NSRP'),(29982,61339,'establishment or maintenance of monopolar cell polarity','P','Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.','2013-10-27','NSRP'),(29983,61340,'establishment or maintenance of monopolar cell polarity regulating cell shape','P','Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.','2013-10-27','NSRP'),(29984,61341,'non-canonical Wnt receptor signaling pathway involved in heart development','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.','2013-10-27','NSRP'),(29985,61342,'regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway','P','Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.','2013-10-27','NSRP'),(29986,61343,'cell adhesion involved in heart morphogenesis','P','The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.','2013-10-27','NSRP'),(29987,61344,'regulation of cell adhesion involved in heart morphogenesis','P','Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.','2013-10-27','NSRP'),(29988,61345,'planar cell polarity pathway involved in cardiac muscle cell fate commitment','P','The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.','2013-10-27','NSRP'),(29989,61346,'planar cell polarity pathway involved in heart morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.','2013-10-27','NSRP'),(29990,61347,'planar cell polarity pathway involved in outflow tract morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.','2013-10-27','NSRP'),(29991,61348,'planar cell polarity pathway involved in ventricular septum morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.','2013-10-27','NSRP'),(29992,61349,'planar cell polarity pathway involved in cardiac right atrium morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.','2013-10-27','NSRP'),(29993,61350,'planar cell polarity pathway involved in cardiac muscle tissue morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.','2013-10-27','NSRP'),(29994,61351,'neural precursor cell proliferation','P','The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.','2013-10-27','NSRP'),(29995,61352,'cell chemotaxis involved in Malpighian tubule morphogenesis','P','The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.','2013-10-27','NSRP'),(29996,61353,'BMP signaling pathway involved in Malpighian tubule cell chemotaxis','P','A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule.','2013-10-27','NSRP'),(29997,61354,'planar cell polarity pathway involved in pericardium morphogenesis','P','The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.','2013-10-27','NSRP'),(29998,61355,'Wnt protein secretion','P','The controlled release of a Wnt protein from a cell.','2013-10-27','NSRP'),(29999,61356,'regulation of Wnt protein secretion','P','Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.','2013-10-27','NSRP'),(30000,61357,'positive regulation of Wnt protein secretion','P','Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.','2013-10-27','NSRP'),(30001,61358,'negative regulation of Wnt protein secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.','2013-10-27','NSRP'),(30002,61359,'regulation of Wnt receptor signaling pathway by Wnt protein secretion','P','Any process that modulates the frequency, rate or extent of the activity of the Wnt receptor mediated signaling pathway by the controlled release of a Wnt protein from a cell.','2013-10-27','NSRP'),(30003,61360,'optic chiasma development','P','The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.','2013-10-27','NSRP'),(30004,61361,'positive regulation of maintenance of bipolar cell polarity regulating cell shape','P','Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.','2013-10-27','NSRP'),(30005,61362,'negative regulation of maintenance of bipolar cell polarity regulating cell shape','P','Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.','2013-10-27','NSRP'),(30006,61363,'negative regulation of progesterone biosynthesis involved in luteolysis','P','Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.','2013-10-27','NSRP'),(30007,61364,'apoptotic process involved in luteolysis','P','The apoptotic process that contributes to luteolysis.','2013-10-27','NSRP'),(30008,61365,'positive regulation of triglyceride lipase activity','P','Any process that increases the activity of triglyceride lipase.','2013-10-27','NSRP'),(30009,61366,'behavioral response to chemical pain','P','Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.','2013-10-27','NSRP'),(30010,61367,'behavioral response to acetic acid induced pain','P','Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.','2013-10-27','NSRP'),(30011,61368,'behavioral response to formalin induced pain','P','Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.','2013-10-27','NSRP'),(30012,61369,'negative regulation of testicular blood vessel morphogenesis','P','Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.','2013-10-27','NSRP'),(30013,61370,'testosterone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.','2013-10-27','NSRP'),(30014,61371,'determination of heart left/right asymmetry','P','Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.','2013-10-27','NSRP'),(30015,61372,'activin receptor signaling pathway involved in heart jogging','P','A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging.','2013-10-27','NSRP'),(30016,61373,'mammillary axonal complex development','P','The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.','2013-10-27','NSRP'),(30017,61374,'mammillothalamic axonal tract development','P','The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.','2013-10-27','NSRP'),(30018,61375,'mammillotectal axonal tract development','P','The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.','2013-10-27','NSRP'),(30019,61376,'mammillotegmental axonal tract development','P','The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.','2013-10-27','NSRP'),(30020,61377,'mammary gland lobule development','P','The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.','2013-10-27','NSRP'),(30021,61378,'corpora quadrigemina development','P','The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.','2013-10-27','NSRP'),(30022,61379,'inferior colliculus development','P','The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.','2013-10-27','NSRP'),(30023,61380,'superior colliculus development','P','The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.','2013-10-27','NSRP'),(30024,61381,'cell migration in diencephalon','P','The orderly movement of a cell that will reside in the diencephalon.','2013-10-27','NSRP'),(30025,61382,'Malpighian tubule tip cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.','2013-10-27','NSRP'),(30026,61383,'trabecula morphogenesis','P','The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.','2013-10-27','NSRP'),(30027,61384,'heart trabecula morphogenesis','P','The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.','2013-10-27','NSRP'),(30028,61385,'fibroblast proliferation involved in heart morphogenesis','P','The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.','2013-10-27','NSRP'),(30029,61386,'closure of optic fissure','P','The closure of the temporary ventral gap in the optic cup that contributes to its shaping.','2013-10-27','NSRP'),(30030,61387,'regulation of extent of cell growth','P','Any process that modulates the extent of cell growth.','2013-10-27','NSRP'),(30031,61388,'regulation of rate of cell growth','P','Any process that modulates the rate of cell growth.','2013-10-27','NSRP'),(30032,61389,'regulation of direction of cell growth','P','Any process that modulates the direction of cell growth.','2013-10-27','NSRP'),(30033,61390,'positive regulation of direction of cell growth','P','Any process that increases the direction of cell growth.','2013-10-27','NSRP'),(30034,61391,'negative regulation of direction of cell growth','P','Any process that decreases the direction of cell growth.','2013-10-27','NSRP'),(30035,65001,'specification of axis polarity','P','The pattern specification process in which the polarity of a body or organ axis is established and maintained.','2013-10-27','NSRP'),(30036,65002,'intracellular protein transmembrane transport','P','The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30037,65003,'macromolecular complex assembly','P','The aggregation, arrangement and bonding together of a set of macromolecules to form a complex.','2013-10-27','NSRP'),(30038,65004,'protein-DNA complex assembly','P','The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.','2013-10-27','NSRP'),(30039,65005,'protein-lipid complex assembly','P','The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.','2013-10-27','NSRP'),(30040,65006,'protein-carbohydrate complex assembly','P','The aggregation, arrangement and bonding together of proteins and carbohydrates to form a protein-carbohydrate complex.','2013-10-27','NSRP'),(30041,65007,'biological regulation','P','Any process that modulates a measurable attribute of any biological process, quality or function.','2013-10-27','NSRP'),(30042,65008,'regulation of biological quality','P','Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.','2013-10-27','NSRP'),(30043,65009,'regulation of molecular function','P','Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.','2013-10-27','NSRP'),(30044,65010,'extracellular membrane-bounded organelle','C','Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.','2013-10-27','NSRP'),(30045,70001,'aspartic-type peptidase activity','F','Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.','2013-10-27','NSRP'),(30046,70002,'glutamic-type peptidase activity','F','Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.','2013-10-27','NSRP'),(30047,70003,'threonine-type peptidase activity','F','Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.','2013-10-27','NSRP'),(30048,70004,'cysteine-type exopeptidase activity','F','Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.','2013-10-27','NSRP'),(30049,70005,'cysteine-type aminopeptidase activity','F','Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.','2013-10-27','NSRP'),(30050,70006,'metalloaminopeptidase activity','F','Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.','2013-10-27','NSRP'),(30051,70007,'glutamic-type endopeptidase activity','F','Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.','2013-10-27','NSRP'),(30052,70008,'serine-type exopeptidase activity','F','Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).','2013-10-27','NSRP'),(30053,70009,'serine-type aminopeptidase activity','F','Catalysis of the hydrolysis of a peptide bond not more than three residues from the N-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).','2013-10-27','NSRP'),(30054,70010,'peptidase activity, acting on D-amino acid peptides','F','Catalysis of the hydrolysis of peptide bonds formed between D-amino acids.','2013-10-27','NSRP'),(30055,70011,'peptidase activity, acting on L-amino acid peptides','F','Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.','2013-10-27','NSRP'),(30056,70012,'oligopeptidase activity','F','Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.','2013-10-27','NSRP'),(30057,70013,'intracellular organelle lumen','C','An organelle lumen that is part of an intracellular organelle.','2013-10-27','NSRP'),(30058,70014,'sucrase-isomaltase complex','C','A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.','2013-10-27','NSRP'),(30059,70016,'armadillo repeat domain binding','F','Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.','2013-10-27','NSRP'),(30060,70017,'alphav-beta3 integrin-thrombospondin complex','C','A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.','2013-10-27','NSRP'),(30061,70018,'transforming growth factor beta type I receptor homodimeric complex','C','A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers.','2013-10-27','NSRP'),(30062,70019,'transforming growth factor beta type II receptor homodimeric complex','C','A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.','2013-10-27','NSRP'),(30063,70020,'transforming growth factor beta1-type II receptor complex','C','A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer.','2013-10-27','NSRP'),(30064,70021,'transforming growth factor beta1-type II receptor-type I receptor complex','C','A protein complex that is formed by the association of a ligand-bound TGF-beta type II receptor dimer with a TGF-beta type I receptor dimer.','2013-10-27','NSRP'),(30065,70022,'transforming growth factor beta receptor homodimeric complex','C','A homodimeric receptor complex that consists of two TGF-beta receptor monomers.','2013-10-27','NSRP'),(30066,70023,'interleukin-12-interleukin-12 receptor complex','C','A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.','2013-10-27','NSRP'),(30067,70024,'CD19-Vav-PIK3R1 complex','C','A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).','2013-10-27','NSRP'),(30068,70025,'carbon monoxide binding','F','Interacting selectively and non-covalently with carbon monoxide (CO).','2013-10-27','NSRP'),(30069,70026,'nitric oxide binding','F','Interacting selectively and non-covalently with nitric oxide (NO).','2013-10-27','NSRP'),(30070,70027,'carbon monoxide sensor activity','F','Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).','2013-10-27','NSRP'),(30071,70028,'regulation of transcription by carbon monoxide','P','Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.','2013-10-27','NSRP'),(30072,70029,'alphav-beta3 integrin-osteopontin complex','C','A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.','2013-10-27','NSRP'),(30073,70030,'alphav-beta1 integrin-osteopontin complex','C','A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.','2013-10-27','NSRP'),(30074,70031,'alphav-beta5 integrin-osteopontin complex','C','A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.','2013-10-27','NSRP'),(30075,70032,'synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).','2013-10-27','NSRP'),(30076,70033,'synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).','2013-10-27','NSRP'),(30077,70034,'telomeric RNA binding','F','Interacting selectively and non-covalently with the telomerase RNA template or to RNA complementary to it.','2013-10-27','NSRP'),(30078,70035,'purine NTP-dependent helicase activity','F','Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.','2013-10-27','NSRP'),(30079,70036,'GTP-dependent helicase activity','F','Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.','2013-10-27','NSRP'),(30080,70037,'rRNA (pseudouridine) methyltransferase activity','F','Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.','2013-10-27','NSRP'),(30081,70038,'rRNA (pseudouridine-N3-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.','2013-10-27','NSRP'),(30082,70039,'rRNA (guanosine-2\'-O-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2\'-O-methylguanosine.','2013-10-27','NSRP'),(30083,70040,'rRNA (adenine-C2-)-methyltransferase activity','F','Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5\'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.','2013-10-27','NSRP'),(30084,70041,'rRNA (uridine-C5-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.','2013-10-27','NSRP'),(30085,70042,'rRNA (uridine-N3-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.','2013-10-27','NSRP'),(30086,70043,'rRNA (guanine-N7-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.','2013-10-27','NSRP'),(30087,70044,'synaptobrevin 2-SNAP-25-syntaxin-1a complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).','2013-10-27','NSRP'),(30088,70045,'synaptobrevin 2-SNAP-25-syntaxin-2 complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).','2013-10-27','NSRP'),(30089,70046,'synaptobrevin 2-SNAP-25-syntaxin-3 complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).','2013-10-27','NSRP'),(30090,70047,'synaptobrevin 2-SNAP-25-syntaxin-4 complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).','2013-10-27','NSRP'),(30091,70048,'endobrevin-SNAP-25-syntaxin-1a complex','C','A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).','2013-10-27','NSRP'),(30092,70049,'endobrevin-SNAP-25-syntaxin-2 complex','C','A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).','2013-10-27','NSRP'),(30093,70050,'neuron cellular homeostasis','P','The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.','2013-10-27','NSRP'),(30094,70051,'fibrinogen binding','F','Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.','2013-10-27','NSRP'),(30095,70052,'collagen V binding','F','Interacting selectively and non-covalently with a type V collagen.','2013-10-27','NSRP'),(30096,70053,'thrombospondin receptor activity','F','Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.','2013-10-27','NSRP'),(30097,70054,'mRNA splicing, via endonucleolytic cleavage and ligation','P','Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5\' and 3\' splice sites into proximity and cleavage of the RNA at both the 3\' and 5\' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.','2013-10-27','NSRP'),(30098,70055,'HAC1-type intron splice site recognition and cleavage','P','The process in which the tertiary structure of a HAC1 type intron is recognized, and the endonucleolytic cleavage of the RNA at both the 5\' and 3\' splice sites occurs.','2013-10-27','NSRP'),(30099,70056,'prospore membrane leading edge','C','The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.','2013-10-27','NSRP'),(30100,70057,'prospore membrane spindle pole body attachment site','C','The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.','2013-10-27','NSRP'),(30101,70058,'tRNA gene clustering','P','The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.','2013-10-27','NSRP'),(30102,70059,'intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress','P','A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.','2013-10-27','NSRP'),(30103,70060,'\'de novo\' actin filament nucleation','P','The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.','2013-10-27','NSRP'),(30104,70061,'fructose binding','F','Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.','2013-10-27','NSRP'),(30105,70062,'extracellular vesicular exosome','C','A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.','2013-10-27','NSRP'),(30106,70063,'RNA polymerase binding','F','Interacting selectively and non-covalently with an RNA polymerase molecule or complex.','2013-10-27','NSRP'),(30107,70064,'proline-rich region binding','F','Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.','2013-10-27','NSRP'),(30108,70065,'cellubrevin-VAMP4-syntaxin-16 complex','C','A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).','2013-10-27','NSRP'),(30109,70066,'cellubrevin-VAMP4-endobrevin-syntaxin-6 complex','C','A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).','2013-10-27','NSRP'),(30110,70067,'syntaxin-6-syntaxin-16-Vti1a complex','C','A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).','2013-10-27','NSRP'),(30111,70068,'VAMP4-syntaxin-6-syntaxin-16-Vti1a complex','C','A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).','2013-10-27','NSRP'),(30112,70069,'cytochrome complex','C','A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.','2013-10-27','NSRP'),(30113,70070,'proton-transporting V-type ATPase complex assembly','P','The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.','2013-10-27','NSRP'),(30114,70071,'proton-transporting two-sector ATPase complex assembly','P','The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.','2013-10-27','NSRP'),(30115,70072,'vacuolar proton-transporting V-type ATPase complex assembly','P','The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.','2013-10-27','NSRP'),(30116,70073,'clustering of voltage-gated calcium channels','P','The process in which voltage-gated calcium channels become localized together in high densities.','2013-10-27','NSRP'),(30117,70074,'mononeme','C','A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.','2013-10-27','NSRP'),(30118,70075,'tear secretion','P','The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.','2013-10-27','NSRP'),(30119,70076,'histone lysine demethylation','P','The modification of a histone by the removal of a methyl group from a lysine residue.','2013-10-27','NSRP'),(30120,70077,'histone arginine demethylation','P','The modification of a histone by the removal of a methyl group from an arginine residue.','2013-10-27','NSRP'),(30121,70078,'histone H3-R2 demethylation','P','The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.','2013-10-27','NSRP'),(30122,70079,'histone H4-R3 demethylation','P','The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.','2013-10-27','NSRP'),(30123,70080,'titin Z domain binding','F','Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.','2013-10-27','NSRP'),(30124,70081,'clathrin-sculpted monoamine transport vesicle','C','A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.','2013-10-27','NSRP'),(30125,70082,'clathrin-sculpted monoamine transport vesicle lumen','C','The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.','2013-10-27','NSRP'),(30126,70083,'clathrin-sculpted monoamine transport vesicle membrane','C','The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.','2013-10-27','NSRP'),(30127,70084,'protein initiator methionine removal','P','The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.','2013-10-27','NSRP'),(30128,70085,'glycosylation','P','The covalent attachment of a glycosyl residue to a substrate molecule.','2013-10-27','NSRP'),(30129,70086,'ubiquitin-dependent endocytosis','P','Endocytosis of a protein that requires the substrate to be modified by uniquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.','2013-10-27','NSRP'),(30130,70087,'chromo shadow domain binding','F','Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.','2013-10-27','NSRP'),(30131,70088,'PHA granule','C','An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.','2013-10-27','NSRP'),(30132,70089,'chloride-activated potassium channel activity','F','Catalysis of the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.','2013-10-27','NSRP'),(30133,70090,'metaphase plate','C','The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.','2013-10-27','NSRP'),(30134,70091,'glucagon secretion','P','The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).','2013-10-27','NSRP'),(30135,70092,'regulation of glucagon secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of glucagon.','2013-10-27','NSRP'),(30136,70093,'negative regulation of glucagon secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.','2013-10-27','NSRP'),(30137,70094,'positive regulation of glucagon secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.','2013-10-27','NSRP'),(30138,70095,'fructose-6-phosphate binding','F','Interacting selectively and non-covalently with fructose 6-phosphate.','2013-10-27','NSRP'),(30139,70096,'mitochondrial outer membrane translocase complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.','2013-10-27','NSRP'),(30140,70097,'delta-catenin binding','F','Interacting selectively and non-covalently with the delta subunit of the catenin complex.','2013-10-27','NSRP'),(30141,70098,'chemokine-mediated signaling pathway','P','A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30142,70099,'regulation of chemokine-mediated signaling pathway','P','Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.','2013-10-27','NSRP'),(30143,70100,'negative regulation of chemokine-mediated signaling pathway','P','Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.','2013-10-27','NSRP'),(30144,70101,'positive regulation of chemokine-mediated signaling pathway','P','Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.','2013-10-27','NSRP'),(30145,70102,'interleukin-6-mediated signaling pathway','P','A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30146,70103,'regulation of interleukin-6-mediated signaling pathway','P','Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor.','2013-10-27','NSRP'),(30147,70104,'negative regulation of interleukin-6-mediated signaling pathway','P','Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.','2013-10-27','NSRP'),(30148,70105,'positive regulation of interleukin-6-mediated signaling pathway','P','Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.','2013-10-27','NSRP'),(30149,70106,'interleukin-27-mediated signaling pathway','P','A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30150,70107,'regulation of interleukin-27-mediated signaling pathway','P','Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor.','2013-10-27','NSRP'),(30151,70108,'negative regulation of interleukin-27-mediated signaling pathway','P','Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.','2013-10-27','NSRP'),(30152,70109,'positive regulation of interleukin-27-mediated signaling pathway','P','Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.','2013-10-27','NSRP'),(30153,70110,'ciliary neurotrophic factor receptor complex','C','A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.','2013-10-27','NSRP'),(30154,70111,'organellar chromatophore','C','A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.','2013-10-27','NSRP'),(30155,70112,'organellar chromatophore membrane','C','Either of the lipid bilayers that surround an organellar chromatophore.','2013-10-27','NSRP'),(30156,70113,'organellar chromatophore inner membrane','C','The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.','2013-10-27','NSRP'),(30157,70114,'organellar chromatophore outer membrane','C','The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.','2013-10-27','NSRP'),(30158,70115,'organellar chromatophore intermembrane space','C','The region between the inner and outer lipid bilayers that surround an organellar chromatophore.','2013-10-27','NSRP'),(30159,70116,'organellar chromatophore thylakoid','C','A thylakoid located in an organellar chromatophore.','2013-10-27','NSRP'),(30160,70117,'organellar chromatophore thylakoid lumen','C','The volume enclosed by an organellar chromatophore thylakoid membrane.','2013-10-27','NSRP'),(30161,70118,'organellar chromatophore thylakoid membrane','C','The lipid bilayer membrane of any thylakoid within an organellar chromatophore.','2013-10-27','NSRP'),(30162,70119,'ciliary neurotrophic factor binding','F','Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor.','2013-10-27','NSRP'),(30163,70120,'ciliary neurotrophic factor-mediated signaling pathway','P','A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30164,70121,'Kupffer\'s vesicle development','P','The progression of the Kupffer\'s vesicle over time from its initial formation until its mature state. The Kupffer\'s vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.','2013-10-27','NSRP'),(30165,70122,'isopeptidase activity','F','Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond).','2013-10-27','NSRP'),(30166,70123,'transforming growth factor beta receptor activity, type III','F','Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.','2013-10-27','NSRP'),(30167,70124,'mitochondrial translational initiation','P','The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.','2013-10-27','NSRP'),(30168,70125,'mitochondrial translational elongation','P','The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.','2013-10-27','NSRP'),(30169,70126,'mitochondrial translational termination','P','The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).','2013-10-27','NSRP'),(30170,70127,'tRNA aminoacylation for mitochondrial protein translation','P','The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3\'-hydroxyl group of the most 3\' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.','2013-10-27','NSRP'),(30171,70129,'regulation of mitochondrial translation','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.','2013-10-27','NSRP'),(30172,70130,'negative regulation of mitochondrial translation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.','2013-10-27','NSRP'),(30173,70131,'positive regulation of mitochondrial translation','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.','2013-10-27','NSRP'),(30174,70132,'regulation of mitochondrial translational initiation','P','Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.','2013-10-27','NSRP'),(30175,70133,'negative regulation of mitochondrial translational initiation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.','2013-10-27','NSRP'),(30176,70134,'positive regulation of mitochondrial translational initiation','P','Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.','2013-10-27','NSRP'),(30177,70135,'beta-1,2-oligomannoside metabolic process','P','The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.','2013-10-27','NSRP'),(30178,70136,'beta-1,2-oligomannoside biosynthetic process','P','The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.','2013-10-27','NSRP'),(30179,70137,'small conjugating protein-specific endopeptidase activity','F','Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).','2013-10-27','NSRP'),(30180,70138,'small conjugating protein-specific isopeptidase activity','F','Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated.','2013-10-27','NSRP'),(30181,70139,'SUMO-specific endopeptidase activity','F','Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.','2013-10-27','NSRP'),(30182,70140,'SUMO-specific isopeptidase activity','F','Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.','2013-10-27','NSRP'),(30183,70141,'response to UV-A','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 400 to 500 nm.','2013-10-27','NSRP'),(30184,70142,'synaptic vesicle budding','P','Evagination of a membrane to form a synaptic vesicle.','2013-10-27','NSRP'),(30185,70143,'mitochondrial alanyl-tRNA aminoacylation','P','The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30186,70144,'mitochondrial arginyl-tRNA aminoacylation','P','The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30187,70145,'mitochondrial asparaginyl-tRNA aminoacylation','P','The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30188,70146,'mitochondrial aspartyl-tRNA aminoacylation','P','The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30189,70147,'mitochondrial cysteinyl-tRNA aminoacylation','P','The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30190,70148,'mitochondrial glutaminyl-tRNA aminoacylation','P','The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30191,70149,'mitochondrial glutamyl-tRNA aminoacylation','P','The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30192,70150,'mitochondrial glycyl-tRNA aminoacylation','P','The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30193,70151,'mitochondrial histidyl-tRNA aminoacylation','P','The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30194,70152,'mitochondrial isoleucyl-tRNA aminoacylation','P','The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30195,70153,'mitochondrial leucyl-tRNA aminoacylation','P','The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30196,70154,'mitochondrial lysyl-tRNA aminoacylation','P','The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30197,70155,'mitochondrial methionyl-tRNA aminoacylation','P','The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30198,70156,'mitochondrial phenylalanyl-tRNA aminoacylation','P','The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30199,70157,'mitochondrial prolyl-tRNA aminoacylation','P','The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30200,70158,'mitochondrial seryl-tRNA aminoacylation','P','The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30201,70159,'mitochondrial threonyl-tRNA aminoacylation','P','The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30202,70160,'occluding junction','C','A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.','2013-10-27','NSRP'),(30203,70161,'anchoring junction','C','A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.','2013-10-27','NSRP'),(30204,70162,'adiponectin secretion','P','The regulated release of adiponectin, a protein hormone, by adipose tissue.','2013-10-27','NSRP'),(30205,70163,'regulation of adiponectin secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.','2013-10-27','NSRP'),(30206,70164,'negative regulation of adiponectin secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.','2013-10-27','NSRP'),(30207,70165,'positive regulation of adiponectin secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.','2013-10-27','NSRP'),(30208,70166,'enamel mineralization','P','The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.','2013-10-27','NSRP'),(30209,70167,'regulation of biomineral tissue development','P','Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.','2013-10-27','NSRP'),(30210,70168,'negative regulation of biomineral tissue development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.','2013-10-27','NSRP'),(30211,70169,'positive regulation of biomineral tissue development','P','Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.','2013-10-27','NSRP'),(30212,70170,'regulation of tooth mineralization','P','Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.','2013-10-27','NSRP'),(30213,70171,'negative regulation of tooth mineralization','P','Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.','2013-10-27','NSRP'),(30214,70172,'positive regulation of tooth mineralization','P','Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.','2013-10-27','NSRP'),(30215,70173,'regulation of enamel mineralization','P','Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.','2013-10-27','NSRP'),(30216,70174,'negative regulation of enamel mineralization','P','Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.','2013-10-27','NSRP'),(30217,70175,'positive regulation of enamel mineralization','P','Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.','2013-10-27','NSRP'),(30218,70176,'DRM complex','C','A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.','2013-10-27','NSRP'),(30219,70177,'contractile vacuole discharge','P','The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.','2013-10-27','NSRP'),(30220,70178,'D-serine metabolic process','P','The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.','2013-10-27','NSRP'),(30221,70179,'D-serine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.','2013-10-27','NSRP'),(30222,70180,'LSU rRNA binding','F','Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.','2013-10-27','NSRP'),(30223,70181,'SSU rRNA binding','F','Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.','2013-10-27','NSRP'),(30224,70182,'DNA polymerase binding','F','Interacting selectively and non-covalently with a DNA polymerase.','2013-10-27','NSRP'),(30225,70183,'mitochondrial tryptophanyl-tRNA aminoacylation','P','The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30226,70184,'mitochondrial tyrosyl-tRNA aminoacylation','P','The process of coupling threonine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30227,70185,'mitochondrial valyl-tRNA aminoacylation','P','The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2\'- or the 3\'-hydroxyl group of the 3\'-adenosine residue of the tRNA.','2013-10-27','NSRP'),(30228,70186,'growth hormone activity','F','The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.','2013-10-27','NSRP'),(30229,70187,'telosome','C','A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex contains TRF1, TRF2, POT1, RAP1, TIN2 and TPP1 in mammalian cells, and Pot1, Tpz1, Ccq1, Poz1, and Rap1 in Schizosaccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1.','2013-10-27','NSRP'),(30230,70188,'Stn1-Ten1 complex','C','A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present.','2013-10-27','NSRP'),(30231,70189,'kynurenine metabolic process','P','The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.','2013-10-27','NSRP'),(30232,70190,'inositol hexakisphosphate 1-kinase or 3-kinase activity','F','OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.','2013-10-27','NSRP'),(30233,70191,'methionine-R-sulfoxide reductase activity','F','Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.','2013-10-27','NSRP'),(30234,70192,'chromosome organization involved in meiosis','P','A process of chromosome organization that is involved in meiosis.','2013-10-27','NSRP'),(30235,70193,'synaptonemal complex organization','P','A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.','2013-10-27','NSRP'),(30236,70194,'synaptonemal complex disassembly','P','The controlled breakdown of a synaptonemal complex.','2013-10-27','NSRP'),(30237,70195,'growth hormone receptor complex','C','A receptor complex that consists of two identical subunits and binds growth hormone.','2013-10-27','NSRP'),(30238,70196,'eukaryotic translation initiation factor 3 complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.','2013-10-27','NSRP'),(30239,70197,'attachment of telomeric heterochromatin to nuclear envelope','P','The cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.','2013-10-27','NSRP'),(30240,70198,'protein localization to chromosome, telomeric region','P','Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.','2013-10-27','NSRP'),(30241,70199,'establishment of protein localization to chromosome','P','The directed movement of a protein to a specific location on a chromosome.','2013-10-27','NSRP'),(30242,70200,'establishment of protein localization to telomere','P','The directed movement of a protein to a specific location in the telomeric region of a chromosome.','2013-10-27','NSRP'),(30243,70201,'regulation of establishment of protein localization','P','Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.','2013-10-27','NSRP'),(30244,70202,'regulation of establishment of protein localization to chromosome','P','Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.','2013-10-27','NSRP'),(30245,70203,'regulation of establishment of protein localization to telomere','P','Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.','2013-10-27','NSRP'),(30246,70204,'2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity','F','Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).','2013-10-27','NSRP'),(30247,70205,'2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity','F','Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.','2013-10-27','NSRP'),(30248,70206,'protein trimerization','P','The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.','2013-10-27','NSRP'),(30249,70207,'protein homotrimerization','P','The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.','2013-10-27','NSRP'),(30250,70208,'protein heterotrimerization','P','The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.','2013-10-27','NSRP'),(30251,70209,'ASTRA complex','C','A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.','2013-10-27','NSRP'),(30252,70210,'Rpd3L-Expanded complex','C','A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.','2013-10-27','NSRP'),(30253,70211,'Snt2C complex','C','A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.','2013-10-27','NSRP'),(30254,70212,'protein poly-ADP-ribosylation','P','The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.','2013-10-27','NSRP'),(30255,70213,'protein auto-ADP-ribosylation','P','The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.','2013-10-27','NSRP'),(30256,70214,'CSK-GAP-A.p62 complex','C','A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.','2013-10-27','NSRP'),(30257,70215,'MDM2 binding','F','OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM2 protein, a negative regulator of p53.','2013-10-27','NSRP'),(30258,70216,'MDM4 binding','F','OBSOLETE. Interacting selectively and non-covalently with any isoform of the MDM4 protein, a negative regulator of p53.','2013-10-27','NSRP'),(30259,70217,'transcription factor TFIIIB complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.','2013-10-27','NSRP'),(30260,70218,'sulfide ion homeostasis','P','Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.','2013-10-27','NSRP'),(30261,70219,'cellular sulfide ion homeostasis','P','Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.','2013-10-27','NSRP'),(30262,70220,'aerobic sulfur oxidation','P','A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.','2013-10-27','NSRP'),(30263,70221,'sulfide oxidation, using sulfide:quinone oxidoreductase','P','A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.','2013-10-27','NSRP'),(30264,70222,'sulfide oxidation, using sulfide dehydrogenase','P','A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.','2013-10-27','NSRP'),(30265,70223,'sulfide oxidation, using sulfur dioxygenase','P','A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.','2013-10-27','NSRP'),(30266,70224,'sulfide:quinone oxidoreductase activity','F','Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone.','2013-10-27','NSRP'),(30267,70225,'sulfide dehydrogenase activity','F','Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c.','2013-10-27','NSRP'),(30268,70226,'sulfur:ferric ion oxidoreductase activity','F','Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.','2013-10-27','NSRP'),(30269,70227,'lymphocyte apoptotic process','P','Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.','2013-10-27','NSRP'),(30270,70228,'regulation of lymphocyte apoptotic process','P','Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.','2013-10-27','NSRP'),(30271,70229,'negative regulation of lymphocyte apoptotic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.','2013-10-27','NSRP'),(30272,70230,'positive regulation of lymphocyte apoptotic process','P','Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.','2013-10-27','NSRP'),(30273,70231,'T cell apoptotic process','P','Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.','2013-10-27','NSRP'),(30274,70232,'regulation of T cell apoptotic process','P','Any process that modulates the occurrence or rate of T cell death by apoptotic process.','2013-10-27','NSRP'),(30275,70233,'negative regulation of T cell apoptotic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.','2013-10-27','NSRP'),(30276,70234,'positive regulation of T cell apoptotic process','P','Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.','2013-10-27','NSRP'),(30277,70235,'regulation of activation-induced cell death of T cells','P','Any process that modulates the occurrence or rate of activation-induced cell death of T cells.','2013-10-27','NSRP'),(30278,70236,'negative regulation of activation-induced cell death of T cells','P','Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.','2013-10-27','NSRP'),(30279,70237,'positive regulation of activation-induced cell death of T cells','P','Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.','2013-10-27','NSRP'),(30280,70238,'activated T cell autonomous cell death','P','A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.','2013-10-27','NSRP'),(30281,70239,'regulation of activated T cell autonomous cell death','P','Any process that modulates the occurrence or rate of activated T cell autonomous cell death.','2013-10-27','NSRP'),(30282,70240,'negative regulation of activated T cell autonomous cell death','P','Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.','2013-10-27','NSRP'),(30283,70241,'positive regulation of activated T cell autonomous cell death','P','Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.','2013-10-27','NSRP'),(30284,70242,'thymocyte apoptotic process','P','Any apoptotic process in a thymocyte, an immature T cell located in the thymus.','2013-10-27','NSRP'),(30285,70243,'regulation of thymocyte apoptotic process','P','Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.','2013-10-27','NSRP'),(30286,70244,'negative regulation of thymocyte apoptotic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.','2013-10-27','NSRP'),(30287,70245,'positive regulation of thymocyte apoptotic process','P','Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.','2013-10-27','NSRP'),(30288,70246,'natural killer cell apoptotic process','P','Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.','2013-10-27','NSRP'),(30289,70247,'regulation of natural killer cell apoptotic process','P','Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.','2013-10-27','NSRP'),(30290,70248,'negative regulation of natural killer cell apoptotic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.','2013-10-27','NSRP'),(30291,70249,'positive regulation of natural killer cell apoptotic process','P','Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.','2013-10-27','NSRP'),(30292,70250,'mating projection membrane','C','The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.','2013-10-27','NSRP'),(30293,70251,'pristanate-CoA ligase activity','F','Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.','2013-10-27','NSRP'),(30294,70252,'actin-mediated cell contraction','P','The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.','2013-10-27','NSRP'),(30295,70253,'somatostatin secretion','P','The regulated release of somatostatin from secretory granules in the D cells of the pancreas.','2013-10-27','NSRP'),(30296,70254,'mucus secretion','P','The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.','2013-10-27','NSRP'),(30297,70255,'regulation of mucus secretion','P','Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.','2013-10-27','NSRP'),(30298,70256,'negative regulation of mucus secretion','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.','2013-10-27','NSRP'),(30299,70257,'positive regulation of mucus secretion','P','Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.','2013-10-27','NSRP'),(30300,70258,'inner membrane complex','C','A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.','2013-10-27','NSRP'),(30301,70259,'tyrosyl-DNA phosphodiesterase activity','F','Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.','2013-10-27','NSRP'),(30302,70260,'5\'-tyrosyl-DNA phosphodiesterase activity','F','Catalysis of the hydrolysis of 5\'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.','2013-10-27','NSRP'),(30303,70262,'peptidyl-serine dephosphorylation','P','The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.','2013-10-27','NSRP'),(30304,70263,'external side of fungal-type cell wall','C','The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.','2013-10-27','NSRP'),(30305,70264,'transcription factor TFIIIE complex','C','A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.','2013-10-27','NSRP'),(30306,70265,'necrotic cell death','P','A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.','2013-10-27','NSRP'),(30307,70266,'necroptosis','P','A type of programmed necrotic cell death characterized by activation of receptor interaction protein kinase 1 and/or 3 (RIP1 and/or RIP3).','2013-10-27','NSRP'),(30308,70267,'oncosis','P','A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death.','2013-10-27','NSRP'),(30309,70268,'cornification','P','A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).','2013-10-27','NSRP'),(30310,70269,'pyroptosis','P','A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.','2013-10-27','NSRP'),(30311,70270,'mitotic catastrophe','P','OBSOLETE. A type of programmed cell death that occurs during or shortly after a dysregulated or failed mitosis and can be accompanied by morphological alterations including micronucleation and multinucleation.','2013-10-27','NSRP'),(30312,70271,'protein complex biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex.','2013-10-27','NSRP'),(30313,70272,'proton-transporting ATP synthase complex biogenesis','P','The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.','2013-10-27','NSRP'),(30314,70273,'phosphatidylinositol-4-phosphate binding','F','Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4\' position.','2013-10-27','NSRP'),(30315,70274,'RES complex','C','A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.','2013-10-27','NSRP'),(30316,70275,'aerobic ammonia oxidation to nitrite via pyruvic oxime','P','The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.','2013-10-27','NSRP'),(30317,70276,'halogen metabolic process','P','The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.','2013-10-27','NSRP'),(30318,70277,'iodide oxidation','P','The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.','2013-10-27','NSRP'),(30319,70278,'extracellular matrix constituent secretion','P','The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.','2013-10-27','NSRP'),(30320,70279,'vitamin B6 binding','F','Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.','2013-10-27','NSRP'),(30321,70280,'pyridoxal binding','F','Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.','2013-10-27','NSRP'),(30322,70281,'pyridoxamine binding','F','Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.','2013-10-27','NSRP'),(30323,70282,'pyridoxine binding','F','Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.','2013-10-27','NSRP'),(30324,70283,'radical SAM enzyme activity','F','Catalysis of a reaction in which S-adenosyl-L-methionine (SAM) undergoes reductive cleavage to serve as a source of the 5\'-deoxyadenosyl radical.','2013-10-27','NSRP'),(30325,70284,'4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity','F','Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5\'deoxyadenosine.','2013-10-27','NSRP'),(30326,70285,'pigment cell development','P','The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.','2013-10-27','NSRP'),(30327,70286,'axonemal dynein complex assembly','P','The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.','2013-10-27','NSRP'),(30328,70287,'ferritin receptor activity','F','Combining with ferritin, and delivering ferritin into the cell via endocytosis.','2013-10-27','NSRP'),(30329,70288,'ferritin complex','C','A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.','2013-10-27','NSRP'),(30330,70289,'extracellular ferritin complex','C','A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.','2013-10-27','NSRP'),(30331,70290,'NAPE-specific phospholipase D activity','F','Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).','2013-10-27','NSRP'),(30332,70291,'N-acylethanolamine metabolic process','P','The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.','2013-10-27','NSRP'),(30333,70292,'N-acylphosphatidylethanolamine metabolic process','P','The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.','2013-10-27','NSRP'),(30334,70293,'renal absorption','P','A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.','2013-10-27','NSRP'),(30335,70294,'renal sodium ion absorption','P','A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron.','2013-10-27','NSRP'),(30336,70295,'renal water absorption','P','A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron.','2013-10-27','NSRP'),(30337,70296,'sarcoplasmic reticulum calcium ion transport','P','The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.','2013-10-27','NSRP'),(30338,70297,'regulation of phosphorelay signal transduction system','P','Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.','2013-10-27','NSRP'),(30339,70298,'negative regulation of phosphorelay signal transduction system','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.','2013-10-27','NSRP'),(30340,70299,'positive regulation of phosphorelay signal transduction system','P','Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.','2013-10-27','NSRP'),(30341,70300,'phosphatidic acid binding','F','Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.','2013-10-27','NSRP'),(30342,70301,'cellular response to hydrogen peroxide','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.','2013-10-27','NSRP'),(30343,70302,'regulation of stress-activated protein kinase signaling cascade','P','Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.','2013-10-27','NSRP'),(30344,70303,'negative regulation of stress-activated protein kinase signaling cascade','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.','2013-10-27','NSRP'),(30345,70304,'positive regulation of stress-activated protein kinase signaling cascade','P','Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.','2013-10-27','NSRP'),(30346,70305,'response to cGMP','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3\',5\'-cyclophosphate) stimulus.','2013-10-27','NSRP'),(30347,70306,'lens fiber cell differentiation','P','The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.','2013-10-27','NSRP'),(30348,70307,'lens fiber cell development','P','The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.','2013-10-27','NSRP'),(30349,70308,'lens fiber cell fate commitment','P','The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.','2013-10-27','NSRP'),(30350,70309,'lens fiber cell morphogenesis','P','The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.','2013-10-27','NSRP'),(30351,70310,'ATR-ATRIP complex','C','A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.','2013-10-27','NSRP'),(30352,70311,'nucleosomal methylation activator complex','C','A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.','2013-10-27','NSRP'),(30353,70312,'RAD52-ERCC4-ERCC1 complex','C','A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.','2013-10-27','NSRP'),(30354,70313,'RGS6-DNMT1-DMAP1 complex','C','A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.','2013-10-27','NSRP'),(30355,70314,'G1 to G0 transition','P','A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.','2013-10-27','NSRP'),(30356,70315,'G1 to G0 transition involved in cell differentiation','P','A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.','2013-10-27','NSRP'),(30357,70316,'regulation of G0 to G1 transition','P','A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.','2013-10-27','NSRP'),(30358,70317,'negative regulation of G0 to G1 transition','P','A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.','2013-10-27','NSRP'),(30359,70318,'positive regulation of G0 to G1 transition','P','A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.','2013-10-27','NSRP'),(30360,70319,'Golgi to plasma membrane transport vesicle','C','A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.','2013-10-27','NSRP'),(30361,70320,'inward rectifier potassium channel inhibitor activity','F','Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.','2013-10-27','NSRP'),(30362,70321,'regulation of translation in response to nitrogen starvation','P','Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.','2013-10-27','NSRP'),(30363,70322,'negative regulation of translation in response to nitrogen starvation','P','Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen.','2013-10-27','NSRP'),(30364,70323,'positive regulation of translation in response to nitrogen starvation','P','Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.','2013-10-27','NSRP'),(30365,70324,'thyroid hormone binding','F','Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.','2013-10-27','NSRP'),(30366,70325,'lipoprotein particle receptor binding','F','Interacting selectively and non-covalently with a lipoprotein particle receptor.','2013-10-27','NSRP'),(30367,70326,'very-low-density lipoprotein particle receptor binding','F','Interacting selectively and non-covalently with a very-low-density lipoprotein receptor.','2013-10-27','NSRP'),(30368,70327,'thyroid hormone transport','P','The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30369,70328,'triglyceride homeostasis','P','Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.','2013-10-27','NSRP'),(30370,70329,'tRNA seleno-modification','P','The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.','2013-10-27','NSRP'),(30371,70330,'aromatase activity','F','Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.','2013-10-27','NSRP'),(30372,70331,'CD20-Lck-Fyn complex','C','A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.','2013-10-27','NSRP'),(30373,70332,'CD20-Lck-Lyn-Fyn complex','C','A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.','2013-10-27','NSRP'),(30374,70333,'alpha6-beta4 integrin-Shc-Grb2 complex','C','A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.','2013-10-27','NSRP'),(30375,70334,'alpha6-beta4 integrin-laminin 5 complex','C','A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.','2013-10-27','NSRP'),(30376,70335,'aspartate binding','F','Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.','2013-10-27','NSRP'),(30377,70336,'flap-structured DNA binding','F','Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.','2013-10-27','NSRP'),(30378,70337,'3\'-flap-structured DNA binding','F','Interacting selectively and non-covalently with a 3\'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3\'-end of DNA or RNA protrudes from a double-stranded DNA molecule.','2013-10-27','NSRP'),(30379,70338,'5\'-flap-structured DNA binding','F','Interacting selectively and non-covalently with a 5\'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5\'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5\'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.','2013-10-27','NSRP'),(30380,70339,'response to bacterial lipopeptide','P','Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.','2013-10-27','NSRP'),(30381,70340,'detection of bacterial lipopeptide','P','The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.','2013-10-27','NSRP'),(30382,70341,'fat cell proliferation','P','The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.','2013-10-27','NSRP'),(30383,70342,'brown fat cell proliferation','P','The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.','2013-10-27','NSRP'),(30384,70343,'white fat cell proliferation','P','The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.','2013-10-27','NSRP'),(30385,70344,'regulation of fat cell proliferation','P','Any process that modulates the frequency, rate or extent of fat cell proliferation.','2013-10-27','NSRP'),(30386,70345,'negative regulation of fat cell proliferation','P','Any process that stops or decreases the rate or extent of fat cell proliferation.','2013-10-27','NSRP'),(30387,70346,'positive regulation of fat cell proliferation','P','Any process that activates or increases the rate or extent of fat cell proliferation.','2013-10-27','NSRP'),(30388,70347,'regulation of brown fat cell proliferation','P','Any process that modulates the frequency, rate or extent of brown fat cell proliferation.','2013-10-27','NSRP'),(30389,70348,'negative regulation of brown fat cell proliferation','P','Any process that stops or decreases the rate or extent of brown fat cell proliferation.','2013-10-27','NSRP'),(30390,70349,'positive regulation of brown fat cell proliferation','P','Any process that activates or increases the rate or extent of brown fat cell proliferation.','2013-10-27','NSRP'),(30391,70350,'regulation of white fat cell proliferation','P','Any process that modulates the frequency, rate or extent of white fat cell proliferation.','2013-10-27','NSRP'),(30392,70351,'negative regulation of white fat cell proliferation','P','Any process that stops or decreases the rate or extent of white fat cell proliferation.','2013-10-27','NSRP'),(30393,70352,'positive regulation of white fat cell proliferation','P','Any process that activates or increases the rate or extent of white fat cell proliferation.','2013-10-27','NSRP'),(30394,70353,'GATA1-TAL1-TCF3-Lmo2 complex','C','A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.','2013-10-27','NSRP'),(30395,70354,'GATA2-TAL1-TCF3-Lmo2 complex','C','A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.','2013-10-27','NSRP'),(30396,70355,'synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex','C','A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).','2013-10-27','NSRP'),(30397,70356,'synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex','C','A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).','2013-10-27','NSRP'),(30398,70357,'alphav-beta3 integrin-CD47 complex','C','A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).','2013-10-27','NSRP'),(30399,70358,'actin polymerization-dependent cell motility','P','A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.','2013-10-27','NSRP'),(30400,70359,'actin polymerization-dependent cell motility involved in migration of symbiont in host','P','A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell.','2013-10-27','NSRP'),(30401,70360,'migration of symbiont within host by polymerization of host actin','P','The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.','2013-10-27','NSRP'),(30402,70361,'mitochondrial light strand promoter anti-sense binding','F','Interacting selectively and non-covalently with the anti-sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA.','2013-10-27','NSRP'),(30403,70362,'mitochondrial heavy strand promoter anti-sense binding','F','Interacting selectively and non-covalently with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.','2013-10-27','NSRP'),(30404,70363,'mitochondrial light strand promoter sense binding','F','Interacting selectively and non-covalently with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA.','2013-10-27','NSRP'),(30405,70364,'mitochondrial heavy strand promoter sense binding','F','Interacting selectively and non-covalently with the sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.','2013-10-27','NSRP'),(30406,70365,'hepatocyte differentiation','P','The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.','2013-10-27','NSRP'),(30407,70366,'regulation of hepatocyte differentiation','P','Any process that modulates the frequency, rate or extent of hepatocyte differentiation.','2013-10-27','NSRP'),(30408,70367,'negative regulation of hepatocyte differentiation','P','Any process that stops or decreases the rate or extent of hepatocyte differentiation.','2013-10-27','NSRP'),(30409,70368,'positive regulation of hepatocyte differentiation','P','Any process that activates or increases the rate or extent of hepatocyte differentiation.','2013-10-27','NSRP'),(30410,70369,'beta-catenin-TCF7L2 complex','C','A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.','2013-10-27','NSRP'),(30411,70370,'cellular heat acclimation','P','Any process that increases heat tolerance of a cell in response to high temperatures.','2013-10-27','NSRP'),(30412,70371,'ERK1 and ERK2 cascade','P','An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.','2013-10-27','NSRP'),(30413,70372,'regulation of ERK1 and ERK2 cascade','P','Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.','2013-10-27','NSRP'),(30414,70373,'negative regulation of ERK1 and ERK2 cascade','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.','2013-10-27','NSRP'),(30415,70374,'positive regulation of ERK1 and ERK2 cascade','P','Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.','2013-10-27','NSRP'),(30416,70375,'ERK5 cascade','P','An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.','2013-10-27','NSRP'),(30417,70376,'regulation of ERK5 cascade','P','Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.','2013-10-27','NSRP'),(30418,70377,'negative regulation of ERK5 cascade','P','Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.','2013-10-27','NSRP'),(30419,70378,'positive regulation of ERK5 cascade','P','Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.','2013-10-27','NSRP'),(30420,70379,'high mobility group box 1 binding','F','Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1).','2013-10-27','NSRP'),(30421,70380,'high mobility group box 1 receptor activity','F','Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(30422,70381,'endosome to plasma membrane transport vesicle','C','A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.','2013-10-27','NSRP'),(30423,70382,'exocytic vesicle','C','A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.','2013-10-27','NSRP'),(30424,70383,'DNA cytosine deamination','P','The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.','2013-10-27','NSRP'),(30425,70384,'Harderian gland development','P','The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.','2013-10-27','NSRP'),(30426,70385,'egasyn-beta-glucuronidase complex','C','A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.','2013-10-27','NSRP'),(30427,70386,'procollagen-proline 4-dioxygenase complex, alpha(I) type','C','A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).','2013-10-27','NSRP'),(30428,70387,'procollagen-proline 4-dioxygenase complex, alpha(II) type','C','A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.','2013-10-27','NSRP'),(30429,70388,'procollagen-proline 4-dioxygenase complex, alpha(III) type','C','A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.','2013-10-27','NSRP'),(30430,70389,'chaperone cofactor-dependent protein refolding','P','The process of assisting in the restoration of the biological activity of an unfolded or misfolded protein, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.','2013-10-27','NSRP'),(30431,70390,'transcription export complex 2','C','A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sus1p and Cdc31p.','2013-10-27','NSRP'),(30432,70391,'response to lipoteichoic acid','P','Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.','2013-10-27','NSRP'),(30433,70392,'detection of lipoteichoic acid','P','The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.','2013-10-27','NSRP'),(30434,70393,'teichoic acid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.','2013-10-27','NSRP'),(30435,70394,'lipoteichoic acid metabolic process','P','The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.','2013-10-27','NSRP'),(30436,70395,'lipoteichoic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.','2013-10-27','NSRP'),(30437,70396,'lipoteichoic acid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.','2013-10-27','NSRP'),(30438,70397,'wall teichoic acid metabolic process','P','The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.','2013-10-27','NSRP'),(30439,70398,'wall teichoic acid biosynthetic process','P','The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.','2013-10-27','NSRP'),(30440,70399,'wall teichoic acid catabolic process','P','The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.','2013-10-27','NSRP'),(30441,70400,'teichoic acid D-alanylation','P','The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.','2013-10-27','NSRP'),(30442,70401,'NADP+ binding','F','Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.','2013-10-27','NSRP'),(30443,70402,'NADPH binding','F','Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.','2013-10-27','NSRP'),(30444,70403,'NAD+ binding','F','Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.','2013-10-27','NSRP'),(30445,70404,'NADH binding','F','Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.','2013-10-27','NSRP'),(30446,70405,'ammonium ion binding','F','Interacting selectively and non-covalently with ammonium ions (NH4+).','2013-10-27','NSRP'),(30447,70406,'glutamine binding','F','Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid.','2013-10-27','NSRP'),(30448,70407,'oxidation-dependent protein catabolic process','P','The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.','2013-10-27','NSRP'),(30449,70408,'carbamoyl phosphate metabolic process','P','The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.','2013-10-27','NSRP'),(30450,70409,'carbamoyl phosphate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.','2013-10-27','NSRP'),(30451,70410,'co-SMAD binding','F','Interacting selectively and non-covalently with a common mediator SMAD signaling protein.','2013-10-27','NSRP'),(30452,70411,'I-SMAD binding','F','Interacting selectively and non-covalently with an inhibitory SMAD signaling protein.','2013-10-27','NSRP'),(30453,70412,'R-SMAD binding','F','Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.','2013-10-27','NSRP'),(30454,70413,'trehalose metabolism in response to stress','P','The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.','2013-10-27','NSRP'),(30455,70414,'trehalose metabolism in response to heat stress','P','The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.','2013-10-27','NSRP'),(30456,70415,'trehalose metabolism in response to cold stress','P','The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.','2013-10-27','NSRP'),(30457,70416,'trehalose metabolism in response to water deprivation','P','The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.','2013-10-27','NSRP'),(30458,70417,'cellular response to cold','P','Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.','2013-10-27','NSRP'),(30459,70418,'DNA-dependent protein kinase complex','C','A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.','2013-10-27','NSRP'),(30460,70419,'nonhomologous end joining complex','C','A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.','2013-10-27','NSRP'),(30461,70420,'Ku-DNA ligase complex','C','A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.','2013-10-27','NSRP'),(30462,70421,'DNA ligase III-XRCC1 complex','C','A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.','2013-10-27','NSRP'),(30463,70422,'G-protein beta/gamma-Raf-1 complex','C','A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.','2013-10-27','NSRP'),(30464,70423,'nucleotide-binding oligomerization domain containing signaling pathway','P','Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.','2013-10-27','NSRP'),(30465,70424,'regulation of nucleotide-binding oligomerization domain containing signaling pathway','P','Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.','2013-10-27','NSRP'),(30466,70425,'negative regulation of nucleotide-binding oligomerization domain containing signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.','2013-10-27','NSRP'),(30467,70426,'positive regulation of nucleotide-binding oligomerization domain containing signaling pathway','P','Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.','2013-10-27','NSRP'),(30468,70427,'nucleotide-binding oligomerization domain containing 1 signaling pathway','P','Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).','2013-10-27','NSRP'),(30469,70428,'regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway','P','Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.','2013-10-27','NSRP'),(30470,70429,'negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.','2013-10-27','NSRP'),(30471,70430,'positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway','P','Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.','2013-10-27','NSRP'),(30472,70431,'nucleotide-binding oligomerization domain containing 2 signaling pathway','P','Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).','2013-10-27','NSRP'),(30473,70432,'regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway','P','Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.','2013-10-27','NSRP'),(30474,70433,'negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.','2013-10-27','NSRP'),(30475,70434,'positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway','P','Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.','2013-10-27','NSRP'),(30476,70435,'Shc-EGFR complex','C','A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30477,70436,'Grb2-EGFR complex','C','A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30478,70437,'Grb2-Shc complex','C','A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30479,70438,'mTOR-FKBP12-rapamycin complex','C','A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).','2013-10-27','NSRP'),(30480,70439,'Mad-Max-mSin3A complex','C','A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.','2013-10-27','NSRP'),(30481,70440,'Mad-Max-mSin3B complex','C','A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.','2013-10-27','NSRP'),(30482,70441,'G-protein beta/gamma-Btk complex','C','A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.','2013-10-27','NSRP'),(30483,70442,'alphaIIb-beta3 integrin complex','C','An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.','2013-10-27','NSRP'),(30484,70443,'Mad-Max complex','C','A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.','2013-10-27','NSRP'),(30485,70444,'oligodendrocyte progenitor proliferation','P','The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.','2013-10-27','NSRP'),(30486,70445,'regulation of oligodendrocyte progenitor proliferation','P','Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.','2013-10-27','NSRP'),(30487,70446,'negative regulation of oligodendrocyte progenitor proliferation','P','Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.','2013-10-27','NSRP'),(30488,70447,'positive regulation of oligodendrocyte progenitor proliferation','P','Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.','2013-10-27','NSRP'),(30489,70448,'laricitrin 5\'-O-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.','2013-10-27','NSRP'),(30490,70449,'elongin complex','C','A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3\'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (abut 100 kDa)and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa)subunits.','2013-10-27','NSRP'),(30491,70450,'interleukin4-interleukin-4 receptor complex','C','A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.','2013-10-27','NSRP'),(30492,70451,'cell hair','C','A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.','2013-10-27','NSRP'),(30493,70452,'positive regulation of ergosterol biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.','2013-10-27','NSRP'),(30494,70453,'regulation of heme biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.','2013-10-27','NSRP'),(30495,70454,'negative regulation of heme biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.','2013-10-27','NSRP'),(30496,70455,'positive regulation of heme biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.','2013-10-27','NSRP'),(30497,70456,'galactose-1-phosphate phosphatase activity','F','Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.','2013-10-27','NSRP'),(30498,70457,'D-galactose-1-phosphate phosphatase activity','F','Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.','2013-10-27','NSRP'),(30499,70458,'cellular detoxification of nitrogen compound','P','Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.','2013-10-27','NSRP'),(30500,70459,'prolactin secretion','P','The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.','2013-10-27','NSRP'),(30501,70460,'thyroid-stimulating hormone secretion','P','The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.','2013-10-27','NSRP'),(30502,70461,'SAGA-type complex','C','A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.','2013-10-27','NSRP'),(30503,70462,'plus-end specific microtubule depolymerization','P','The removal of tubulin heterodimers from the plus end of a microtubule.','2013-10-27','NSRP'),(30504,70463,'tubulin-dependent ATPase activity','F','Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.','2013-10-27','NSRP'),(30505,70464,'alphav-beta3 integrin-collagen alpha3(VI) complex','C','A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.','2013-10-27','NSRP'),(30506,70465,'alpha1-beta1 integrin-alpha3(VI) complex','C','A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.','2013-10-27','NSRP'),(30507,70466,'alpha2-beta1 integrin-alpha3(VI) complex','C','A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.','2013-10-27','NSRP'),(30508,70467,'RC-1 DNA recombination complex','C','A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5\'-3\' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.','2013-10-27','NSRP'),(30509,70468,'dentin secretion','P','The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.','2013-10-27','NSRP'),(30510,70469,'respiratory chain','C','The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.','2013-10-27','NSRP'),(30511,70470,'plasma membrane respiratory chain','C','A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.','2013-10-27','NSRP'),(30512,70471,'uterine smooth muscle contraction','P','A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.','2013-10-27','NSRP'),(30513,70472,'regulation of uterine smooth muscle contraction','P','Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.','2013-10-27','NSRP'),(30514,70473,'negative regulation of uterine smooth muscle contraction','P','Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.','2013-10-27','NSRP'),(30515,70474,'positive regulation of uterine smooth muscle contraction','P','Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.','2013-10-27','NSRP'),(30516,70475,'rRNA base methylation','P','The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.','2013-10-27','NSRP'),(30517,70476,'rRNA (guanine-N7)-methylation','P','The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.','2013-10-27','NSRP'),(30518,70477,'endospore core','C','An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.','2013-10-27','NSRP'),(30519,70478,'nuclear-transcribed mRNA catabolic process, 3\'-5\' exonucleolytic nonsense-mediated decay','P','The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3\' end is not protected by a 3\'-poly(A) tail; degradation proceeds in the 3\' to 5\' direction.','2013-10-27','NSRP'),(30520,70479,'nuclear-transcribed mRNA catabolic process, 5\'-3\' exonucleolytic nonsense-mediated decay','P','The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5\' end is not protected by a 5\'-cap; degradation proceeds in the 5\' to 3\' direction.','2013-10-27','NSRP'),(30521,70480,'exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay','P','The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5\'-cap.','2013-10-27','NSRP'),(30522,70481,'nuclear-transcribed mRNA catabolic process, non-stop decay','P','The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.','2013-10-27','NSRP'),(30523,70482,'response to oxygen levels','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.','2013-10-27','NSRP'),(30524,70483,'detection of hypoxia','P','The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.','2013-10-27','NSRP'),(30525,70484,'dehydro-D-arabinono-1,4-lactone metabolic process','P','The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.','2013-10-27','NSRP'),(30526,70485,'dehydro-D-arabinono-1,4-lactone biosynthetic process','P','The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.','2013-10-27','NSRP'),(30527,70486,'leukocyte aggregation','P','The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.','2013-10-27','NSRP'),(30528,70487,'monocyte aggregation','P','The adhesion of one monocyte to one or more other monocytes via adhesion molecules.','2013-10-27','NSRP'),(30529,70488,'neutrophil aggregation','P','The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.','2013-10-27','NSRP'),(30530,70489,'T cell aggregation','P','The adhesion of one T cell to one or more other T cells via adhesion molecules.','2013-10-27','NSRP'),(30531,70490,'protein pupylation','P','The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.','2013-10-27','NSRP'),(30532,70491,'repressing transcription factor binding','F','Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.','2013-10-27','NSRP'),(30533,70492,'oligosaccharide binding','F','Interacting selectively and non-covalently with any oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.','2013-10-27','NSRP'),(30534,70493,'thrombin receptor signaling pathway','P','The series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(30535,70494,'regulation of thrombin receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of a thrombin receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(30536,70495,'negative regulation of thrombin receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(30537,70496,'positive regulation of thrombin receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of thrombin receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(30538,70497,'6-carboxy-5,6,7,8-tetrahydropterin synthase activity','F','Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.','2013-10-27','NSRP'),(30539,70498,'interleukin-1-mediated signaling pathway','P','A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30540,70499,'exosporium assembly','P','A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.','2013-10-27','NSRP'),(30541,70500,'poly-gamma-glutamate metabolic process','P','The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.','2013-10-27','NSRP'),(30542,70501,'poly-gamma-glutamate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.','2013-10-27','NSRP'),(30543,70502,'capsule poly-gamma-glutamate biosynthetic process','P','The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.','2013-10-27','NSRP'),(30544,70503,'selenium-containing prosthetic group metabolic process','P','The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.','2013-10-27','NSRP'),(30545,70504,'selenium-containing prosthetic group biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.','2013-10-27','NSRP'),(30546,70505,'pollen coat','C','A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.','2013-10-27','NSRP'),(30547,70506,'high-density lipoprotein particle receptor activity','F','Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.','2013-10-27','NSRP'),(30548,70507,'regulation of microtubule cytoskeleton organization','P','Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.','2013-10-27','NSRP'),(30549,70508,'cholesterol import','P','The directed movement of cholesterol into a cell or organelle.','2013-10-27','NSRP'),(30550,70509,'calcium ion import','P','The directed movement of calcium ions into a cell or organelle.','2013-10-27','NSRP'),(30551,70510,'regulation of histone H4-K20 methylation','P','Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.','2013-10-27','NSRP'),(30552,70511,'negative regulation of histone H4-K20 methylation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.','2013-10-27','NSRP'),(30553,70512,'positive regulation of histone H4-K20 methylation','P','Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.','2013-10-27','NSRP'),(30554,70513,'death domain binding','F','Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.','2013-10-27','NSRP'),(30555,70514,'SRF-myogenin-E12 complex','C','A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.','2013-10-27','NSRP'),(30556,70515,'alphaIIb-beta3 integrin-talin complex','C','A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.','2013-10-27','NSRP'),(30557,70516,'CAK-ERCC2 complex','C','A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.','2013-10-27','NSRP'),(30558,70517,'DNA replication factor C core complex','C','A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.','2013-10-27','NSRP'),(30559,70518,'alpha4-beta1 integrin-CD53 complex','C','A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.','2013-10-27','NSRP'),(30560,70519,'alpha4-beta1 integrin-CD63 complex','C','A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.','2013-10-27','NSRP'),(30561,70520,'alpha4-beta1 integrin-CD81 complex','C','A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.','2013-10-27','NSRP'),(30562,70521,'alpha4-beta1 integrin-CD82 complex','C','A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.','2013-10-27','NSRP'),(30563,70522,'ERCC4-ERCC1 complex','C','A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.','2013-10-27','NSRP'),(30564,70523,'11-beta-hydroxysteroid dehydrogenase (NAD+) activity','F','Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.','2013-10-27','NSRP'),(30565,70524,'11-beta-hydroxysteroid dehydrogenase (NADP+) activity','F','Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.','2013-10-27','NSRP'),(30566,70525,'threonylcarbamoyladenosine metabolic process','P','The chemical reactions and pathways involving threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.','2013-10-27','NSRP'),(30567,70526,'threonylcarbamoyladenosine biosynthetic process','P','The chemical reactions and pathways resulting in the formation of threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.','2013-10-27','NSRP'),(30568,70527,'platelet aggregation','P','The adhesion of one platelet to one or more other platelets via adhesion molecules.','2013-10-27','NSRP'),(30569,70528,'protein kinase C signaling cascade','P','A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.','2013-10-27','NSRP'),(30570,70529,'L-tryptophan aminotransferase activity','F','Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.','2013-10-27','NSRP'),(30571,70530,'K63-linked polyubiquitin binding','F','Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers.','2013-10-27','NSRP'),(30572,70531,'BRCA1-A complex','C','A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.','2013-10-27','NSRP'),(30573,70532,'BRCA1-B complex','C','A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.','2013-10-27','NSRP'),(30574,70533,'BRCA1-C complex','C','A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.','2013-10-27','NSRP'),(30575,70534,'protein K63-linked ubiquitination','P','A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.','2013-10-27','NSRP'),(30576,70535,'histone H2A K63-linked ubiquitination','P','A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.','2013-10-27','NSRP'),(30577,70536,'protein K63-linked deubiquitination','P','A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.','2013-10-27','NSRP'),(30578,70537,'histone H2A K63-linked deubiquitination','P','A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.','2013-10-27','NSRP'),(30579,70538,'oleic acid binding','F','Interacting selectively and non-covalently with oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.','2013-10-27','NSRP'),(30580,70539,'linoleic acid binding','F','Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.','2013-10-27','NSRP'),(30581,70540,'stearic acid binding','F','Interacting selectively and non-covalently with stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.','2013-10-27','NSRP'),(30582,70541,'response to platinum ion','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.','2013-10-27','NSRP'),(30583,70542,'response to fatty acid','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.','2013-10-27','NSRP'),(30584,70543,'response to linoleic acid','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.','2013-10-27','NSRP'),(30585,70544,'histone H3-K36 demethylation','P','The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.','2013-10-27','NSRP'),(30586,70545,'PeBoW complex','C','A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.','2013-10-27','NSRP'),(30587,70546,'L-phenylalanine aminotransferase activity','F','Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.','2013-10-27','NSRP'),(30588,70547,'L-tyrosine aminotransferase activity','F','Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.','2013-10-27','NSRP'),(30589,70548,'L-glutamine aminotransferase activity','F','Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.','2013-10-27','NSRP'),(30590,70549,'negative regulation of translation involved in RNA interference','P','A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA.','2013-10-27','NSRP'),(30591,70550,'rDNA condensation','P','The cell cycle process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.','2013-10-27','NSRP'),(30592,70551,'endoribonuclease activity, cleaving siRNA-paired mRNA','F','Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5\'-phosphomonoesters.','2013-10-27','NSRP'),(30593,70552,'BRISC complex','C','A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.','2013-10-27','NSRP'),(30594,70553,'nicotinic acid receptor activity','F','Combining with nicotinic acid to initiate a change in cell activity.','2013-10-27','NSRP'),(30595,70554,'synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex','C','A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).','2013-10-27','NSRP'),(30596,70555,'response to interleukin-1','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.','2013-10-27','NSRP'),(30597,70556,'TAF4B-containing transcription factor TFIID complex','C','A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.','2013-10-27','NSRP'),(30598,70557,'PCNA-p21 complex','C','A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.','2013-10-27','NSRP'),(30599,70558,'alphaM-beta2 integrin-CD63 complex','C','A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.','2013-10-27','NSRP'),(30600,70559,'lysosomal multienzyme complex','C','A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.','2013-10-27','NSRP'),(30601,70560,'protein secretion by platelet','P','The regulated release of proteins by a platelet or group of platelets.','2013-10-27','NSRP'),(30602,70561,'vitamin D receptor signaling pathway','P','The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.','2013-10-27','NSRP'),(30603,70562,'regulation of vitamin D receptor signaling pathway','P','Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.','2013-10-27','NSRP'),(30604,70563,'negative regulation of vitamin D receptor signaling pathway','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.','2013-10-27','NSRP'),(30605,70564,'positive regulation of vitamin D receptor signaling pathway','P','Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.','2013-10-27','NSRP'),(30606,70565,'telomere-telomerase complex','C','A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.','2013-10-27','NSRP'),(30607,70566,'adenylyltransferase activity','F','Catalysis of the transfer of an adenylyl group to an acceptor.','2013-10-27','NSRP'),(30608,70567,'cytidylyltransferase activity','F','Catalysis of the transfer of a cytidylyl group to an acceptor.','2013-10-27','NSRP'),(30609,70568,'guanylyltransferase activity','F','Catalysis of the transfer of a guanylyl group to an acceptor.','2013-10-27','NSRP'),(30610,70569,'uridylyltransferase activity','F','Catalysis of the transfer of an uridylyl group to an acceptor.','2013-10-27','NSRP'),(30611,70570,'regulation of neuron projection regeneration','P','Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.','2013-10-27','NSRP'),(30612,70571,'negative regulation of neuron projection regeneration','P','Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.','2013-10-27','NSRP'),(30613,70572,'positive regulation of neuron projection regeneration','P','Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.','2013-10-27','NSRP'),(30614,70573,'metallodipeptidase activity','F','Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.','2013-10-27','NSRP'),(30615,70574,'cadmium ion transmembrane transport','P','A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30616,70575,'peptide mating pheromone maturation involved in pheromone-induced unidirectional conjugation','P','The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.','2013-10-27','NSRP'),(30617,70576,'vitamin D 24-hydroxylase activity','F','Catalysis of the hydroxylation of C-24 of any form of vitamin D.','2013-10-27','NSRP'),(30618,70577,'histone acetyl-lysine binding','F','Interacting selectively and non-covalently with an acetylated lysine residue within a histone.','2013-10-27','NSRP'),(30619,70578,'RISC-loading complex','C','A trimeric ribonucleoprotein complex that and is required for the formation of a mature RNA induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1) and TRBP (TARBP2) in association with the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP.','2013-10-27','NSRP'),(30620,70579,'methylcytosine dioxygenase activity','F','Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.','2013-10-27','NSRP'),(30621,70580,'base J metabolic process','P','The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.','2013-10-27','NSRP'),(30622,70581,'rolling circle DNA replication','P','A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.','2013-10-27','NSRP'),(30623,70582,'theta DNA replication','P','A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.','2013-10-27','NSRP'),(30624,70583,'spore membrane bending pathway','P','The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.','2013-10-27','NSRP'),(30625,70584,'mitochondrion morphogenesis','P','The process in which the anatomical structures of a mitochondrion are generated and organized.','2013-10-27','NSRP'),(30626,70585,'protein localization to mitochondrion','P','A process in which a protein is transported to, or maintained in, a location within the mitochondrion.','2013-10-27','NSRP'),(30627,70586,'cell-cell adhesion involved in gastrulation','P','The attachment of one cell to another cell affecting gastrulation.','2013-10-27','NSRP'),(30628,70587,'regulation of cell-cell adhesion involved in gastrulation','P','Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.','2013-10-27','NSRP'),(30629,70588,'calcium ion transmembrane transport','P','A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30630,70589,'cellular component macromolecule biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.','2013-10-27','NSRP'),(30631,70590,'spore wall biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.','2013-10-27','NSRP'),(30632,70591,'ascospore wall biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.','2013-10-27','NSRP'),(30633,70592,'cell wall polysaccharide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.','2013-10-27','NSRP'),(30634,70593,'dendrite self-avoidance','P','The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.','2013-10-27','NSRP'),(30635,70594,'juvenile hormone response element binding','F','Interacting selectively and non-covalently with the juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.','2013-10-27','NSRP'),(30636,70595,'(1->3)-alpha-glucan metabolic process','P','The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30637,70596,'(1->3)-alpha-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30638,70597,'cell wall (1->3)-alpha-glucan metabolic process','P','The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.','2013-10-27','NSRP'),(30639,70598,'cell wall (1->3)-alpha-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.','2013-10-27','NSRP'),(30640,70599,'fungal-type cell wall (1->3)-alpha-glucan metabolic process','P','The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.','2013-10-27','NSRP'),(30641,70600,'fungal-type cell wall (1->3)-alpha-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.','2013-10-27','NSRP'),(30642,70601,'centromeric sister chromatid cohesion','P','The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.','2013-10-27','NSRP'),(30643,70602,'regulation of centromeric sister chromatid cohesion','P','Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.','2013-10-27','NSRP'),(30644,70603,'SWI/SNF superfamily-type complex','C','A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the core components and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.','2013-10-27','NSRP'),(30645,70604,'PBAF complex','C','A SWI/SNF-type complex that contains the ATPase product of the mammalian BAF180 gene.','2013-10-27','NSRP'),(30646,70605,'regulation of (1->3)-alpha-glucan metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30647,70606,'regulation of (1->3)-alpha-glucan biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30648,70607,'regulation of cell wall (1->3)-alpha-glucan metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.','2013-10-27','NSRP'),(30649,70608,'regulation of cell wall (1->3)-alpha-glucan biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.','2013-10-27','NSRP'),(30650,70609,'regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.','2013-10-27','NSRP'),(30651,70610,'regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.','2013-10-27','NSRP'),(30652,70611,'histone methyltransferase activity (H3-R2 specific)','F','Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3.','2013-10-27','NSRP'),(30653,70612,'histone methyltransferase activity (H2A-R3 specific)','F','Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A.','2013-10-27','NSRP'),(30654,70613,'regulation of protein processing','P','Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.','2013-10-27','NSRP'),(30655,70614,'tungstate ion transport','P','The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.','2013-10-27','NSRP'),(30656,70615,'nucleosome-dependent ATPase activity','F','Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes.','2013-10-27','NSRP'),(30657,70616,'regulation of thiamine diphosphate biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.','2013-10-27','NSRP'),(30658,70617,'negative regulation of thiamine diphosphate biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.','2013-10-27','NSRP'),(30659,70618,'Grb2-Sos complex','C','A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30660,70619,'Shc-Grb2-Sos complex','C','A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30661,70620,'EGFR-Grb2-Sos complex','C','A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30662,70621,'EGFR-Shc-Grb2-Sos complex','C','A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.','2013-10-27','NSRP'),(30663,70622,'UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex','C','A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.','2013-10-27','NSRP'),(30664,70623,'regulation of thiamine biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.','2013-10-27','NSRP'),(30665,70624,'negative regulation of thiamine biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.','2013-10-27','NSRP'),(30666,70625,'zymogen granule exocytosis','P','The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.','2013-10-27','NSRP'),(30667,70626,'(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity','F','Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.','2013-10-27','NSRP'),(30668,70627,'ferrous iron import','P','The directed movement of ferrous iron (Fe(II) or Fe2+) ions across a membrane into a cell or organelle.','2013-10-27','NSRP'),(30669,70628,'proteasome binding','F','Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.','2013-10-27','NSRP'),(30670,70629,'(1->4)-alpha-glucan metabolic process','P','The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30671,70630,'(1->4)-alpha-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.','2013-10-27','NSRP'),(30672,70631,'spindle pole body localization','P','Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.','2013-10-27','NSRP'),(30673,70632,'establishment of spindle pole body localization','P','Any process in which a spindle pole body is transported to a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.','2013-10-27','NSRP'),(30674,70633,'transepithelial transport','P','The directed movement of a substance from one side of an epithelium to the other.','2013-10-27','NSRP'),(30675,70634,'transepithelial ammonium transport','P','The directed movement of ammonium ions from one side of an epithelium to the other.','2013-10-27','NSRP'),(30676,70635,'nicotinamide riboside hydrolase activity','F','Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.','2013-10-27','NSRP'),(30677,70636,'nicotinic acid riboside hydrolase activity','F','Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.','2013-10-27','NSRP'),(30678,70637,'pyridine nucleoside metabolic process','P','The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.','2013-10-27','NSRP'),(30679,70638,'pyridine nucleoside catabolic process','P','The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.','2013-10-27','NSRP'),(30680,70639,'vitamin D2 metabolic process','P','The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.','2013-10-27','NSRP'),(30681,70640,'vitamin D3 metabolic process','P','The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.','2013-10-27','NSRP'),(30682,70641,'vitamin D4 metabolic process','P','The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.','2013-10-27','NSRP'),(30683,70642,'vitamin D5 metabolic process','P','The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.','2013-10-27','NSRP'),(30684,70643,'vitamin D 25-hydroxylase activity','F','Catalysis of the hydroxylation of C-25 of any form of vitamin D.','2013-10-27','NSRP'),(30685,70644,'vitamin D response element binding','F','Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.','2013-10-27','NSRP'),(30686,70645,'Ubisch body','C','A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.','2013-10-27','NSRP'),(30687,70646,'protein modification by small protein removal','P','A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.','2013-10-27','NSRP'),(30688,70647,'protein modification by small protein conjugation or removal','P','A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.','2013-10-27','NSRP'),(30689,70648,'formin-nucleated actin cable','C','An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.','2013-10-27','NSRP'),(30690,70649,'formin-nucleated actin cable assembly','P','The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.','2013-10-27','NSRP'),(30691,70650,'actin filament bundle distribution','P','Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.','2013-10-27','NSRP'),(30692,70651,'nonfunctional rRNA decay','P','An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.','2013-10-27','NSRP'),(30693,70652,'HAUS complex','C','A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.','2013-10-27','NSRP'),(30694,70653,'high-density lipoprotein particle receptor binding','F','Interacting selectively and non-covalently with a high-density lipoprotein receptor.','2013-10-27','NSRP'),(30695,70654,'sensory epithelium regeneration','P','The regrowth of a sensory epithelium following its loss or destruction.','2013-10-27','NSRP'),(30696,70655,'mechanosensory epithelium regeneration','P','The regrowth of lost or destroyed mechanosensory epithelia.','2013-10-27','NSRP'),(30697,70656,'mechanoreceptor differentiation involved in mechanosensory epithelium regeneration','P','Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.','2013-10-27','NSRP'),(30698,70657,'neuromast regeneration','P','The regrowth of a neuromast following its loss or destruction.','2013-10-27','NSRP'),(30699,70658,'neuromast hair cell differentiation involved in neuromast regeneration','P','Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.','2013-10-27','NSRP'),(30700,70659,'inner ear sensory epithelium regeneration','P','The regrowth of lost or destroyed inner ear sensory epithelia.','2013-10-27','NSRP'),(30701,70660,'inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration','P','Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.','2013-10-27','NSRP'),(30702,70661,'leukocyte proliferation','P','The expansion of a leukocyte population by cell division.','2013-10-27','NSRP'),(30703,70662,'mast cell proliferation','P','The expansion of a mast cell population by cell division.','2013-10-27','NSRP'),(30704,70663,'regulation of leukocyte proliferation','P','Any process that modulates the frequency, rate or extent of leukocyte proliferation.','2013-10-27','NSRP'),(30705,70664,'negative regulation of leukocyte proliferation','P','Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.','2013-10-27','NSRP'),(30706,70665,'positive regulation of leukocyte proliferation','P','Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.','2013-10-27','NSRP'),(30707,70666,'regulation of mast cell proliferation','P','Any process that modulates the frequency, rate or extent of mast cell proliferation.','2013-10-27','NSRP'),(30708,70667,'negative regulation of mast cell proliferation','P','Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.','2013-10-27','NSRP'),(30709,70668,'positive regulation of mast cell proliferation','P','Any process that activates or increases the rate or extent of mast cell proliferation.','2013-10-27','NSRP'),(30710,70669,'response to interleukin-2','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.','2013-10-27','NSRP'),(30711,70670,'response to interleukin-4','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.','2013-10-27','NSRP'),(30712,70671,'response to interleukin-12','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.','2013-10-27','NSRP'),(30713,70672,'response to interleukin-15','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.','2013-10-27','NSRP'),(30714,70673,'response to interleukin-18','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.','2013-10-27','NSRP'),(30715,70674,'hypoxanthine dehydrogenase activity','F','Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.','2013-10-27','NSRP'),(30716,70675,'hypoxanthine oxidase activity','F','Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.','2013-10-27','NSRP'),(30717,70676,'intralumenal vesicle formation','P','The evagination of the endosome membrane, resulting in the formation of a vesicle.','2013-10-27','NSRP'),(30718,70677,'rRNA (cytosine-2\'-O-)-methyltransferase activity','F','Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2\'-O-methylcytosine.','2013-10-27','NSRP'),(30719,70678,'preprotein binding','F','Interacting selectively and non-covalently with a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.','2013-10-27','NSRP'),(30720,70679,'inositol 1,4,5 trisphosphate binding','F','Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate.','2013-10-27','NSRP'),(30721,70680,'asparaginyl-tRNAAsn biosynthesis via transamidation','P','A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.','2013-10-27','NSRP'),(30722,70681,'glutaminyl-tRNAGln biosynthesis via transamidation','P','A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.','2013-10-27','NSRP'),(30723,70682,'proteasome regulatory particle assembly','P','The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.','2013-10-27','NSRP'),(30724,70683,'mitotic cell cycle G2/M transition decatenation checkpoint','P','A mitotic cell cycle checkpoint that blocks cell cycle progression from G2 to M phase until sister chromatids are sufficiently separated, with concatenated molecules topologically resolved.','2012-03-14','NSRP'),(30725,70684,'seminal clot liquefaction','P','The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.','2013-10-27','NSRP'),(30726,70685,'macropinocytic cup','C','A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.','2013-10-27','NSRP'),(30727,70686,'macropinocytic cup membrane','C','The portion of the plasma membrane surrounding a macropinocytic cup.','2013-10-27','NSRP'),(30728,70687,'macropinocytic cup cytoskeleton','C','The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.','2013-10-27','NSRP'),(30729,70688,'MLL5-L complex','C','A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively.','2013-10-27','NSRP'),(30730,70689,'L-threonine catabolic process to propionate','P','The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.','2013-10-27','NSRP'),(30731,70690,'L-threonine catabolic process to acetyl-CoA','P','The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.','2013-10-27','NSRP'),(30732,70691,'dimeric positive transcription elongation factor complex b','C','A positive transcription elongation factor complex b that comprises two subunits; an example is the budding yeast complex containing Svg1p (also called Bur1p) and Bur2p.','2013-10-27','NSRP'),(30733,70692,'trimeric positive transcription elongation factor complex b','C','A positive transcription elongation factor complex b that comprises three subunits; an example is the budding yeast Ctk complex, which consists of Ctk1p, Ctk2p and Ctk3p.','2013-10-27','NSRP'),(30734,70693,'P-TEFb-cap methyltransferase complex','C','A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.','2013-10-27','NSRP'),(30735,70694,'deoxyribonucleoside 5\'-monophosphate N-glycosidase activity','F','Catalysis of the reaction: a deoxyribonucleoside 5\'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.','2013-10-27','NSRP'),(30736,70695,'FHF complex','C','A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).','2013-10-27','NSRP'),(30737,70696,'transmembrane receptor protein serine/threonine kinase binding','F','Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.','2013-10-27','NSRP'),(30738,70697,'activin receptor binding','F','Interacting selectively and non-covalently with an activin receptor.','2013-10-27','NSRP'),(30739,70698,'type I activin receptor binding','F','Interacting selectively and non-covalently with a type I activin receptor.','2013-10-27','NSRP'),(30740,70699,'type II activin receptor binding','F','Interacting selectively and non-covalently with a type II activin receptor.','2013-10-27','NSRP'),(30741,70700,'BMP receptor binding','F','Interacting selectively and non-covalently with a BMP receptor.','2013-10-27','NSRP'),(30742,70701,'mucus layer','C','An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.','2013-10-27','NSRP'),(30743,70702,'inner mucus layer','C','The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.','2013-10-27','NSRP'),(30744,70703,'outer mucus layer','C','The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.','2013-10-27','NSRP'),(30745,70704,'sterol desaturase activity','F','Catalysis of the introduction of a double bond into a sterol molecule.','2013-10-27','NSRP'),(30746,70705,'RNA nucleotide insertion','P','The modification of an RNA molecule by insertion of one or more nucleotides.','2013-10-27','NSRP'),(30747,70706,'RNA nucleotide deletion','P','The modification of an RNA molecule by removal of a single nucleotide.','2013-10-27','NSRP'),(30748,70707,'RNA dinucleotide insertion','P','The modification of an RNA molecule by insertion of a dinucleotide.','2013-10-27','NSRP'),(30749,70708,'RNA cytidine insertion','P','The modification of an RNA molecule by insertion of a cytidine nucleotide.','2013-10-27','NSRP'),(30750,70709,'RNA guanosine insertion','P','The modification of an RNA molecule by insertion of a guanosine nucleotide.','2013-10-27','NSRP'),(30751,70710,'RNA uridine deletion','P','The modification of an RNA molecule by removal of a uridine nucleotide.','2013-10-27','NSRP'),(30752,70711,'RNA adenosine-uridine insertion','P','The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.','2013-10-27','NSRP'),(30753,70712,'RNA cytidine-uridine insertion','P','The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.','2013-10-27','NSRP'),(30754,70713,'RNA guanosine-cytidine insertion','P','The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.','2013-10-27','NSRP'),(30755,70714,'RNA guanosine-uridine insertion','P','The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.','2013-10-27','NSRP'),(30756,70715,'sodium-dependent organic cation transport','P','The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30757,70716,'mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication','P','A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.','2013-10-27','NSRP'),(30758,70717,'poly-purine tract binding','F','Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule.','2013-10-27','NSRP'),(30759,70718,'alphaPDGFR-SHP-2 complex','C','A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.','2013-10-27','NSRP'),(30760,70719,'alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex','C','A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.','2013-10-27','NSRP'),(30761,70720,'Grb2-SHP-2 complex','C','A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.','2013-10-27','NSRP'),(30762,70721,'ISGF3 complex','C','A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.','2013-10-27','NSRP'),(30763,70722,'Tle3-Aes complex','C','A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.','2013-10-27','NSRP'),(30764,70723,'response to cholesterol','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.','2013-10-27','NSRP'),(30765,70724,'BMP receptor complex','C','A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.','2013-10-27','NSRP'),(30766,70725,'Yb body','C','A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.','2013-10-27','NSRP'),(30767,70726,'cell wall assembly','P','The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.','2013-10-27','NSRP'),(30768,70727,'cellular macromolecule localization','P','Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.','2013-10-27','NSRP'),(30769,70728,'leucine binding','F','Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid.','2013-10-27','NSRP'),(30770,70729,'cyclic nucleotide transport','P','The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.','2013-10-27','NSRP'),(30771,70730,'cAMP transport','P','The directed movement of cyclic AMP (cAMP), into, out of or within a cell.','2013-10-27','NSRP'),(30772,70731,'cGMP transport','P','The directed movement of cyclic GMP (cGMP), into, out of or within a cell.','2013-10-27','NSRP'),(30773,70732,'spindle envelope','C','An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.','2013-10-27','NSRP'),(30774,70733,'protein adenylyltransferase activity','F','Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5\'-monophosphate; AMP group) to specific residues of target proteins.','2013-10-27','NSRP'),(30775,70734,'histone H3-K27 methylation','P','The modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.','2013-10-27','NSRP'),(30776,70735,'protein-glycine ligase activity','F','Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein.','2013-10-27','NSRP'),(30777,70736,'protein-glycine ligase activity, initiating','F','Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.','2013-10-27','NSRP'),(30778,70737,'protein-glycine ligase activity, elongating','F','Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.','2013-10-27','NSRP'),(30779,70738,'tubulin-glycine ligase activity','F','Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.','2013-10-27','NSRP'),(30780,70739,'protein-glutamic acid ligase activity','F','Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.','2013-10-27','NSRP'),(30781,70740,'tubulin-glutamic acid ligase activity','F','Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.','2013-10-27','NSRP'),(30782,70741,'response to interleukin-6','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.','2013-10-27','NSRP'),(30783,70742,'C2H2 zinc finger domain binding','F','Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.','2013-10-27','NSRP'),(30784,70743,'interleukin-23 complex','C','A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.','2013-10-27','NSRP'),(30785,70744,'interleukin-27 complex','C','A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.','2013-10-27','NSRP'),(30786,70745,'interleukin-35 complex','C','A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.','2013-10-27','NSRP'),(30787,70746,'interleukin-35 binding','F','Interacting selectively and non-covalently with interleukin-35.','2013-10-27','NSRP'),(30788,70747,'interleukin-35 receptor activity','F','Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.','2013-10-27','NSRP'),(30789,70748,'interleukin-35 receptor binding','F','Interacting selectively and non-covalently with the interleukin-35 receptor.','2013-10-27','NSRP'),(30790,70749,'interleukin-35 biosynthetic process','P','The chemical reactions and pathways resulting in the formation of interleukin-35.','2013-10-27','NSRP'),(30791,70750,'regulation of interleukin-35 biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.','2013-10-27','NSRP'),(30792,70751,'negative regulation of interleukin-35 biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.','2013-10-27','NSRP'),(30793,70752,'positive regulation of interleukin-35 biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.','2013-10-27','NSRP'),(30794,70753,'interleukin-35 production','P','The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.','2013-10-27','NSRP'),(30795,70754,'regulation of interleukin-35 production','P','Any process that modulates the frequency, rate, or extent of interleukin-35 production.','2013-10-27','NSRP'),(30796,70755,'negative regulation of interleukin-35 production','P','Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.','2013-10-27','NSRP'),(30797,70756,'positive regulation of interleukin-35 production','P','Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.','2013-10-27','NSRP'),(30798,70757,'interleukin-35-mediated signaling pathway','P','A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.','2013-10-27','NSRP'),(30799,70758,'regulation of interleukin-35-mediated signaling pathway','P','Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.','2013-10-27','NSRP'),(30800,70759,'negative regulation of interleukin-35-mediated signaling pathway','P','Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.','2013-10-27','NSRP'),(30801,70760,'positive regulation of interleukin-35-mediated signaling pathway','P','Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.','2013-10-27','NSRP'),(30802,70761,'pre-snoRNP complex','C','A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.','2013-10-27','NSRP'),(30803,70762,'nuclear pore transmembrane ring','C','A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical \'spokes\' around the central transport channel. A single \'spoke\', can be isolated and is sometime referred to as the Ndc1 complex.','2013-10-27','NSRP'),(30804,70763,'Delta1 complex','C','A protein complex that consists of homodimer of the Notch ligand Delta1.','2013-10-27','NSRP'),(30805,70764,'gamma-secretase-Delta1 complex','C','A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.','2013-10-27','NSRP'),(30806,70765,'gamma-secretase complex','C','A protein complex that has aspartic-type endopeptidase activity, and contains a catalytic subunit, presenilin (PS), that is a prototypical member of the GxGD-type aspartyl peptidases. The complex also contains additional subunits, including nicastrin, APH-1, PEN-2, and a regulatory subunit, CD147. Gamma-secretase cleaves several transmembrane proteins including the cell surface receptor Notch and the beta-amyloid precursor protein.','2013-10-27','NSRP'),(30807,70766,'endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex','C','A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).','2013-10-27','NSRP'),(30808,70767,'BRCA1-Rad51 complex','C','A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.','2013-10-27','NSRP'),(30809,70768,'synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex','C','A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).','2013-10-27','NSRP'),(30810,70769,'alphaIIb-beta3 integrin-CIB complex','C','A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.','2013-10-27','NSRP'),(30811,70770,'alphaIIb-beta3 integrin-CD47-FAK complex','C','A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.','2013-10-27','NSRP'),(30812,70771,'alphaIIb-beta3 integrin-CD47-Src complex','C','A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.','2013-10-27','NSRP'),(30813,70772,'PAS complex','C','A protein complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.','2013-10-27','NSRP'),(30814,70773,'protein-N-terminal glutamine amidohydrolase activity','F','Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.','2013-10-27','NSRP'),(30815,70774,'phytoceramidase activity','F','Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.','2013-10-27','NSRP'),(30816,70775,'H3 histone acetyltransferase complex','C','A multisubunit complex that catalyzes the acetylation of histone H3.','2013-10-27','NSRP'),(30817,70776,'MOZ/MORF histone acetyltransferase complex','C','A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.','2013-10-27','NSRP'),(30818,70777,'D-aspartate transport','P','The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30819,70778,'L-aspartate transport','P','The directed movement of L-aspartate, the L-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30820,70779,'D-aspartate import','P','The directed movement of D-aspartate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.','2013-10-27','NSRP'),(30821,70780,'dihydrosphingosine-1-phosphate phosphatase activity','F','Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.','2013-10-27','NSRP'),(30822,70781,'response to biotin','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.','2013-10-27','NSRP'),(30823,70782,'phosphatidylserine exposure on apoptotic cell surface','P','A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an \'eat-me\' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.','2013-10-27','NSRP'),(30824,70783,'growth of unicellular organism as a thread of attached cells','P','A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.','2013-10-27','NSRP'),(30825,70784,'regulation of growth of unicellular organism as a thread of attached cells','P','Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.','2013-10-27','NSRP'),(30826,70785,'negative regulation of growth of unicellular organism as a thread of attached cells','P','Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.','2013-10-27','NSRP'),(30827,70786,'positive regulation of growth of unicellular organism as a thread of attached cells','P','Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.','2013-10-27','NSRP'),(30828,70787,'conidiophore development','P','The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.','2013-10-27','NSRP'),(30829,70788,'conidiophore stalk development','P','The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.','2013-10-27','NSRP'),(30830,70789,'metula development','P','The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.','2013-10-27','NSRP'),(30831,70790,'phialide development','P','The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.','2013-10-27','NSRP'),(30832,70791,'cleistothecium development','P','The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.','2013-10-27','NSRP'),(30833,70792,'Hulle cell development','P','The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.','2013-10-27','NSRP'),(30834,70793,'regulation of conidiophore development','P','Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.','2013-10-27','NSRP'),(30835,70794,'negative regulation of conidiophore development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.','2013-10-27','NSRP'),(30836,70795,'positive regulation of conidiophore development','P','Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.','2013-10-27','NSRP'),(30837,70796,'regulation of cleistothecium development','P','Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.','2013-10-27','NSRP'),(30838,70797,'negative regulation of cleistothecium development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.','2013-10-27','NSRP'),(30839,70798,'positive regulation of cleistothecium development','P','Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.','2013-10-27','NSRP'),(30840,70799,'regulation of conidiophore stalk development','P','Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.','2013-10-27','NSRP'),(30841,70800,'negative regulation of conidiophore stalk development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.','2013-10-27','NSRP'),(30842,70801,'positive regulation of conidiophore stalk development','P','Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.','2013-10-27','NSRP'),(30843,70802,'regulation of metula development','P','Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.','2013-10-27','NSRP'),(30844,70803,'negative regulation of metula development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.','2013-10-27','NSRP'),(30845,70804,'positive regulation of metula development','P','Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.','2013-10-27','NSRP'),(30846,70805,'regulation of phialide development','P','Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.','2013-10-27','NSRP'),(30847,70806,'negative regulation of phialide development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.','2013-10-27','NSRP'),(30848,70807,'positive regulation of phialide development','P','Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.','2013-10-27','NSRP'),(30849,70808,'regulation of Hulle cell development','P','Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.','2013-10-27','NSRP'),(30850,70809,'negative regulation of Hulle cell development','P','Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.','2013-10-27','NSRP'),(30851,70810,'positive regulation of Hulle cell development','P','Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.','2013-10-27','NSRP'),(30852,70811,'glycerol-2-phosphate transport','P','The directed movement of glycerol-2-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol-2-phosphate is a phosphoric monoester of glycerol.','2013-10-27','NSRP'),(30853,70812,'glycerol-2-phosphate-transporting ATPase activity','F','Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-2-phosphate(out) = ADP + phosphate + glycerol-2-phosphate(in).','2013-10-27','NSRP'),(30854,70813,'hydrogen sulfide metabolic process','P','The chemical reactions and pathways involving hydrogen sulfide, H2S.','2013-10-27','NSRP'),(30855,70814,'hydrogen sulfide biosynthetic process','P','The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.','2013-10-27','NSRP'),(30856,70815,'peptidyl-lysine 5-dioxygenase activity','F','Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.','2013-10-27','NSRP'),(30857,70816,'phosphorylation of RNA polymerase II C-terminal domain','P','The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3\'-RNA processing machinery to the elongating RNA polymerase complex.','2013-10-27','NSRP'),(30858,70817,'P-TEFb-cap methyltransferase complex localization','P','Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.','2013-10-27','NSRP'),(30859,70818,'protoporphyrinogen oxidase activity','F','Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.','2013-10-27','NSRP'),(30860,70819,'menaquinone-dependent protoporphyrinogen oxidase activity','F','Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.','2013-10-27','NSRP'),(30861,70820,'tertiary granule','C','A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.','2013-10-27','NSRP'),(30862,70821,'tertiary granule membrane','C','The lipid bilayer surrounding a tertiary granule.','2013-10-27','NSRP'),(30863,70822,'Sin3-type complex','C','Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.','2013-10-27','NSRP'),(30864,70823,'HDA1 complex','C','A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.','2013-10-27','NSRP'),(30865,70824,'SHREC complex','C','A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.','2013-10-27','NSRP'),(30866,70825,'micropyle','C','An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the chorion that allows sperm entry into the egg prior to fertilization.','2013-10-27','NSRP'),(30867,70826,'paraferritin complex','C','A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.','2013-10-27','NSRP'),(30868,70827,'chromatin maintenance','P','The chromatin organization process that preserves chromatin in a stable functional or structural state.','2013-10-27','NSRP'),(30869,70828,'heterochromatin organization','P','Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.','2013-10-27','NSRP'),(30870,70829,'heterochromatin maintenance','P','The chromatin organization process that preserves heterochromatin in a stable functional or structural state.','2013-10-27','NSRP'),(30871,70830,'tight junction assembly','P','The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.','2013-10-27','NSRP'),(30872,70831,'basement membrane assembly','P','The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.','2013-10-27','NSRP'),(30873,70832,'phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline','P','The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.','2013-10-27','NSRP'),(30874,70833,'phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine','P','The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.','2013-10-27','NSRP'),(30875,70834,'phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine','P','The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.','2013-10-27','NSRP'),(30876,70835,'chromium ion transmembrane transporter activity','F','Catalysis of the transfer of chromium (Cr) ions from one side of a membrane to the other.','2013-10-27','NSRP'),(30877,70836,'caveola assembly','P','The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.','2013-10-27','NSRP'),(30878,70837,'dehydroascorbic acid transport','P','The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.','2013-10-27','NSRP'),(30879,70838,'divalent metal ion transport','P','The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.','2013-10-27','NSRP'),(30880,70839,'divalent metal ion export','P','The directed movement of divalent metal cations, any metal ion with a +2 electric charge, out of a cell or organelle.','2013-10-27','NSRP'),(30881,70840,'dynein complex binding','F','Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.','2013-10-27','NSRP'),(30882,70841,'inclusion body assembly','P','The aggregation, arrangement and bonding together of a set of components to form an inclusion body.','2013-10-27','NSRP'),(30883,70842,'aggresome assembly','P','The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.','2013-10-27','NSRP'),(30884,70843,'misfolded protein transport','P','The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.','2013-10-27','NSRP'),(30885,70844,'polyubiquitinated protein transport','P','The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.','2013-10-27','NSRP'),(30886,70845,'polyubiquitinated misfolded protein transport','P','The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.','2013-10-27','NSRP'),(30887,70846,'Hsp90 deacetylation','P','The modification of an Hsp90 protein by removal of acetyl groups.','2013-10-27','NSRP'),(30888,70847,'core mediator complex','C','A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.','2013-10-27','NSRP'),(30889,70848,'response to growth factor stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.','2013-10-27','NSRP'),(30890,70849,'response to epidermal growth factor stimulus','P','Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.','2013-10-27','NSRP'),(30891,70850,'TACC/TOG complex','C','A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.','2013-10-27','NSRP'),(30892,70851,'growth factor receptor binding','F','Interacting selectively and non-covalently with a growth factor receptor.','2013-10-27','NSRP'),(30893,70852,'cell body fiber','C','A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.','2013-10-27','NSRP'),(30894,70853,'myosin VI binding','F','Interacting selectively and non-covalently with a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.','2013-10-27','NSRP'),(30895,70854,'myosin VI heavy chain binding','F','Interacting selectively and non-covalently with a heavy chain of a myosin VI complex.','2013-10-27','NSRP'),(30896,70855,'myosin VI head/neck binding','F','Interacting selectively and non-covalently with the head/neck region of a myosin VI heavy chain.','2013-10-27','NSRP'),(30897,70856,'myosin VI light chain binding','F','Interacting selectively and non-covalently with a light chain of a myosin VI complex.','2013-10-27','NSRP'),(30898,70857,'regulation of bile acid biosynthetic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.','2013-10-27','NSRP'),(30899,70858,'negative regulation of bile acid biosynthetic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.','2013-10-27','NSRP'),(30900,70859,'positive regulation of bile acid biosynthetic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.','2013-10-27','NSRP'),(30901,70860,'RNA polymerase I core factor complex','C','A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.','2013-10-27','NSRP'),(30902,70861,'regulation of protein exit from endoplasmic reticulum','P','Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.','2013-10-27','NSRP'),(30903,70862,'negative regulation of protein exit from endoplasmic reticulum','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.','2013-10-27','NSRP'),(30904,70863,'positive regulation of protein exit from endoplasmic reticulum','P','Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.','2013-10-27','NSRP'),(30905,70864,'sperm individualization complex','C','A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.','2013-10-27','NSRP'),(30906,70865,'investment cone','C','A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.','2013-10-27','NSRP'),(30907,70866,'sterol-dependent protein binding','F','Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) in the presence of sterols.','2013-10-27','NSRP'),(30908,70867,'mating projection tip membrane','C','The portion of the plasma membrane surrounding a mating projection tip.','2013-10-27','NSRP'),(30909,70868,'heterochromatin organization involved in chromatin silencing','P','Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing.','2013-10-27','NSRP'),(30910,70869,'heterochromatin assembly involved in chromatin silencing','P','Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.','2013-10-27','NSRP'),(30911,70870,'heterochromatin maintenance involved in chromatin silencing','P','A chromatin organization process that preserves heterochromatin in a stable functional or structural state, and that contributes to chromatin silencing.','2013-10-27','NSRP'),(30912,70871,'cell wall organization involved in conjugation with cellular fusion','P','A process of cell wall organization that contributes to conjugation with cellular fusion.','2013-10-27','NSRP'),(30913,70872,'plasma membrane organization involved in conjugation with cellular fusion','P','A process of plasma membrane organization that contributes to conjugation with cellular fusion.','2013-10-27','NSRP'),(30914,70873,'regulation of glycogen metabolic process','P','Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.','2013-10-27','NSRP'),(30915,70874,'negative regulation of glycogen metabolic process','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.','2013-10-27','NSRP'),(30916,70875,'positive regulation of glycogen metabolic process','P','Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.','2013-10-27','NSRP'),(30917,70876,'SOSS complex','C','A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.','2013-10-27','NSRP'),(30918,70877,'microprocessor complex','C','A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3\' and 5\' strands of a stem-loop to release hairpin-shaped pre-miRNAs.','2013-10-27','NSRP'),(30919,70878,'primary miRNA binding','F','Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.','2013-10-27','NSRP'),(30920,70879,'fungal-type cell wall beta-glucan metabolic process','P','The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.','2013-10-27','NSRP'),(30921,70880,'fungal-type cell wall beta-glucan biosynthetic process','P','The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.','2013-10-27','NSRP'),(30922,70881,'regulation of proline transport','P','Any process that modulates the frequency, rate or extent of proline transport.','2013-10-27','NSRP'),(30923,70882,'cellular cell wall organization or biogenesis','P','A cellular process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.','2012-03-14','NSRP'),(30924,70883,'pre-miRNA binding','F','Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.','2013-10-27','NSRP'),(30925,70884,'regulation of calcineurin-NFAT signaling cascade','P','Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.','2013-10-27','NSRP'),(30926,70885,'negative regulation of calcineurin-NFAT signaling cascade','P','Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.','2013-10-27','NSRP'),(30927,70886,'positive regulation of calcineurin-NFAT signaling cascade','P','Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.','2013-10-27','NSRP'),